𝕏

Task 55562144

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_5000-conf_563_1
Workunit 26382093
Created 1 Jul 2024, 15:14:37 UTC
Sent 1 Jul 2024, 21:32:26 UTC
Report deadline 4 Jul 2024, 21:32:26 UTC
Received 3 Jul 2024, 15:54:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232340
Run time 2 hours 7 min 17 sec
CPU time 1 hours 51 min 15 sec
Validate state Valid
Credit 44.52
Device peak FLOPS 3.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 4.29 MB
Peak swap size 1.98 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_5000-conf_563.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_5000-conf_563_1_r88005960_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_5000-conf_563_1_r88005960_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.149476
     * GNaL_b in INaL: 0.005895
     * Gto_b in Ito: 0.082267
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032313
     * GKs_b in IKs: 0.001902
     * GK1_b in IK1: 0.164155
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.237876
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032102
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 4967581, states[0] = -94.398592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 12239945, states[0] = -94.320632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19396484, states[0] = -94.278114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26838155, states[0] = -94.252480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34164898, states[0] = -94.240218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40763112, states[0] = -94.260605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47660719, states[0] = -54.957968, states[40]= 0.000038
Saving checkpoint... 
Iteration: 55140140, states[0] = -31.589091, states[40]= 0.000349
Saving checkpoint... 
Iteration: 61952105, states[0] = -94.223275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68638689, states[0] = -94.243430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76252186, states[0] = -94.241110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83502442, states[0] = -94.252012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91220356, states[0] = -94.245420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98231964, states[0] = -94.265274, states[40]= 0.000000
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Iteration: 105681903, states[0] = -94.267083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112352267, states[0] = -94.228017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119657488, states[0] = -94.230917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126903181, states[0] = -94.235000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133955348, states[0] = -94.244433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140461497, states[0] = -94.239023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146951094, states[0] = -94.235770, states[40]= 0.000000
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Iteration: 154376832, states[0] = -94.237232, states[40]= 0.000000
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Iteration: 160799837, states[0] = -94.269306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167712226, states[0] = -93.614921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174705908, states[0] = -94.233609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181063664, states[0] = -94.259041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188790748, states[0] = -94.251128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194735567, states[0] = -94.233581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201103534, states[0] = -94.257697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207753474, states[0] = -93.866162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214741125, states[0] = -94.233609, states[40]= 0.000000
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Iteration: 220622637, states[0] = -94.271307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228442696, states[0] = -94.264274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236059714, states[0] = -94.259412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242728355, states[0] = -93.725741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249284008, states[0] = -94.239655, states[40]= 0.000000
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Iteration: 255929475, states[0] = -94.264711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263344783, states[0] = -94.268177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270621118, states[0] = -94.271002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277543417, states[0] = 26.188617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284762488, states[0] = -94.233050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292141025, states[0] = -94.234300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299401932, states[0] = -94.237394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306801254, states[0] = -94.238935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314038680, states[0] = -94.244054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321277416, states[0] = -94.251038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328694685, states[0] = -94.253704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336077162, states[0] = -94.257975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341302513, states[0] = -94.250080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348479752, states[0] = -94.261825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355443465, states[0] = -94.231025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362996962, states[0] = -94.252427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369992366, states[0] = -94.230241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377155759, states[0] = -94.233368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383891639, states[0] = -94.247105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390848077, states[0] = -94.266937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395960563, states[0] = -94.262190, states[40]= 0.000000
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Iteration: 403781490, states[0] = -94.250147, states[40]= 0.000000
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Iteration: 410445017, states[0] = -94.231334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417779074, states[0] = -93.971368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424828685, states[0] = -94.231133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430970354, states[0] = -94.261447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438162942, states[0] = -94.270661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445188243, states[0] = -92.434328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452412172, states[0] = -94.230122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459215745, states[0] = -94.239034, states[40]= 0.000000
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Iteration: 466377595, states[0] = -94.246713, states[40]= 0.000000
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Iteration: 473878772, states[0] = -94.246609, states[40]= 0.000000
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Iteration: 480328577, states[0] = -94.103710, states[40]= 0.000000
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Iteration: 487236193, states[0] = -94.231453, states[40]= 0.000000
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Iteration: 494391433, states[0] = -94.235738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501564839, states[0] = -94.241707, states[40]= 0.000000
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Iteration: 508562199, states[0] = -94.256942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515926846, states[0] = -94.262482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522981335, states[0] = -94.245946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529811772, states[0] = -94.230295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537210743, states[0] = -94.231246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543865272, states[0] = -94.246324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550414011, states[0] = -94.210462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557686360, states[0] = -91.624152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565021073, states[0] = 25.103158, states[40]= -0.000000
Saving checkpoint... 
Iteration: 572501798, states[0] = 29.629103, states[40]= 1.854455
Saving checkpoint... 
Iteration: 579562711, states[0] = -94.232559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586339155, states[0] = -94.246672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593898606, states[0] = -94.244925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601023041, states[0] = -94.257645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608317722, states[0] = -94.266052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615845154, states[0] = -94.264925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622831370, states[0] = -94.107772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630105658, states[0] = 0.420647, states[40]= 0.000157
Saving checkpoint... 
