𝕏

Task 55614480

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_4000-conf_912_0
Workunit 26408128
Created 1 Jul 2024, 15:38:01 UTC
Sent 2 Jul 2024, 3:16:48 UTC
Report deadline 5 Jul 2024, 3:16:48 UTC
Received 3 Jul 2024, 15:04:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 59 min 45 sec
CPU time 1 hours 30 min 6 sec
Validate state Valid
Credit 43.13
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_4000-conf_912.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_4000-conf_912_0_r2128001399_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_MID_4000-conf_912_0_r2128001399_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.435970
     * GNaL_b in INaL: 0.006087
     * Gto_b in Ito: 0.080853
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031568
     * GKs_b in IKs: 0.001913
     * GK1_b in IK1: 0.162890
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.454774
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033009
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8875643, states[0] = -94.199370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16952131, states[0] = -94.174233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 24449865, states[0] = -93.989658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33417737, states[0] = -94.170640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 41653480, states[0] = -94.173195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49812164, states[0] = -94.177373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 57897619, states[0] = -94.182254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67439874, states[0] = -94.198522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 76024368, states[0] = 34.160642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85574869, states[0] = -94.203975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93694303, states[0] = -94.204329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102203404, states[0] = -25.648170, states[40]= 0.006886
Saving checkpoint... 
Iteration: 110387572, states[0] = -93.997608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117918393, states[0] = -94.206547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125349117, states[0] = -94.220429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 133278076, states[0] = -94.223750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141179462, states[0] = -94.227957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 149697332, states[0] = -94.214302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158300155, states[0] = -93.667929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166311220, states[0] = -93.733954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174464806, states[0] = -94.134764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182391599, states[0] = -94.018658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190997166, states[0] = -94.236731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 200398636, states[0] = -94.034576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208864002, states[0] = -94.240066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 216615024, states[0] = -94.221037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 224447629, states[0] = -94.115637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233624699, states[0] = -94.217850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242358749, states[0] = -93.931564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250629221, states[0] = -94.224293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 258983559, states[0] = -94.237301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 266713970, states[0] = -94.236069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 275099043, states[0] = -94.233265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 282791548, states[0] = -94.239575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 291169143, states[0] = -94.230634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 300389897, states[0] = -94.015517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308527689, states[0] = -94.185976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317429792, states[0] = -94.222046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326269915, states[0] = -73.357508, states[40]= 0.000018
Saving checkpoint... 
Iteration: 335791739, states[0] = -94.213693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 345148950, states[0] = -94.230766, states[40]= 0.000001
Saving checkpoint... 
Iteration: 353398326, states[0] = -94.222539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 362044073, states[0] = 33.166560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372293833, states[0] = -93.602492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380132586, states[0] = 3.480349, states[40]= 0.000192
Saving checkpoint... 
Iteration: 389357918, states[0] = -94.223317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398836616, states[0] = -94.238679, states[40]= 0.000001
Saving checkpoint... 
Iteration: 407019359, states[0] = -94.234575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415977038, states[0] = -94.209893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424189573, states[0] = -22.479375, states[40]= 0.004951
Saving checkpoint... 
Iteration: 432731799, states[0] = -94.235528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441635603, states[0] = -94.215508, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450227144, states[0] = -38.199140, states[40]= 0.002859
Saving checkpoint... 
Iteration: 458779168, states[0] = -94.237293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467271621, states[0] = -94.225119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 475372782, states[0] = -94.221849, states[40]= 0.000001
Saving checkpoint... 
Iteration: 483948085, states[0] = -94.209482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493325054, states[0] = -94.223093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 502894969, states[0] = -94.236838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 511200835, states[0] = -94.226986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520190325, states[0] = -22.704444, states[40]= 0.005122
Saving checkpoint... 
Iteration: 528776320, states[0] = -94.236379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 536961266, states[0] = -94.234842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545280810, states[0] = -94.223887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553725480, states[0] = -94.212332, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562468916, states[0] = -94.136667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571260132, states[0] = -94.224256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579417103, states[0] = -94.219316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588276335, states[0] = -83.807243, states[40]= 0.000004
Saving checkpoint... 
Iteration: 596488866, states[0] = -94.155002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604783598, states[0] = -94.235664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 613857272, states[0] = -94.209292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622437415, states[0] = -94.097773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630659014, states[0] = -94.225516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 639458414, states[0] = -94.217454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 648685206, states[0] = -94.228855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 656859679, states[0] = -94.235485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 665606367, states[0] = -94.213477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 674160395, states[0] = -9.143668, states[40]= 0.000687
Saving checkpoint... 
Iteration: 682804007, states[0] = -94.235109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691389459, states[0] = -94.218774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 700227171, states[0] = -38.207840, states[40]= 0.002856
Saving checkpoint... 
Iteration: 709462376, states[0] = -94.216510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717164489, states[0] = -94.225795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 725744678, states[0] = -94.209909, states[40]= 0.000001
Saving checkpoint... 
Iteration: 736471905, states[0] = -94.137618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744928186, states[0] = -94.233239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753076633, states[0] = -94.228476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760880528, states[0] = -94.233995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 769218644, states[0] = -94.223290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 777846362, states[0] = -94.207507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 786240014, states[0] = -46.834683, states[40]= 0.000980
