𝕏

Task 55558989

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_6000-conf_960_0
Workunit 26380518
Created 1 Jul 2024, 15:13:13 UTC
Sent 1 Jul 2024, 21:17:25 UTC
Report deadline 4 Jul 2024, 21:17:25 UTC
Received 2 Jul 2024, 2:45:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241398
Run time 2 hours 54 min 54 sec
CPU time 2 hours 54 min 54 sec
Validate state Valid
Credit 42.27
Device peak FLOPS 1.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.68 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_6000-conf_960.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_6000-conf_960_0_r826096925_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_6000-conf_960_0_r826096925_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.987527
     * GNaL_b in INaL: 0.006087
     * Gto_b in Ito: 0.087404
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031527
     * GKs_b in IKs: 0.001917
     * GK1_b in IK1: 0.164488
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.441335
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034892
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9489537, states[0] = -94.348107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19099830, states[0] = -94.296669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28599357, states[0] = -94.252422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38081182, states[0] = -94.228638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47704506, states[0] = -94.216159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57197089, states[0] = -93.130070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66571531, states[0] = -94.248818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76208043, states[0] = -94.238442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85860302, states[0] = -94.225716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95346333, states[0] = -94.222009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104901045, states[0] = -94.220072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114479268, states[0] = -94.237194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124032915, states[0] = -94.252606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133624434, states[0] = -94.236532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143096900, states[0] = -94.230089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152707311, states[0] = -94.225599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162230290, states[0] = -93.727717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171681398, states[0] = -94.266540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181253521, states[0] = -94.247820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190822354, states[0] = -94.235289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200445296, states[0] = -94.228468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209962883, states[0] = -94.225491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219331808, states[0] = -94.104405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228821827, states[0] = -94.264156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238201681, states[0] = -94.249777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247790453, states[0] = -94.235929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257247322, states[0] = -94.230166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266755989, states[0] = -94.226400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276229629, states[0] = -93.724364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285688581, states[0] = -94.266826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295263894, states[0] = -94.247513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304844344, states[0] = -94.234754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314493962, states[0] = -94.227741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324267156, states[0] = -93.917653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333909140, states[0] = -94.260209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343412836, states[0] = -94.243002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352930830, states[0] = -94.233145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362382165, states[0] = -94.228238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371887649, states[0] = -94.224970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381445953, states[0] = -94.225847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390916929, states[0] = -94.259447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400329042, states[0] = -94.244794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409861316, states[0] = -94.233681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419297982, states[0] = -94.228507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428967924, states[0] = -94.224147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438494173, states[0] = -94.245018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447921811, states[0] = -94.258791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457290164, states[0] = -94.245456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466811327, states[0] = -94.233984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476427898, states[0] = -94.226952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485991147, states[0] = -94.223585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495535670, states[0] = -94.254525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505231257, states[0] = -94.246871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514823508, states[0] = -94.233404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524460462, states[0] = -94.226311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534108281, states[0] = 0.228143, states[40]= 0.000192
Saving checkpoint... 
Iteration: 543612576, states[0] = -94.262851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553258901, states[0] = -94.245621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562934305, states[0] = -94.231403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572402996, states[0] = -94.226371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581856763, states[0] = -94.223420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591418945, states[0] = -94.207493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601172283, states[0] = -94.248031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610911201, states[0] = -94.231334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620427029, states[0] = -94.225792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629989994, states[0] = -94.222423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639585999, states[0] = -94.260105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649262753, states[0] = -94.244727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658900727, states[0] = -94.231094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668608479, states[0] = -94.224113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678330803, states[0] = -94.099078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687882974, states[0] = -94.258405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697612963, states[0] = -94.235631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707209007, states[0] = -94.227018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716761716, states[0] = -94.222815, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_6000-conf_960.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_6000-conf_960_0_r826096925_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_EPI_6000-conf_960_0_r826096925_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.987527
     * GNaL_b in INaL: 0.006087
     * Gto_b in Ito: 0.087404
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031527
     * GKs_b in IKs: 0.001917
     * GK1_b in IK1: 0.164488
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.441335
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034892
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 716761716