Iteration: 637475578, states[0] = -94.227838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645371989, states[0] = -94.169483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652733947, states[0] = -93.756539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659503184, states[0] = -94.232573, states[40]= 0.000000
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Iteration: 666917282, states[0] = -94.233713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673797398, states[0] = -94.247094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680801813, states[0] = -94.265944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688302536, states[0] = -94.265848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695204210, states[0] = -93.547720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702684370, states[0] = -90.205317, states[40]= 0.000000
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Iteration: 710318823, states[0] = -94.081114, states[40]= 0.000000
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Iteration: 717404577, states[0] = -94.227672, states[40]= 0.000000
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Iteration: 724646212, states[0] = -94.230181, states[40]= 0.000000
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Iteration: 731924762, states[0] = -94.232987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739082178, states[0] = -94.239073, states[40]= 0.000000
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Iteration: 746130598, states[0] = -94.252063, states[40]= 0.000000
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Iteration: 752190457, states[0] = -94.229425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759639083, states[0] = -94.229930, states[40]= 0.000000
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Iteration: 766241121, states[0] = -94.248005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772682791, states[0] = -88.557431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779518197, states[0] = -94.231234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786706061, states[0] = -94.236107, states[40]= 0.000000
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Iteration: 793912358, states[0] = -94.242657, states[40]= 0.000000
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Iteration: 801291032, states[0] = -94.246081, states[40]= 0.000000
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Iteration: 808229905, states[0] = -94.266785, states[40]= 0.000000
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Iteration: 815286551, states[0] = -93.993006, states[40]= 0.000000
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Iteration: 822903695, states[0] = -94.199712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830235030, states[0] = -93.761287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837364327, states[0] = -94.226886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844583425, states[0] = -94.229785, states[40]= 0.000000
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Iteration: 852296530, states[0] = -94.227380, states[40]= 0.000000
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Iteration: 859075929, states[0] = -94.238069, states[40]= 0.000000
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Iteration: 866642393, states[0] = -94.236593, states[40]= 0.000000
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Iteration: 873732242, states[0] = -94.247277, states[40]= 0.000000
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Iteration: 881214137, states[0] = -94.247813, states[40]= 0.000000
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Iteration: 888071008, states[0] = -94.261456, states[40]= 0.000000
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Iteration: 895433599, states[0] = -94.220314, states[40]= 0.000000
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Iteration: 902786839, states[0] = -93.993099, states[40]= 0.000000
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Iteration: 909692888, states[0] = -94.227901, states[40]= 0.000000
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Iteration: 916712098, states[0] = -94.234760, states[40]= 0.000000
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Iteration: 923601757, states[0] = -94.251468, states[40]= 0.000000
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Iteration: 930680920, states[0] = -94.266118, states[40]= 0.000000
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Iteration: 937292558, states[0] = -94.226613, states[40]= 0.000000
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Iteration: 944739560, states[0] = -94.227074, states[40]= 0.000000
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Iteration: 951480757, states[0] = -94.239408, states[40]= 0.000000
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Iteration: 958692719, states[0] = -94.247816, states[40]= 0.000000
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Iteration: 966209200, states[0] = -94.247178, states[40]= 0.000000
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Iteration: 973418572, states[0] = -94.258501, states[40]= 0.000000
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Iteration: 979930722, states[0] = -94.224955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986769220, states[0] = -94.233062, states[40]= 0.000000
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Iteration: 993746908, states[0] = -94.245659, states[40]= 0.000000
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Iteration: 1000620508, states[0] = -94.264149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008038876, states[0] = -94.255832, states[40]= 0.000000
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Iteration: 1014978580, states[0] = -94.224229, states[40]= 0.000000
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Iteration: 1021750868, states[0] = -94.233054, states[40]= 0.000000
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Iteration: 1029467258, states[0] = -94.229553, states[40]= 0.000000
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Iteration: 1036715494, states[0] = -94.233558, states[40]= 0.000000
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Iteration: 1043958653, states[0] = -94.239082, states[40]= 0.000000
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Iteration: 1051326542, states[0] = -94.242635, states[40]= 0.000000
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Iteration: 1058604153, states[0] = -94.250097, states[40]= 0.000000
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Iteration: 1066053067, states[0] = -94.252025, states[40]= 0.000000
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Iteration: 1073139467, states[0] = -94.264177, states[40]= 0.000000
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Iteration: 1080338751, states[0] = -94.116917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087558614, states[0] = 23.014770, states[40]= 0.000000
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Iteration: 1094743992, states[0] = -94.225604, states[40]= 0.000000
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Iteration: 1102154387, states[0] = -94.226502, states[40]= 0.000000
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Iteration: 1109409965, states[0] = -94.229621, states[40]= 0.000000
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Iteration: 1116768970, states[0] = -94.231832, states[40]= 0.000000
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Iteration: 1123634323, states[0] = -94.248347, states[40]= 0.000000
