𝕏

Task 55546718

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_15-conf_448_0
Workunit 26374412
Created 1 Jul 2024, 15:07:32 UTC
Sent 1 Jul 2024, 19:54:26 UTC
Report deadline 4 Jul 2024, 19:54:26 UTC
Received 2 Jul 2024, 10:13:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222486
Run time 1 hours 56 min 35 sec
CPU time 1 hours 40 min 26 sec
Validate state Valid
Credit 42.08
Device peak FLOPS 3.26 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.21 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_15-conf_448.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_15-conf_448_0_r1199440500_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_15-conf_448_0_r1199440500_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.997984
     * GNaL_b in INaL: 0.006119
     * Gto_b in Ito: 0.083641
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.026732
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.161710
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.291386
     * GKb_b in IKb: 0.003827
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031175
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8356644, states[0] = -94.871720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16638422, states[0] = -39.283973, states[40]= 0.000443
Saving checkpoint... 
Iteration: 24946396, states[0] = -94.854628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33314938, states[0] = -94.744473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42019396, states[0] = 27.921178, states[40]= 0.003198
Saving checkpoint... 
Iteration: 50400372, states[0] = -94.815320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58397728, states[0] = -94.811863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66516372, states[0] = 28.285388, states[40]= 0.006638
Saving checkpoint... 
Iteration: 75062386, states[0] = 14.238337, states[40]= 0.003832
Saving checkpoint... 
Iteration: 83532110, states[0] = 25.013099, states[40]= 0.001719
Saving checkpoint... 
Iteration: 91810543, states[0] = -94.722970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100021196, states[0] = 27.709955, states[40]= 0.002352
Saving checkpoint... 
Iteration: 108177816, states[0] = -76.700371, states[40]= 0.000002
Saving checkpoint... 
Iteration: 116852090, states[0] = -94.771861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125494897, states[0] = -94.843696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133751289, states[0] = -94.597323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141954839, states[0] = -94.832309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150331460, states[0] = -94.748981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158509989, states[0] = 28.421555, states[40]= 0.049116
Saving checkpoint... 
Iteration: 166668930, states[0] = -65.269384, states[40]= 0.000010
Saving checkpoint... 
Iteration: 174967461, states[0] = -94.835865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183239278, states[0] = -94.560396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191905485, states[0] = -94.810157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200508252, states[0] = 28.623604, states[40]= 0.087615
Saving checkpoint... 
Iteration: 208940780, states[0] = -94.826544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217551277, states[0] = 18.534133, states[40]= 0.002943
Saving checkpoint... 
Iteration: 226147146, states[0] = -44.551388, states[40]= 0.000266
Saving checkpoint... 
Iteration: 234804741, states[0] = -94.711429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243277375, states[0] = -94.660798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251615751, states[0] = -18.800975, states[40]= 0.001558
Saving checkpoint... 
Iteration: 260035025, states[0] = 24.139762, states[40]= 0.001858
Saving checkpoint... 
Iteration: 268455964, states[0] = -94.831720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277157420, states[0] = -53.849627, states[40]= 0.000066
Saving checkpoint... 
Iteration: 285748409, states[0] = -94.587825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294202584, states[0] = -94.368798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302642297, states[0] = -40.373860, states[40]= 0.000466
Saving checkpoint... 
Iteration: 311258134, states[0] = -94.614729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319876408, states[0] = -94.790730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328187790, states[0] = -90.679280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336294135, states[0] = -94.693158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344685326, states[0] = -87.976469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353188217, states[0] = -91.045983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361837753, states[0] = -94.755037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370530433, states[0] = 25.533700, states[40]= 0.001677
Saving checkpoint... 
Iteration: 378981842, states[0] = -94.838828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387447573, states[0] = -94.828328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396302727, states[0] = -94.707530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404911010, states[0] = -94.812199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413306165, states[0] = -94.712938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421716779, states[0] = -94.478505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430161058, states[0] = -57.278494, states[40]= 0.000038
Saving checkpoint... 
Iteration: 438808263, states[0] = -94.716080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447414235, states[0] = -94.813701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455890747, states[0] = -94.800169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464335144, states[0] = -94.751681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473017218, states[0] = 28.252010, states[40]= 0.005299
Saving checkpoint... 
