𝕏

Task 55547893

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_150_1
Workunit 26374999
Created 1 Jul 2024, 15:08:05 UTC
Sent 1 Jul 2024, 20:02:37 UTC
Report deadline 4 Jul 2024, 22:55:25 UTC
Received 2 Jul 2024, 18:09:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222140
Run time 1 hours 22 min 41 sec
CPU time 55 min 30 sec
Validate state Valid
Credit 47.94
Device peak FLOPS 3.88 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.50 MB
Peak swap size 391.76 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_150.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_150_1_r1349363616_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-CLVPET-conf_150_1_r1349363616_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.809845
     * GNaL_b in INaL: 0.005447
     * Gto_b in Ito: 0.083855
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031776
     * GKs_b in IKs: 0.001957
     * GK1_b in IK1: 0.166293
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.398157
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029135
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12060123, states[0] = 12.448033, states[40]= 0.004313
Saving checkpoint... 
Iteration: 27162599, states[0] = -84.723712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38583045, states[0] = 0.877554, states[40]= 0.004633
Saving checkpoint... 
Iteration: 49715710, states[0] = -94.577674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62191584, states[0] = -94.470661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74168437, states[0] = -90.661276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83498705, states[0] = -94.909402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95903873, states[0] = -94.877063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105065715, states[0] = 10.651443, states[40]= 0.004189
Saving checkpoint... 
Iteration: 120557254, states[0] = 14.431429, states[40]= 0.003550
Saving checkpoint... 
Iteration: 137481128, states[0] = -94.903402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152720778, states[0] = -94.587914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170337340, states[0] = -94.825939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186328617, states[0] = -94.816462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203495331, states[0] = -94.905814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219391648, states[0] = -94.868159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233730957, states[0] = -94.621982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249113901, states[0] = -26.761819, states[40]= 0.001121
Saving checkpoint... 
Iteration: 265963897, states[0] = -94.897987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285072768, states[0] = 7.171381, states[40]= 0.004588
Saving checkpoint... 
Iteration: 299654366, states[0] = -69.484820, states[40]= 0.000004
Saving checkpoint... 
Iteration: 316523005, states[0] = 26.486216, states[40]= 0.001991
Saving checkpoint... 
Iteration: 333735066, states[0] = -94.634553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351995890, states[0] = -94.905288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368844295, states[0] = -94.831854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385742060, states[0] = -94.655182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403207715, states[0] = -94.536767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418698862, states[0] = -94.499316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434822403, states[0] = -94.808189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448213014, states[0] = -94.557547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464583983, states[0] = 0.543689, states[40]= 0.004632
Saving checkpoint... 
Iteration: 479187160, states[0] = -94.432758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494739078, states[0] = -94.646067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510227290, states[0] = -94.608803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525301392, states[0] = -94.779660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545289220, states[0] = -94.760102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561336123, states[0] = -94.822992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578202661, states[0] = -94.515146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595675725, states[0] = -93.895721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615765868, states[0] = -94.714372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629867358, states[0] = -94.850382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647470582, states[0] = -94.898325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663937592, states[0] = -94.887951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680308801, states[0] = -94.789726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695650481, states[0] = -64.579703, states[40]= 0.000009
Saving checkpoint... 
Iteration: 710742912, states[0] = -94.656349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726341950, states[0] = -94.828214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742611451, states[0] = -24.388596, states[40]= 0.001181
Saving checkpoint... 
Iteration: 757395465, states[0] = -94.868240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773956973, states[0] = -94.894004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787300219, states[0] = -94.776879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800610119, states[0] = -23.093146, states[40]= 0.001204
Saving checkpoint... 
Iteration: 811583744, states[0] = 0.704763, states[40]= 0.004644
Saving checkpoint... 
Iteration: 824295309, states[0] = -94.769088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836431558, states[0] = -94.884996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848034299, states[0] = 23.221935, states[40]= 0.001912
Saving checkpoint... 
Iteration: 862981951, states[0] = -94.900308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873876239, states[0] = -94.855815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884388657, states[0] = -94.863774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896392466, states[0] = -94.865986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908445477, states[0] = -94.889801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921140154, states[0] = -53.083597, states[40]= 0.000056
Saving checkpoint... 
Iteration: 931223072, states[0] = -94.592695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941476792, states[0] = -94.898772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952973322, states[0] = -94.897859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963821771, states[0] = -94.805387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976270248, states[0] = -94.722411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989076581, states[0] = 5.094712, states[40]= 0.004711
