𝕏

Task 55547894

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_250_0
Workunit 26375000
Created 1 Jul 2024, 15:08:05 UTC
Sent 1 Jul 2024, 20:02:37 UTC
Report deadline 4 Jul 2024, 22:55:25 UTC
Received 4 Jul 2024, 7:11:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222140
Run time 1 hours 22 min 16 sec
CPU time 55 min 34 sec
Validate state Valid
Credit 48.66
Device peak FLOPS 3.88 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.81 MB
Peak swap size 391.76 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_250.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_250_0_r453955440_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_250_0_r453955440_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 106.548613
     * GNaL_b in INaL: 0.005777
     * Gto_b in Ito: 0.081084
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031862
     * GKs_b in IKs: 0.001934
     * GK1_b in IK1: 0.159846
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.789137
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034731
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16538273, states[0] = 21.594108, states[40]= 0.002853
Saving checkpoint... 
Iteration: 31307333, states[0] = -94.744529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50034734, states[0] = 23.131095, states[40]= 0.002096
Saving checkpoint... 
Iteration: 64543770, states[0] = 19.865716, states[40]= 0.002665
Saving checkpoint... 
Iteration: 81706326, states[0] = -94.467062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95789317, states[0] = -94.701809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110770912, states[0] = -94.665598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120958879, states[0] = -94.839587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131560036, states[0] = 13.292440, states[40]= 0.003959
Saving checkpoint... 
Iteration: 142640927, states[0] = -53.571669, states[40]= 0.000052
Saving checkpoint... 
Iteration: 156321652, states[0] = -94.748391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167169271, states[0] = -90.118365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178978055, states[0] = -94.844156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189403149, states[0] = -94.816136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203208653, states[0] = -94.474460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213197894, states[0] = -94.427675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225836379, states[0] = -94.764838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236609371, states[0] = -22.238589, states[40]= 0.001241
Saving checkpoint... 
Iteration: 247522355, states[0] = 26.815284, states[40]= 0.002256
Saving checkpoint... 
Iteration: 256933184, states[0] = -94.829640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269894993, states[0] = -94.811230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280878075, states[0] = -94.800482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293201201, states[0] = -94.442408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305005079, states[0] = 31.553798, states[40]= 0.246620
Saving checkpoint... 
Iteration: 316102950, states[0] = -15.904000, states[40]= 0.001647
Saving checkpoint... 
Iteration: 328506493, states[0] = 29.549255, states[40]= 0.155641
Saving checkpoint... 
Iteration: 340280684, states[0] = -94.683837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351745719, states[0] = -94.601685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363291338, states[0] = -94.703113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372082768, states[0] = 1.370254, states[40]= 0.004782
Saving checkpoint... 
Iteration: 385107855, states[0] = -20.758168, states[40]= 0.001280
Saving checkpoint... 
Iteration: 397997426, states[0] = -94.847565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409170398, states[0] = -91.108265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420035998, states[0] = 22.746993, states[40]= 0.002169
Saving checkpoint... 
Iteration: 430856264, states[0] = -94.783081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442429846, states[0] = -94.827606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451067876, states[0] = 9.679454, states[40]= 0.004494
Saving checkpoint... 
Iteration: 463348146, states[0] = -94.775662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472726504, states[0] = -94.540898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480441923, states[0] = -94.832089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491869899, states[0] = -94.793817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500966636, states[0] = -94.839862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509649659, states[0] = -63.070229, states[40]= 0.000011
Saving checkpoint... 
Iteration: 519909638, states[0] = -94.818187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529127493, states[0] = -39.734060, states[40]= 0.000375
Saving checkpoint... 
Iteration: 539768638, states[0] = -94.658291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551896870, states[0] = -94.811254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561188615, states[0] = -94.368891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573140376, states[0] = -52.967583, states[40]= 0.000058
Saving checkpoint... 
Iteration: 587652336, states[0] = -66.211026, states[40]= 0.000007
Saving checkpoint... 
Iteration: 599945345, states[0] = -94.832855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608118296, states[0] = -30.816548, states[40]= 0.000933
Saving checkpoint... 
Iteration: 620530789, states[0] = 24.493176, states[40]= 0.001927
Saving checkpoint... 
Iteration: 632852136, states[0] = -94.778695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645610900, states[0] = -23.717822, states[40]= 0.001215
Saving checkpoint... 
Iteration: 657701352, states[0] = -94.441696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671661449, states[0] = -78.874536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 679591255, states[0] = -4.880472, states[40]= 0.003899
Saving checkpoint... 
Iteration: 691951280, states[0] = -94.834514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704154743, states[0] = -69.211027, states[40]= 0.000004
Saving checkpoint... 
Iteration: 717169111, states[0] = -89.943297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728853584, states[0] = -94.779631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738173410, states[0] = -92.869632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747245336, states[0] = -94.599115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761162303, states[0] = -80.239465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 771051274, states[0] = 16.975086, states[40]= 0.003258
Saving checkpoint... 
Iteration: 783403947, states[0] = -94.814280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795028388, states[0] = 25.231955, states[40]= 0.001868
Saving checkpoint... 
Iteration: 804197233, states[0] = -94.422260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818906843, states[0] = -94.815659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832785502, states[0] = -94.691032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842430766, states[0] = -94.826493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854476294, states[0] = -94.841110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864550048, states[0] = 17.465620, states[40]= 0.003159
Saving checkpoint... 
Iteration: 876572109, states[0] = 7.547064, states[40]= 0.004705
Saving checkpoint... 
Iteration: 888226564, states[0] = -94.539542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897464483, states[0] = -94.837784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906840081, states[0] = -94.766126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919280079, states[0] = -94.680503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931442371, states[0] = -94.830576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944807592, states[0] = -94.726485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956627036, states[0] = -39.281328, states[40]= 0.000396
