𝕏

Task 55600921

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_299_1
Workunit 26401350
Created 1 Jul 2024, 15:32:03 UTC
Sent 2 Jul 2024, 1:35:53 UTC
Report deadline 5 Jul 2024, 1:35:53 UTC
Received 2 Jul 2024, 5:40:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216914
Run time 3 hours 3 min 37 sec
CPU time 3 hours 1 min 25 sec
Validate state Valid
Credit 42.79
Device peak FLOPS 1.97 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 3.75 MB
Peak swap size 1.48 MB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_299.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_299_1_r412900481_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_299_1_r412900481_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.123757
     * GNaL_b in INaL: 0.005600
     * Gto_b in Ito: 0.088101
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032155
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.162173
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.716866
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030166
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8739329, states[0] = -8.055379, states[40]= 0.003529
Saving checkpoint... 
Iteration: 17647402, states[0] = -84.760003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 26566760, states[0] = -2.746831, states[40]= 0.000538
Saving checkpoint... 
Iteration: 35612483, states[0] = -66.349726, states[40]= 0.000018
Saving checkpoint... 
Iteration: 44758339, states[0] = -40.367839, states[40]= 0.000223
Saving checkpoint... 
Iteration: 53773887, states[0] = -62.951454, states[40]= 0.000024
Saving checkpoint... 
Iteration: 62761314, states[0] = -47.640635, states[40]= 0.000113
Saving checkpoint... 
Iteration: 71741734, states[0] = -22.711164, states[40]= 0.000251
Saving checkpoint... 
Iteration: 80718151, states[0] = 5.320134, states[40]= 0.000102
Saving checkpoint... 
Iteration: 89725418, states[0] = -2.826159, states[40]= 0.000253
Saving checkpoint... 
Iteration: 98796766, states[0] = -84.639671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107764771, states[0] = -59.298855, states[40]= 0.000032
Saving checkpoint... 
Iteration: 116755834, states[0] = -48.541294, states[40]= 0.000094
Saving checkpoint... 
Iteration: 125760738, states[0] = -56.342980, states[40]= 0.000044
Saving checkpoint... 
Iteration: 134767416, states[0] = -67.221446, states[40]= 0.000013
Saving checkpoint... 
Iteration: 143806523, states[0] = -84.891552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 152819750, states[0] = 34.791427, states[40]= 1.226469
Saving checkpoint... 
Iteration: 162032481, states[0] = 13.410550, states[40]= 0.000016
Saving checkpoint... 
Iteration: 171094251, states[0] = -63.052132, states[40]= 0.000021
Saving checkpoint... 
Iteration: 180471703, states[0] = -84.916803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189478726, states[0] = -85.003952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198502628, states[0] = 27.818008, states[40]= 0.000667
Saving checkpoint... 
Iteration: 207536034, states[0] = 7.410175, states[40]= 0.000063
Saving checkpoint... 
Iteration: 216575230, states[0] = -43.460510, states[40]= 0.000140
Saving checkpoint... 
Iteration: 225609111, states[0] = -84.027686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234637726, states[0] = -84.967970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 243688760, states[0] = 14.905782, states[40]= 0.000011
Saving checkpoint... 
Iteration: 252739312, states[0] = -44.824780, states[40]= 0.000126
Saving checkpoint... 
Iteration: 261905338, states[0] = -45.189033, states[40]= 0.000123
Saving checkpoint... 
Iteration: 270890647, states[0] = -26.535542, states[40]= 0.000239
Saving checkpoint... 
Iteration: 279844749, states[0] = 19.346659, states[40]= 0.000004
Saving checkpoint... 
Iteration: 288689315, states[0] = 11.418015, states[40]= 0.000026
Saving checkpoint... 
Iteration: 297675412, states[0] = 19.873466, states[40]= 0.000004
Saving checkpoint... 
Iteration: 306479348, states[0] = 28.618643, states[40]= 0.067693
Saving checkpoint... 
Iteration: 315477259, states[0] = 28.255901, states[40]= 0.105557
Saving checkpoint... 
Iteration: 324472039, states[0] = 28.767024, states[40]= 0.505102
Saving checkpoint... 
