𝕏

Task 55558777

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_460_0
Workunit 26380412
Created 1 Jul 2024, 15:13:08 UTC
Sent 1 Jul 2024, 21:12:10 UTC
Report deadline 4 Jul 2024, 21:12:10 UTC
Received 4 Jul 2024, 1:30:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 242119
Run time 1 hours 45 min 48 sec
CPU time 1 hours 41 min 9 sec
Validate state Valid
Credit 42.71
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_460.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_460_0_r671134009_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_460_0_r671134009_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.624315
     * GNaL_b in INaL: 0.005963
     * Gto_b in Ito: 0.084853
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032343
     * GKs_b in IKs: 0.001904
     * GK1_b in IK1: 0.160451
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.742839
     * GKb_b in IKb: 0.003819
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031288
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8981152, states[0] = -94.139062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17567196, states[0] = -94.076259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26001142, states[0] = -94.016367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35061526, states[0] = -94.017702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43793479, states[0] = -93.707081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52785766, states[0] = -93.675259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61389582, states[0] = -93.997690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70085693, states[0] = -94.008778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78661504, states[0] = -94.017120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87406884, states[0] = -93.918440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96116334, states[0] = -6.938100, states[40]= 0.003010
Saving checkpoint... 
Iteration: 104879331, states[0] = -93.995914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113757881, states[0] = -94.000279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122558136, states[0] = -94.008632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130859883, states[0] = -93.854647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139875266, states[0] = -93.878538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148787530, states[0] = -93.675566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157271895, states[0] = -93.999402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166224683, states[0] = -94.001221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174759122, states[0] = -94.018546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183341169, states[0] = -93.819786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192134141, states[0] = -21.669792, states[40]= 0.001826
Saving checkpoint... 
Iteration: 200984150, states[0] = -93.991840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209965138, states[0] = -93.992401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218796302, states[0] = -93.998211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227703308, states[0] = -94.001845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236709174, states[0] = -94.001574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245550393, states[0] = -94.008383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254508707, states[0] = -94.010207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263398827, states[0] = -94.014801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271989720, states[0] = -93.977537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281054851, states[0] = -94.000317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289657783, states[0] = -40.141331, states[40]= 0.000808
Saving checkpoint... 
Iteration: 298399096, states[0] = -93.994264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307345164, states[0] = -93.996118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316245916, states[0] = -93.999835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324793104, states[0] = -94.017681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333745311, states[0] = -94.017993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342405229, states[0] = -93.915196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351054060, states[0] = 22.940191, states[40]= 0.000451
Saving checkpoint... 
Iteration: 359849214, states[0] = -93.995804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368679332, states[0] = -94.002380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377651514, states[0] = -94.003527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386493350, states[0] = -94.010460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395512292, states[0] = -94.009594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404360506, states[0] = -94.015713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413235560, states[0] = -94.017681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422176034, states[0] = -94.015965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430570464, states[0] = 16.841117, states[40]= 0.001097
Saving checkpoint... 
Iteration: 439434433, states[0] = -93.992637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448008626, states[0] = -94.009590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456561504, states[0] = -94.001343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465017977, states[0] = 31.627227, states[40]= 0.003742
Saving checkpoint... 
Iteration: 473649253, states[0] = -94.003318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482615378, states[0] = -94.004752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491072664, states[0] = -94.003656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499778312, states[0] = -93.640700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508839292, states[0] = -93.814861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517712660, states[0] = -91.648464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526676733, states[0] = -55.695294, states[40]= 0.000091
Saving checkpoint... 
Iteration: 535659203, states[0] = -41.279913, states[40]= 0.000704
Saving checkpoint... 
Iteration: 544219275, states[0] = -94.000174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553327142, states[0] = -93.995985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562124261, states[0] = -94.004113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571129253, states[0] = -94.003868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580176083, states[0] = -94.001842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589015173, states[0] = -94.008850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598057441, states[0] = -94.006941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606980153, states[0] = -94.010336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615860505, states[0] = -94.015040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624600356, states[0] = -94.008100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633399008, states[0] = -93.907366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642450849, states[0] = -93.953912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650827370, states[0] = -93.995666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659744764, states[0] = -93.998785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668664797, states[0] = -94.002035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677500550, states[0] = -94.009216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686419115, states[0] = -94.012656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695324260, states[0] = -94.015847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703961980, states[0] = -93.961024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712959524, states[0] = -93.959449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721641578, states[0] = -27.468953, states[40]= 0.002194
Saving checkpoint... 
Iteration: 730594814, states[0] = 6.272504, states[40]= 0.002946
Saving checkpoint... 
Iteration: 739324347, states[0] = -93.995495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748200621, states[0] = -94.000286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756865536, states[0] = -94.014425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765242015, states[0] = -93.477686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774333378, states[0] = -93.801422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782895996, states[0] = -93.992823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791938361, states[0] = -93.991385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800548264, states[0] = -94.006704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808956282, states[0] = -93.957046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817754013, states[0] = -93.536292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826618877, states[0] = -8.946418, states[40]= 0.002659
