𝕏

Task 55581036

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_10000-conf_481_0
Workunit 26391522
Created 1 Jul 2024, 15:23:18 UTC
Sent 1 Jul 2024, 23:26:31 UTC
Report deadline 4 Jul 2024, 23:26:31 UTC
Received 3 Jul 2024, 12:05:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 58 min 43 sec
CPU time 1 hours 30 min 4 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_10000-conf_481.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_10000-conf_481_0_r1550256980_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_10000-conf_481_0_r1550256980_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.124775
     * GNaL_b in INaL: 0.005804
     * Gto_b in Ito: 0.088099
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032041
     * GKs_b in IKs: 0.001957
     * GK1_b in IK1: 0.165371
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.477587
     * GKb_b in IKb: 0.003784
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034561
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8954915, states[0] = -94.105303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17528171, states[0] = -94.023673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26116264, states[0] = -93.996569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35829960, states[0] = -93.976048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44862755, states[0] = -93.921867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53705408, states[0] = -93.915108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61626916, states[0] = -93.927086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69310279, states[0] = -93.906419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77557399, states[0] = -93.910706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85159192, states[0] = -36.127261, states[40]= 0.001485
Saving checkpoint... 
Iteration: 93784831, states[0] = -93.903182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102516983, states[0] = -93.908052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110906230, states[0] = -93.940448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119493288, states[0] = -93.900227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128369298, states[0] = -93.902449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136441257, states[0] = -93.922359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144454766, states[0] = -93.899580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152814628, states[0] = -93.904356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160714826, states[0] = -93.940108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169065485, states[0] = -93.899899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177227555, states[0] = -93.908600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185656630, states[0] = -93.936334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194589502, states[0] = -93.898834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202508605, states[0] = -93.905933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211286419, states[0] = -93.925937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219473828, states[0] = -93.898893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227739846, states[0] = -93.904258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235969446, states[0] = -93.936695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243919503, states[0] = -93.899829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251202799, states[0] = -93.928506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258956409, states[0] = -93.899720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266462435, states[0] = -93.920886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275603325, states[0] = -93.929360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284166094, states[0] = -93.899267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291791374, states[0] = -93.914024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299590813, states[0] = -93.898568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307708641, states[0] = -93.904311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314971511, states[0] = -93.898068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322905628, states[0] = -93.903169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330818241, states[0] = -93.940428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338812648, states[0] = -93.899938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346870660, states[0] = -93.912681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354519907, states[0] = -93.898609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362424194, states[0] = -93.906318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370508140, states[0] = -93.902373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378829553, states[0] = -93.899857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388104987, states[0] = -93.902160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395436374, states[0] = -93.857778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404755716, states[0] = -93.898237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413030993, states[0] = -93.902465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421802811, states[0] = -93.913695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430351081, states[0] = -93.744962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437885029, states[0] = -93.903162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445558714, states[0] = -93.919668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453631750, states[0] = -93.900284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462269448, states[0] = -93.907628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470756456, states[0] = -93.940360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478766417, states[0] = -93.899912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486824207, states[0] = -93.913280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494634912, states[0] = -93.898310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503245709, states[0] = -93.901481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511857408, states[0] = -93.912727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519555519, states[0] = -93.898397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527078493, states[0] = -93.909658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535542899, states[0] = -93.915038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544721517, states[0] = -93.898147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551783560, states[0] = -93.913896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560472118, states[0] = -93.883557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570955814, states[0] = -93.936773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580486090, states[0] = -93.891527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589007052, states[0] = -93.899267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598184515, states[0] = -93.901628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606943516, states[0] = -93.911354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615727445, states[0] = -93.939656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625870776, states[0] = -93.939188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634068252, states[0] = -93.899102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643030263, states[0] = -93.902248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651084530, states[0] = -93.932188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660080844, states[0] = 14.005710, states[40]= 0.001758
Saving checkpoint... 
Iteration: 669161402, states[0] = -93.898891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677185013, states[0] = -93.908294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684906327, states[0] = -93.897783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694036027, states[0] = -93.899108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701932221, states[0] = -93.911424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710050613, states[0] = 25.005152, states[40]= 0.000371
Saving checkpoint... 
Iteration: 718006815, states[0] = -93.902286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726651599, states[0] = -93.916169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735041144, states[0] = 27.866939, states[40]= 0.000218
Saving checkpoint... 