Iteration: 333460150, states[0] = -84.950651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342461660, states[0] = -84.976174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 351519734, states[0] = 8.908762, states[40]= 0.000046
Saving checkpoint... 
Iteration: 360483891, states[0] = 28.603465, states[40]= 0.001678
Saving checkpoint... 
Iteration: 369489381, states[0] = 26.281854, states[40]= 0.000166
Saving checkpoint... 
Iteration: 378489697, states[0] = 25.730528, states[40]= 0.000107
Saving checkpoint... 
Iteration: 387466124, states[0] = 28.337186, states[40]= 0.440907
Saving checkpoint... 
Iteration: 396344196, states[0] = 12.147161, states[40]= 0.000022
Saving checkpoint... 
Iteration: 405394891, states[0] = -50.338392, states[40]= 0.000079
Saving checkpoint... 
Iteration: 414191075, states[0] = -0.928042, states[40]= 0.000204
Saving checkpoint... 
Iteration: 423336362, states[0] = 15.631829, states[40]= 0.000009
Saving checkpoint... 
Iteration: 432663775, states[0] = 18.763902, states[40]= 0.000004
Saving checkpoint... 
Iteration: 441628966, states[0] = 27.738811, states[40]= 0.249716
Saving checkpoint... 
Iteration: 450570015, states[0] = -68.557426, states[40]= 0.000011
Saving checkpoint... 
Iteration: 459288084, states[0] = 29.845376, states[40]= 0.161515
Saving checkpoint... 
Iteration: 468087938, states[0] = -84.370999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 477084664, states[0] = -84.114722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486090954, states[0] = -84.614263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495092932, states[0] = -84.688554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504102447, states[0] = -84.852610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513169947, states[0] = 9.135067, states[40]= 0.000044
Saving checkpoint... 
Iteration: 522132706, states[0] = 28.991996, states[40]= 0.003111
Saving checkpoint... 
Iteration: 531263803, states[0] = -84.816530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 540269778, states[0] = -84.902861, states[40]= 0.000001
Saving checkpoint... 
Iteration: 549256105, states[0] = -84.723508, states[40]= 0.000001
Saving checkpoint... 
Iteration: 558235445, states[0] = -81.001157, states[40]= 0.000002
Saving checkpoint... 
Iteration: 567244753, states[0] = -84.368887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576214991, states[0] = -55.476340, states[40]= 0.000048
Saving checkpoint... 
Iteration: 585224012, states[0] = -69.747609, states[40]= 0.000009
Saving checkpoint... 
Iteration: 594581988, states[0] = -84.659429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603557157, states[0] = -72.243815, states[40]= 0.000007
Saving checkpoint... 
Iteration: 612559641, states[0] = -77.070767, states[40]= 0.000003
Saving checkpoint... 
Iteration: 621551712, states[0] = -66.708861, states[40]= 0.000014
Saving checkpoint... 
Iteration: 630556063, states[0] = -74.616058, states[40]= 0.000005
Saving checkpoint... 
Iteration: 639557275, states[0] = -77.489256, states[40]= 0.000003
Saving checkpoint... 
Iteration: 648515640, states[0] = -20.923785, states[40]= 0.000220
Saving checkpoint... 
Iteration: 657490180, states[0] = 8.101430, states[40]= 0.000055
Saving checkpoint... 
Iteration: 666492751, states[0] = 5.249686, states[40]= 0.000092
Saving checkpoint... 
Iteration: 675792306, states[0] = 26.187550, states[40]= 0.000153
Saving checkpoint... 
Iteration: 684982406, states[0] = 11.864038, states[40]= 0.000024
Saving checkpoint... 
Iteration: 693974753, states[0] = 16.419249, states[40]= 0.000007
Saving checkpoint... 
Iteration: 702974573, states[0] = 15.956582, states[40]= 0.000008
Saving checkpoint... 
Iteration: 711973449, states[0] = 16.101502, states[40]= 0.000008
Saving checkpoint... 
Iteration: 720979452, states[0] = 11.402582, states[40]= 0.000027
Saving checkpoint... 
Iteration: 729981066, states[0] = 9.546238, states[40]= 0.000041
Saving checkpoint... 
Iteration: 738988971, states[0] = 2.098304, states[40]= 0.000147
Saving checkpoint... 
