𝕏

Task 55574746

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_5000-conf_775_0
Workunit 26388386
Created 1 Jul 2024, 15:20:24 UTC
Sent 1 Jul 2024, 23:06:38 UTC
Report deadline 4 Jul 2024, 23:06:38 UTC
Received 2 Jul 2024, 23:05:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232190
Run time 2 hours 19 min 58 sec
CPU time 2 hours 17 min 20 sec
Validate state Valid
Credit 49.25
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.69 MB
Peak swap size 4.08 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_5000-conf_775.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_5000-conf_775_0_r901305599_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_5000-conf_775_0_r901305599_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.197839
     * GNaL_b in INaL: 0.005696
     * Gto_b in Ito: 0.081320
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031906
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.160033
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.363500
     * GKb_b in IKb: 0.003819
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033307
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11036649, states[0] = -94.033848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22105825, states[0] = -93.932231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33177474, states[0] = -93.924847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44226699, states[0] = -93.884866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55293921, states[0] = -93.565331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66338865, states[0] = -93.884886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77396037, states[0] = -93.863571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88467178, states[0] = -93.896478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99487837, states[0] = -93.867367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110524230, states[0] = -93.870139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121540281, states[0] = -93.875803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132592932, states[0] = 7.890222, states[40]= 0.003034
Saving checkpoint... 
Iteration: 143618010, states[0] = -93.889300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154647245, states[0] = -93.864242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165703625, states[0] = -93.898821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176728447, states[0] = -93.870994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187770472, states[0] = -93.465814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198788534, states[0] = -93.882716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209772946, states[0] = -93.862461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220791577, states[0] = -93.899724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231819703, states[0] = -93.869027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242866159, states[0] = -93.733135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253893079, states[0] = -93.879200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264947616, states[0] = -93.860497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275974592, states[0] = -93.894472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287022789, states[0] = -93.865535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298086435, states[0] = -93.886157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309090261, states[0] = -93.873728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320124427, states[0] = -11.906076, states[40]= 0.002269
Saving checkpoint... 
Iteration: 331175413, states[0] = -93.886483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342246236, states[0] = -93.862480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353275680, states[0] = -93.899530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364334775, states[0] = -93.868479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375381622, states[0] = -93.756935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386410546, states[0] = -93.878414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397459125, states[0] = -93.860130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408497603, states[0] = -93.893324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419522886, states[0] = -93.865281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430586444, states[0] = -93.885908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441594416, states[0] = -93.873378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452638592, states[0] = -23.168186, states[40]= 0.002272
Saving checkpoint... 
Iteration: 463704472, states[0] = -93.885149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474761334, states[0] = -93.862055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485773841, states[0] = -93.899286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496817365, states[0] = -93.868551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507812352, states[0] = -93.613296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518823973, states[0] = -93.880876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529832618, states[0] = -93.861159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540860072, states[0] = -93.897840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551909596, states[0] = -93.866819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562962060, states[0] = -93.837329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573985033, states[0] = -93.875937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585047221, states[0] = 25.637991, states[40]= 0.000358
Saving checkpoint... 
Iteration: 596127234, states[0] = -93.887838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607202210, states[0] = -93.862511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618218226, states[0] = -93.898338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629220646, states[0] = -93.870204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640264767, states[0] = -93.440019, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_5000-conf_775.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_5000-conf_775_0_r901305599_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_5000-conf_775_0_r901305599_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.197839
     * GNaL_b in INaL: 0.005696
     * Gto_b in Ito: 0.081320
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031906
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.160033
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.363500
     * GKb_b in IKb: 0.003819
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033307
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 640264767
