𝕏

Task 55581004

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_5000-conf_81_0
Workunit 26391506
Created 1 Jul 2024, 15:23:13 UTC
Sent 1 Jul 2024, 23:26:31 UTC
Report deadline 4 Jul 2024, 23:26:31 UTC
Received 3 Jul 2024, 12:05:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 59 min 4 sec
CPU time 1 hours 30 min 2 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 3.40 MB
Peak swap size 4.46 MB
Peak disk usage 1.56 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_5000-conf_81.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_5000-conf_81_0_r1892813883_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_5000-conf_81_0_r1892813883_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.423789
     * GNaL_b in INaL: 0.006075
     * Gto_b in Ito: 0.085483
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031563
     * GKs_b in IKs: 0.001944
     * GK1_b in IK1: 0.164529
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.639203
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035719
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9370802, states[0] = -94.701297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16931356, states[0] = -94.642486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26305551, states[0] = -94.601975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34525663, states[0] = -94.567827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42064512, states[0] = -94.550470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50070423, states[0] = 13.960641, states[40]= 0.003789
Saving checkpoint... 
Iteration: 58925668, states[0] = -94.533826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66958816, states[0] = -94.520932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75438491, states[0] = -94.473952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83583153, states[0] = -94.523410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90697643, states[0] = -94.521941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98027701, states[0] = -94.498573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106338970, states[0] = -94.511110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115303004, states[0] = -94.309337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123582042, states[0] = -94.512583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131685890, states[0] = -94.501785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138927289, states[0] = -94.504376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147686750, states[0] = -69.296856, states[40]= 0.000004
Saving checkpoint... 
Iteration: 155254295, states[0] = -94.180317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162907815, states[0] = -94.435495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170344954, states[0] = -94.372267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177849205, states[0] = -94.377458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186375230, states[0] = -94.502246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193843992, states[0] = -94.502536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202003064, states[0] = -94.494565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210229088, states[0] = -94.091118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218748700, states[0] = -94.503698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227399461, states[0] = -94.491621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235805821, states[0] = -94.510391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244538266, states[0] = -94.493675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252936333, states[0] = -94.451790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260768500, states[0] = -94.509902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268477891, states[0] = -94.508439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277271299, states[0] = -94.491934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285659244, states[0] = -94.505749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296043805, states[0] = -94.507107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305181036, states[0] = -62.914276, states[40]= 0.000012
Saving checkpoint... 
Iteration: 314626287, states[0] = -94.492731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323403279, states[0] = -94.509407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332094406, states[0] = -94.492918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340460702, states[0] = -94.463894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348861322, states[0] = -94.501047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357450422, states[0] = -94.490803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365886384, states[0] = -94.509541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373371750, states[0] = -94.509676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382679930, states[0] = -61.832110, states[40]= 0.000015
Saving checkpoint... 
Iteration: 391646281, states[0] = -94.496973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400274655, states[0] = -94.235908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408464722, states[0] = -94.508391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417549797, states[0] = 21.332645, states[40]= 0.002555
Saving checkpoint... 
Iteration: 426111373, states[0] = -94.505597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434362161, states[0] = -94.494679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442457942, states[0] = -94.490688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450789467, states[0] = -94.509762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459618877, states[0] = -94.492621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467926126, states[0] = -94.445316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477183778, states[0] = -94.492180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485215504, states[0] = -93.931338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493299773, states[0] = -94.509789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501325649, states[0] = -94.501517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511103275, states[0] = -94.505694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519812179, states[0] = -94.491384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529818280, states[0] = -94.491343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539546296, states[0] = -94.493081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548627871, states[0] = -94.505181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557199548, states[0] = -94.492022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567000145, states[0] = -94.493413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575186194, states[0] = -68.289490, states[40]= 0.000005
Saving checkpoint... 
Iteration: 584889810, states[0] = -94.490923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592904069, states[0] = -94.430033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600641332, states[0] = -94.504046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610095836, states[0] = 3.743818, states[40]= 0.004568
Saving checkpoint... 
Iteration: 619296960, states[0] = -94.495167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628886473, states[0] = -94.500413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638178630, states[0] = -94.506580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646506154, states[0] = -94.498596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654744270, states[0] = -94.491680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662917080, states[0] = -94.439314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673015344, states[0] = -94.483280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681562462, states[0] = -94.497806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689788306, states[0] = -94.491398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698325353, states[0] = -94.509680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707691854, states[0] = -75.301854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 716717738, states[0] = -94.495922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725070210, states[0] = 14.805830, states[40]= 0.003789
Saving checkpoint... 
Iteration: 732809386, states[0] = -94.313426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741482528, states[0] = -94.498866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750383093, states[0] = -94.412308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759239587, states[0] = -94.495657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767300656, states[0] = -94.491273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776632087, states[0] = -94.496862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785878587, states[0] = -94.509308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795160196, states[0] = -44.197667, states[40]= 0.000252
