𝕏

Task 55553463

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_355_0
Workunit 26377761
Created 1 Jul 2024, 15:10:42 UTC
Sent 1 Jul 2024, 20:44:54 UTC
Report deadline 4 Jul 2024, 20:44:54 UTC
Received 2 Jul 2024, 19:44:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232190
Run time 2 hours 18 min 40 sec
CPU time 2 hours 16 min 6 sec
Validate state Valid
Credit 42.97
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.68 MB
Peak swap size 4.08 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_355.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_355_0_r918853449_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_355_0_r918853449_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.152059
     * GNaL_b in INaL: 0.005528
     * Gto_b in Ito: 0.083530
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032014
     * GKs_b in IKs: 0.001929
     * GK1_b in IK1: 0.167871
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.744415
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031833
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11333022, states[0] = -94.186303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22632836, states[0] = -22.112094, states[40]= 0.001718
Saving checkpoint... 
Iteration: 33975384, states[0] = -94.092753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45308524, states[0] = -93.828494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56660112, states[0] = -94.073053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68008212, states[0] = -94.053966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79307439, states[0] = -94.065844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90648281, states[0] = -94.081135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102004849, states[0] = 32.254096, states[40]= 0.349138
Saving checkpoint... 
Iteration: 113342737, states[0] = -94.083205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124675294, states[0] = -55.158470, states[40]= 0.000100
Saving checkpoint... 
Iteration: 135993073, states[0] = -94.077707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147316479, states[0] = -93.841181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158647462, states[0] = -94.071285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169983381, states[0] = -94.042263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181326428, states[0] = -94.064535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192636541, states[0] = -94.079668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203994676, states[0] = -94.059167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215344449, states[0] = -94.082790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226697124, states[0] = -76.739776, states[40]= 0.000003
Saving checkpoint... 
Iteration: 238044468, states[0] = -94.075244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249402419, states[0] = -93.982947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260720117, states[0] = -94.068123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272063208, states[0] = -94.068576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283403704, states[0] = -94.061662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294747466, states[0] = -94.083892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306101677, states[0] = 2.369786, states[40]= 0.003588
Saving checkpoint... 
Iteration: 317446003, states[0] = -94.079003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328809285, states[0] = -93.822165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340153685, states[0] = -94.070459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351484545, states[0] = -94.042247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362834325, states[0] = -94.063694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374158688, states[0] = -94.080852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385519430, states[0] = 31.584720, states[40]= 0.002295
Saving checkpoint... 
Iteration: 396840042, states[0] = -94.082341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408108653, states[0] = -1.871594, states[40]= 0.003679
Saving checkpoint... 
Iteration: 419446909, states[0] = -94.078651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430782014, states[0] = -93.738434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442056983, states[0] = -94.074089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453387982, states[0] = -93.966027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464681489, states[0] = -94.068974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476002828, states[0] = -94.049843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487309543, states[0] = -94.064160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498560367, states[0] = -94.067247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509822583, states[0] = -94.063638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521137738, states[0] = -94.078752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532462209, states[0] = -94.059090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543798416, states[0] = -94.082772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555101174, states[0] = 2.651943, states[40]= 0.003562
Saving checkpoint... 
Iteration: 566415279, states[0] = -94.079394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577762067, states[0] = -93.661264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589075491, states[0] = -94.072866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600375053, states[0] = -93.948906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611695657, states[0] = -94.067966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622988916, states[0] = -94.043441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634338113, states[0] = -94.062720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645656695, states[0] = -94.079873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656928455, states[0] = -94.059725, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_355.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_355_0_r918853449_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_3000-conf_355_0_r918853449_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.152059
     * GNaL_b in INaL: 0.005528
     * Gto_b in Ito: 0.083530
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032014
     * GKs_b in IKs: 0.001929
     * GK1_b in IK1: 0.167871
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.744415
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031833
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 656928455
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.059725 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 668191812, states[0] = -94.081653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679465930, states[0] = -94.058521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690721101, states[0] = -94.082385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701988893, states[0] = -94.057779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713265464, states[0] = -94.082585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724604826, states[0] = 0.539603, states[40]= 0.003697
Saving checkpoint... 
Iteration: 735874077, states[0] = -94.080291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747187783, states[0] = -66.155712, states[40]= 0.000017
