𝕏

Task 55553836

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_855_1
Workunit 26377947
Created 1 Jul 2024, 15:10:52 UTC
Sent 1 Jul 2024, 20:41:13 UTC
Report deadline 4 Jul 2024, 20:41:13 UTC
Received 3 Jul 2024, 22:23:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 54573
Run time 2 hours 24 min 51 sec
CPU time 2 hours 12 min 13 sec
Validate state Valid
Credit 43.58
Device peak FLOPS 3.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.74 MB
Peak swap size 4.10 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_855.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_855_1_r906674223_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_855_1_r906674223_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.818481
     * GNaL_b in INaL: 0.005714
     * Gto_b in Ito: 0.084049
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031658
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.161360
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.020198
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029570
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7195302, states[0] = -86.903983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18514185, states[0] = 22.134831, states[40]= 0.018223
Saving checkpoint... 
Iteration: 29697689, states[0] = -86.786834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41208733, states[0] = -86.782031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52825323, states[0] = -86.907529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63996926, states[0] = -86.951196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75202684, states[0] = -86.731137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86500747, states[0] = 38.969172, states[40]= 0.016447
Saving checkpoint... 
Iteration: 97493417, states[0] = -86.932308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108777616, states[0] = -86.833635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119759925, states[0] = -86.810833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130986701, states[0] = -86.924614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141757635, states[0] = -86.805166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153278803, states[0] = -86.829151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164723890, states[0] = -86.751994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176131215, states[0] = -53.281378, states[40]= 0.000014
Saving checkpoint... 
Iteration: 187506824, states[0] = 24.499486, states[40]= 0.099299
Saving checkpoint... 
Iteration: 198808384, states[0] = -86.854565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210263539, states[0] = -86.809986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221267292, states[0] = -86.814390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232586322, states[0] = -8.179895, states[40]= 0.002673
Saving checkpoint... 
Iteration: 242620761, states[0] = -42.181333, states[40]= 0.000084
Saving checkpoint... 
Iteration: 249710559, states[0] = -86.725705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260162549, states[0] = -85.990276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271644408, states[0] = -69.051787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 282877771, states[0] = -86.893509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294051178, states[0] = 11.288264, states[40]= 0.004764
Saving checkpoint... 
Iteration: 305574251, states[0] = 0.403013, states[40]= 0.004207
Saving checkpoint... 
Iteration: 311845715, states[0] = -86.878464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322429689, states[0] = -86.909788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332653598, states[0] = -81.206993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342542695, states[0] = 14.678358, states[40]= 0.004860


