𝕏

Task 55586317

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_1000-conf_386_0
Workunit 26394161
Created 1 Jul 2024, 15:25:37 UTC
Sent 1 Jul 2024, 23:50:17 UTC
Report deadline 4 Jul 2024, 23:50:17 UTC
Received 2 Jul 2024, 6:44:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 15 min 50 sec
CPU time 2 hours 11 min 13 sec
Validate state Valid
Credit 41.63
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.41 MB
Peak swap size 2.35 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_1000-conf_386.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_1000-conf_386_0_r1789958647_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_1000-conf_386_0_r1789958647_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.943503
     * GNaL_b in INaL: 0.005609
     * Gto_b in Ito: 0.084304
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032139
     * GKs_b in IKs: 0.001943
     * GK1_b in IK1: 0.159806
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.057137
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028971
     * celltype in environment: 0.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11316624, states[0] = -94.230984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22660841, states[0] = -60.525035, states[40]= 0.000034
Saving checkpoint... 
Iteration: 34005044, states[0] = 33.615751, states[40]= 0.334759
Saving checkpoint... 
Iteration: 45296725, states[0] = -94.149649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56585210, states[0] = 5.586024, states[40]= 0.002472
Saving checkpoint... 
Iteration: 67888522, states[0] = -94.299324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79195716, states[0] = -93.565057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90527801, states[0] = 30.176340, states[40]= 0.000199
Saving checkpoint... 
Iteration: 101821590, states[0] = -94.220112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113052267, states[0] = 20.900437, states[40]= 0.000390
Saving checkpoint... 
Iteration: 124358582, states[0] = -94.277445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135652748, states[0] = -54.442339, states[40]= 0.000092
Saving checkpoint... 
Iteration: 146837009, states[0] = -94.248651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158192672, states[0] = -93.387750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169566754, states[0] = 14.481110, states[40]= 0.000962
Saving checkpoint... 
Iteration: 180914317, states[0] = -94.329170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192282954, states[0] = -94.134391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203569150, states[0] = 13.366071, states[40]= 0.001104
Saving checkpoint... 
Iteration: 214921157, states[0] = -94.333379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226128338, states[0] = -31.473917, states[40]= 0.001292
Saving checkpoint... 
Iteration: 237462825, states[0] = -94.353558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248821724, states[0] = -94.222855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260138259, states[0] = -40.656749, states[40]= 0.000568
Saving checkpoint... 
Iteration: 271438424, states[0] = -94.342493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282807661, states[0] = -94.194694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294142959, states[0] = -45.100770, states[40]= 0.000333
Saving checkpoint... 
Iteration: 305329435, states[0] = -94.235796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316637658, states[0] = -40.094564, states[40]= 0.000606
Saving checkpoint... 
Iteration: 327755755, states[0] = -94.042858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339087685, states[0] = 3.842680, states[40]= 0.002604
Saving checkpoint... 
Iteration: 350440800, states[0] = -94.342874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361707745, states[0] = -93.800062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373060346, states[0] = 17.367439, states[40]= 0.000652
Saving checkpoint... 
Iteration: 384438100, states[0] = -94.341177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395765262, states[0] = -94.076934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407127594, states[0] = -30.790505, states[40]= 0.001338
Saving checkpoint... 
Iteration: 418456983, states[0] = -94.349432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429813819, states[0] = -94.205904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441157620, states[0] = -59.258042, states[40]= 0.000044
Saving checkpoint... 
Iteration: 452415981, states[0] = -94.327772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463579922, states[0] = 8.096656, states[40]= 0.001920
Saving checkpoint... 
Iteration: 474880303, states[0] = -94.299261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486189644, states[0] = -92.954184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497474586, states[0] = -94.355114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508771180, states[0] = -94.095591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520037528, states[0] = 26.816422, states[40]= 0.000145
Saving checkpoint... 
Iteration: 531339717, states[0] = -94.249734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542654667, states[0] = -56.371470, states[40]= 0.000068
Saving checkpoint... 
Iteration: 553924572, states[0] = -94.332026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565280954, states[0] = -94.124982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576549693, states[0] = 21.957223, states[40]= 0.000325
Saving checkpoint... 
Iteration: 587839403, states[0] = -94.248676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599130833, states[0] = -33.769075, states[40]= 0.001112
Saving checkpoint... 
Iteration: 610405309, states[0] = -94.318801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621584857, states[0] = 5.457109, states[40]= 0.002359
Saving checkpoint... 
Iteration: 632853996, states[0] = -94.268431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644084963, states[0] = 5.398288, states[40]= 0.002369
Saving checkpoint... 
Iteration: 655369313, states[0] = -94.286206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666667152, states[0] = -69.279202, states[40]= 0.000009
Saving checkpoint... 
Iteration: 677947468, states[0] = -94.342638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689267029, states[0] = -94.079915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700574989, states[0] = 10.576503, states[40]= 0.001512
Saving checkpoint... 
Iteration: 711874514, states[0] = -94.291078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723018724, states[0] = 32.166764, states[40]= 0.002992
Saving checkpoint... 
Iteration: 734382942, states[0] = -94.299057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745704087, states[0] = -93.765414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757011722, states[0] = 32.152714, states[40]= 0.033873
Saving checkpoint... 
Iteration: 768305894, states[0] = -94.185816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779443194, states[0] = -94.339592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790652597, states[0] = -54.362870, states[40]= 0.000093