Saving checkpoint... 
Iteration: 803496733, states[0] = -94.507544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811684836, states[0] = -94.496220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820838831, states[0] = -94.509559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828808320, states[0] = -94.501586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837046984, states[0] = -94.492866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845436543, states[0] = -94.451228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853665469, states[0] = -94.504227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861742629, states[0] = -94.495552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869689702, states[0] = -94.491864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877460349, states[0] = -94.490367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885592524, states[0] = -94.498560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894350325, states[0] = -94.494461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903074193, states[0] = -94.495814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911819704, states[0] = -94.494739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920185246, states[0] = -67.243408, states[40]= 0.000006
Saving checkpoint... 
Iteration: 928950213, states[0] = -94.499209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937021739, states[0] = -94.492985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945760072, states[0] = -94.509080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954298799, states[0] = -94.494913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962955663, states[0] = -94.461078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970914237, states[0] = -94.508762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979027694, states[0] = -94.498063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987874788, states[0] = -94.404157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997195682, states[0] = -94.491736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005636911, states[0] = -94.503383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014804592, states[0] = -94.491077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023399412, states[0] = -94.508914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032069393, states[0] = -94.492564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040914817, states[0] = -94.508705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049404451, states[0] = -94.493864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057383062, states[0] = -94.490624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065371863, states[0] = -94.401139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074243836, states[0] = -94.495390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082331306, states[0] = -94.490881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090094140, states[0] = 4.600378, states[40]= 0.004576
Saving checkpoint... 
Iteration: 1098229429, states[0] = -94.508312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106404760, states[0] = -94.499784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114240594, states[0] = -94.495396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122398146, states[0] = -94.490501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131068443, states[0] = -94.505945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139708040, states[0] = -94.491558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147590560, states[0] = 6.338566, states[40]= 0.004552
Saving checkpoint... 
Iteration: 1155835377, states[0] = -94.509335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163241269, states[0] = -94.508565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173240951, states[0] = -94.508551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181833556, states[0] = -94.494416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189422565, states[0] = -94.493609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197455797, states[0] = -94.490164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205238253, states[0] = -94.123452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213641641, states[0] = -94.504441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223347766, states[0] = -94.509235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231212150, states[0] = -94.503061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239326449, states[0] = -94.494443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246639922, states[0] = -94.496437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255196351, states[0] = -81.898431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1264363073, states[0] = -94.494083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272002374, states[0] = -94.492899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279586506, states[0] = -94.492267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287253191, states[0] = -94.491181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295288173, states[0] = -94.268679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303631126, states[0] = -94.504585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312287203, states[0] = -94.490965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320607002, states[0] = -94.500097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329073068, states[0] = -94.497211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337940340, states[0] = -94.452992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346300844, states[0] = -94.501353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353766814, states[0] = -94.501958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361804412, states[0] = -94.494570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370092312, states[0] = 5.499210, states[40]= 0.004570
Saving checkpoint... 
Iteration: 1377889393, states[0] = -94.417520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386369785, states[0] = -94.500151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394302683, states[0] = -94.494564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402555599, states[0] = 19.648789, states[40]= 0.002905
Saving checkpoint... 
Iteration: 1410966556, states[0] = -94.507649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419804127, states[0] = -94.490794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428406414, states[0] = -94.508542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435422132, states[0] = -94.442102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444328071, states[0] = -94.494283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452848423, states[0] = -94.373895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461486255, states[0] = -94.498305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469778690, states[0] = -94.490903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478378594, states[0] = -94.508821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486448421, states[0] = -94.498843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495596131, states[0] = -94.498614, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.365718
 - CaMKt in component CaMK (millimolar): 0.001122
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.288681
 - nass in component intracellular_ions (millimolar): 6.288767
 - ki in component intracellular_ions (millimolar): 145.637289
 - kss in component intracellular_ions (millimolar): 145.637279
 - cansr in component intracellular_ions (millimolar): 1.562904
 - cajsr in component intracellular_ions (millimolar): 1.562947
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003820
 - hf in component INa (dimensionless): 0.870381
 - hs in component INa (dimensionless): 0.870381
 - j in component INa (dimensionless): 0.870382
 - hsp in component INa (dimensionless): 0.707982
 - jp in component INa (dimensionless): 0.870382
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.714805
 - hLp in component INaL (dimensionless): 0.522622
 - a in component Ito (dimensionless): 0.000646
 - iF in component Ito (dimensionless): 0.999857
 - iS in component Ito (dimensionless): 0.997753
 - ap in component Ito (dimensionless): 0.000329
 - iFp in component Ito (dimensionless): 0.999857
 - iSp in component Ito (dimensionless): 0.999257
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998849
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002969
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001781
 - xs1 in component IKs (dimensionless): 0.023016
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997474
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:04:17 (54779): called boinc_finish(0)

</stderr_txt>
]]>


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