𝕏

Task 55546441

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_48_1
Workunit 26374273
Created 1 Jul 2024, 15:07:22 UTC
Sent 1 Jul 2024, 19:50:49 UTC
Report deadline 5 Jul 2024, 5:26:49 UTC
Received 4 Jul 2024, 20:10:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 32 min 38 sec
CPU time 2 hours 20 min 32 sec
Validate state Valid
Credit 61.73
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.33 MB
Peak swap size 5.43 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_48.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_48_1_r106368959_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_48_1_r106368959_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.142452
     * GNaL_b in INaL: 0.005656
     * Gto_b in Ito: 0.082276
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031487
     * GKs_b in IKs: 0.001943
     * GK1_b in IK1: 0.162995
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.195122
     * GKb_b in IKb: 0.003830
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030250
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12674589, states[0] = -94.886233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27731117, states[0] = -94.958385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42513142, states[0] = 22.396497, states[40]= 0.026242
Saving checkpoint... 
Iteration: 57517427, states[0] = 21.687894, states[40]= 0.012876
Saving checkpoint... 
Iteration: 69881750, states[0] = -95.037564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84066052, states[0] = 4.607146, states[40]= 0.004720
Saving checkpoint... 
Iteration: 99159940, states[0] = -89.462030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114189844, states[0] = -94.827750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129118730, states[0] = -37.524995, states[40]= 0.000184
Saving checkpoint... 
Iteration: 144134095, states[0] = -53.374129, states[40]= 0.000016
Saving checkpoint... 
Iteration: 159180635, states[0] = -94.793846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174149116, states[0] = -71.468912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189195168, states[0] = -94.835849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204200958, states[0] = -94.847639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218146820, states[0] = -68.218718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 233223069, states[0] = -94.888512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248161658, states[0] = -90.856765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263134381, states[0] = -53.565481, states[40]= 0.000015
Saving checkpoint... 
Iteration: 278085435, states[0] = -6.576153, states[40]= 0.003069
Saving checkpoint... 
Iteration: 292604479, states[0] = -23.784052, states[40]= 0.000764
Saving checkpoint... 
Iteration: 307576900, states[0] = -0.804946, states[40]= 0.004149
Saving checkpoint... 
Iteration: 322451566, states[0] = -95.040970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337372339, states[0] = -95.019338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352375934, states[0] = -95.020691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367355121, states[0] = -95.012096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382314386, states[0] = -94.989404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397235336, states[0] = -94.907823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412226758, states[0] = -94.894395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427267244, states[0] = -94.948717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439403002, states[0] = -95.029558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453917317, states[0] = -95.033433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468625075, states[0] = -43.694062, states[40]= 0.000074
Saving checkpoint... 
Iteration: 483249531, states[0] = -94.927613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498281707, states[0] = -94.963261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512834231, states[0] = -95.001489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527264590, states[0] = -94.945735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539953429, states[0] = -95.041167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554657604, states[0] = -85.355718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567475857, states[0] = -95.044824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581981434, states[0] = -95.045615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596947218, states[0] = -95.039971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612006110, states[0] = 26.476685, states[40]= 0.124100
Saving checkpoint... 
Iteration: 626909609, states[0] = -95.031298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641777881, states[0] = -94.959518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655895267, states[0] = -95.027098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670944656, states[0] = -95.039426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683503657, states[0] = 33.704563, states[40]= 0.148884
Saving checkpoint... 
Iteration: 698362957, states[0] = -95.015319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713191136, states[0] = -94.826310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728241377, states[0] = -94.916407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743302535, states[0] = -94.980692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758375891, states[0] = -95.020419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773503955, states[0] = 32.334775, states[40]= 0.151824
Saving checkpoint... 
Iteration: 788572826, states[0] = 1.474059, states[40]= 0.004440
Saving checkpoint... 
Iteration: 803604573, states[0] = -23.871198, states[40]= 0.000760
Saving checkpoint... 
Iteration: 818646184, states[0] = -67.357151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 833611618, states[0] = -30.534731, states[40]= 0.000443
Saving checkpoint... 
Iteration: 848437018, states[0] = -95.037757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863043913, states[0] = 13.934866, states[40]= 0.005151
Saving checkpoint... 
Iteration: 877815840, states[0] = -94.990067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892261934, states[0] = -94.942506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907085031, states[0] = -6.264503, states[40]= 0.003136
Saving checkpoint... 
Iteration: 921530315, states[0] = 18.658917, states[40]= 0.006114
Saving checkpoint... 
Iteration: 936520076, states[0] = 21.342034, states[40]= 0.009770
Saving checkpoint... 
Iteration: 951445029, states[0] = -95.039325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966209755, states[0] = -94.864088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980984603, states[0] = -95.045803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995824375, states[0] = -94.995439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010661710, states[0] = -90.900854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025509077, states[0] = 23.796335, states[40]= 0.065376
Saving checkpoint... 
Iteration: 1037986097, states[0] = -95.045968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052876321, states[0] = -95.020395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067668372, states[0] = -94.209995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082105775, states[0] = -25.005041, states[40]= 0.000707