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Iteration: 1131239261, states[0] = -94.244606, states[40]= 0.000000
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Iteration: 1138289154, states[0] = -94.262049, states[40]= 0.000000
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Iteration: 1145298224, states[0] = -94.025282, states[40]= 0.000000
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Iteration: 1152283629, states[0] = -94.224659, states[40]= 0.000000
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Iteration: 1159551040, states[0] = -94.227202, states[40]= 0.000000
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Iteration: 1167138072, states[0] = -94.226074, states[40]= 0.000000
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Iteration: 1174248721, states[0] = -94.231648, states[40]= 0.000000
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Iteration: 1181575746, states[0] = -94.235017, states[40]= 0.000000
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Iteration: 1188201150, states[0] = -94.263606, states[40]= 0.000000
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Iteration: 1195660903, states[0] = -94.263471, states[40]= 0.000000
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Iteration: 1202526093, states[0] = 26.046060, states[40]= 0.000000
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Iteration: 1209173681, states[0] = -94.232723, states[40]= 0.000000
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Iteration: 1216029713, states[0] = -94.251549, states[40]= 0.000000
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Iteration: 1222333524, states[0] = -94.223516, states[40]= 0.000000
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Iteration: 1229343841, states[0] = -94.229509, states[40]= 0.000000
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Iteration: 1234964248, states[0] = -94.222257, states[40]= 0.000000
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Iteration: 1241830643, states[0] = -94.229604, states[40]= 0.000000
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Iteration: 1249231380, states[0] = -94.231250, states[40]= 0.000000
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Iteration: 1256338845, states[0] = -94.240330, states[40]= 0.000000
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Iteration: 1263851725, states[0] = -94.239886, states[40]= 0.000000
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Iteration: 1270573171, states[0] = -94.258075, states[40]= 0.000000
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Iteration: 1277796697, states[0] = -94.019651, states[40]= 0.000000
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Iteration: 1285789438, states[0] = -94.260645, states[40]= 0.000000
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Iteration: 1292654116, states[0] = -49.793860, states[40]= 0.000091
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Iteration: 1299947005, states[0] = -94.221781, states[40]= 0.000000
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Iteration: 1306270060, states[0] = -94.241952, states[40]= 0.000000
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Iteration: 1313776664, states[0] = -94.241671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320946462, states[0] = -94.254027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327937454, states[0] = -94.218475, states[40]= 0.000000
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Iteration: 1334675236, states[0] = -94.224061, states[40]= 0.000000
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Iteration: 1340673032, states[0] = -94.262211, states[40]= 0.000000
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Iteration: 1347398141, states[0] = -94.221744, states[40]= 0.000000
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Iteration: 1354789715, states[0] = -94.222676, states[40]= 0.000000
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Iteration: 1362312155, states[0] = -94.222387, states[40]= 0.000000
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Iteration: 1369679936, states[0] = -94.223676, states[40]= 0.000000
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Iteration: 1376812497, states[0] = -94.228620, states[40]= 0.000000
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Iteration: 1384255954, states[0] = -94.229523, states[40]= 0.000000
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Iteration: 1391215615, states[0] = -94.242930, states[40]= 0.000000
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Iteration: 1398180849, states[0] = -94.261694, states[40]= 0.000000
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Iteration: 1404813649, states[0] = -94.221969, states[40]= 0.000000
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Iteration: 1411863062, states[0] = -94.227468, states[40]= 0.000000
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Iteration: 1418363096, states[0] = -94.256605, states[40]= 0.000000
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Iteration: 1425358976, states[0] = -94.145258, states[40]= 0.000000
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Iteration: 1432717140, states[0] = -93.639167, states[40]= 0.000000
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Iteration: 1440084764, states[0] = 12.564802, states[40]= 0.000018
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Iteration: 1447235557, states[0] = -94.222344, states[40]= 0.000000
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Iteration: 1453199542, states[0] = -94.261109, states[40]= 0.000000
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Iteration: 1460246726, states[0] = -93.820517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467415851, states[0] = -94.220451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475045093, states[0] = 25.976083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482371973, states[0] = -94.220693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489791363, states[0] = -94.221377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497051169, states[0] = -94.223995, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.095429
 - CaMKt in component CaMK (millimolar): 0.001699
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.094185
 - nass in component intracellular_ions (millimolar): 7.094321
 - ki in component intracellular_ions (millimolar): 144.605214
 - kss in component intracellular_ions (millimolar): 144.605200
 - cansr in component intracellular_ions (millimolar): 2.394732
 - cajsr in component intracellular_ions (millimolar): 2.395054
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003925
 - hf in component INa (dimensionless): 0.865287
 - hs in component INa (dimensionless): 0.865288
 - j in component INa (dimensionless): 0.865289
 - hsp in component INa (dimensionless): 0.698717
 - jp in component INa (dimensionless): 0.865291
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707400
 - hLp in component INaL (dimensionless): 0.513674
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998810
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005312
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001771
 - xs1 in component IKs (dimensionless): 0.023325
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997541
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:32:32 (19200): called boinc_finish(0)

</stderr_txt>
]]>


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