𝕏

Task 55586912

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_986_1
Workunit 26394458
Created 1 Jul 2024, 15:25:52 UTC
Sent 1 Jul 2024, 23:52:53 UTC
Report deadline 4 Jul 2024, 23:52:53 UTC
Received 2 Jul 2024, 5:51:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241398
Run time 2 hours 53 min 50 sec
CPU time 2 hours 53 min 50 sec
Validate state Valid
Credit 46.17
Device peak FLOPS 1.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 3.11 MB
Peak swap size 4.15 MB
Peak disk usage 0.95 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_986.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_986_1_r1872681643_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_986_1_r1872681643_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.743374
     * GNaL_b in INaL: 0.005660
     * Gto_b in Ito: 0.085851
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032087
     * GKs_b in IKs: 0.001920
     * GK1_b in IK1: 0.167829
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.292656
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1498500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9586605, states[0] = -84.327117, states[40]= 0.000001
Saving checkpoint... 
Iteration: 19122453, states[0] = -84.229043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 28881005, states[0] = -84.044807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 38474808, states[0] = -84.147007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48005213, states[0] = 28.609771, states[40]= 0.292867
Saving checkpoint... 
Iteration: 57637533, states[0] = -84.111649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67333334, states[0] = -84.083950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77201998, states[0] = -84.097127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86748780, states[0] = -84.072801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 96370854, states[0] = -83.928206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106049135, states[0] = -84.073616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 115695580, states[0] = -81.693516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125327571, states[0] = -84.077808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134944911, states[0] = -84.049559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144513022, states[0] = -84.041045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 154242633, states[0] = -84.055279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 163825762, states[0] = -83.823208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 173339698, states[0] = -84.071944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182797537, states[0] = -84.050919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192287804, states[0] = -83.705532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201779159, states[0] = -84.071910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 211410169, states[0] = -84.045423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220968808, states[0] = -84.014155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 230553131, states[0] = -84.060882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 240264172, states[0] = -83.607059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249883936, states[0] = -84.068327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 259610152, states[0] = -4.432547, states[40]= 0.001075
Saving checkpoint... 
Iteration: 269411251, states[0] = -84.067050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278989625, states[0] = -84.041643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 288611895, states[0] = -84.061998, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298340048, states[0] = -84.047115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 308016632, states[0] = -84.037482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317835587, states[0] = -84.047190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 327542381, states[0] = -84.046458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337147136, states[0] = -84.055468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 346779417, states[0] = -83.671516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356587614, states[0] = -84.058259, states[40]= 0.000001
Saving checkpoint... 
Iteration: 366386169, states[0] = -83.933911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376227810, states[0] = -84.051558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 385935626, states[0] = -83.988370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 395517931, states[0] = -84.061506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 405138631, states[0] = -29.040945, states[40]= 0.000587
Saving checkpoint... 
Iteration: 414618521, states[0] = -84.062367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424277665, states[0] = -84.049173, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_986.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_986_1_r1872681643_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_986_1_r1872681643_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.743374
     * GNaL_b in INaL: 0.005660
     * Gto_b in Ito: 0.085851
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032087
     * GKs_b in IKs: 0.001920
     * GK1_b in IK1: 0.167829
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.292656
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033365
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1498500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 424277665
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.049173 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 433681607, states[0] = -68.893092, states[40]= 0.000003
Saving checkpoint... 
Iteration: 443387795, states[0] = -84.067169, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452941201, states[0] = -84.042568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462695205, states[0] = -84.068713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 472261569, states[0] = -84.049690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 481805931, states[0] = -83.764015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491301413, states[0] = -84.069524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 501045104, states[0] = 24.521036, states[40]= 0.000046
Saving checkpoint... 
Iteration: 510573398, states[0] = -84.053974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520146887, states[0] = -84.054767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529692746, states[0] = -79.998218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539272880, states[0] = -84.069685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 548912980, states[0] = -84.043249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 558405190, states[0] = -83.957252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 568052185, states[0] = -84.059184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577314563, states[0] = -84.047035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587027343, states[0] = -84.040432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 596642449, states[0] = -84.054693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 606125339, states[0] = -17.305925, states[40]= 0.000586
Saving checkpoint... 
Iteration: 615628156, states[0] = -84.062853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 625140924, states[0] = -84.054659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 634698107, states[0] = -82.218880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644217326, states[0] = -84.068802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 653765671, states[0] = -84.048832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 663193474, states[0] = -80.429851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672667460, states[0] = -84.066357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 682109613, states[0] = -84.055955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691623859, states[0] = -15.949486, states[40]= 0.000622
Saving checkpoint... 
Iteration: 701188937, states[0] = -84.067532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710839119, states[0] = -84.045527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720519746, states[0] = -84.037101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730056519, states[0] = -84.058367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 739714608, states[0] = -83.320130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749319534, states[0] = -84.068192, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759019864, states[0] = 30.770681, states[40]= 0.001727