Iteration: 481746914, states[0] = -94.582640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490377211, states[0] = -94.790658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498914169, states[0] = -94.813465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507131788, states[0] = -31.742717, states[40]= 0.001211
Saving checkpoint... 
Iteration: 515560282, states[0] = 15.128859, states[40]= 0.003677
Saving checkpoint... 
Iteration: 524080414, states[0] = 6.221834, states[40]= 0.004875
Saving checkpoint... 
Iteration: 532723910, states[0] = -94.505761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541416251, states[0] = -94.814348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549756626, states[0] = -94.609776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558032841, states[0] = 24.820260, states[40]= 0.001760
Saving checkpoint... 
Iteration: 566495424, states[0] = -94.841310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575139317, states[0] = -37.878369, states[40]= 0.000637
Saving checkpoint... 
Iteration: 583592541, states[0] = -0.591704, states[40]= 0.004677
Saving checkpoint... 
Iteration: 591894418, states[0] = -94.801965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600316216, states[0] = -94.727095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608756592, states[0] = -94.609452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617439003, states[0] = -94.824181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625922568, states[0] = -94.817069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634145055, states[0] = -42.728129, states[40]= 0.000341
Saving checkpoint... 
Iteration: 642747325, states[0] = -94.583220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651292197, states[0] = -94.688428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659947104, states[0] = -94.827092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668693712, states[0] = -93.640931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677451563, states[0] = -94.828611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685803585, states[0] = -94.707776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694479398, states[0] = -94.836965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703292528, states[0] = -94.688825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711914720, states[0] = -94.812912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720390863, states[0] = -94.799209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728794598, states[0] = -94.692434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737222713, states[0] = -94.500475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745691840, states[0] = -93.109503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754258755, states[0] = -94.614607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762518854, states[0] = 28.075387, states[40]= 0.003587
Saving checkpoint... 
Iteration: 770680469, states[0] = -80.639364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 779096168, states[0] = -2.991393, states[40]= 0.004319
Saving checkpoint... 
Iteration: 787574380, states[0] = 9.134829, states[40]= 0.004640
Saving checkpoint... 
Iteration: 795648715, states[0] = -45.929770, states[40]= 0.000219
Saving checkpoint... 
Iteration: 803842219, states[0] = -94.758174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812011653, states[0] = 28.416137, states[40]= 0.028376
Saving checkpoint... 
Iteration: 820533881, states[0] = 24.500238, states[40]= 0.001805
Saving checkpoint... 
Iteration: 828974119, states[0] = -94.835024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837415695, states[0] = -94.812912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845459757, states[0] = -94.830690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853821964, states[0] = -94.733922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862209953, states[0] = -94.444521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870625895, states[0] = -27.022894, states[40]= 0.001579
Saving checkpoint... 
Iteration: 878960750, states[0] = -94.830875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887287733, states[0] = -94.679178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895722428, states[0] = -94.498772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903984208, states[0] = -94.837370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912515118, states[0] = 28.389106, states[40]= 0.009538
Saving checkpoint... 
Iteration: 921161007, states[0] = -57.226939, states[40]= 0.000038
Saving checkpoint... 
Iteration: 929958998, states[0] = -94.830116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938318682, states[0] = -94.729182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946242368, states[0] = -94.566989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954574627, states[0] = 9.020615, states[40]= 0.004653
Saving checkpoint... 
Iteration: 963271074, states[0] = -94.643984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971901804, states[0] = -94.804906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980610891, states[0] = -14.695400, states[40]= 0.001879
Saving checkpoint... 
Iteration: 988972480, states[0] = -94.833943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997369137, states[0] = -94.782428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005768327, states[0] = -94.637427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014445338, states[0] = -94.825056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022714625, states[0] = -94.466992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031030317, states[0] = 25.567787, states[40]= 0.001674
Saving checkpoint... 
Iteration: 1039369402, states[0] = -94.782477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047747180, states[0] = -94.581190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056101305, states[0] = -6.764839, states[40]= 0.003511
Saving checkpoint... 
Iteration: 1064238243, states[0] = -94.553426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072533043, states[0] = 24.759189, states[40]= 0.001769
Saving checkpoint... 
