𝕏

Task 55559673

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_261_0
Workunit 26380860
Created 1 Jul 2024, 15:13:29 UTC
Sent 1 Jul 2024, 21:17:30 UTC
Report deadline 5 Jul 2024, 0:10:18 UTC
Received 2 Jul 2024, 2:36:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 2 hours 10 min 33 sec
CPU time 2 hours 4 min 10 sec
Validate state Valid
Credit 48.85
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.73 MB
Peak swap size 32.57 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_261.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_261_0_r1594177818_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_261_0_r1594177818_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.033446
     * GNaL_b in INaL: 0.006052
     * Gto_b in Ito: 0.083583
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009437
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.160128
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.362921
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030693
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13491688, states[0] = -94.882238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27058074, states[0] = 20.162378, states[40]= 0.003940
Saving checkpoint... 
Iteration: 40296490, states[0] = -90.630398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53801694, states[0] = -91.456713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67334423, states[0] = -94.634080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80842258, states[0] = -94.639434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94369388, states[0] = -94.672682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107864529, states[0] = -94.662246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121352675, states[0] = -94.642575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134876390, states[0] = -94.671861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148103519, states[0] = 6.308078, states[40]= 0.005177
Saving checkpoint... 
Iteration: 161621236, states[0] = -0.195644, states[40]= 0.004700
Saving checkpoint... 
Iteration: 174916354, states[0] = -94.706930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188429024, states[0] = -94.715606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201787695, states[0] = -64.379567, states[40]= 0.000019
Saving checkpoint... 
Iteration: 215067969, states[0] = 18.264219, states[40]= 0.004649
Saving checkpoint... 
Iteration: 228566004, states[0] = 18.872582, states[40]= 0.004569
Saving checkpoint... 
Iteration: 241972092, states[0] = -94.738364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255221151, states[0] = -34.648303, states[40]= 0.002081
Saving checkpoint... 
Iteration: 268113459, states[0] = 2.809230, states[40]= 0.005002
Saving checkpoint... 
Iteration: 281354571, states[0] = -94.637342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294300926, states[0] = -76.973583, states[40]= 0.000002
Saving checkpoint... 
Iteration: 307624782, states[0] = -1.488624, states[40]= 0.004502
Saving checkpoint... 
Iteration: 320968968, states[0] = -94.736422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334132426, states[0] = -4.581160, states[40]= 0.003925
Saving checkpoint... 
Iteration: 347480042, states[0] = -94.741137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360521567, states[0] = 30.798544, states[40]= 0.003714
Saving checkpoint... 
Iteration: 373864324, states[0] = -94.650613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387113082, states[0] = 2.953874, states[40]= 0.005012
Saving checkpoint... 
Iteration: 400451444, states[0] = -94.727396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414419641, states[0] = -94.706825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427645995, states[0] = -10.393634, states[40]= 0.002809
Saving checkpoint... 
Iteration: 441168833, states[0] = -19.152152, states[40]= 0.004551
Saving checkpoint... 
Iteration: 454672871, states[0] = -20.392808, states[40]= 0.004981
Saving checkpoint... 
Iteration: 468152391, states[0] = -13.116305, states[40]= 0.002662
Saving checkpoint... 
Iteration: 481641717, states[0] = -8.539042, states[40]= 0.003105
Saving checkpoint... 
Iteration: 495126196, states[0] = -2.045023, states[40]= 0.004410
Saving checkpoint... 
Iteration: 508803878, states[0] = -81.046798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522322140, states[0] = -94.382490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535859008, states[0] = -94.642946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549117342, states[0] = 1.372637, states[40]= 0.004875
Saving checkpoint... 
Iteration: 562672172, states[0] = -20.182336, states[40]= 0.004923
Saving checkpoint... 
Iteration: 575957543, states[0] = -94.730217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589527147, states[0] = 29.812606, states[40]= 0.003002
Saving checkpoint... 
Iteration: 603065190, states[0] = 19.130528, states[40]= 0.004535
Saving checkpoint... 
Iteration: 616588757, states[0] = 11.519676, states[40]= 0.005149
Saving checkpoint... 
