𝕏

Task 55559895

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_361_0
Workunit 26380971
Created 1 Jul 2024, 15:13:34 UTC
Sent 1 Jul 2024, 21:19:38 UTC
Report deadline 4 Jul 2024, 21:19:38 UTC
Received 2 Jul 2024, 9:56:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233458
Run time 1 hours 53 min 48 sec
CPU time 1 hours 53 min 21 sec
Validate state Valid
Credit 50.12
Device peak FLOPS 3.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.20 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_361.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_361_0_r1734025587_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_361_0_r1734025587_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.876276
     * GNaL_b in INaL: 0.005441
     * Gto_b in Ito: 0.085022
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032177
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.167298
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 69.607716
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030418
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5847318, states[0] = -94.162349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14323935, states[0] = -94.068806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22874208, states[0] = -94.019361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31439057, states[0] = -93.999243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40040480, states[0] = -93.997167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48801214, states[0] = -93.996337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57435264, states[0] = -93.911689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65932921, states[0] = -93.951667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74372725, states[0] = -93.954567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83056497, states[0] = -93.957417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90273338, states[0] = -93.575990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98709805, states[0] = -93.950477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107173124, states[0] = -93.955136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115662252, states[0] = -93.962998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124218386, states[0] = -93.974815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132689997, states[0] = -93.985829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141219319, states[0] = -92.343528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149847888, states[0] = -93.948962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158491411, states[0] = -93.951484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167078733, states[0] = -93.955788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175687737, states[0] = -93.962076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184386196, states[0] = -93.969273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193040711, states[0] = -93.980782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201320074, states[0] = -93.728104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207031938, states[0] = 29.897384, states[40]= 0.000139
Saving checkpoint... 
Iteration: 215497888, states[0] = -93.951250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224062293, states[0] = -93.955841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232637878, states[0] = -93.962955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241364662, states[0] = -93.969755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249881660, states[0] = -93.985940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258414908, states[0] = -93.887080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266952310, states[0] = -93.948030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275575821, states[0] = -93.950499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284230366, states[0] = -93.953701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293020957, states[0] = -93.956268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301775046, states[0] = -93.960141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310453889, states[0] = -93.967165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319373181, states[0] = -93.969370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327134852, states[0] = -20.034125, states[40]= 0.001806
Saving checkpoint... 
Iteration: 335727333, states[0] = -93.949291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344243670, states[0] = -93.953453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352792952, states[0] = -93.959734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361424283, states[0] = -93.967870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370115114, states[0] = -93.977738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378764369, states[0] = -93.987239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384655903, states[0] = -93.982827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393075763, states[0] = 15.311071, states[40]= 0.001294
Saving checkpoint... 
Iteration: 401485280, states[0] = -93.951026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410057145, states[0] = -93.955584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418552738, states[0] = -93.964531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427145048, states[0] = -93.976572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435777610, states[0] = -93.987189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444428461, states[0] = -93.899771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453046464, states[0] = 25.895868, states[40]= 0.000258
Saving checkpoint... 
Iteration: 461743645, states[0] = -93.948972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470418670, states[0] = -93.951500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478892492, states[0] = -93.957856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487588538, states[0] = -93.963596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496257234, states[0] = -93.972631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505154468, states[0] = -93.976109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514034800, states[0] = -93.980426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522811319, states[0] = -93.986859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531312987, states[0] = -93.708528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539845007, states[0] = -93.948197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548572532, states[0] = -93.950069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555330647, states[0] = -93.753413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563885734, states[0] = -93.947913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572397940, states[0] = -93.951522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580919865, states[0] = -93.957260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589471928, states[0] = -93.966233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598046501, states[0] = -93.979861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606600602, states[0] = -93.975598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615131047, states[0] = -17.001186, states[40]= 0.001691
Saving checkpoint... 
Iteration: 623661083, states[0] = -93.949278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632207567, states[0] = -93.953376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640732581, states[0] = -93.960366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649278533, states[0] = -93.971693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657948765, states[0] = -93.983225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667434109, states[0] = -93.967099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675779025, states[0] = -93.986794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684580149, states[0] = -93.971647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693250174, states[0] = -93.470686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701794997, states[0] = -93.948241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710424282, states[0] = -93.951052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719181030, states[0] = -93.953537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728011477, states[0] = -93.955678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736702959, states[0] = -93.960780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745712539, states[0] = -93.960578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754206926, states[0] = -93.973878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762839989, states[0] = -93.986033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771370465, states[0] = -93.829545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779891926, states[0] = -93.947520