𝕏

Task 55578233

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_6000-conf_578_0
Workunit 26390123
Created 1 Jul 2024, 15:22:00 UTC
Sent 1 Jul 2024, 23:16:50 UTC
Report deadline 4 Jul 2024, 23:16:50 UTC
Received 2 Jul 2024, 3:39:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236572
Run time 2 hours 19 min 37 sec
CPU time 1 hours 7 min 19 sec
Validate state Valid
Credit 46.28
Device peak FLOPS 4.75 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.11 MB
Peak swap size 5.31 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_6000-conf_578.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_6000-conf_578_0_r1402476386_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_6000-conf_578_0_r1402476386_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.125634
     * GNaL_b in INaL: 0.005513
     * Gto_b in Ito: 0.084287
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031666
     * GKs_b in IKs: 0.001944
     * GK1_b in IK1: 0.163517
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.287109
     * GKb_b in IKb: 0.003818
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037185
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11730371, states[0] = -94.191080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19891178, states[0] = -94.181674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28258881, states[0] = -94.195640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36309402, states[0] = -79.840393, states[40]= 0.000006
Saving checkpoint... 
Iteration: 44537742, states[0] = -94.186944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 52552997, states[0] = -94.204753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 60697671, states[0] = -94.219838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68810501, states[0] = -94.201350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77304365, states[0] = -94.208053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85533164, states[0] = -94.222011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93795212, states[0] = -94.240975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102177252, states[0] = -15.544275, states[40]= 0.000864
Saving checkpoint... 
Iteration: 110186311, states[0] = -94.219488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 118462815, states[0] = -94.232162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 126582431, states[0] = -94.217751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134631504, states[0] = -94.220663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 142836112, states[0] = -94.228301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 150901120, states[0] = -94.250909, states[40]= 0.000001
Saving checkpoint... 
Iteration: 159044548, states[0] = 33.198818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167202332, states[0] = -94.225856, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175338782, states[0] = -94.240441, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183544272, states[0] = -94.206315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191600923, states[0] = -94.224240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 199745813, states[0] = -94.232397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208006440, states[0] = -94.250836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 216204085, states[0] = -25.488676, states[40]= 0.005394
Saving checkpoint... 
Iteration: 224558153, states[0] = -94.224897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 232798354, states[0] = -94.231900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 240727056, states[0] = -94.249623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 248648396, states[0] = -94.224596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 256745265, states[0] = -94.232770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265215891, states[0] = -94.244906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273551043, states[0] = -94.210432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281678440, states[0] = -94.224427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 289935520, states[0] = -94.229943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298089867, states[0] = -94.248565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 306375396, states[0] = -93.996587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314712200, states[0] = -94.224158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 323022194, states[0] = -94.228754, states[40]= 0.000001
Saving checkpoint... 
Iteration: 331324168, states[0] = -94.241541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 339562026, states[0] = -94.214988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347821060, states[0] = -94.223643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 356158541, states[0] = -94.227187, states[40]= 0.000001
Saving checkpoint... 
Iteration: 364387488, states[0] = -94.239675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 372832946, states[0] = -94.252906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 380949616, states[0] = -94.223149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 389105968, states[0] = -94.227471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 397218631, states[0] = -94.244118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 405309370, states[0] = -93.753927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413538486, states[0] = -94.224247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421667370, states[0] = -94.233232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429883627, states[0] = -94.252481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 438325866, states[0] = -93.829386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445934141, states[0] = -94.229011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 454164411, states[0] = -94.245355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462387379, states[0] = -94.024700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470607149, states[0] = -94.223558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 478904969, states[0] = -94.229165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487075954, states[0] = -94.247787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495350683, states[0] = -93.922775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503571260, states[0] = -94.223493, states[40]= 0.000001
Saving checkpoint... 
Iteration: 512133250, states[0] = -94.226389, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520294679, states[0] = -94.241116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528468627, states[0] = -94.150768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536900422, states[0] = -94.222206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545222372, states[0] = -94.225383, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553969757, states[0] = -94.227848, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562314781, states[0] = -94.240279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 570482708, states[0] = -94.163879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578560585, states[0] = -94.223037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 586717459, states[0] = -94.231247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595054807, states[0] = -94.247679, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603189422, states[0] = -21.258136, states[40]= 0.003219
Saving checkpoint... 
Iteration: 611247039, states[0] = -94.224741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 619464975, states[0] = -94.236086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627621844, states[0] = -94.232245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 635620582, states[0] = -94.222393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643959484, states[0] = -94.227367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651893533, states[0] = -94.250897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 660137403, states[0] = 2.551593, states[40]= 0.000162
Saving checkpoint... 
Iteration: 668172759, states[0] = -94.224979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676474033, states[0] = -94.235492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 684626940, states[0] = -94.233037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692703765, states[0] = -94.221697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 700688376, states[0] = -94.230983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 708897714, states[0] = -94.250467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717105887, states[0] = 14.039584, states[40]= 0.000013
Saving checkpoint... 
Iteration: 725243827, states[0] = -94.223998, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733272282, states[0] = -94.240313, states[40]= 0.000001
Saving checkpoint... 
Iteration: 741413436, states[0] = -94.074955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749517089, states[0] = -94.222093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 757744232, states[0] = -94.229650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 765916203, states[0] = -94.249832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 774172342, states[0] = -14.122197, states[40]= 0.000660