Saving checkpoint... 
Iteration: 1001454791, states[0] = -94.892463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012277038, states[0] = -94.736033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025730279, states[0] = -94.616670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036435197, states[0] = -94.885625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045795554, states[0] = -94.768623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056934008, states[0] = -94.885095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068158677, states[0] = -75.706694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080680792, states[0] = -94.310362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091092544, states[0] = -6.016423, states[40]= 0.003602
Saving checkpoint... 
Iteration: 1101272528, states[0] = -94.726663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111736581, states[0] = -94.636169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123778891, states[0] = -94.739181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133572541, states[0] = 7.292065, states[40]= 0.004579
Saving checkpoint... 
Iteration: 1142920054, states[0] = -94.879038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151761027, states[0] = -94.701316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161980903, states[0] = -94.898912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172654682, states[0] = -69.901104, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1183578411, states[0] = 4.041019, states[40]= 0.004738
Saving checkpoint... 
Iteration: 1192339719, states[0] = -94.824215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202559357, states[0] = 13.543548, states[40]= 0.003723
Saving checkpoint... 
Iteration: 1214728612, states[0] = -94.610462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228617574, states[0] = -30.301462, states[40]= 0.000948
Saving checkpoint... 
Iteration: 1237637202, states[0] = -49.951871, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1249521426, states[0] = 26.820299, states[40]= 0.002347
Saving checkpoint... 
Iteration: 1262827659, states[0] = -94.811112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273488146, states[0] = -94.900125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285451280, states[0] = -94.890266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296566582, states[0] = 10.265890, states[40]= 0.004251
Saving checkpoint... 
Iteration: 1308461587, states[0] = -94.893309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323210700, states[0] = -94.545099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334810235, states[0] = -94.789165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347937924, states[0] = -94.885441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357665220, states[0] = -86.372534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368115461, states[0] = -28.262330, states[40]= 0.001060
Saving checkpoint... 
Iteration: 1379615741, states[0] = -28.532390, states[40]= 0.001047
Saving checkpoint... 
Iteration: 1391740350, states[0] = -94.646317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403265217, states[0] = -94.709874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414684326, states[0] = -94.395409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423031912, states[0] = 24.009031, states[40]= 0.001807
Saving checkpoint... 
Iteration: 1434302681, states[0] = -94.778062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447223236, states[0] = -94.591256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457497514, states[0] = -94.901359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466015360, states[0] = 27.652891, states[40]= 0.008922
Saving checkpoint... 
Iteration: 1476919821, states[0] = -94.877650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488933176, states[0] = -94.883113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499944636, states[0] = -94.887238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511496501, states[0] = -95.202619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525346865, states[0] = -11.536945, states[40]= 0.002374
Saving checkpoint... 
Iteration: 1536517506, states[0] = -94.601690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547892250, states[0] = -94.720670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559711034, states[0] = -94.699565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1569435556, states[0] = -94.638115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581208592, states[0] = -94.595706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590640518, states[0] = -36.376039, states[40]= 0.000648
Saving checkpoint... 
Iteration: 1602456284, states[0] = -94.561548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613532161, states[0] = -94.545539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622397828, states[0] = -94.480297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633052681, states[0] = -94.472994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642949373, states[0] = -94.433141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1654773779, states[0] = -94.459582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664065541, states[0] = -94.462487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674565223, states[0] = -94.454368, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.326439
 - CaMKt in component CaMK (millimolar): 0.001135
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.351333
 - nass in component intracellular_ions (millimolar): 6.351420
 - ki in component intracellular_ions (millimolar): 145.544350
 - kss in component intracellular_ions (millimolar): 145.544338
 - cansr in component intracellular_ions (millimolar): 1.574701
 - cajsr in component intracellular_ions (millimolar): 1.574713
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003835
 - hf in component INa (dimensionless): 0.869651
 - hs in component INa (dimensionless): 0.869651
 - j in component INa (dimensionless): 0.869652
 - hsp in component INa (dimensionless): 0.706646
 - jp in component INa (dimensionless): 0.869653
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.713736
 - hLp in component INaL (dimensionless): 0.521321
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997766
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999260
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998886
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003063
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001776
 - xs1 in component IKs (dimensionless): 0.022473
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997484
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:26:12 (49091): called boinc_finish(0)

</stderr_txt>
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