𝕏

Task 55567505

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_10000-conf_368_0
Workunit 26384771
Created 1 Jul 2024, 15:17:04 UTC
Sent 1 Jul 2024, 22:35:29 UTC
Report deadline 4 Jul 2024, 22:35:29 UTC
Received 2 Jul 2024, 11:56:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241293
Run time 1 hours 48 min 20 sec
CPU time 1 hours 46 min 16 sec
Validate state Valid
Credit 43.55
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.41 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_10000-conf_368.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_10000-conf_368_0_r1327988071_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_10000-conf_368_0_r1327988071_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.566420
     * GNaL_b in INaL: 0.005520
     * Gto_b in Ito: 0.084399
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031804
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.163445
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.140392
     * GKb_b in IKb: 0.003793
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031208
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8680054, states[0] = -94.194539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17100838, states[0] = -94.174864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25458032, states[0] = -63.550353, states[40]= 0.000064
Saving checkpoint... 
Iteration: 33724463, states[0] = -94.149637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 42027695, states[0] = -94.170243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50256316, states[0] = -34.502792, states[40]= 0.003994
Saving checkpoint... 
Iteration: 58572042, states[0] = -94.176621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67515332, states[0] = -94.184659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 76525928, states[0] = -94.201098, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85162047, states[0] = -4.764278, states[40]= 0.000383
Saving checkpoint... 
Iteration: 93705456, states[0] = -94.191445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102120499, states[0] = -94.199341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 111037829, states[0] = -94.223219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 119591596, states[0] = -94.197268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128065311, states[0] = -94.198428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 136600474, states[0] = -94.211940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 145348875, states[0] = -93.875695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154080660, states[0] = -94.200231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162519922, states[0] = -94.203181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 171034052, states[0] = -94.228642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179385639, states[0] = -94.201650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187740695, states[0] = -94.203044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 195790047, states[0] = -94.230963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203911224, states[0] = -94.201871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 212212095, states[0] = -94.206712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220565278, states[0] = -94.192858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229219119, states[0] = -94.202346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238025749, states[0] = -94.202826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 246255022, states[0] = -94.223520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255089758, states[0] = 20.596564, states[40]= 0.000002
Saving checkpoint... 
Iteration: 263755753, states[0] = -94.202229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 272181811, states[0] = -94.207260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 280509826, states[0] = -94.162092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289095111, states[0] = -94.202368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297494379, states[0] = -94.204930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 305986944, states[0] = -94.230944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 314171025, states[0] = -94.202381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322214341, states[0] = -94.206895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330992360, states[0] = -94.230761, states[40]= 0.000001
Saving checkpoint... 
Iteration: 339266018, states[0] = -94.202397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347876893, states[0] = -94.203150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 356435435, states[0] = -94.218697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365271721, states[0] = -61.623950, states[40]= 0.000071
Saving checkpoint... 
Iteration: 373869063, states[0] = -94.202037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 382043032, states[0] = -94.208408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390500192, states[0] = -94.154617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399143815, states[0] = -94.202108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407768007, states[0] = -94.203326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 416309251, states[0] = -94.221698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425012191, states[0] = 30.417350, states[40]= 0.000002
Saving checkpoint... 
Iteration: 432962454, states[0] = -94.202630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441383056, states[0] = -94.219694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 449987551, states[0] = -94.202898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457692918, states[0] = -94.203453, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465597448, states[0] = -94.204416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473986713, states[0] = -94.201749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482402113, states[0] = -94.204934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 490735583, states[0] = -94.228025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499040606, states[0] = -94.201693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 500490539, states[0] = -94.146317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509194287, states[0] = -94.201768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517415438, states[0] = -94.204724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 525666250, states[0] = -94.220063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534124202, states[0] = -94.201627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542050874, states[0] = -94.207772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 550072782, states[0] = 26.369848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558317096, states[0] = -94.201564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 566466954, states[0] = -94.217245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574398172, states[0] = -94.201730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582745297, states[0] = -94.202805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 590956576, states[0] = -94.230646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 599091148, states[0] = -94.201376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 607078308, states[0] = -94.207249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 615322711, states[0] = -93.778127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624374445, states[0] = -94.201531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632738908, states[0] = -94.202655, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641542804, states[0] = -94.215317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 649674365, states[0] = -94.201784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657903423, states[0] = -94.202008, states[40]= 0.000001
Saving checkpoint... 
Iteration: 665739652, states[0] = -94.227708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674465675, states[0] = -94.201452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682734661, states[0] = -94.202497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 690947250, states[0] = -94.230470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699500055, states[0] = -94.201402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708351989, states[0] = -94.201004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 716712854, states[0] = -94.211828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 724898768, states[0] = -94.201815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733325747, states[0] = -94.200942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 741683813, states[0] = -94.212245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750091849, states[0] = 19.856512, states[40]= 0.000002
Saving checkpoint... 