Saving checkpoint... 
Iteration: 768611149, states[0] = -84.059994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778200857, states[0] = -84.051273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787808848, states[0] = -83.771668, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797404757, states[0] = -84.065173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807054294, states[0] = 21.230021, states[40]= 0.000081
Saving checkpoint... 
Iteration: 816624330, states[0] = -84.061629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826259660, states[0] = -84.048450, states[40]= 0.000001
Saving checkpoint... 
Iteration: 835852815, states[0] = -83.877495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 845497665, states[0] = -84.060798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 854914335, states[0] = -84.042054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864476914, states[0] = -84.016053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874057081, states[0] = -84.057802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883744733, states[0] = -83.507695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893418765, states[0] = -84.064231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 902898047, states[0] = -84.042490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 912360904, states[0] = -83.892142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921940494, states[0] = -84.063175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931532815, states[0] = 28.328354, states[40]= 0.000040
Saving checkpoint... 
Iteration: 941127208, states[0] = -84.061524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950064665, states[0] = -84.050274, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957969669, states[0] = -84.061706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 966730462, states[0] = -84.067883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 976376588, states[0] = -84.043043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 985749390, states[0] = -83.531718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995162641, states[0] = -84.064802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1004693945, states[0] = -84.050745, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1014293448, states[0] = -83.721185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023731911, states[0] = -84.067695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033211230, states[0] = -84.049844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042740458, states[0] = -83.484009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052260835, states[0] = -84.067811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1061755375, states[0] = -84.047758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071358847, states[0] = -83.887855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080829739, states[0] = -84.066702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090449323, states[0] = -84.039888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1100053365, states[0] = -84.046756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109490775, states[0] = -84.060143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118985570, states[0] = -84.038502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128627650, states[0] = -84.060879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1138273512, states[0] = -84.046680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1147881542, states[0] = -83.924396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1157546303, states[0] = -84.057271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167163935, states[0] = -51.216722, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1176820914, states[0] = -84.066565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1186471550, states[0] = -84.038738, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196076261, states[0] = -84.052052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205614651, states[0] = -84.053756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215081569, states[0] = 10.306920, states[40]= 0.000394
Saving checkpoint... 
Iteration: 1224510870, states[0] = -84.031633, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1234147244, states[0] = -84.052083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243730152, states[0] = -83.425332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253262516, states[0] = -84.067061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1262766925, states[0] = -84.046501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272246223, states[0] = -83.514081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281868317, states[0] = -84.064758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1291551395, states[0] = 22.297347, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1301198515, states[0] = -84.065727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310784220, states[0] = -84.045574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320210352, states[0] = -83.258451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329701518, states[0] = -84.065739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339234388, states[0] = -84.047653, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348808223, states[0] = -83.767659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358457886, states[0] = -84.060758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1367988995, states[0] = -84.037452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377458941, states[0] = -84.002699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387139268, states[0] = -84.051892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1396801742, states[0] = -83.747391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406596138, states[0] = -84.053905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1416068316, states[0] = 15.797331, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1425713444, states[0] = -84.065782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435243493, states[0] = -84.046888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444984877, states[0] = -84.018358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454518161, states[0] = -84.057536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464185060, states[0] = -72.830851, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1473940728, states[0] = -84.061106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483458911, states[0] = -84.038074, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492958229, states[0] = -84.001773, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.912540
 - CaMKt in component CaMK (millimolar): 0.002715
 - cass in component intracellular_ions (millimolar): 0.000090
 - nai in component intracellular_ions (millimolar): 6.211574
 - nass in component intracellular_ions (millimolar): 6.211681
 - ki in component intracellular_ions (millimolar): 145.671209
 - kss in component intracellular_ions (millimolar): 145.671195
 - cansr in component intracellular_ions (millimolar): 1.667290
 - cajsr in component intracellular_ions (millimolar): 1.667451
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.010935
 - hf in component INa (dimensionless): 0.546553
 - hs in component INa (dimensionless): 0.546557
 - j in component INa (dimensionless): 0.546573
 - hsp in component INa (dimensionless): 0.303237
 - jp in component INa (dimensionless): 0.546582
 - mL in component INaL (dimensionless): 0.000400
 - hL in component INaL (dimensionless): 0.383028
 - hLp in component INaL (dimensionless): 0.212139
 - a in component Ito (dimensionless): 0.001308
 - iF in component Ito (dimensionless): 0.999108
 - iS in component Ito (dimensionless): 0.948288
 - ap in component Ito (dimensionless): 0.000666
 - iFp in component Ito (dimensionless): 0.999108
 - iSp in component Ito (dimensionless): 0.962512
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990835
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003432
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.086058
 - xs1 in component IKs (dimensionless): 0.071959
 - xs2 in component IKs (dimensionless): 0.000300
 - xk1 in component IK1 (dimensionless): 0.996939
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
04:50:17 (1543): called boinc_finish(0)

</stderr_txt>
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