𝕏

Task 55568682

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_169_0
Workunit 26385359
Created 1 Jul 2024, 15:17:35 UTC
Sent 1 Jul 2024, 22:45:37 UTC
Report deadline 4 Jul 2024, 22:45:37 UTC
Received 2 Jul 2024, 23:08:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 225785
Run time 1 hours 44 min 30 sec
CPU time 1 hours 34 min 31 sec
Validate state Valid
Credit 41.80
Device peak FLOPS 3.23 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.57 MB
Peak swap size 5.27 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_169.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_169_0_r476688574_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_169_0_r476688574_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.599039
     * GNaL_b in INaL: 0.006172
     * Gto_b in Ito: 0.083917
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031604
     * GKs_b in IKs: 0.001898
     * GK1_b in IK1: 0.166274
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.632494
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033541
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9038926, states[0] = 14.637315, states[40]= 0.005016
Saving checkpoint... 
Iteration: 17444851, states[0] = -87.089790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27340603, states[0] = -87.019354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36947910, states[0] = -87.032470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46291685, states[0] = -86.945802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55596200, states[0] = -18.036522, states[40]= 0.001087
Saving checkpoint... 
Iteration: 63766041, states[0] = -86.900284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71939285, states[0] = -86.989263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81641519, states[0] = -65.412970, states[40]= 0.000002
Saving checkpoint... 
Iteration: 90998841, states[0] = -86.989521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100574539, states[0] = 0.590520, states[40]= 0.004221
Saving checkpoint... 
Iteration: 108542456, states[0] = 14.983613, states[40]= 0.004864
Saving checkpoint... 
Iteration: 118183888, states[0] = -86.740639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127263755, states[0] = -86.873815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135182224, states[0] = -86.734350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144759666, states[0] = -86.867170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154560304, states[0] = 7.772261, states[40]= 0.004694
Saving checkpoint... 
Iteration: 162691274, states[0] = -86.752406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172388553, states[0] = -86.954716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180771659, states[0] = -86.879283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190777646, states[0] = -86.885357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198920523, states[0] = -86.963595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208789149, states[0] = -86.896181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217197795, states[0] = -86.764239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226764241, states[0] = -86.870216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236156688, states[0] = -83.688374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244251266, states[0] = -86.853927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254356200, states[0] = -86.940512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262508995, states[0] = 23.660848, states[40]= 0.058652
Saving checkpoint... 
Iteration: 271979645, states[0] = -86.974564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280111119, states[0] = -31.285183, states[40]= 0.000373
Saving checkpoint... 
Iteration: 289904702, states[0] = -86.958687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298624167, states[0] = -44.502284, states[40]= 0.000060
Saving checkpoint... 
Iteration: 308398972, states[0] = -86.956915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316649038, states[0] = -74.744683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326206310, states[0] = -86.780470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335600505, states[0] = -20.731773, states[40]= 0.000874
Saving checkpoint... 
Iteration: 345024946, states[0] = 20.957446, states[40]= 0.006416
Saving checkpoint... 
Iteration: 353348220, states[0] = -86.936434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362677091, states[0] = -86.712895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370689713, states[0] = -86.747551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380393323, states[0] = -86.955031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389750586, states[0] = -86.852776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398735717, states[0] = -86.831428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407941382, states[0] = -86.967735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417155897, states[0] = -83.075680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426572752, states[0] = 1.796378, states[40]= 0.004343
Saving checkpoint... 
Iteration: 435835559, states[0] = -86.929514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445186454, states[0] = -86.740633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454624127, states[0] = -44.458623, states[40]= 0.000060
Saving checkpoint... 
Iteration: 461209574, states[0] = -86.786558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470617644, states[0] = -37.806528, states[40]= 0.000161
Saving checkpoint... 
Iteration: 479802956, states[0] = -86.907349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489666569, states[0] = -86.491462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498978794, states[0] = -86.974221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506611998, states[0] = -32.157410, states[40]= 0.000338
Saving checkpoint... 
Iteration: 515960708, states[0] = -86.971338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525207600, states[0] = -86.782780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534550168, states[0] = 12.040196, states[40]= 0.004767
Saving checkpoint... 
Iteration: 544073824, states[0] = 1.206982, states[40]= 0.004283
Saving checkpoint... 
Iteration: 553345168, states[0] = -86.934714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562758080, states[0] = -86.862315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571909197, states[0] = -86.959758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581241714, states[0] = -86.840266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590477743, states[0] = -86.974005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599902104, states[0] = -86.957657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609381874, states[0] = -86.950878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618849214, states[0] = -86.936749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628213773, states[0] = -86.794239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637566084, states[0] = 5.170688, states[40]= 0.004592
Saving checkpoint... 
Iteration: 647096250, states[0] = -16.500474, states[40]= 0.001241
Saving checkpoint... 
Iteration: 656351882, states[0] = -86.938051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665671002, states[0] = -86.651783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675386287, states[0] = -86.952423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685124567, states[0] = -44.919946, states[40]= 0.000056
Saving checkpoint... 
Iteration: 694821752, states[0] = -86.920821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704118359, states[0] = -38.528381, states[40]= 0.000146
Saving checkpoint... 
Iteration: 712431092, states[0] = -86.965268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721910318, states[0] = -86.959971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731100711, states[0] = -20.936040, states[40]= 0.000861
Saving checkpoint... 
Iteration: 739883043, states[0] = -86.951216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749110630, states[0] = -30.795786, states[40]= 0.000393
Saving checkpoint... 
Iteration: 758565765, states[0] = 5.321909, states[40]= 0.004600
Saving checkpoint... 
Iteration: 768227099, states[0] = -86.817412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777299076, states[0] = -86.904001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786608595, states[0] = -28.772415, states[40]= 0.000482
