𝕏

Task 55594321

Name HuVeMOp_20240630011100300215_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_119_3
Workunit 26286464
Created 1 Jul 2024, 15:29:09 UTC
Sent 2 Jul 2024, 0:39:22 UTC
Report deadline 5 Jul 2024, 3:32:10 UTC
Received 5 Jul 2024, 4:19:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240430
Run time 3 hours 11 min 56 sec
CPU time 2 hours 22 min 5 sec
Validate state Valid
Credit 49.10
Device peak FLOPS 3.32 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.34 MB
Peak swap size 6.21 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_119.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_119_3_r1540288765_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_119_3_r1540288765_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 101.932002
     * GNaL_b in INaL: 0.006480
     * Gto_b in Ito: 0.079046
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030898
     * GKs_b in IKs: 0.000105
     * GK1_b in IK1: 0.157916
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.537457
     * GKb_b in IKb: 0.003787
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029031
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9442194, states[0] = -94.767056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19041526, states[0] = 21.597349, states[40]= 0.002607
Saving checkpoint... 
Iteration: 28687368, states[0] = -93.503666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38373428, states[0] = -94.656343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48018807, states[0] = 28.198302, states[40]= 0.003564
Saving checkpoint... 
Iteration: 57606127, states[0] = -11.794979, states[40]= 0.002367
Saving checkpoint... 
Iteration: 67219917, states[0] = -94.343119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76867826, states[0] = -94.642010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86467817, states[0] = -94.693266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96189623, states[0] = -93.625407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105840109, states[0] = -94.613196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115364419, states[0] = -94.636783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125113627, states[0] = -18.261365, states[40]= 0.001538
Saving checkpoint... 
Iteration: 134663084, states[0] = -64.377522, states[40]= 0.000011
Saving checkpoint... 
Iteration: 144303105, states[0] = -94.561490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153918471, states[0] = -94.671795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163508232, states[0] = 29.089190, states[40]= 0.087567
Saving checkpoint... 
Iteration: 173085984, states[0] = 3.038580, states[40]= 0.004927
Saving checkpoint... 
Iteration: 182700200, states[0] = -94.229363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192223143, states[0] = -94.350803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201895648, states[0] = -94.658612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211478511, states[0] = -94.693457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221047739, states[0] = 19.776813, states[40]= 0.002657
Saving checkpoint... 
Iteration: 230631841, states[0] = -34.033930, states[40]= 0.000918
Saving checkpoint... 
Iteration: 240175296, states[0] = -80.470257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 249714660, states[0] = -94.316970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259218774, states[0] = -94.333514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268798179, states[0] = -94.552181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278482375, states[0] = -94.694141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288024817, states[0] = 27.089914, states[40]= 0.001697
Saving checkpoint... 
Iteration: 297554722, states[0] = 17.209963, states[40]= 0.003218
Saving checkpoint... 
Iteration: 307073523, states[0] = 9.411726, states[40]= 0.004602
Saving checkpoint... 
Iteration: 316702223, states[0] = -94.249974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326154863, states[0] = -55.740348, states[40]= 0.000047
Saving checkpoint... 
Iteration: 335725310, states[0] = -94.358294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345410440, states[0] = -94.666564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354792764, states[0] = -94.542059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364409885, states[0] = -94.666188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374102114, states[0] = -8.103337, states[40]= 0.003203
Saving checkpoint... 
Iteration: 383745849, states[0] = -94.428182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393412054, states[0] = -94.667233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402931737, states[0] = -94.676630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412561323, states[0] = 14.650376, states[40]= 0.003760
Saving checkpoint... 
Iteration: 422159617, states[0] = -60.605059, states[40]= 0.000021
Saving checkpoint... 
Iteration: 431724116, states[0] = -94.353418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441437427, states[0] = -94.678865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451066680, states[0] = 12.444024, states[40]= 0.004169
Saving checkpoint... 