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.440019 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 651616321, states[0] = -93.872465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662884733, states[0] = -93.760812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674197528, states[0] = -93.870606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685499490, states[0] = -93.858123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696829434, states[0] = -93.867954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708154925, states[0] = -93.894678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719468698, states[0] = -93.865546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730750029, states[0] = -93.898732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742079400, states[0] = -93.863865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753412035, states[0] = -93.895856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764714249, states[0] = -93.862069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776018343, states[0] = -93.891820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787315617, states[0] = -93.860861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798614807, states[0] = -93.887946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809923496, states[0] = -93.859702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821216096, states[0] = -93.884055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832543217, states[0] = 26.896594, states[40]= 0.000286
Saving checkpoint... 
Iteration: 843876978, states[0] = -93.878579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855190793, states[0] = -63.168074, states[40]= 0.000030
Saving checkpoint... 
Iteration: 866505726, states[0] = -93.874831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877841087, states[0] = -93.684196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889140398, states[0] = -93.871464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900453734, states[0] = -93.830914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911774935, states[0] = -93.868583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923103774, states[0] = -93.888073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934424970, states[0] = -93.865848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945735119, states[0] = -93.898123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957022600, states[0] = -93.864279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968328154, states[0] = -93.897781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979609151, states[0] = -93.863012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990905324, states[0] = -93.895639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002159973, states[0] = -93.862301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013446258, states[0] = -93.894157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024751151, states[0] = -93.861144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036049631, states[0] = -93.890089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047347899, states[0] = -93.860027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058618888, states[0] = -93.887301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069914086, states[0] = -93.859308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081220087, states[0] = -93.883423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092486186, states[0] = -93.858576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103795542, states[0] = -93.880730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115107343, states[0] = 0.354922, states[40]= 0.003914
Saving checkpoint... 
Iteration: 1126419891, states[0] = -93.876754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137686888, states[0] = -59.963008, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1148969163, states[0] = -93.875300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160255381, states[0] = -93.395824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171552180, states[0] = -93.873054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182854163, states[0] = -93.709986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194164062, states[0] = -93.870362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205486821, states[0] = -93.850858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216797268, states[0] = -93.867582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228090454, states[0] = -93.885187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239418488, states[0] = -93.865384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250712110, states[0] = -93.896968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262057312, states[0] = -93.863203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273359147, states[0] = -93.896498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284662081, states[0] = -93.861745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295953585, states[0] = -93.893358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307279447, states[0] = -93.860290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318582349, states[0] = -93.888258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329915937, states[0] = -93.858803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341253400, states[0] = -93.881743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352538261, states[0] = 28.346939, states[40]= 0.000219
Saving checkpoint... 
Iteration: 1363839925, states[0] = -93.878778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375122270, states[0] = -10.154428, states[40]= 0.002582
Saving checkpoint... 
Iteration: 1386411696, states[0] = -93.876511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397733776, states[0] = -93.253778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409058075, states[0] = -93.872461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420397880, states[0] = -93.776657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431745129, states[0] = -93.868202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443037621, states[0] = -93.871604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454006193, states[0] = -93.873720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464904188, states[0] = -93.858667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476218042, states[0] = -93.882760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487515925, states[0] = 31.845345, states[40]= 0.007548
Saving checkpoint... 
Iteration: 1498847137, states[0] = -93.878294, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.733661
 - CaMKt in component CaMK (millimolar): 0.001579
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.707146
 - nass in component intracellular_ions (millimolar): 6.707270
 - ki in component intracellular_ions (millimolar): 145.155208
 - kss in component intracellular_ions (millimolar): 145.155198
 - cansr in component intracellular_ions (millimolar): 1.833462
 - cajsr in component intracellular_ions (millimolar): 1.833321
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004071
 - hf in component INa (dimensionless): 0.858207
 - hs in component INa (dimensionless): 0.858207
 - j in component INa (dimensionless): 0.858209
 - hsp in component INa (dimensionless): 0.686058
 - jp in component INa (dimensionless): 0.858211
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.697305
 - hLp in component INaL (dimensionless): 0.501593
 - a in component Ito (dimensionless): 0.000675
 - iF in component Ito (dimensionless): 0.999840
 - iS in component Ito (dimensionless): 0.997548
 - ap in component Ito (dimensionless): 0.000344
 - iFp in component Ito (dimensionless): 0.999840
 - iSp in component Ito (dimensionless): 0.999147
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998705
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005413
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002214
 - xs1 in component IKs (dimensionless): 0.024349
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997627
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:22:38 (75272): called boinc_finish(0)

</stderr_txt>
]]>


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