Saving checkpoint... 
Iteration: 794268231, states[0] = -71.082019, states[40]= 0.000026
Saving checkpoint... 
Iteration: 802033015, states[0] = 34.263562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809420417, states[0] = -94.216472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818401127, states[0] = -94.033589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826068304, states[0] = 26.922004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835004042, states[0] = -94.229971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841915555, states[0] = -94.205667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 850911082, states[0] = -94.232365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858451694, states[0] = -94.113706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867517799, states[0] = -94.213176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 875196114, states[0] = -94.222802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 884516547, states[0] = -94.172241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 893196233, states[0] = -94.222585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 901236083, states[0] = -94.221123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909330784, states[0] = -94.217945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917208715, states[0] = -94.221866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924904983, states[0] = -94.231611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932432157, states[0] = -94.086418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941400972, states[0] = -94.215454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949282855, states[0] = -94.218995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957478987, states[0] = -94.213105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965368794, states[0] = -94.216115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 973444412, states[0] = -94.213846, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980313689, states[0] = -93.741355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988340057, states[0] = -93.857491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996432995, states[0] = -94.086886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004613814, states[0] = -94.211942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013041924, states[0] = -94.226583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1021977160, states[0] = -94.202648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1029915293, states[0] = -94.203427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038754916, states[0] = -94.229524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046208409, states[0] = -28.715557, states[40]= 0.006315
Saving checkpoint... 
Iteration: 1054463406, states[0] = -94.124895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062782158, states[0] = -94.230163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071248995, states[0] = -94.218656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078748212, states[0] = -94.228736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1088391082, states[0] = -94.008747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096344286, states[0] = -93.872118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104512300, states[0] = -94.166775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1112244576, states[0] = -50.156088, states[40]= 0.000618
Saving checkpoint... 
Iteration: 1120641720, states[0] = -94.216679, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127943200, states[0] = -94.201849, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136225495, states[0] = -37.183609, states[40]= 0.003195
Saving checkpoint... 
Iteration: 1144850731, states[0] = -94.229729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1152839625, states[0] = -94.229680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160774775, states[0] = -94.228791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1169053586, states[0] = -94.224318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1177371979, states[0] = -94.213487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187203191, states[0] = -94.218832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195880237, states[0] = -94.201971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1203926654, states[0] = -94.201178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1212613850, states[0] = -94.209463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1220913351, states[0] = -94.227901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1229241469, states[0] = -94.217021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1237671434, states[0] = -94.205233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246940933, states[0] = -94.226927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1255664673, states[0] = -94.205160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263436861, states[0] = -94.210588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271915546, states[0] = -94.200527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280264412, states[0] = -66.635494, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1287694482, states[0] = -94.204165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1295740383, states[0] = -94.203176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1304138595, states[0] = 1.142359, states[40]= 0.000287
Saving checkpoint... 
Iteration: 1311622992, states[0] = -94.205384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1319334919, states[0] = -94.212916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327342814, states[0] = -94.212577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1335161526, states[0] = -94.218520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1343418629, states[0] = -94.210143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351778659, states[0] = -94.201802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359891188, states[0] = -94.199840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368950281, states[0] = -94.225219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377831017, states[0] = -94.200585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1386574581, states[0] = -94.195243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395527122, states[0] = -94.206631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1403281137, states[0] = -94.213626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1412283338, states[0] = -91.968412, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420671246, states[0] = -94.217874, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429402460, states[0] = -94.209581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1437394813, states[0] = -94.209708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445995785, states[0] = -94.197329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454761571, states[0] = -94.224833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464149870, states[0] = -3.709501, states[40]= 0.000520
Saving checkpoint... 
Iteration: 1472733115, states[0] = -94.223199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1480556971, states[0] = -94.186961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489097958, states[0] = -94.218939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498076456, states[0] = 24.178426, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.072598
 - CaMKt in component CaMK (millimolar): 0.002639
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.848953
 - nass in component intracellular_ions (millimolar): 7.849110
 - ki in component intracellular_ions (millimolar): 143.933913
 - kss in component intracellular_ions (millimolar): 143.933898
 - cansr in component intracellular_ions (millimolar): 1.839297
 - cajsr in component intracellular_ions (millimolar): 1.841033
 - cai in component intracellular_ions (millimolar): 0.000102
 - m in component INa (dimensionless): 0.003934
 - hf in component INa (dimensionless): 0.864849
 - hs in component INa (dimensionless): 0.864850
 - j in component INa (dimensionless): 0.864853
 - hsp in component INa (dimensionless): 0.697928
 - jp in component INa (dimensionless): 0.864855
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706787
 - hLp in component INaL (dimensionless): 0.512069
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.989935
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.995856
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.994656
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004541
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.009310
 - xs1 in component IKs (dimensionless): 0.054860
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997547
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
15:04:03 (58127): called boinc_finish(0)

</stderr_txt>
]]>


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