𝕏

Task 55546442

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_548_0
Workunit 26374274
Created 1 Jul 2024, 15:07:22 UTC
Sent 1 Jul 2024, 19:50:49 UTC
Report deadline 5 Jul 2024, 5:26:49 UTC
Received 4 Jul 2024, 22:58:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 59 min 3 sec
CPU time 2 hours 3 min 32 sec
Validate state Valid
Credit 65.11
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.36 MB
Peak swap size 5.43 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_548.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_548_0_r154564262_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_548_0_r154564262_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.632363
     * GNaL_b in INaL: 0.005664
     * Gto_b in Ito: 0.081690
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031414
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.164632
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.563190
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031976
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12084424, states[0] = -9.178894, states[40]= 0.002515
Saving checkpoint... 
Iteration: 26953456, states[0] = -95.089294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41822426, states[0] = -95.022276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56636949, states[0] = -57.652407, states[40]= 0.000008
Saving checkpoint... 
Iteration: 71517143, states[0] = 21.914383, states[40]= 0.013366
Saving checkpoint... 
Iteration: 85344816, states[0] = -95.009222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99639457, states[0] = -59.235968, states[40]= 0.000006
Saving checkpoint... 
Iteration: 114346809, states[0] = -95.004891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128461473, states[0] = -95.037532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142955140, states[0] = -95.035557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157463182, states[0] = -95.036331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171818317, states[0] = -94.985779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186545693, states[0] = 13.392276, states[40]= 0.005099
Saving checkpoint... 
Iteration: 200734765, states[0] = -94.901513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213973702, states[0] = -95.037049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225660617, states[0] = -89.375853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237273924, states[0] = -94.949387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248231541, states[0] = -94.896378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259824801, states[0] = -94.989080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273711896, states[0] = -94.863244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284641942, states[0] = -61.614962, states[40]= 0.000004
Saving checkpoint... 
Iteration: 297060799, states[0] = 7.336609, states[40]= 0.004853
Saving checkpoint... 
Iteration: 309178537, states[0] = -94.771474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322354150, states[0] = -95.004324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336046557, states[0] = 13.070838, states[40]= 0.005079
Saving checkpoint... 
Iteration: 348955509, states[0] = -95.033833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361125875, states[0] = -44.086879, states[40]= 0.000070
Saving checkpoint... 
Iteration: 374658698, states[0] = -86.625559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388330749, states[0] = -94.992415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402509846, states[0] = 23.574355, states[40]= 0.054400
Saving checkpoint... 
Iteration: 415693207, states[0] = -94.826327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429255097, states[0] = -94.928415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443950705, states[0] = -95.032910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456624608, states[0] = -42.792600, states[40]= 0.000086
Saving checkpoint... 
Iteration: 470667610, states[0] = -94.006478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482625607, states[0] = -43.811700, states[40]= 0.000073
Saving checkpoint... 
Iteration: 495587728, states[0] = -8.100770, states[40]= 0.002736
Saving checkpoint... 
Iteration: 507107797, states[0] = -26.538654, states[40]= 0.000636
Saving checkpoint... 
Iteration: 519249922, states[0] = -94.921920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531480312, states[0] = -95.037592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544301435, states[0] = -94.973074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556581521, states[0] = -3.484686, states[40]= 0.003695
Saving checkpoint... 
Iteration: 570974739, states[0] = -95.036773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582887674, states[0] = -95.017130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595535778, states[0] = 17.003615, states[40]= 0.005551
Saving checkpoint... 
Iteration: 608000851, states[0] = 45.767114, states[40]= 0.016723
Saving checkpoint... 
Iteration: 620865287, states[0] = -95.008905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635601337, states[0] = -20.450473, states[40]= 0.000941
Saving checkpoint... 
Iteration: 644900149, states[0] = -95.020967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656642067, states[0] = -61.759820, states[40]= 0.000004
Saving checkpoint... 
Iteration: 668974388, states[0] = -95.036661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681662923, states[0] = -91.748665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695690016, states[0] = -94.819141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710479744, states[0] = -95.037402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724099044, states[0] = -18.288225, states[40]= 0.001101
Saving checkpoint... 
Iteration: 737448094, states[0] = -95.032243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751664042, states[0] = -92.554317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766902982, states[0] = -95.021711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781461592, states[0] = -95.034596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795301725, states[0] = -94.973137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807553456, states[0] = 10.376839, states[40]= 0.004961
Saving checkpoint... 
Iteration: 821487064, states[0] = -95.038319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836186321, states[0] = -94.809910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850541386, states[0] = 15.009917, states[40]= 0.005238
Saving checkpoint... 
Iteration: 861643906, states[0] = -63.971479, states[40]= 0.000003
Saving checkpoint... 
Iteration: 875862626, states[0] = -95.007650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890035439, states[0] = 17.119412, states[40]= 0.005577
Saving checkpoint... 
Iteration: 901766117, states[0] = -94.940745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915453049, states[0] = -95.033041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929769201, states[0] = -94.944013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941410183, states[0] = -95.023589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951988010, states[0] = -95.038361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966134982, states[0] = -53.760055, states[40]= 0.000015
Saving checkpoint... 
Iteration: 979653902, states[0] = -78.400110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993569680, states[0] = 3.268302, states[40]= 0.004608
Saving checkpoint... 
Iteration: 1006186575, states[0] = -94.810495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018509108, states[0] = 23.878578, states[40]= 0.064600
Saving checkpoint... 
Iteration: 1029540350, states[0] = 15.388249, states[40]= 0.005282
Saving checkpoint... 
Iteration: 1042217924, states[0] = -94.873501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053985820, states[0] = -95.038012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065423297, states[0] = -95.026806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077873301, states[0] = -95.011757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088643041, states[0] = -62.920510, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1101974587, states[0] = -95.036421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115318059, states[0] = -94.984308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129507676, states[0] = 24.760148, states[40]= 0.089694