Saving checkpoint... 
Iteration: 758511129, states[0] = -94.075005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769780830, states[0] = -93.733197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781078898, states[0] = -94.072128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792368587, states[0] = -93.939143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803644074, states[0] = -94.069401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814929129, states[0] = -94.005912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826225813, states[0] = -94.066147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837504974, states[0] = -94.049566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848790180, states[0] = -94.063717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860049021, states[0] = -94.063434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871350385, states[0] = -94.061568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882679550, states[0] = -94.080464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893996017, states[0] = -94.056976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905246571, states[0] = -94.081992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916520191, states[0] = 31.539398, states[40]= 0.001782
Saving checkpoint... 
Iteration: 927825682, states[0] = -94.081045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939129183, states[0] = -18.230343, states[40]= 0.001644
Saving checkpoint... 
Iteration: 950431030, states[0] = -94.077612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961722521, states[0] = -93.408531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973010268, states[0] = -94.074373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984311200, states[0] = -93.825134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995589697, states[0] = -94.071016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006875199, states[0] = -93.947833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018140939, states[0] = -94.068860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029453099, states[0] = -94.022629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040738996, states[0] = -94.064985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052020695, states[0] = -94.054589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063294442, states[0] = -94.062898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074541044, states[0] = -94.060678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085778766, states[0] = -94.063388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097059174, states[0] = -94.065118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108321133, states[0] = -94.061825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119595406, states[0] = -94.071833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130904376, states[0] = -94.059002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142169580, states[0] = -94.079139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153461430, states[0] = -94.057179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164757497, states[0] = -94.081203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176032864, states[0] = 29.372011, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1187285765, states[0] = -94.080948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198565290, states[0] = 18.680618, states[40]= 0.000929
Saving checkpoint... 
Iteration: 1209830668, states[0] = -94.080051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221129733, states[0] = -18.686318, states[40]= 0.001651
Saving checkpoint... 
Iteration: 1232383358, states[0] = -94.078445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243667893, states[0] = -49.015617, states[40]= 0.000253
Saving checkpoint... 
Iteration: 1254960539, states[0] = -94.075516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266253949, states[0] = -93.623804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277516839, states[0] = -94.073155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288814565, states[0] = -93.832792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300128825, states[0] = -94.068471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311411118, states[0] = -93.988394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322672342, states[0] = -94.066663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333979494, states[0] = -94.036721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345246444, states[0] = -94.063760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356524249, states[0] = -94.054810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367758449, states[0] = -94.063248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379017005, states[0] = -94.052314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390311180, states[0] = -94.061292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401570908, states[0] = -94.066667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412853718, states[0] = -94.059771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424156400, states[0] = -94.077434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435458583, states[0] = -94.056386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446737801, states[0] = -94.080254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458022059, states[0] = 31.374685, states[40]= 0.000976
Saving checkpoint... 
Iteration: 1469292405, states[0] = -94.079986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480568512, states[0] = 17.440721, states[40]= 0.001095
Saving checkpoint... 
Iteration: 1491866760, states[0] = -94.078172, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.930933
 - CaMKt in component CaMK (millimolar): 0.003103
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 6.761343
 - nass in component intracellular_ions (millimolar): 6.761464
 - ki in component intracellular_ions (millimolar): 145.091754
 - kss in component intracellular_ions (millimolar): 145.091743
 - cansr in component intracellular_ions (millimolar): 1.833523
 - cajsr in component intracellular_ions (millimolar): 1.833343
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.003991
 - hf in component INa (dimensionless): 0.862106
 - hs in component INa (dimensionless): 0.862107
 - j in component INa (dimensionless): 0.862114
 - hsp in component INa (dimensionless): 0.693002
 - jp in component INa (dimensionless): 0.862118
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.702895
 - hLp in component INaL (dimensionless): 0.505003
 - a in component Ito (dimensionless): 0.000666
 - iF in component Ito (dimensionless): 0.999846
 - iS in component Ito (dimensionless): 0.969034
 - ap in component Ito (dimensionless): 0.000339
 - iFp in component Ito (dimensionless): 0.999846
 - iSp in component Ito (dimensionless): 0.984369
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990251
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005004
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.029686
 - xs1 in component IKs (dimensionless): 0.072063
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997581
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:44:17 (72542): called boinc_finish(0)

</stderr_txt>
]]>


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