Iteration: 460703193, states[0] = -94.257388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470284219, states[0] = -94.524955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479920963, states[0] = -94.671395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489682990, states[0] = -90.632415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499360487, states[0] = -94.630776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508833953, states[0] = -94.603156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518384710, states[0] = -94.650012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528048213, states[0] = 19.607049, states[40]= 0.002694
Saving checkpoint... 
Iteration: 537591017, states[0] = 0.024341, states[40]= 0.004750
Saving checkpoint... 
Iteration: 547228149, states[0] = -94.367921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556765062, states[0] = -94.481134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565189505, states[0] = -93.576707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573142901, states[0] = -44.050825, states[40]= 0.000270
Saving checkpoint... 
Iteration: 582702639, states[0] = -94.252447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592366526, states[0] = -94.635681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601981845, states[0] = -94.692706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611700381, states[0] = -94.229605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621321724, states[0] = -94.587140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630911447, states[0] = -94.665960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640492043, states[0] = -94.695015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650000430, states[0] = -40.339839, states[40]= 0.000009
Saving checkpoint... 
Iteration: 659584214, states[0] = 4.032665, states[40]= 0.004935
Saving checkpoint... 
Iteration: 669275623, states[0] = -94.505769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678968633, states[0] = -94.688775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688435032, states[0] = -94.676889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698082854, states[0] = 4.770700, states[40]= 0.004926
Saving checkpoint... 
Iteration: 707706292, states[0] = -94.276469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717291655, states[0] = -94.538526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726817253, states[0] = -94.580498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736398375, states[0] = -94.658082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746100033, states[0] = -6.406244, states[40]= 0.003607
Saving checkpoint... 
Iteration: 755625013, states[0] = -28.106964, states[40]= 0.001409
Saving checkpoint... 
Iteration: 765228852, states[0] = -94.369594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774827609, states[0] = -94.594267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784274571, states[0] = -94.502934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793802577, states[0] = -94.557578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803385983, states[0] = -94.649758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813067697, states[0] = 12.010441, states[40]= 0.004241
Saving checkpoint... 
Iteration: 822769201, states[0] = -94.490239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832408294, states[0] = -94.663446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842045047, states[0] = 20.738610, states[40]= 0.002458
Saving checkpoint... 
Iteration: 851495727, states[0] = -94.694996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860992229, states[0] = -94.694176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870622599, states[0] = -26.030661, states[40]= 0.001490
Saving checkpoint... 
Iteration: 880252218, states[0] = -94.445182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889856996, states[0] = -94.626005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899521161, states[0] = 27.872618, states[40]= 0.002336
Saving checkpoint... 
Iteration: 909098616, states[0] = -5.294932, states[40]= 0.003862
Saving checkpoint... 
Iteration: 918605366, states[0] = -10.878617, states[40]= 0.002561
Saving checkpoint... 
Iteration: 928212625, states[0] = -94.305653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937908050, states[0] = -94.662890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947530827, states[0] = 25.460702, states[40]= 0.001668
Saving checkpoint... 
Iteration: 957148234, states[0] = -49.172255, states[40]= 0.000129
Saving checkpoint... 
Iteration: 966603587, states[0] = -9.342736, states[40]= 0.002908
Saving checkpoint... 
Iteration: 976244378, states[0] = -94.421212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985805006, states[0] = -94.560808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995369415, states[0] = -94.636477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004933632, states[0] = -94.675034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014487488, states[0] = -94.692454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024181482, states[0] = -89.175940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033632994, states[0] = -35.042309, states[40]= 0.000828
Saving checkpoint... 
Iteration: 1043261730, states[0] = -94.470637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052909753, states[0] = -94.663361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062531544, states[0] = 25.245410, states[40]= 0.001692
Saving checkpoint... 
Iteration: 1072147114, states[0] = -48.081817, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1081677898, states[0] = -84.461960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091287422, states[0] = -94.528874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100789640, states[0] = -94.533151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110340087, states[0] = -94.607820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119923252, states[0] = -94.669928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129527938, states[0] = 26.288101, states[40]= 0.001613
Saving checkpoint... 