Iteration: 747714272, states[0] = -78.826625, states[40]= 0.000002
Saving checkpoint... 
Iteration: 756767676, states[0] = 28.632069, states[40]= 0.066923
Saving checkpoint... 
Iteration: 765696876, states[0] = -56.581293, states[40]= 0.000042
Saving checkpoint... 
Iteration: 774690701, states[0] = -49.519388, states[40]= 0.000084
Saving checkpoint... 
Iteration: 783506464, states[0] = -27.069918, states[40]= 0.000239
Saving checkpoint... 
Iteration: 792497767, states[0] = -15.825025, states[40]= 0.000238
Saving checkpoint... 
Iteration: 801687484, states[0] = -48.832653, states[40]= 0.000090
Saving checkpoint... 
Iteration: 810677038, states[0] = -36.157015, states[40]= 0.000214
Saving checkpoint... 
Iteration: 819638449, states[0] = 9.788442, states[40]= 0.000038
Saving checkpoint... 
Iteration: 828636123, states[0] = 10.846210, states[40]= 0.000030
Saving checkpoint... 
Iteration: 837938954, states[0] = 27.733918, states[40]= 0.000603
Saving checkpoint... 
Iteration: 846921954, states[0] = 27.746900, states[40]= 0.233105
Saving checkpoint... 
Iteration: 855940632, states[0] = 26.337338, states[40]= 0.000172
Saving checkpoint... 
Iteration: 864977834, states[0] = 0.657937, states[40]= 0.000174
Saving checkpoint... 
Iteration: 874010898, states[0] = -45.277538, states[40]= 0.000121
Saving checkpoint... 
Iteration: 883000955, states[0] = -33.194456, states[40]= 0.000235
Saving checkpoint... 
Iteration: 892050369, states[0] = -84.587371, states[40]= 0.000001
Saving checkpoint... 
Iteration: 900880709, states[0] = -84.506236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 910097811, states[0] = 27.942532, states[40]= 0.000747
Saving checkpoint... 
Iteration: 919450513, states[0] = 17.493329, states[40]= 0.000005
Saving checkpoint... 
Iteration: 928443441, states[0] = 21.176146, states[40]= 0.000006
Saving checkpoint... 
Iteration: 937502423, states[0] = -42.461891, states[40]= 0.000150
Saving checkpoint... 
Iteration: 945994501, states[0] = -32.979160, states[40]= 0.000236
Saving checkpoint... 
Iteration: 954989766, states[0] = -27.687675, states[40]= 0.000241
Saving checkpoint... 
Iteration: 963816548, states[0] = -19.601457, states[40]= 0.000221
Saving checkpoint... 
Iteration: 972814257, states[0] = -17.563613, states[40]= 0.000228
Saving checkpoint... 
Iteration: 981763029, states[0] = 25.590170, states[40]= 0.000095
Saving checkpoint... 
Iteration: 990757525, states[0] = 27.547268, states[40]= 0.000499
Saving checkpoint... 
Iteration: 999751801, states[0] = 28.963769, states[40]= 0.002893
Saving checkpoint... 
Iteration: 1008462895, states[0] = 1.256366, states[40]= 0.000163
Saving checkpoint... 
Iteration: 1017456871, states[0] = 5.925283, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1026075691, states[0] = 29.038002, states[40]= 0.036461
Saving checkpoint... 
Iteration: 1035066477, states[0] = 31.070559, states[40]= 0.755241
Saving checkpoint... 
Iteration: 1044023335, states[0] = -82.844640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1053008268, states[0] = -66.195065, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1062000731, states[0] = -56.763834, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1070775172, states[0] = 13.266826, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1079746992, states[0] = 28.116155, states[40]= 0.000902
Saving checkpoint... 
Iteration: 1088851544, states[0] = -82.538304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1097826552, states[0] = -51.484356, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1106758412, states[0] = 21.480550, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1115763274, states[0] = 18.081202, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1124763511, states[0] = 17.372419, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1133760479, states[0] = 18.690108, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1142744511, states[0] = 26.677687, states[40]= 0.000227
Saving checkpoint... 