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.222815 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 726367114, states[0] = -94.156218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735978257, states[0] = -94.254184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745566375, states[0] = -94.236194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754931133, states[0] = -94.229888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764208076, states[0] = -94.226563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773674725, states[0] = -94.222847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782936367, states[0] = -94.221412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792422110, states[0] = -94.208083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801815329, states[0] = -94.260017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811309946, states[0] = -94.242009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820602927, states[0] = -94.234832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829997584, states[0] = -94.228403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839489096, states[0] = -94.223541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849024795, states[0] = 25.508637, states[40]= -0.000000
Saving checkpoint... 
Iteration: 858518662, states[0] = -94.248097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868143238, states[0] = -94.246868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877695879, states[0] = -94.232596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887126235, states[0] = -94.226422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896756502, states[0] = -94.221381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906287903, states[0] = -93.988861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915782553, states[0] = -94.260157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925298474, states[0] = -94.241419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934696137, states[0] = -94.232130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944386835, states[0] = -94.223482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953829470, states[0] = -94.220535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963468034, states[0] = -94.231465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973097109, states[0] = -94.247676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982623687, states[0] = -94.233107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992071851, states[0] = -94.226186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001535731, states[0] = -94.221895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011095116, states[0] = 8.166106, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1020712348, states[0] = -94.260811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030292542, states[0] = -94.240743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039870271, states[0] = -94.228439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049365843, states[0] = -94.222803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058850245, states[0] = -94.219578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068340357, states[0] = -94.113435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078005593, states[0] = -94.250325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087544271, states[0] = -94.233893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096978773, states[0] = -94.226477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106366315, states[0] = -94.222336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115863329, states[0] = -94.219050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125348372, states[0] = -94.126264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134948361, states[0] = -94.252156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144572813, states[0] = -94.232823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154009659, states[0] = -94.225620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163394449, states[0] = -94.221640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173042366, states[0] = 26.307465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182582486, states[0] = -94.255378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192226069, states[0] = -94.241468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201704704, states[0] = -94.229809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211232803, states[0] = -94.222691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220772479, states[0] = -94.218664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230354009, states[0] = -94.134051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239875395, states[0] = -94.254233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249307149, states[0] = -94.238540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258815996, states[0] = -94.227485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268351020, states[0] = -94.221151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277903763, states[0] = -94.217543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287512879, states[0] = -94.243262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297049828, states[0] = -94.246827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306582419, states[0] = -94.231310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316099008, states[0] = -94.223244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325289796, states[0] = -94.221229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334652382, states[0] = -94.218428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344137939, states[0] = -27.661075, states[40]= 0.000495
Saving checkpoint... 
Iteration: 1353744547, states[0] = -94.257596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363308267, states[0] = -94.237584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372742909, states[0] = -94.227757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382347630, states[0] = -94.220256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391826994, states[0] = -94.216992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401443650, states[0] = -94.216352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411021486, states[0] = -94.247004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420400313, states[0] = -94.234605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430079417, states[0] = -94.222544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439666720, states[0] = -94.217490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449226001, states[0] = -93.691596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458753446, states[0] = -94.256548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468169685, states[0] = -94.241095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477694025, states[0] = -94.227765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487171288, states[0] = -94.221073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496529563, states[0] = -94.217920, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.091295
 - CaMKt in component CaMK (millimolar): 0.001368
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.074506
 - nass in component intracellular_ions (millimolar): 7.074641
 - ki in component intracellular_ions (millimolar): 144.638286
 - kss in component intracellular_ions (millimolar): 144.638273
 - cansr in component intracellular_ions (millimolar): 2.380505
 - cajsr in component intracellular_ions (millimolar): 2.380819
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003927
 - hf in component INa (dimensionless): 0.865208
 - hs in component INa (dimensionless): 0.865208
 - j in component INa (dimensionless): 0.865209
 - hsp in component INa (dimensionless): 0.698573
 - jp in component INa (dimensionless): 0.865210
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707274
 - hLp in component INaL (dimensionless): 0.513570
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999555
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005284
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000471
 - xs1 in component IKs (dimensionless): 0.014282
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997542
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:24:38 (25916): called boinc_finish(0)

</stderr_txt>
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