𝕏

Task 55552136

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_EPI-conf_354_1
Workunit 26377101
Created 1 Jul 2024, 15:10:05 UTC
Sent 1 Jul 2024, 20:31:29 UTC
Report deadline 4 Jul 2024, 20:31:29 UTC
Received 3 Jul 2024, 10:29:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 6 min 58 sec
CPU time 1 hours 31 min
Validate state Valid
Credit 44.04
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.72 MB
Peak swap size 3.88 MB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_EPI-conf_354.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_EPI-conf_354_1_r1102468720_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_EPI-conf_354_1_r1102468720_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 100.983462
     * GNaL_b in INaL: 0.006044
     * Gto_b in Ito: 0.081319
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031453
     * GKs_b in IKs: 0.001971
     * GK1_b in IK1: 0.165155
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.125794
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030553
     * celltype in environment: 1.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6908447, states[0] = -87.099041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15289112, states[0] = -86.967118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23478636, states[0] = -87.103622, states[40]= 0.000001
Saving checkpoint... 
Iteration: 32442241, states[0] = -87.108436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 41311113, states[0] = -87.028937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49985018, states[0] = -87.137905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 58223477, states[0] = -86.804811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66303140, states[0] = -87.037987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74184702, states[0] = -86.573480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82524492, states[0] = 19.536504, states[40]= 0.000085
Saving checkpoint... 
Iteration: 90565973, states[0] = 11.490874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98200002, states[0] = -86.690163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105136808, states[0] = -53.973663, states[40]= 0.000002
Saving checkpoint... 
Iteration: 113123508, states[0] = -37.790039, states[40]= 0.000011
Saving checkpoint... 
Iteration: 120781116, states[0] = -87.010651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128021466, states[0] = 19.292977, states[40]= 0.000275
Saving checkpoint... 
Iteration: 136677293, states[0] = -86.518737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145374726, states[0] = -87.126103, states[40]= 0.000001
Saving checkpoint... 
Iteration: 153592227, states[0] = -3.887460, states[40]= 0.000010
Saving checkpoint... 
Iteration: 161443230, states[0] = -87.155377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169925258, states[0] = -87.149887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179904050, states[0] = -87.141532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 187008358, states[0] = 15.647732, states[40]= 0.140298
Saving checkpoint... 
Iteration: 194622726, states[0] = -37.035095, states[40]= 0.000011
Saving checkpoint... 
Iteration: 201078341, states[0] = 5.462456, states[40]= 0.000003
Saving checkpoint... 
Iteration: 210206288, states[0] = -86.731948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218582465, states[0] = 3.068901, states[40]= 0.000004
Saving checkpoint... 
Iteration: 226901428, states[0] = -87.139256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 236195746, states[0] = -86.663676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244917814, states[0] = -87.145505, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252903050, states[0] = -87.139258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 260913158, states[0] = -87.143268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 270131571, states[0] = -47.657422, states[40]= 0.000005
Saving checkpoint... 
Iteration: 279364306, states[0] = -87.116232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 287428716, states[0] = -87.148048, states[40]= 0.000001
Saving checkpoint... 
Iteration: 295582801, states[0] = 2.861620, states[40]= 0.000004
Saving checkpoint... 
Iteration: 303636107, states[0] = -53.319913, states[40]= 0.000003
Saving checkpoint... 
Iteration: 311220769, states[0] = -86.807555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319068360, states[0] = 10.364383, states[40]= 0.000001
Saving checkpoint... 
Iteration: 327339656, states[0] = -87.093877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 335265315, states[0] = -86.969548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343259618, states[0] = -86.953674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350577417, states[0] = 5.964387, states[40]= 0.000002
Saving checkpoint... 
Iteration: 357938104, states[0] = -87.148815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 364671874, states[0] = -86.440901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373042553, states[0] = 18.437141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382172676, states[0] = -86.454593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389572610, states[0] = 8.414260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398520528, states[0] = 19.201735, states[40]= 0.000400
Saving checkpoint... 
Iteration: 406018027, states[0] = 18.925761, states[40]= 0.001178
Saving checkpoint... 