Iteration: 1151709686, states[0] = -84.875995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160697336, states[0] = -84.724427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1169672553, states[0] = -79.274180, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1178656642, states[0] = -57.992733, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1187599533, states[0] = 11.356477, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1196587735, states[0] = 18.565910, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1205584499, states[0] = 19.961060, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1214590777, states[0] = 15.514837, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1223574748, states[0] = 24.339374, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1232569816, states[0] = 26.263667, states[40]= 0.000161
Saving checkpoint... 
Iteration: 1241573862, states[0] = 23.871355, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1250559325, states[0] = 29.100493, states[40]= 0.003779
Saving checkpoint... 
Iteration: 1259506135, states[0] = -84.008248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268479537, states[0] = -56.001622, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1277333821, states[0] = -83.021291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1286329304, states[0] = -80.893158, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1295315909, states[0] = -64.016533, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1304299355, states[0] = -42.807535, states[40]= 0.000146
Saving checkpoint... 
Iteration: 1313267094, states[0] = -0.104248, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1322247960, states[0] = 14.667370, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1331242437, states[0] = 17.646539, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1340241727, states[0] = 17.527123, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1349240267, states[0] = 17.873291, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1358247965, states[0] = 12.198171, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1367256050, states[0] = 5.231415, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1376213509, states[0] = 29.090072, states[40]= 0.003662
Saving checkpoint... 
Iteration: 1385185066, states[0] = -84.846289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394098845, states[0] = -7.950501, states[40]= 0.000278
Saving checkpoint... 
Iteration: 1402979550, states[0] = -75.517282, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1411929332, states[0] = -6.518496, states[40]= 0.000273
Saving checkpoint... 
Iteration: 1420892421, states[0] = 22.181607, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1429874766, states[0] = 29.098624, states[40]= 0.003720
Saving checkpoint... 
Iteration: 1438565773, states[0] = 17.187777, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1447565227, states[0] = 16.964983, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1456569211, states[0] = 13.763507, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1465559697, states[0] = 19.259159, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1474510547, states[0] = -84.853194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483516319, states[0] = -84.925434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492438794, states[0] = -31.486799, states[40]= 0.000241
Saving checkpoint... 
Iteration: 1499457051, states[0] = -56.802866, states[40]= 0.000041
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.820034
 - CaMKt in component CaMK (millimolar): 0.220479
 - cass in component intracellular_ions (millimolar): 0.000173
 - nai in component intracellular_ions (millimolar): 7.323977
 - nass in component intracellular_ions (millimolar): 7.324334
 - ki in component intracellular_ions (millimolar): 143.771587
 - kss in component intracellular_ions (millimolar): 143.771552
 - cansr in component intracellular_ions (millimolar): 3.366134
 - cajsr in component intracellular_ions (millimolar): 1.931987
 - cai in component intracellular_ions (millimolar): 0.000163
 - m in component INa (dimensionless): 0.009984
 - hf in component INa (dimensionless): 0.583177
 - hs in component INa (dimensionless): 0.582098
 - j in component INa (dimensionless): 0.552613
 - hsp in component INa (dimensionless): 0.330653
 - jp in component INa (dimensionless): 0.511107
 - mL in component INaL (dimensionless): 0.000336
 - hL in component INaL (dimensionless): 0.182946
 - hLp in component INaL (dimensionless): 0.074585
 - a in component Ito (dimensionless): 0.001231
 - iF in component Ito (dimensionless): 0.999233
 - iS in component Ito (dimensionless): 0.131506
 - ap in component Ito (dimensionless): 0.000627
 - iFp in component Ito (dimensionless): 0.999234
 - iSp in component Ito (dimensionless): 0.147084
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.678380
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.929651
 - jca in component ICaL (dimensionless): 0.911823
 - ffp in component ICaL (dimensionless): 0.998950
 - fcafp in component ICaL (dimensionless): 0.999941
 - nca in component ICaL (dimensionless): 0.043052
 - xrf in component IKr (dimensionless): 0.100346
 - xrs in component IKr (dimensionless): 0.871750
 - xs1 in component IKs (dimensionless): 0.570005
 - xs2 in component IKs (dimensionless): 0.007121
 - xk1 in component IK1 (dimensionless): 0.996743
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
00:39:29 (2324): called boinc_finish(0)

</stderr_txt>
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