Saving checkpoint... 
Iteration: 795894038, states[0] = -86.954977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805154868, states[0] = -82.158847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814354973, states[0] = -86.939438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822404210, states[0] = -86.958137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832149235, states[0] = -75.027951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839999450, states[0] = -86.976694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848250101, states[0] = -86.851807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857767536, states[0] = -86.873328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866127400, states[0] = -47.926730, states[40]= 0.000035
Saving checkpoint... 
Iteration: 875549012, states[0] = 12.503344, states[40]= 0.004775
Saving checkpoint... 
Iteration: 885241604, states[0] = -86.839895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893938023, states[0] = -86.966687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903367505, states[0] = -86.945004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912562760, states[0] = 6.710469, states[40]= 0.004660
Saving checkpoint... 
Iteration: 922232671, states[0] = -86.826319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931608021, states[0] = -28.201841, states[40]= 0.000508
Saving checkpoint... 
Iteration: 940980710, states[0] = -86.974192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950084764, states[0] = -6.019069, states[40]= 0.003112
Saving checkpoint... 
Iteration: 959042096, states[0] = 15.209107, states[40]= 0.004872
Saving checkpoint... 
Iteration: 968315317, states[0] = -86.916252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977384920, states[0] = -86.951730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986390205, states[0] = -86.953567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995611396, states[0] = -31.557702, states[40]= 0.000362
Saving checkpoint... 
Iteration: 1005140396, states[0] = -62.798104, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1014461293, states[0] = -86.971097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023765059, states[0] = -86.870376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032962723, states[0] = -86.971329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042602436, states[0] = -22.652156, states[40]= 0.000766
Saving checkpoint... 
Iteration: 1052093124, states[0] = -13.439393, states[40]= 0.001661
Saving checkpoint... 
Iteration: 1061555142, states[0] = 10.006849, states[40]= 0.004738
Saving checkpoint... 
Iteration: 1070569352, states[0] = 3.572979, states[40]= 0.004493
Saving checkpoint... 
Iteration: 1079976591, states[0] = -86.973499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089299768, states[0] = -86.904355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098449504, states[0] = -86.968889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107798402, states[0] = -86.903214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116945435, states[0] = -86.968076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125900723, states[0] = -86.956873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135098728, states[0] = -18.961255, states[40]= 0.001001
Saving checkpoint... 
Iteration: 1144414979, states[0] = -86.960961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153849590, states[0] = -86.936570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163006409, states[0] = 24.949231, states[40]= 0.108423
Saving checkpoint... 
Iteration: 1172110105, states[0] = -30.273242, states[40]= 0.000416
Saving checkpoint... 
Iteration: 1181604418, states[0] = -24.622062, states[40]= 0.000671
Saving checkpoint... 
Iteration: 1190996684, states[0] = -86.976122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200295896, states[0] = -86.901041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209363621, states[0] = -86.943122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218761963, states[0] = -86.866595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228151145, states[0] = -77.734172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237371807, states[0] = -86.946555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245486922, states[0] = -86.974841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253329547, states[0] = -86.925384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262975336, states[0] = -86.973186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271902329, states[0] = -86.957263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279917960, states[0] = -86.961657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289343785, states[0] = -86.933477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298772977, states[0] = -86.879017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306823413, states[0] = -86.921486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316117346, states[0] = -37.505371, states[40]= 0.000168
Saving checkpoint... 
Iteration: 1324304121, states[0] = -86.907686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332409660, states[0] = -86.959366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340686245, states[0] = -86.739554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349979403, states[0] = -86.973724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359362339, states[0] = -86.942453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368828032, states[0] = -86.924373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377963196, states[0] = -86.971172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387379394, states[0] = -86.949419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396390879, states[0] = -86.953513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405743175, states[0] = -86.841805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415131310, states[0] = -52.180582, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1424416209, states[0] = -86.961097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433501941, states[0] = 39.110368, states[40]= 0.111905
Saving checkpoint... 
Iteration: 1442660501, states[0] = -85.548812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451899573, states[0] = -86.956294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461047691, states[0] = 13.028853, states[40]= 0.004786
Saving checkpoint... 
Iteration: 1470191699, states[0] = -86.750841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479722818, states[0] = -86.809701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489004193, states[0] = 28.621782, states[40]= 0.157682
Saving checkpoint... 
Iteration: 1498463929, states[0] = -86.971213, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.852182
 - CaMKt in component CaMK (millimolar): 0.006727
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.402162
 - nass in component intracellular_ions (millimolar): 6.402220
 - ki in component intracellular_ions (millimolar): 145.582486
 - kss in component intracellular_ions (millimolar): 145.582467
 - cansr in component intracellular_ions (millimolar): 1.290518
 - cajsr in component intracellular_ions (millimolar): 1.252701
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008142
 - hf in component INa (dimensionless): 0.661455
 - hs in component INa (dimensionless): 0.661443
 - j in component INa (dimensionless): 0.661381
 - hsp in component INa (dimensionless): 0.413599
 - jp in component INa (dimensionless): 0.661338
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.466383
 - hLp in component INaL (dimensionless): 0.240838
 - a in component Ito (dimensionless): 0.001073
 - iF in component Ito (dimensionless): 0.999467
 - iS in component Ito (dimensionless): 0.577658
 - ap in component Ito (dimensionless): 0.000547
 - iFp in component Ito (dimensionless): 0.999467
 - iSp in component Ito (dimensionless): 0.631903
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934279
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001515
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.410535
 - xs1 in component IKs (dimensionless): 0.244180
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997018
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:53:38 (9844): called boinc_finish(0)

</stderr_txt>
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