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_855.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_855_1_r906674223_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_855_1_r906674223_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.818481
     * GNaL_b in INaL: 0.005714
     * Gto_b in Ito: 0.084049
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031658
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.161360
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.020198
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029570
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 342542695
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 14.678358 (After loading)
 - states[40]: 0.004860 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 349071003, states[0] = 2.214417, states[40]= 0.004397
Saving checkpoint... 
Iteration: 358769211, states[0] = -86.816250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368694733, states[0] = -86.693510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378544631, states[0] = 13.919988, states[40]= 0.004826
Saving checkpoint... 
Iteration: 388622313, states[0] = -43.770874, states[40]= 0.000066
Saving checkpoint... 
Iteration: 398332015, states[0] = -86.870408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404436461, states[0] = -86.911309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410657998, states[0] = -84.564179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421682193, states[0] = -86.665051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431902166, states[0] = -86.902043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442816785, states[0] = -86.860156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453639928, states[0] = -63.246650, states[40]= 0.000003
Saving checkpoint... 
Iteration: 464525312, states[0] = 20.644765, states[40]= 0.006297
Saving checkpoint... 
Iteration: 475015672, states[0] = 22.622346, states[40]= 0.014258
Saving checkpoint... 
Iteration: 485658813, states[0] = -84.938905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496147176, states[0] = -72.885069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506610793, states[0] = -32.140255, states[40]= 0.000337
Saving checkpoint... 
Iteration: 517327474, states[0] = -86.867434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528081435, states[0] = -4.274784, states[40]= 0.003473
Saving checkpoint... 
Iteration: 538769635, states[0] = -86.816608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549534237, states[0] = 17.828011, states[40]= 0.005191
Saving checkpoint... 
Iteration: 560098932, states[0] = -20.297314, states[40]= 0.000904
Saving checkpoint... 
Iteration: 570733180, states[0] = -86.765999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581592579, states[0] = -13.975521, states[40]= 0.001585
Saving checkpoint... 
Iteration: 592480711, states[0] = -86.919368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603363980, states[0] = -86.887345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614165214, states[0] = -86.322021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624721792, states[0] = -86.746374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635350344, states[0] = -86.880677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646062782, states[0] = 6.277991, states[40]= 0.004654
Saving checkpoint... 
Iteration: 656463540, states[0] = -86.916556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667206343, states[0] = -86.716975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677812560, states[0] = -86.856871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688518523, states[0] = 22.182000, states[40]= 0.009784
Saving checkpoint... 
Iteration: 699391494, states[0] = -86.898301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709619223, states[0] = -40.603114, states[40]= 0.000107
Saving checkpoint... 
Iteration: 720629318, states[0] = -51.162299, states[40]= 0.000020
Saving checkpoint... 
Iteration: 731556371, states[0] = 9.116959, states[40]= 0.004732
Saving checkpoint... 
Iteration: 742504422, states[0] = 27.922572, states[40]= 0.156133
Saving checkpoint... 
Iteration: 753177965, states[0] = -86.649993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763813240, states[0] = -86.857321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774223985, states[0] = -86.750183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784948428, states[0] = -86.913613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791020664, states[0] = 21.768513, states[40]= 0.008061
Saving checkpoint... 
Iteration: 799479358, states[0] = -86.919021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807256536, states[0] = -86.800248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815606980, states[0] = -28.337201, states[40]= 0.000499
Saving checkpoint... 
Iteration: 824401578, states[0] = -86.901578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832739679, states[0] = -86.776154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841323734, states[0] = -86.864726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843652273, states[0] = -79.727674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850803652, states[0] = -86.849730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857896526, states[0] = -86.899909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863748742, states[0] = -86.789556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872005179, states[0] = 26.368400, states[40]= 0.139806
Saving checkpoint... 
Iteration: 880464706, states[0] = -86.916601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888952528, states[0] = -86.914355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897504001, states[0] = 29.083818, states[40]= 0.162097
Saving checkpoint... 
Iteration: 906071417, states[0] = 1.991999, states[40]= 0.004376
Saving checkpoint... 
Iteration: 914828967, states[0] = -86.868116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923466523, states[0] = -86.916882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932157683, states[0] = -84.400203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941297187, states[0] = -86.844169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950376972, states[0] = -86.892668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960054783, states[0] = 9.791003, states[40]= 0.004743
Saving checkpoint... 
Iteration: 969258101, states[0] = -86.802176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979353213, states[0] = -86.881905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989277768, states[0] = -86.825319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998830730, states[0] = -86.869176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008915381, states[0] = -86.905560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018833167, states[0] = -86.870679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028944086, states[0] = -86.912541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038711090, states[0] = -86.726042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048527005, states[0] = 20.168594, states[40]= 0.005962
Saving checkpoint... 
Iteration: 1059249919, states[0] = -86.791077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070162103, states[0] = -85.907036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080957027, states[0] = -86.915078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091528200, states[0] = 19.813809, states[40]= 0.005775
Saving checkpoint... 
Iteration: 1102215626, states[0] = -86.734670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112989812, states[0] = -86.920286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123553734, states[0] = 10.231229, states[40]= 0.004749
Saving checkpoint... 
Iteration: 1134486979, states[0] = -86.919883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145220017, states[0] = -86.742784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155750783, states[0] = -86.792215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166814595, states[0] = -86.858042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177573133, states[0] = 1.044388, states[40]= 0.004280
Saving checkpoint... 
Iteration: 1187941713, states[0] = -86.911921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198703286, states[0] = -86.710464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209541180, states[0] = 15.264349, states[40]= 0.004895
Saving checkpoint... 
Iteration: 1219432822, states[0] = -86.909889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230028311, states[0] = 19.780156, states[40]= 0.005760
Saving checkpoint... 
Iteration: 1240804738, states[0] = -86.850343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251234652, states[0] = -86.767909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261708364, states[0] = -86.720553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272518796, states[0] = 22.133342, states[40]= 0.009508
Saving checkpoint... 
Iteration: 1283148180, states[0] = -74.295624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294140971, states[0] = -64.545350, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1304895080, states[0] = -86.899107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315907578, states[0] = -86.903085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326473985, states[0] = -86.917822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337218688, states[0] = -86.740209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348123949, states[0] = -45.468691, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1358667202, states[0] = -86.456140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369260628, states[0] = -86.805125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380112653, states[0] = -33.995552, states[40]= 0.000269
Saving checkpoint... 
Iteration: 1390988086, states[0] = -86.919855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401791630, states[0] = -86.838825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412327961, states[0] = -86.867115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422431913, states[0] = -86.909530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423248244, states[0] = -86.788449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431843619, states[0] = -86.876498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434818552, states[0] = -86.860718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443521337, states[0] = 21.624377, states[40]= 0.007682
Saving checkpoint... 
Iteration: 1452011453, states[0] = 23.112632, states[40]= 0.032632
Saving checkpoint... 
Iteration: 1458146315, states[0] = -71.674629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467269175, states[0] = -86.815414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476674524, states[0] = -86.627907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486303931, states[0] = -86.849509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495890317, states[0] = -86.897323, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.797195
 - CaMKt in component CaMK (millimolar): 0.006756
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.398674
 - nass in component intracellular_ions (millimolar): 6.398731
 - ki in component intracellular_ions (millimolar): 145.585057
 - kss in component intracellular_ions (millimolar): 145.585038
 - cansr in component intracellular_ions (millimolar): 1.294221
 - cajsr in component intracellular_ions (millimolar): 1.256493
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008187
 - hf in component INa (dimensionless): 0.659428
 - hs in component INa (dimensionless): 0.659417
 - j in component INa (dimensionless): 0.659352
 - hsp in component INa (dimensionless): 0.411408
 - jp in component INa (dimensionless): 0.659307
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.464622
 - hLp in component INaL (dimensionless): 0.239671
 - a in component Ito (dimensionless): 0.001077
 - iF in component Ito (dimensionless): 0.999461
 - iS in component Ito (dimensionless): 0.578302
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999461
 - iSp in component Ito (dimensionless): 0.632730
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935506
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999893
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001530
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.408437
 - xs1 in component IKs (dimensionless): 0.241547
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997032
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:23:36 (74038): called boinc_finish(0)

</stderr_txt>
]]>


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