Iteration: 413359114, states[0] = -87.108363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421542764, states[0] = 18.401615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429931812, states[0] = -87.144798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437394365, states[0] = -87.129697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444935471, states[0] = -87.145461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452253927, states[0] = -86.933492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459703700, states[0] = -86.708730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467589867, states[0] = -2.001680, states[40]= 0.000009
Saving checkpoint... 
Iteration: 476084052, states[0] = 2.078575, states[40]= 0.000005
Saving checkpoint... 
Iteration: 483722075, states[0] = -86.808666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492146521, states[0] = -67.610281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499825084, states[0] = -87.072897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 507303508, states[0] = -87.043016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514751874, states[0] = -86.925176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522051111, states[0] = 16.548161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529814602, states[0] = -87.058629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537754332, states[0] = -86.932163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546664985, states[0] = -86.105757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554450546, states[0] = -87.146255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562523496, states[0] = 19.431498, states[40]= 0.000117
Saving checkpoint... 
Iteration: 570075957, states[0] = 6.740459, states[40]= 0.000002
Saving checkpoint... 
Iteration: 578785482, states[0] = -87.008746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587391734, states[0] = -87.123898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595363408, states[0] = -87.106170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603099182, states[0] = -10.557346, states[40]= 0.000012
Saving checkpoint... 
Iteration: 610703675, states[0] = -86.703960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618426742, states[0] = -87.137563, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627234748, states[0] = -86.860285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635074995, states[0] = 7.236427, states[40]= 0.000002
Saving checkpoint... 
Iteration: 643633283, states[0] = -49.765478, states[40]= 0.000004
Saving checkpoint... 
Iteration: 651363331, states[0] = -87.104443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659559039, states[0] = 14.047204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667783705, states[0] = -87.002469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675909316, states[0] = -87.129389, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683796376, states[0] = -87.025930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691931546, states[0] = -87.136919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699720258, states[0] = -86.793236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707674259, states[0] = -86.467862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715654639, states[0] = -80.321624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723910974, states[0] = -87.128638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 732230446, states[0] = -86.839199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740431269, states[0] = -87.135390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 749135204, states[0] = -52.164103, states[40]= 0.000003
Saving checkpoint... 
Iteration: 757764407, states[0] = -86.954428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765726940, states[0] = -86.822772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774042146, states[0] = 18.508930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783132134, states[0] = -48.336011, states[40]= 0.000004
Saving checkpoint... 
Iteration: 791666095, states[0] = -86.197782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800868367, states[0] = -87.103568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 808453211, states[0] = -87.139336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 816443432, states[0] = -87.136648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 824229311, states[0] = -86.831503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833067831, states[0] = 10.600347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842201690, states[0] = -86.684430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850034720, states[0] = 19.386456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857562964, states[0] = 12.590248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865293027, states[0] = -87.014552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873742470, states[0] = -86.882392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881498068, states[0] = -87.144988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 889942253, states[0] = -87.134144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897609823, states[0] = -22.378636, states[40]= 0.000012
Saving checkpoint... 
Iteration: 904573866, states[0] = 7.807105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 912678828, states[0] = -86.511355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920854889, states[0] = -87.089870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 929005724, states[0] = 12.275582, states[40]= 0.417863
Saving checkpoint... 
Iteration: 936584267, states[0] = 1.948478, states[40]= 0.000005
Saving checkpoint... 
Iteration: 944030172, states[0] = 19.586098, states[40]= 0.000008
Saving checkpoint... 
Iteration: 952680704, states[0] = -86.527032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960827100, states[0] = -87.061493, states[40]= 0.000001
Saving checkpoint... 
Iteration: 969584536, states[0] = 1.775366, states[40]= 0.000005
Saving checkpoint... 
Iteration: 977475813, states[0] = -87.138873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 985391997, states[0] = -87.112178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 993504081, states[0] = 10.704030, states[40]= 0.757663
Saving checkpoint... 
Iteration: 1002240422, states[0] = -86.870973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010780814, states[0] = -86.986116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019548208, states[0] = 17.292147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026929438, states[0] = -87.126285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035867048, states[0] = -87.095646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044364670, states[0] = -87.093700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1051730555, states[0] = -86.829983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059624818, states[0] = -39.475672, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1068020315, states[0] = 19.185945, states[40]= 0.000441
Saving checkpoint... 