Saving checkpoint... 
Iteration: 801926838, states[0] = -94.330774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813256323, states[0] = -94.039933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824645814, states[0] = -47.826161, states[40]= 0.000233
Saving checkpoint... 
Iteration: 835879102, states[0] = -94.294355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847266116, states[0] = -94.075135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858557280, states[0] = 18.716611, states[40]= 0.000537
Saving checkpoint... 
Iteration: 869859279, states[0] = -94.272524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881130203, states[0] = -33.185489, states[40]= 0.001161
Saving checkpoint... 
Iteration: 892375320, states[0] = -94.290022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903693708, states[0] = -93.469402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914958248, states[0] = -94.344804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926062433, states[0] = 16.439573, states[40]= 0.000742
Saving checkpoint... 
Iteration: 937285382, states[0] = -94.133606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948529626, states[0] = 29.576624, states[40]= 0.000148
Saving checkpoint... 
Iteration: 959750540, states[0] = -94.015488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971015444, states[0] = 32.398920, states[40]= 0.009283
Saving checkpoint... 
Iteration: 982274106, states[0] = -94.099950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993530882, states[0] = 29.171060, states[40]= 0.000131
Saving checkpoint... 
Iteration: 1004759681, states[0] = -94.050555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016003878, states[0] = 36.448781, states[40]= 0.511745
Saving checkpoint... 
Iteration: 1027268252, states[0] = -94.080492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038532444, states[0] = 28.646914, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1049741999, states[0] = -93.977956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060978627, states[0] = -94.350593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072258934, states[0] = -94.047074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083323580, states[0] = -94.217549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094602318, states[0] = -6.652006, states[40]= 0.002749
Saving checkpoint... 
Iteration: 1105724705, states[0] = -93.892702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117009098, states[0] = 31.736588, states[40]= 0.084444
Saving checkpoint... 
Iteration: 1128239611, states[0] = -93.966290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139441675, states[0] = -94.335131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150714193, states[0] = -93.833367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161976175, states[0] = -94.348759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173239915, states[0] = -93.967209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184535485, states[0] = 27.573253, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1195767766, states[0] = -94.077088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207015296, states[0] = 32.400859, states[40]= 0.009772
Saving checkpoint... 
Iteration: 1218266218, states[0] = -94.071586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229527445, states[0] = 30.243197, states[40]= 0.000212
Saving checkpoint... 
Iteration: 1240668036, states[0] = -70.301305, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1251955450, states[0] = -94.340169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263160480, states[0] = -62.093944, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1274461853, states[0] = -94.342503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285712740, states[0] = -93.823154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296944010, states[0] = -94.334620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308215526, states[0] = -93.839556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319477370, states[0] = -94.347516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330740721, states[0] = -93.969221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341985424, states[0] = -94.349751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353241045, states[0] = -93.970453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364482102, states[0] = -94.348529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375719365, states[0] = -93.860750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386987351, states[0] = -94.349841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398059443, states[0] = 17.770391, states[40]= 0.000616
Saving checkpoint... 
Iteration: 1409255544, states[0] = -94.030656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420574203, states[0] = 10.963474, states[40]= 0.001453
Saving checkpoint... 
Iteration: 1431838264, states[0] = -94.238168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443117358, states[0] = -21.236820, states[40]= 0.001348
Saving checkpoint... 
Iteration: 1454255806, states[0] = -94.031194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465527940, states[0] = 30.097599, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1476878751, states[0] = -94.287358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488060077, states[0] = 17.490745, states[40]= 0.000642
Saving checkpoint... 
Iteration: 1499148746, states[0] = -50.636351, states[40]= 0.000159
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.227881
 - CaMKt in component CaMK (millimolar): 0.017823
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.052593
 - nass in component intracellular_ions (millimolar): 7.052717
 - ki in component intracellular_ions (millimolar): 144.723169
 - kss in component intracellular_ions (millimolar): 144.723149
 - cansr in component intracellular_ions (millimolar): 1.950110
 - cajsr in component intracellular_ions (millimolar): 1.905946
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003873
 - hf in component INa (dimensionless): 0.867806
 - hs in component INa (dimensionless): 0.867795
 - j in component INa (dimensionless): 0.867725
 - hsp in component INa (dimensionless): 0.703217
 - jp in component INa (dimensionless): 0.867675
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.685796
 - hLp in component INaL (dimensionless): 0.416172
 - a in component Ito (dimensionless): 0.000652
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.596652
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.662748
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.900943
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999762
 - jca in component ICaL (dimensionless): 0.999966
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004649
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.398165
 - xs1 in component IKs (dimensionless): 0.290044
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997509
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:39:20 (7117): called boinc_finish(0)

</stderr_txt>
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