Saving checkpoint... 
Iteration: 835568444, states[0] = 17.628504, states[40]= 0.000990
Saving checkpoint... 
Iteration: 844676367, states[0] = -55.389585, states[40]= 0.000096
Saving checkpoint... 
Iteration: 853277152, states[0] = -93.996904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862254988, states[0] = -93.997736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871088011, states[0] = -94.004716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880111120, states[0] = -94.003672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888917668, states[0] = -94.012070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897265982, states[0] = -93.589624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906266715, states[0] = -93.592710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914795012, states[0] = -93.996027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923801782, states[0] = -93.995744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932133262, states[0] = -94.011176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940803493, states[0] = -93.724331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949761515, states[0] = -93.570044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958691841, states[0] = -69.168036, states[40]= 0.000010
Saving checkpoint... 
Iteration: 967720365, states[0] = -93.135389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976640215, states[0] = -26.415618, states[40]= 0.002195
Saving checkpoint... 
Iteration: 985670366, states[0] = -50.421606, states[40]= 0.000204
Saving checkpoint... 
Iteration: 994587642, states[0] = 9.649884, states[40]= 0.002336
Saving checkpoint... 
Iteration: 1003183371, states[0] = -94.000189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011980916, states[0] = -94.009014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020863209, states[0] = -94.013662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029838564, states[0] = -94.014397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038512384, states[0] = -93.984754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047267351, states[0] = -93.594937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056238236, states[0] = -93.456568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064705106, states[0] = -93.999094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073792756, states[0] = -93.995606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082497867, states[0] = -94.008045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091282413, states[0] = -94.015397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100073517, states[0] = -94.001891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108651753, states[0] = -35.364930, states[40]= 0.001363
Saving checkpoint... 
Iteration: 1117635689, states[0] = -22.892024, states[40]= 0.001950
Saving checkpoint... 
Iteration: 1126563242, states[0] = 19.608585, states[40]= 0.000753
Saving checkpoint... 
Iteration: 1135461563, states[0] = -93.989545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144217193, states[0] = -93.998347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153160692, states[0] = -94.000666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161633461, states[0] = -94.010466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170537414, states[0] = -93.992760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179415663, states[0] = -93.923193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188125041, states[0] = -14.115878, states[40]= 0.001845
Saving checkpoint... 
Iteration: 1196980550, states[0] = -93.988753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205422927, states[0] = -94.010851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214129517, states[0] = -94.009898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223027936, states[0] = -93.989649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231463051, states[0] = -93.989191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240358010, states[0] = -93.992684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249236482, states[0] = -93.997236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258368667, states[0] = -93.992251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266680930, states[0] = -94.013521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275710473, states[0] = -94.014533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284643281, states[0] = -94.010985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293313248, states[0] = -93.750780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302180702, states[0] = -59.010362, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1310957052, states[0] = -93.989128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319873614, states[0] = -93.991882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328745584, states[0] = -93.996620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337632475, states[0] = -94.001286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346414182, states[0] = -94.010752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355297864, states[0] = -94.014320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364212800, states[0] = -94.014306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373049884, states[0] = -93.995579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381213986, states[0] = -93.997722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388758544, states[0] = -93.995919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396006611, states[0] = -94.006660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403517681, states[0] = -94.006145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411085761, states[0] = -94.003095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418852217, states[0] = -93.992321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426418904, states[0] = -93.990001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434216927, states[0] = -92.774016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441761275, states[0] = -93.567373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449377669, states[0] = -93.877637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456971631, states[0] = -93.964355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464106823, states[0] = -0.296873, states[40]= 0.003604
Saving checkpoint... 
Iteration: 1471157101, states[0] = -93.999805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478843445, states[0] = -93.992443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486544061, states[0] = 26.285822, states[40]= 0.000254
Saving checkpoint... 
Iteration: 1494053872, states[0] = 23.007323, states[40]= 0.000446
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.863147
 - CaMKt in component CaMK (millimolar): 0.003107
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 6.746530
 - nass in component intracellular_ions (millimolar): 6.746651
 - ki in component intracellular_ions (millimolar): 145.106250
 - kss in component intracellular_ions (millimolar): 145.106238
 - cansr in component intracellular_ions (millimolar): 1.832712
 - cajsr in component intracellular_ions (millimolar): 1.832540
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.004018
 - hf in component INa (dimensionless): 0.860776
 - hs in component INa (dimensionless): 0.860778
 - j in component INa (dimensionless): 0.860785
 - hsp in component INa (dimensionless): 0.690628
 - jp in component INa (dimensionless): 0.860789
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.701007
 - hLp in component INaL (dimensionless): 0.502734
 - a in component Ito (dimensionless): 0.000669
 - iF in component Ito (dimensionless): 0.999844
 - iS in component Ito (dimensionless): 0.968827
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999844
 - iSp in component Ito (dimensionless): 0.984202
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990184
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004996
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.030049
 - xs1 in component IKs (dimensionless): 0.072469
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997597
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:30:20 (25295): called boinc_finish(0)

</stderr_txt>
]]>


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