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788533742, states[0] = -93.949982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793655035, states[0] = -93.961654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802330689, states[0] = -93.969824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810965351, states[0] = -93.982411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819465957, states[0] = -93.927547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827937569, states[0] = -93.947179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836498808, states[0] = -93.950192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845152062, states[0] = -93.953670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853643492, states[0] = -93.961797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862269690, states[0] = -93.971625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870875955, states[0] = -93.985056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879620354, states[0] = -93.978117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888265569, states[0] = -93.540852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896968893, states[0] = -93.946892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905676685, states[0] = -93.948700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914455757, states[0] = -93.950434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923277945, states[0] = -93.952129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932101087, states[0] = -93.954153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940642880, states[0] = -93.961666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949300659, states[0] = -93.970502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957920176, states[0] = -93.983654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966213445, states[0] = -89.221579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974721653, states[0] = -93.948273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983252701, states[0] = -93.952299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991851232, states[0] = -93.957678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000413086, states[0] = -93.967122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009013031, states[0] = -93.980400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017526509, states[0] = -93.956314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025238794, states[0] = -93.952380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033773194, states[0] = -93.958963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042432964, states[0] = -93.966511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050987386, states[0] = -93.981248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059547654, states[0] = -93.963026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068273885, states[0] = -93.575369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077098807, states[0] = 5.145680, states[40]= 0.003111
Saving checkpoint... 
Iteration: 1085595307, states[0] = -93.949004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093554251, states[0] = -93.963382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093730777, states[0] = -93.959652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096581096, states[0] = -93.962759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105267946, states[0] = -93.971280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113848133, states[0] = -93.985296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122455746, states[0] = -93.920280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131018299, states[0] = 31.673122, states[40]= 0.003376
Saving checkpoint... 
Iteration: 1139661675, states[0] = -93.948421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148166209, states[0] = -93.953001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156703788, states[0] = -93.960070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165345425, states[0] = -93.968784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173963068, states[0] = -93.981892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182481524, states[0] = -93.936088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190989366, states[0] = -93.946295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199721015, states[0] = -93.947905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206382284, states[0] = -93.846340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215045755, states[0] = 26.119824, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1223698333, states[0] = -93.948022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232327054, states[0] = -93.951115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240889827, states[0] = -93.956640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249567545, states[0] = -93.962816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258249103, states[0] = -93.971639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266947359, states[0] = -93.982269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275544016, states[0] = -93.961601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284295548, states[0] = -93.654407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293085365, states[0] = 11.343389, states[40]= 0.001985
Saving checkpoint... 
Iteration: 1301736379, states[0] = -93.947633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310478933, states[0] = -93.949578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319241790, states[0] = -93.951862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327994713, states[0] = -93.954922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336779356, states[0] = -93.958351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345544373, states[0] = -93.963198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354448126, states[0] = -93.965592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363100612, states[0] = -93.976626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371611773, states[0] = -93.976097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380156006, states[0] = -35.897417, states[40]= 0.001424
Saving checkpoint... 
Iteration: 1388807760, states[0] = -93.947024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397499341, states[0] = -93.949261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405947926, states[0] = -93.955473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414515015, states[0] = -93.963790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422970343, states[0] = -93.981231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431552388, states[0] = -93.963747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440244086, states[0] = -93.439169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445575573, states[0] = -93.948562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454008388, states[0] = -93.954522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462832636, states[0] = -93.957212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471532881, states[0] = -93.963263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480249833, states[0] = -93.971249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488866043, states[0] = -93.984282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497384251, states[0] = -93.848582, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.821707
 - CaMKt in component CaMK (millimolar): 0.001330
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.711735
 - nass in component intracellular_ions (millimolar): 6.711862
 - ki in component intracellular_ions (millimolar): 145.150280
 - kss in component intracellular_ions (millimolar): 145.150270
 - cansr in component intracellular_ions (millimolar): 1.842656
 - cajsr in component intracellular_ions (millimolar): 1.842525
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004035
 - hf in component INa (dimensionless): 0.859958
 - hs in component INa (dimensionless): 0.859958
 - j in component INa (dimensionless): 0.859959
 - hsp in component INa (dimensionless): 0.689164
 - jp in component INa (dimensionless): 0.859960
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699768
 - hLp in component INaL (dimensionless): 0.504581
 - a in component Ito (dimensionless): 0.000671
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.999232
 - ap in component Ito (dimensionless): 0.000342
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.999702
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999526
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005587
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000577
 - xs1 in component IKs (dimensionless): 0.014627
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997607
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:55:01 (4708): called boinc_finish(0)

</stderr_txt>
]]>


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