Iteration: 743924565, states[0] = -93.899293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752543281, states[0] = -93.905005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760803635, states[0] = -93.940155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768820221, states[0] = -93.899505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777388228, states[0] = -93.906226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785736020, states[0] = -93.939711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793907719, states[0] = -93.899282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801695000, states[0] = -93.915251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810904722, states[0] = -93.938124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819254547, states[0] = -93.898582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827667268, states[0] = -93.904070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836358472, states[0] = -93.923098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845355948, states[0] = -93.753811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853693691, states[0] = -93.899737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861987636, states[0] = -93.910501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870852124, states[0] = -93.939362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879207409, states[0] = -93.898607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888059350, states[0] = -93.901882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897461223, states[0] = -93.905500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906764702, states[0] = -93.913882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914383733, states[0] = -93.898278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922963188, states[0] = -93.902300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931483861, states[0] = -93.919693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940025234, states[0] = 31.271092, states[40]= 0.000389
Saving checkpoint... 
Iteration: 948995344, states[0] = -93.898947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957450480, states[0] = -93.905530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965920339, states[0] = -93.937519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975020385, states[0] = 31.680248, states[40]= 0.001673
Saving checkpoint... 
Iteration: 983561379, states[0] = -93.899975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992536578, states[0] = -93.904825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002626200, states[0] = -93.904177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011267177, states[0] = -93.925660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019474821, states[0] = -93.898037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028301221, states[0] = -93.900773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037202699, states[0] = -93.907760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045587537, states[0] = -93.925731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054074645, states[0] = -93.898687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063300064, states[0] = -93.900744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072857461, states[0] = -93.902702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081445987, states[0] = -93.920500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089498085, states[0] = -93.897935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098461571, states[0] = -93.900166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107288138, states[0] = -93.906828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116474145, states[0] = -93.919756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125973402, states[0] = -93.935656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133356548, states[0] = -93.900478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141793808, states[0] = -93.913158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149935335, states[0] = -93.897304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158197098, states[0] = -93.901042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166475590, states[0] = -93.919673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174881626, states[0] = -93.897344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182962361, states[0] = -93.902055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191228440, states[0] = -93.926727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199681856, states[0] = -93.897572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207868583, states[0] = -93.902513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216210015, states[0] = -93.927308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224039078, states[0] = -93.898595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233335576, states[0] = -93.900455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242070278, states[0] = -93.909075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250484540, states[0] = -93.890052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260216658, states[0] = -88.234307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268915259, states[0] = -93.898811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277030415, states[0] = -93.909542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285223332, states[0] = -92.212699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293574286, states[0] = -93.899641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302341976, states[0] = -93.906136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310853946, states[0] = -93.938906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320059232, states[0] = 22.111325, states[40]= 0.000600
Saving checkpoint... 
Iteration: 1329235079, states[0] = -93.898128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337206560, states[0] = -93.907433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346527911, states[0] = -93.918246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356361275, states[0] = -93.922522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365328636, states[0] = -93.695117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374560180, states[0] = -93.897572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383249295, states[0] = -93.900625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391625219, states[0] = -93.916070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399853896, states[0] = -93.897162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408987573, states[0] = -93.898523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417008126, states[0] = -93.909697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425108113, states[0] = 1.260138, states[40]= 0.003826
Saving checkpoint... 
Iteration: 1432658231, states[0] = -93.903551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441207884, states[0] = -93.927164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449872087, states[0] = -93.897092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458044096, states[0] = -93.901405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465545943, states[0] = -93.915082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474178615, states[0] = -93.898090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482388503, states[0] = -93.905550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491771611, states[0] = -93.913203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499043447, states[0] = -93.898323, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.772883
 - CaMKt in component CaMK (millimolar): 0.001011
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.621250
 - nass in component intracellular_ions (millimolar): 6.621375
 - ki in component intracellular_ions (millimolar): 145.248319
 - kss in component intracellular_ions (millimolar): 145.248310
 - cansr in component intracellular_ions (millimolar): 1.831179
 - cajsr in component intracellular_ions (millimolar): 1.831100
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004055
 - hf in component INa (dimensionless): 0.858989
 - hs in component INa (dimensionless): 0.858989
 - j in component INa (dimensionless): 0.858989
 - hsp in component INa (dimensionless): 0.687442
 - jp in component INa (dimensionless): 0.858989
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698383
 - hLp in component INaL (dimensionless): 0.502915
 - a in component Ito (dimensionless): 0.000673
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.999838
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.999841
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999991
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005534
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002159
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997618
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:35:10 (54952): called boinc_finish(0)

</stderr_txt>
]]>


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