Saving checkpoint... 
Iteration: 1096969734, states[0] = -95.043567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111604659, states[0] = -23.952148, states[40]= 0.000756
Saving checkpoint... 
Iteration: 1126473704, states[0] = -95.044156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141373837, states[0] = -95.019405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156336696, states[0] = -95.002441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169891183, states[0] = -95.025482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184873851, states[0] = -95.019384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199849309, states[0] = -95.008857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214834879, states[0] = -95.001410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229803457, states[0] = -94.981084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244264720, states[0] = -94.945432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258893513, states[0] = -95.026172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272410096, states[0] = -95.031028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285723279, states[0] = -94.888083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300347344, states[0] = -95.007842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314706270, states[0] = -94.857184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329440761, states[0] = -95.038235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341932246, states[0] = -95.036418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356514760, states[0] = 22.346407, states[40]= 0.019477
Saving checkpoint... 
Iteration: 1371496403, states[0] = -95.047073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386604993, states[0] = -24.267064, states[40]= 0.000741
Saving checkpoint... 
Iteration: 1401639946, states[0] = -59.767454, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1415838269, states[0] = -95.003126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430647807, states[0] = -69.540773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445677367, states[0] = -94.762731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460704547, states[0] = -94.853721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475126505, states[0] = -45.167078, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1489226438, states[0] = -94.893197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501281150, states[0] = -13.477499, states[40]= 0.001836
Saving checkpoint... 
Iteration: 1516051235, states[0] = -94.875356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531000587, states[0] = -37.073292, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1545877155, states[0] = -95.293038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560571774, states[0] = -95.295012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575427371, states[0] = -72.105561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1590251666, states[0] = -95.282428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605107443, states[0] = -46.375315, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1619833814, states[0] = -84.082032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634521838, states[0] = -64.450876, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1649018379, states[0] = -95.243113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661933281, states[0] = -95.264435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676291640, states[0] = -95.195624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690960790, states[0] = -95.118256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705542215, states[0] = 11.518223, states[40]= 0.005981
Saving checkpoint... 
Iteration: 1720286908, states[0] = -23.685635, states[40]= 0.000786
Saving checkpoint... 
Iteration: 1735065601, states[0] = -95.133892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749835504, states[0] = -95.267605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763500095, states[0] = -38.116547, states[40]= 0.000171
Saving checkpoint... 
Iteration: 1778229195, states[0] = -75.818174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792953496, states[0] = -95.065854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807741260, states[0] = -94.964014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822510780, states[0] = 22.943752, states[40]= 0.043871
Saving checkpoint... 
Iteration: 1837190411, states[0] = -94.847537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851842203, states[0] = -95.020103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866522494, states[0] = 20.703574, states[40]= 0.008156
Saving checkpoint... 
Iteration: 1880831782, states[0] = -95.005676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894508425, states[0] = 24.119877, states[40]= 0.076080
Saving checkpoint... 
Iteration: 1907418420, states[0] = -95.035696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922182076, states[0] = -94.801123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936985980, states[0] = -95.046574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951762693, states[0] = -94.943469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966480339, states[0] = -95.045066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980177984, states[0] = -94.770264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994367070, states[0] = -95.016390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008948051, states[0] = -95.039347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023060295, states[0] = 7.394353, states[40]= 0.004859
Saving checkpoint... 
Iteration: 2037382370, states[0] = -95.021980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051909568, states[0] = -95.030388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066428679, states[0] = -95.035140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080988697, states[0] = -95.045627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095178226, states[0] = -94.772207, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.922881
 - CaMKt in component CaMK (millimolar): 0.006936
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.538370
 - nass in component intracellular_ions (millimolar): 6.538430
 - ki in component intracellular_ions (millimolar): 145.439736
 - kss in component intracellular_ions (millimolar): 145.439717
 - cansr in component intracellular_ions (millimolar): 1.310190
 - cajsr in component intracellular_ions (millimolar): 1.272270
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003611
 - hf in component INa (dimensionless): 0.880365
 - hs in component INa (dimensionless): 0.880361
 - j in component INa (dimensionless): 0.880331
 - hsp in component INa (dimensionless): 0.726517
 - jp in component INa (dimensionless): 0.880312
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710436
 - hLp in component INaL (dimensionless): 0.452519
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621344
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696217
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935193
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001598
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332150
 - xs1 in component IKs (dimensionless): 0.241304
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:10:04 (3720): called boinc_finish(0)

</stderr_txt>
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