Iteration: 629824406, states[0] = -94.482929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643343099, states[0] = -94.618218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656780316, states[0] = -59.472185, states[40]= 0.000045
Saving checkpoint... 
Iteration: 670312976, states[0] = -92.010310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683549046, states[0] = 23.909176, states[40]= 0.003697
Saving checkpoint... 
Iteration: 696995095, states[0] = -94.746026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710515878, states[0] = 31.216168, states[40]= 0.008929
Saving checkpoint... 
Iteration: 724027320, states[0] = 29.775724, states[40]= 0.002997
Saving checkpoint... 
Iteration: 737491703, states[0] = -94.744716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750709952, states[0] = -31.045037, states[40]= 0.003132
Saving checkpoint... 
Iteration: 764214885, states[0] = -32.588280, states[40]= 0.002649
Saving checkpoint... 
Iteration: 777736655, states[0] = -40.073324, states[40]= 0.001028
Saving checkpoint... 
Iteration: 791253794, states[0] = -46.837296, states[40]= 0.000381
Saving checkpoint... 
Iteration: 804416989, states[0] = -94.703882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817502840, states[0] = 41.252037, states[40]= 0.340175
Saving checkpoint... 
Iteration: 831046436, states[0] = 24.665012, states[40]= 0.003557
Saving checkpoint... 
Iteration: 844576595, states[0] = 15.549849, states[40]= 0.004932
Saving checkpoint... 
Iteration: 858072837, states[0] = 16.752613, states[40]= 0.004823
Saving checkpoint... 
Iteration: 871528661, states[0] = 29.478955, states[40]= 0.002973
Saving checkpoint... 
Iteration: 884986942, states[0] = -94.742595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898555996, states[0] = 21.880554, states[40]= 0.004080
Saving checkpoint... 
Iteration: 912039288, states[0] = 26.708923, states[40]= 0.003219
Saving checkpoint... 
Iteration: 925571158, states[0] = 17.282764, states[40]= 0.004767
Saving checkpoint... 
Iteration: 938900902, states[0] = -94.689979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952373131, states[0] = -94.660478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965798591, states[0] = -74.023050, states[40]= 0.000004
Saving checkpoint... 
Iteration: 979088655, states[0] = 11.554515, states[40]= 0.005148
Saving checkpoint... 
Iteration: 992529481, states[0] = 29.289306, states[40]= 0.002969
Saving checkpoint... 
Iteration: 1006016437, states[0] = 31.209334, states[40]= 0.007882
Saving checkpoint... 
Iteration: 1019355834, states[0] = -94.637294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032519116, states[0] = 31.068263, states[40]= 0.004869
Saving checkpoint... 
Iteration: 1045332098, states[0] = -94.588251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058601007, states[0] = 7.289407, states[40]= 0.005186
Saving checkpoint... 
Iteration: 1071682313, states[0] = -23.114795, states[40]= 0.005200
Saving checkpoint... 
Iteration: 1084903398, states[0] = -94.691899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098246231, states[0] = -43.750951, states[40]= 0.000609
Saving checkpoint... 
Iteration: 1111584621, states[0] = 12.911527, states[40]= 0.005096
Saving checkpoint... 
Iteration: 1125074188, states[0] = 16.322980, states[40]= 0.004864
Saving checkpoint... 
Iteration: 1138131831, states[0] = -4.331483, states[40]= 0.003976
Saving checkpoint... 
Iteration: 1151780236, states[0] = -59.424233, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1165598067, states[0] = 8.319089, states[40]= 0.005194
Saving checkpoint... 
Iteration: 1179250780, states[0] = -45.587241, states[40]= 0.000462
Saving checkpoint... 
Iteration: 1192648136, states[0] = -11.314817, states[40]= 0.002710
Saving checkpoint... 
Iteration: 1205428597, states[0] = -94.711456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218151861, states[0] = -12.894254, states[40]= 0.002655
Saving checkpoint... 
Iteration: 1231111109, states[0] = 3.676874, states[40]= 0.005059
Saving checkpoint... 
Iteration: 1244879926, states[0] = -94.667804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258613106, states[0] = 2.946295, states[40]= 0.005011
Saving checkpoint... 
Iteration: 1272360214, states[0] = -94.642918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286033419, states[0] = 28.309002, states[40]= 0.003023
Saving checkpoint... 
Iteration: 1299738553, states[0] = -40.781592, states[40]= 0.000932
Saving checkpoint... 
Iteration: 1313493433, states[0] = -94.744010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327024823, states[0] = 30.276664, states[40]= 0.003135
Saving checkpoint... 
Iteration: 1340758505, states[0] = -48.842807, states[40]= 0.000277
Saving checkpoint... 
Iteration: 1354333051, states[0] = -94.591843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368061543, states[0] = 20.234124, states[40]= 0.004367
Saving checkpoint... 
Iteration: 1381816562, states[0] = -93.585045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395553613, states[0] = 22.579715, states[40]= 0.003950
Saving checkpoint... 
Iteration: 1409321813, states[0] = -94.359290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422800361, states[0] = -76.182824, states[40]= 0.000003