Saving checkpoint... 
Iteration: 966166633, states[0] = -86.950198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975587408, states[0] = -1.850436, states[40]= 0.004448
Saving checkpoint... 
Iteration: 987240427, states[0] = -94.583894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999640161, states[0] = -52.738168, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1011640231, states[0] = -52.812085, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1023543517, states[0] = 19.999912, states[40]= 0.002656
Saving checkpoint... 
Iteration: 1035761493, states[0] = -94.640092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047622366, states[0] = -34.729399, states[40]= 0.000665
Saving checkpoint... 
Iteration: 1060870663, states[0] = -94.792272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073955743, states[0] = -94.834522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085247470, states[0] = -94.603838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095692627, states[0] = -94.396792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107340251, states[0] = -94.765552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117589821, states[0] = -3.708377, states[40]= 0.004134
Saving checkpoint... 
Iteration: 1129205703, states[0] = -94.458663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140655848, states[0] = -70.656947, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1151320650, states[0] = -94.743240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161990234, states[0] = -94.843231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172368247, states[0] = -94.790039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183902540, states[0] = -94.812042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196587388, states[0] = -1.835088, states[40]= 0.004450
Saving checkpoint... 
Iteration: 1208283738, states[0] = -94.686375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220180013, states[0] = -94.127452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232747568, states[0] = -94.603556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244172653, states[0] = -92.530172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253696279, states[0] = -94.415913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263153822, states[0] = -68.034774, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1274959642, states[0] = -94.834969, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_250.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_250_0_r453955440_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_250_0_r453955440_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 106.548613
     * GNaL_b in INaL: 0.005777
     * Gto_b in Ito: 0.081084
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031862
     * GKs_b in IKs: 0.001934
     * GK1_b in IK1: 0.159846
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.789137
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034731
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1274959642
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.834969 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1285787633, states[0] = -94.693187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294484577, states[0] = -94.841474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307800352, states[0] = -94.714305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316127970, states[0] = -40.203129, states[40]= 0.000353
Saving checkpoint... 
Iteration: 1326699078, states[0] = -94.428934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340313292, states[0] = -94.732961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349125892, states[0] = -38.155783, states[40]= 0.000454
Saving checkpoint... 
Iteration: 1358769289, states[0] = -94.656652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370122373, states[0] = -34.734990, states[40]= 0.000664
Saving checkpoint... 
Iteration: 1380943846, states[0] = -94.829432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390686281, states[0] = -94.338117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403246207, states[0] = -94.599116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413622590, states[0] = -34.944505, states[40]= 0.000650
Saving checkpoint... 
Iteration: 1422804090, states[0] = -94.719571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433972995, states[0] = -94.838115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445431214, states[0] = -94.824435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458824735, states[0] = -94.747095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470900084, states[0] = -94.809640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484228198, states[0] = -94.542914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496536807, states[0] = 22.463374, states[40]= 0.002216
Saving checkpoint... 
Iteration: 1509840282, states[0] = -21.298970, states[40]= 0.001643
Saving checkpoint... 
Iteration: 1520345291, states[0] = -16.797496, states[40]= 0.001795
Saving checkpoint... 
Iteration: 1530158261, states[0] = -94.837917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542175766, states[0] = -94.730168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554311235, states[0] = 13.979000, states[40]= 0.003458
Saving checkpoint... 
Iteration: 1565632032, states[0] = -94.620394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576384167, states[0] = -94.527890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589706497, states[0] = -94.513674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605435947, states[0] = -94.485121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617399881, states[0] = -94.476612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626612192, states[0] = -94.404759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637320264, states[0] = -94.389750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647875389, states[0] = -94.298053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659164170, states[0] = -94.383483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670452052, states[0] = -94.343829, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.246210
 - CaMKt in component CaMK (millimolar): 0.001127
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.398305
 - nass in component intracellular_ions (millimolar): 6.398391
 - ki in component intracellular_ions (millimolar): 145.499789
 - kss in component intracellular_ions (millimolar): 145.499778
 - cansr in component intracellular_ions (millimolar): 1.569120
 - cajsr in component intracellular_ions (millimolar): 1.569135
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003866
 - hf in component INa (dimensionless): 0.868149
 - hs in component INa (dimensionless): 0.868149
 - j in component INa (dimensionless): 0.868151
 - hsp in component INa (dimensionless): 0.703906
 - jp in component INa (dimensionless): 0.868151
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.711542
 - hLp in component INaL (dimensionless): 0.518649
 - a in component Ito (dimensionless): 0.000652
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.997745
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.999249
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998882
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003022
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001823
 - xs1 in component IKs (dimensionless): 0.022490
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997504
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:11:10 (77633): called boinc_finish(0)

</stderr_txt>
]]>


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