Iteration: 758150879, states[0] = -94.201094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 766249720, states[0] = -94.222116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773858527, states[0] = -94.200646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 782155131, states[0] = -94.205868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790603369, states[0] = -94.205097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799020462, states[0] = -94.200631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807777675, states[0] = -94.201896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 816122265, states[0] = -94.225607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 824993897, states[0] = -94.201596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833192385, states[0] = -94.200764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841235181, states[0] = -94.222264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849583957, states[0] = -94.200974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857570480, states[0] = -94.202630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865904459, states[0] = -94.230467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874042542, states[0] = -94.200382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 882510098, states[0] = -94.202870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890917326, states[0] = -94.230233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898406889, states[0] = -94.200291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 906838157, states[0] = -94.209190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 915489648, states[0] = -94.144090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924045569, states[0] = -94.200209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932617168, states[0] = -94.202135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940256518, states[0] = -49.462646, states[40]= 0.000469
Saving checkpoint... 
Iteration: 948926410, states[0] = -94.200059, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957602263, states[0] = -94.202120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 966230268, states[0] = -94.221967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975019079, states[0] = 32.918145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983785088, states[0] = -94.199893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 992549044, states[0] = -94.202270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000455679, states[0] = -94.109043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008713576, states[0] = -94.199798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1017123887, states[0] = -94.205349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025792671, states[0] = -94.229073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034163229, states[0] = -94.199906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042755463, states[0] = -94.201156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1050923121, states[0] = -94.229598, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1059411413, states[0] = -94.200046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067751448, states[0] = -94.201084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1075992592, states[0] = -94.228187, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084540029, states[0] = -94.200100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092829457, states[0] = -94.200717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1101490935, states[0] = -94.214834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1110204899, states[0] = -23.255274, states[40]= 0.004659
Saving checkpoint... 
Iteration: 1118972506, states[0] = -94.199485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127093526, states[0] = -94.205272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1135890370, states[0] = -94.229644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144522040, states[0] = -94.199870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153300947, states[0] = -94.199500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161986606, states[0] = -94.206339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170346752, states[0] = -93.872164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179312438, states[0] = -94.199528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187093248, states[0] = -94.205065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195511618, states[0] = -94.160291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204186324, states[0] = -94.199330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212976591, states[0] = -94.199868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221126743, states[0] = -94.224064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1229404158, states[0] = -94.199444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237874134, states[0] = -94.200067, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246007454, states[0] = -94.227240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254682178, states[0] = -94.199676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262998641, states[0] = -94.199639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271376231, states[0] = -94.216969, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1279269716, states[0] = -94.199138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287421880, states[0] = -94.201989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1295717402, states[0] = -94.223713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304103356, states[0] = -94.198917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1312435213, states[0] = -94.201816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321186896, states[0] = -94.221971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1329858777, states[0] = -94.199643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338649054, states[0] = -94.198646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1346903258, states[0] = -94.206745, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1355627128, states[0] = -94.209459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364047255, states[0] = -94.198670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372343828, states[0] = -94.202229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380967639, states[0] = -94.227670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1389276568, states[0] = -94.198760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397917949, states[0] = -94.199377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1406486167, states[0] = -94.213875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414886622, states[0] = -94.199383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423154733, states[0] = -94.198760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1431153665, states[0] = -94.222551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439798314, states[0] = -94.199177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448678692, states[0] = -94.198259, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1456637437, states[0] = -94.210590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1465376232, states[0] = -93.962383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473964607, states[0] = -94.198239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483064369, states[0] = -94.198721, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1491737632, states[0] = -94.208703, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.075230
 - CaMKt in component CaMK (millimolar): 0.000843
 - cass in component intracellular_ions (millimolar): 0.000092
 - nai in component intracellular_ions (millimolar): 7.588259
 - nass in component intracellular_ions (millimolar): 7.588397
 - ki in component intracellular_ions (millimolar): 144.289753
 - kss in component intracellular_ions (millimolar): 144.289742
 - cansr in component intracellular_ions (millimolar): 1.691717
 - cajsr in component intracellular_ions (millimolar): 1.692408
 - cai in component intracellular_ions (millimolar): 0.000097
 - m in component INa (dimensionless): 0.003933
 - hf in component INa (dimensionless): 0.864900
 - hs in component INa (dimensionless): 0.864900
 - j in component INa (dimensionless): 0.864899
 - hsp in component INa (dimensionless): 0.698015
 - jp in component INa (dimensionless): 0.864899
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706813
 - hLp in component INaL (dimensionless): 0.512980
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999846
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999986
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003786
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002909
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997546
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:22:53 (128674): called boinc_finish(0)

</stderr_txt>
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