Iteration: 1080830397, states[0] = -94.743675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089273118, states[0] = -94.648118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097716203, states[0] = -94.473431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105917535, states[0] = -94.812776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114341242, states[0] = -94.755910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122819164, states[0] = -94.729114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131324220, states[0] = -94.735774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139695437, states[0] = -93.938854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147967969, states[0] = -94.832027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156342918, states[0] = -94.757533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164721975, states[0] = -94.495991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173354013, states[0] = -94.768548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182043786, states[0] = 21.207776, states[40]= 0.002381
Saving checkpoint... 
Iteration: 1190546341, states[0] = 20.310745, states[40]= 0.002563
Saving checkpoint... 
Iteration: 1199088782, states[0] = 1.694632, states[40]= 0.004875
Saving checkpoint... 
Iteration: 1207732765, states[0] = -94.534626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216191698, states[0] = -93.053972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224442368, states[0] = -94.823117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232701701, states[0] = -94.344912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241044469, states[0] = 20.969524, states[40]= 0.002428
Saving checkpoint... 
Iteration: 1249620504, states[0] = -22.698244, states[40]= 0.001589
Saving checkpoint... 
Iteration: 1258154329, states[0] = -50.990384, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1266387156, states[0] = -94.794634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274764860, states[0] = -94.628024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283308735, states[0] = -94.713481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291867123, states[0] = -94.779634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300235306, states[0] = -94.542836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308545974, states[0] = 20.440651, states[40]= 0.002536
Saving checkpoint... 
Iteration: 1316582140, states[0] = 5.341109, states[40]= 0.004912
Saving checkpoint... 
Iteration: 1324570113, states[0] = 11.055848, states[40]= 0.004397
Saving checkpoint... 
Iteration: 1333185357, states[0] = -88.001633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341636631, states[0] = -35.664894, states[40]= 0.000824
Saving checkpoint... 
Iteration: 1349913200, states[0] = -94.809640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358330967, states[0] = -94.743272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366716972, states[0] = -94.475542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374967967, states[0] = -94.831139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383826600, states[0] = -94.737811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392349412, states[0] = -94.763249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400680526, states[0] = -80.720651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409167939, states[0] = -64.169959, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1417841986, states[0] = -94.755517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426538966, states[0] = 22.854853, states[40]= 0.002071
Saving checkpoint... 
Iteration: 1435104720, states[0] = -9.498580, states[40]= 0.002861
Saving checkpoint... 
Iteration: 1443737203, states[0] = -94.548536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452452643, states[0] = -94.825956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461177232, states[0] = -75.662811, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1470111387, states[0] = -15.115619, states[40]= 0.001825
Saving checkpoint... 
Iteration: 1479033290, states[0] = 24.683893, states[40]= 0.001780
Saving checkpoint... 
Iteration: 1487602294, states[0] = -7.539461, states[40]= 0.003326
Saving checkpoint... 
Iteration: 1496177106, states[0] = -75.479009, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.714521
 - CaMKt in component CaMK (millimolar): 0.013216
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.735753
 - nass in component intracellular_ions (millimolar): 6.735848
 - ki in component intracellular_ions (millimolar): 145.144435
 - kss in component intracellular_ions (millimolar): 145.144415
 - cansr in component intracellular_ions (millimolar): 1.674277
 - cajsr in component intracellular_ions (millimolar): 1.630917
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003688
 - hf in component INa (dimensionless): 0.876712
 - hs in component INa (dimensionless): 0.876704
 - j in component INa (dimensionless): 0.876649
 - hsp in component INa (dimensionless): 0.719639
 - jp in component INa (dimensionless): 0.876611
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.697662
 - hLp in component INaL (dimensionless): 0.426879
 - a in component Ito (dimensionless): 0.000631
 - iF in component Ito (dimensionless): 0.999865
 - iS in component Ito (dimensionless): 0.594857
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999865
 - iSp in component Ito (dimensionless): 0.663169
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.906657
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999780
 - jca in component ICaL (dimensionless): 0.999964
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003095
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.387037
 - xs1 in component IKs (dimensionless): 0.285077
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997386
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:12:40 (2212): called boinc_finish(0)

</stderr_txt>
]]>


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