Iteration: 1076209212, states[0] = -86.722797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084258337, states[0] = -86.927668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092421813, states[0] = -87.121770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1100111958, states[0] = -24.765887, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1108562554, states[0] = 12.751181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115186441, states[0] = -86.568908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123589979, states[0] = -2.074793, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1131267873, states[0] = -86.952244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139066123, states[0] = 11.327185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146859939, states[0] = -87.087123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155917677, states[0] = -87.118380, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1164202212, states[0] = -86.677888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172187000, states[0] = -86.571474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181556137, states[0] = 15.048631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190022081, states[0] = 19.339419, states[40]= 0.000211
Saving checkpoint... 
Iteration: 1199269551, states[0] = -86.954430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206904825, states[0] = -87.111669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1214751214, states[0] = -86.901955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223518583, states[0] = 18.999867, states[40]= 0.000929
Saving checkpoint... 
Iteration: 1231634638, states[0] = -51.436129, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1240189653, states[0] = -86.589434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249581537, states[0] = 3.643456, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1258571112, states[0] = 9.134629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1266732621, states[0] = -86.832196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274517829, states[0] = 18.905527, states[40]= 0.001295
Saving checkpoint... 
Iteration: 1282274588, states[0] = -86.964071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289811135, states[0] = -87.031054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298001996, states[0] = 21.638832, states[40]= 1.500353
Saving checkpoint... 
Iteration: 1305667229, states[0] = -86.255293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312988727, states[0] = -87.130919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320563108, states[0] = 12.539808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328751454, states[0] = -86.899285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336865536, states[0] = -87.085601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344274934, states[0] = -86.963012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352443647, states[0] = -87.120758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360412471, states[0] = -87.110289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368473859, states[0] = -87.126904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1376578176, states[0] = 5.566476, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1384862222, states[0] = -87.081751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1393111082, states[0] = -23.775626, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1400869292, states[0] = -87.086315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408435210, states[0] = -87.116714, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1416205833, states[0] = -86.692523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424516023, states[0] = 18.639317, states[40]= 0.002936
Saving checkpoint... 
Iteration: 1432478149, states[0] = -87.125736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1441388519, states[0] = -87.096768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450048357, states[0] = 17.261106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458465632, states[0] = -87.122685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466467535, states[0] = -87.122820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474453960, states[0] = -87.119699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481019047, states[0] = 19.055623, states[40]= 0.000761
Saving checkpoint... 
Iteration: 1488841465, states[0] = -87.060974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496943839, states[0] = -87.116510, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.002707
 - CaMKt in component CaMK (millimolar): 0.018773
 - cass in component intracellular_ions (millimolar): 0.000080
 - nai in component intracellular_ions (millimolar): 7.286189
 - nass in component intracellular_ions (millimolar): 7.286291
 - ki in component intracellular_ions (millimolar): 144.294348
 - kss in component intracellular_ions (millimolar): 144.294313
 - cansr in component intracellular_ions (millimolar): 2.167600
 - cajsr in component intracellular_ions (millimolar): 2.110488
 - cai in component intracellular_ions (millimolar): 0.000082
 - m in component INa (dimensionless): 0.008019
 - hf in component INa (dimensionless): 0.666971
 - hs in component INa (dimensionless): 0.666959
 - j in component INa (dimensionless): 0.666889
 - hsp in component INa (dimensionless): 0.419607
 - jp in component INa (dimensionless): 0.666836
 - mL in component INaL (dimensionless): 0.000222
 - hL in component INaL (dimensionless): 0.470337
 - hLp in component INaL (dimensionless): 0.242409
 - a in component Ito (dimensionless): 0.001062
 - iF in component Ito (dimensionless): 0.999480
 - iS in component Ito (dimensionless): 0.999435
 - ap in component Ito (dimensionless): 0.000541
 - iFp in component Ito (dimensionless): 0.999480
 - iSp in component Ito (dimensionless): 0.999469
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.929308
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002178
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.359741
 - xs1 in component IKs (dimensionless): 0.266175
 - xs2 in component IKs (dimensionless): 0.000213
 - xk1 in component IK1 (dimensionless): 0.996982
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
11:14:54 (54491): called boinc_finish(0)

</stderr_txt>
]]>


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