Iteration: 1139189340, states[0] = -93.542327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148823076, states[0] = -94.586844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158418538, states[0] = -94.667494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168124576, states[0] = -27.729349, states[40]= 0.001429
Saving checkpoint... 
Iteration: 1177719750, states[0] = -94.333607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187286405, states[0] = -94.526473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196873728, states[0] = -94.639136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206456610, states[0] = -94.682897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215957524, states[0] = -94.683163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225510260, states[0] = 28.805167, states[40]= 0.044526
Saving checkpoint... 
Iteration: 1235146927, states[0] = -47.899666, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1244817876, states[0] = -94.579302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254491989, states[0] = -94.692549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264172888, states[0] = -76.786891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273874986, states[0] = -94.639810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283482135, states[0] = -94.690056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293083244, states[0] = 4.562067, states[40]= 0.004930
Saving checkpoint... 
Iteration: 1302703796, states[0] = -94.258395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312269814, states[0] = -94.489733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321765751, states[0] = -94.479773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331432186, states[0] = -94.673111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340984021, states[0] = -94.690302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350666504, states[0] = -68.261627, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1360303824, states[0] = -94.557368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369914242, states[0] = -94.664472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379511114, states[0] = 28.772107, states[40]= 0.033575
Saving checkpoint... 
Iteration: 1388970184, states[0] = -94.686390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398705738, states[0] = -94.270485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408237872, states[0] = -94.398415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417856329, states[0] = -94.623263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427432435, states[0] = -94.672834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437002950, states[0] = 39.355473, states[40]= 0.452388
Saving checkpoint... 
Iteration: 1446662164, states[0] = -63.313159, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1456179775, states[0] = -87.115043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465718216, states[0] = -94.326390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475305599, states[0] = -94.559801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484933971, states[0] = -94.673258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494459315, states[0] = -94.682637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504038777, states[0] = -21.601561, states[40]= 0.001578
Saving checkpoint... 
Iteration: 1513600366, states[0] = -24.695555, states[40]= 0.001814
Saving checkpoint... 
Iteration: 1523156886, states[0] = -20.777322, states[40]= 0.001696
Saving checkpoint... 
Iteration: 1532703249, states[0] = -94.703352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542200888, states[0] = -94.572169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551730655, states[0] = -94.538833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561151369, states[0] = -41.826433, states[40]= 0.000390
Saving checkpoint... 
Iteration: 1570783612, states[0] = -94.463079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580406184, states[0] = -94.308769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589928831, states[0] = -94.358757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599432170, states[0] = -94.336586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609052453, states[0] = -94.326159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618514989, states[0] = -94.273381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627995767, states[0] = -94.229764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637482093, states[0] = -94.234643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646949504, states[0] = -94.233073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656497515, states[0] = -94.234536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665934706, states[0] = -94.243161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675564224, states[0] = -94.226023, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.093858
 - CaMKt in component CaMK (millimolar): 0.001156
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.427174
 - nass in component intracellular_ions (millimolar): 6.427261
 - ki in component intracellular_ions (millimolar): 145.465848
 - kss in component intracellular_ions (millimolar): 145.465838
 - cansr in component intracellular_ions (millimolar): 1.583063
 - cajsr in component intracellular_ions (millimolar): 1.583069
 - cai in component intracellular_ions (millimolar): 0.000091
 - m in component INa (dimensionless): 0.003926
 - hf in component INa (dimensionless): 0.865257
 - hs in component INa (dimensionless): 0.865257
 - j in component INa (dimensionless): 0.865259
 - hsp in component INa (dimensionless): 0.698662
 - jp in component INa (dimensionless): 0.865259
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707349
 - hLp in component INaL (dimensionless): 0.513565
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.997646
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999204
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998803
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003123
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001960
 - xs1 in component IKs (dimensionless): 0.023698
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997541
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:19:04 (12216): called boinc_finish(0)

</stderr_txt>
]]>


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