Saving checkpoint... 
Iteration: 1141885524, states[0] = -95.016067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153912625, states[0] = -95.024101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165073901, states[0] = 1.093664, states[40]= 0.004393
Saving checkpoint... 
Iteration: 1178297662, states[0] = -94.969770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189887041, states[0] = -95.016543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201306287, states[0] = -94.976247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212683833, states[0] = -94.801963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225020456, states[0] = 21.376730, states[40]= 0.009443
Saving checkpoint... 
Iteration: 1238203586, states[0] = -94.846873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251668996, states[0] = -94.275699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265881513, states[0] = -95.014617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279093362, states[0] = -12.993963, states[40]= 0.001774
Saving checkpoint... 
Iteration: 1292598084, states[0] = -17.383853, states[40]= 0.001186
Saving checkpoint... 
Iteration: 1302712723, states[0] = -94.864073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314557376, states[0] = 8.781370, states[40]= 0.004908
Saving checkpoint... 
Iteration: 1325628381, states[0] = -46.686671, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1336792594, states[0] = -94.965586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350378813, states[0] = -95.013611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364299064, states[0] = -94.970747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376345809, states[0] = -94.999735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388359285, states[0] = -95.005916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400826445, states[0] = -94.989293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410684082, states[0] = -94.802708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423960556, states[0] = -95.034024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436736695, states[0] = -94.903271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450907752, states[0] = -95.022616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464666489, states[0] = -93.691422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476036343, states[0] = 16.809525, states[40]= 0.005510
Saving checkpoint... 
Iteration: 1482523600, states[0] = 20.652055, states[40]= 0.007684
Saving checkpoint... 
Iteration: 1495827356, states[0] = -94.989770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508459249, states[0] = 3.513628, states[40]= 0.005140
Saving checkpoint... 
Iteration: 1521897185, states[0] = -95.278569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534858244, states[0] = 3.421448, states[40]= 0.005213
Saving checkpoint... 
Iteration: 1546054242, states[0] = -95.037112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557890072, states[0] = -95.297328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568878522, states[0] = -95.149505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580308919, states[0] = -95.212689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593024212, states[0] = 19.652629, states[40]= 0.008620
Saving checkpoint... 
Iteration: 1606611374, states[0] = -50.588880, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1617330737, states[0] = 17.035036, states[40]= 0.007037
Saving checkpoint... 
Iteration: 1627392923, states[0] = -95.187561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638490198, states[0] = -95.182373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649302573, states[0] = -95.206566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662872789, states[0] = -95.295101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676108244, states[0] = 25.290853, states[40]= 0.076312
Saving checkpoint... 
Iteration: 1689328766, states[0] = 17.842216, states[40]= 0.007371
Saving checkpoint... 
Iteration: 1700573055, states[0] = -95.144368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710996277, states[0] = -33.476319, states[40]= 0.000313
Saving checkpoint... 
Iteration: 1724470169, states[0] = -5.860557, states[40]= 0.003631
Saving checkpoint... 
Iteration: 1736913085, states[0] = -95.225014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750909693, states[0] = -48.721908, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1764274380, states[0] = -95.296698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775752568, states[0] = 6.207583, states[40]= 0.005493
Saving checkpoint... 
Iteration: 1786162592, states[0] = -95.286370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799466984, states[0] = -3.193807, states[40]= 0.004227
Saving checkpoint... 
Iteration: 1811647307, states[0] = -73.525839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1822237063, states[0] = -94.938354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833883472, states[0] = -95.039983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844184253, states[0] = -94.822832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857088951, states[0] = -9.737410, states[40]= 0.002398
Saving checkpoint... 
Iteration: 1869833632, states[0] = -95.001746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880510907, states[0] = 23.198681, states[40]= 0.042592
Saving checkpoint... 
Iteration: 1890561604, states[0] = 6.889492, states[40]= 0.004838
Saving checkpoint... 
Iteration: 1902301803, states[0] = -94.975795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914889142, states[0] = -95.019017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925039613, states[0] = 15.630299, states[40]= 0.005317
Saving checkpoint... 
Iteration: 1936315955, states[0] = -94.983604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948242958, states[0] = -94.912631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958465301, states[0] = -95.035047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972205462, states[0] = -94.850428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984797182, states[0] = -94.969130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995347328, states[0] = -95.000248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007442217, states[0] = -95.030416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017875267, states[0] = -95.011962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030268191, states[0] = -94.942285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042251454, states[0] = -94.922909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052165355, states[0] = -93.255484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064270505, states[0] = -94.944637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077901237, states[0] = -95.020358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087235575, states[0] = -94.901180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098842366, states[0] = -94.997527, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.914941
 - CaMKt in component CaMK (millimolar): 0.006938
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.533400
 - nass in component intracellular_ions (millimolar): 6.533459
 - ki in component intracellular_ions (millimolar): 145.444825
 - kss in component intracellular_ions (millimolar): 145.444806
 - cansr in component intracellular_ions (millimolar): 1.309687
 - cajsr in component intracellular_ions (millimolar): 1.271725
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003614
 - hf in component INa (dimensionless): 0.880228
 - hs in component INa (dimensionless): 0.880223
 - j in component INa (dimensionless): 0.880194
 - hsp in component INa (dimensionless): 0.726258
 - jp in component INa (dimensionless): 0.880175
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710169
 - hLp in component INaL (dimensionless): 0.452111
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620888
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695633
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934671
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001596
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332581
 - xs1 in component IKs (dimensionless): 0.242278
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:58:03 (15312): called boinc_finish(0)

</stderr_txt>
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