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_261.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_261_0_r1594177818_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_261_0_r1594177818_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.033446
     * GNaL_b in INaL: 0.006052
     * Gto_b in Ito: 0.083583
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009437
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.160128
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.362921
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030693
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1422800361
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -76.182824 (After loading)
 - states[40]: 0.000003 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1436586800, states[0] = 12.181194, states[40]= 0.005127
Saving checkpoint... 
Iteration: 1450321514, states[0] = -94.338659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464123810, states[0] = -1.102956, states[40]= 0.004562
Saving checkpoint... 
Iteration: 1477920999, states[0] = -94.705374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491907927, states[0] = -94.694910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505780926, states[0] = 26.175444, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1519487598, states[0] = -94.556007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533181185, states[0] = -94.705191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546861045, states[0] = 6.837970, states[40]= 0.004885
Saving checkpoint... 
Iteration: 1560509951, states[0] = -94.488593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574128513, states[0] = 3.141430, states[40]= 0.004557
Saving checkpoint... 
Iteration: 1587624089, states[0] = 6.032890, states[40]= 0.004577
Saving checkpoint... 
Iteration: 1601123962, states[0] = 6.224965, states[40]= 0.004558
Saving checkpoint... 
Iteration: 1614707668, states[0] = -18.411769, states[40]= 0.006033
Saving checkpoint... 
Iteration: 1628245542, states[0] = -94.381836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641765066, states[0] = -94.383731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655316226, states[0] = -27.163942, states[40]= 0.005301
Saving checkpoint... 
Iteration: 1668808511, states[0] = -94.389226, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.249256
 - CaMKt in component CaMK (millimolar): 0.001285
 - cass in component intracellular_ions (millimolar): 0.000082
 - nai in component intracellular_ions (millimolar): 6.144938
 - nass in component intracellular_ions (millimolar): 6.145011
 - ki in component intracellular_ions (millimolar): 145.784139
 - kss in component intracellular_ions (millimolar): 145.784132
 - cansr in component intracellular_ions (millimolar): 1.474505
 - cajsr in component intracellular_ions (millimolar): 1.473906
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.003865
 - hf in component INa (dimensionless): 0.868206
 - hs in component INa (dimensionless): 0.868207
 - j in component INa (dimensionless): 0.868208
 - hsp in component INa (dimensionless): 0.704010
 - jp in component INa (dimensionless): 0.868209
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.711632
 - hLp in component INaL (dimensionless): 0.518387
 - a in component Ito (dimensionless): 0.000652
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.995636
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.998404
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997395
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002419
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.003800
 - xs1 in component IKs (dimensionless): 0.037400
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997503
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:39:42 (85193): called boinc_finish(0)

</stderr_txt>
]]>


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