Saving checkpoint... 
Iteration: 782287322, states[0] = -94.223281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790574194, states[0] = -94.232547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 798947448, states[0] = -94.249046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807130280, states[0] = 5.189785, states[40]= 0.000098
Saving checkpoint... 
Iteration: 815288909, states[0] = -94.223047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 823384656, states[0] = -94.236675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831465267, states[0] = -94.145241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839991442, states[0] = -94.219995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 848010324, states[0] = -94.225397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 856459275, states[0] = -94.234624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864563613, states[0] = -94.212143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872800785, states[0] = -94.220185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 880968974, states[0] = -94.225656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 889273038, states[0] = -94.239243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897650075, states[0] = -94.236251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 905778068, states[0] = -94.220027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 914276123, states[0] = -94.222476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 922652992, states[0] = -94.230128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930818628, states[0] = -94.249020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 939021550, states[0] = 33.288955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947272793, states[0] = -94.222279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 955587355, states[0] = -94.231171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 964026852, states[0] = -94.245989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972204530, states[0] = -25.696458, states[40]= 0.005397
Saving checkpoint... 
Iteration: 980405185, states[0] = -94.221155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 989099780, states[0] = -94.223501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997313752, states[0] = -94.237382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005773406, states[0] = -94.247388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013922862, states[0] = -94.218947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1022185859, states[0] = -94.222480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1030501759, states[0] = -94.232481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038626068, states[0] = -94.230458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046868618, states[0] = -94.218841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1055148483, states[0] = -94.222592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1063574524, states[0] = -94.230704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071736369, states[0] = -94.245044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1079932198, states[0] = -94.218484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1088196883, states[0] = -94.221940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1096399689, states[0] = -94.234458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104730645, states[0] = -94.244429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1113216904, states[0] = -30.574472, states[40]= 0.004716
Saving checkpoint... 
Iteration: 1121678623, states[0] = -94.218896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1129925192, states[0] = -94.224522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137976359, states[0] = -94.246127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146264195, states[0] = -63.939299, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1154541877, states[0] = -94.219244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1162708538, states[0] = -94.227523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1171336985, states[0] = -94.235582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1179539728, states[0] = -94.198924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187861967, states[0] = -94.217907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195983009, states[0] = -94.223369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1204291475, states[0] = -94.236606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1213143715, states[0] = -94.240878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221465410, states[0] = -94.142749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229670851, states[0] = -94.218197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1237972310, states[0] = -94.223213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246134268, states[0] = -94.240942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254420587, states[0] = -94.083531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262836894, states[0] = -94.217463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271300094, states[0] = -94.219894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1279464850, states[0] = -94.231649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287817616, states[0] = -94.246607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1296432380, states[0] = -94.101368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304456165, states[0] = -94.218676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1312497490, states[0] = -94.230679, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320677300, states[0] = -94.237631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1328739544, states[0] = -94.217295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1336768395, states[0] = -94.225365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1345175707, states[0] = -94.239028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1353718072, states[0] = -94.241783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361666646, states[0] = -94.217323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1370338468, states[0] = -94.218958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1378604656, states[0] = -94.227980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387217050, states[0] = -94.237515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395158801, states[0] = -6.686650, states[40]= 0.000463
Saving checkpoint... 
Iteration: 1403350270, states[0] = -94.218656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411283346, states[0] = -94.235442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419862301, states[0] = -94.245951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427700653, states[0] = -94.216756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435959104, states[0] = -94.222039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444054969, states[0] = -94.241968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1452152158, states[0] = -3.471895, states[40]= 0.000372
Saving checkpoint... 
Iteration: 1460449024, states[0] = -94.217665, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1468829350, states[0] = -94.223548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1476918700, states[0] = -94.245015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484998814, states[0] = -94.215638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1493066137, states[0] = -94.220449, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.091515
 - CaMKt in component CaMK (millimolar): 0.001347
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.744529
 - nass in component intracellular_ions (millimolar): 7.744677
 - ki in component intracellular_ions (millimolar): 144.094562
 - kss in component intracellular_ions (millimolar): 144.094549
 - cansr in component intracellular_ions (millimolar): 1.760381
 - cajsr in component intracellular_ions (millimolar): 1.761614
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003927
 - hf in component INa (dimensionless): 0.865212
 - hs in component INa (dimensionless): 0.865212
 - j in component INa (dimensionless): 0.865213
 - hsp in component INa (dimensionless): 0.698580
 - jp in component INa (dimensionless): 0.865213
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707273
 - hLp in component INaL (dimensionless): 0.513538
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999138
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999681
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999274
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004195
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000645
 - xs1 in component IKs (dimensionless): 0.019693
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997542
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:59:42 (5620): called boinc_finish(0)

</stderr_txt>
]]>


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