𝕏

Task 55540597

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_2000-conf_543_1
Workunit 26371354
Created 1 Jul 2024, 15:04:40 UTC
Sent 1 Jul 2024, 19:18:47 UTC
Report deadline 4 Jul 2024, 19:18:47 UTC
Received 2 Jul 2024, 18:34:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235817
Run time 1 hours 39 min 20 sec
CPU time 1 hours 25 min 13 sec
Validate state Valid
Credit 44.30
Device peak FLOPS 4.10 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.11 MB
Peak swap size 1.78 MB
Peak disk usage 0.63 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_2000-conf_543.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_2000-conf_543_1_r1677644756_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_2000-conf_543_1_r1677644756_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.114295
     * GNaL_b in INaL: 0.005550
     * Gto_b in Ito: 0.083574
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031660
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.160828
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.370883
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036775
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8977456, states[0] = -94.800514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19901685, states[0] = -94.734016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30909172, states[0] = -94.699944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41265879, states[0] = -94.421834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51484797, states[0] = -94.644578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61822672, states[0] = -94.666043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72227675, states[0] = -94.273806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81064524, states[0] = 14.263645, states[40]= 0.003719
Saving checkpoint... 
Iteration: 90194651, states[0] = -93.537816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98163199, states[0] = -59.569144, states[40]= 0.000020
Saving checkpoint... 
Iteration: 108602457, states[0] = -94.645733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118920467, states[0] = -94.648638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126900198, states[0] = -94.648303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136098817, states[0] = -2.781219, states[40]= 0.004052
Saving checkpoint... 
Iteration: 146146716, states[0] = -43.618849, states[40]= 0.000242
Saving checkpoint... 
Iteration: 157163352, states[0] = -59.297835, states[40]= 0.000021
Saving checkpoint... 
Iteration: 168720658, states[0] = -94.647402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179564922, states[0] = -94.636465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189488945, states[0] = -94.619640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196314998, states[0] = -94.484011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204834074, states[0] = -94.646501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215266484, states[0] = -94.382470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226110926, states[0] = -12.331751, states[40]= 0.002085
Saving checkpoint... 
Iteration: 236225224, states[0] = -94.249578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247155310, states[0] = -51.485837, states[40]= 0.000075
Saving checkpoint... 
Iteration: 257844338, states[0] = -94.645933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267559175, states[0] = -94.634697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278100346, states[0] = -3.768763, states[40]= 0.003881
Saving checkpoint... 
Iteration: 288793381, states[0] = -94.646410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297386086, states[0] = -94.565774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307869544, states[0] = -94.645324, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_2000-conf_543.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_2000-conf_543_1_r1677644756_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_2000-conf_543_1_r1677644756_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.114295
     * GNaL_b in INaL: 0.005550
     * Gto_b in Ito: 0.083574
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031660
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.160828
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.370883
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036775
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 307869544
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.645324 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 313808958, states[0] = -94.646214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323286834, states[0] = -94.430603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331480228, states[0] = -94.615980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340197974, states[0] = -93.855895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345956225, states[0] = -94.643253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355027507, states[0] = 25.657739, states[40]= 0.001813
Saving checkpoint... 
Iteration: 364306249, states[0] = -94.468407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373880235, states[0] = -94.644971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382472110, states[0] = -94.613066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392790084, states[0] = -94.646201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402988437, states[0] = -94.642297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413684700, states[0] = -94.644988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423193292, states[0] = -93.046825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432455915, states[0] = -94.606686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442145221, states[0] = -42.137140, states[40]= 0.000298
Saving checkpoint... 
Iteration: 449937316, states[0] = -94.643533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461019044, states[0] = 26.836018, states[40]= 0.003669
Saving checkpoint... 
Iteration: 468588292, states[0] = -94.638193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479449968, states[0] = -94.604043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487905700, states[0] = -94.644214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497313182, states[0] = -94.479977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506936914, states[0] = -94.643440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517587873, states[0] = -94.638056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528547079, states[0] = -94.632139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538477622, states[0] = -94.614714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549091551, states[0] = 1.883799, states[40]= 0.004559
Saving checkpoint... 
Iteration: 557446308, states[0] = -94.602257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567990204, states[0] = -94.641951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578471589, states[0] = -94.612521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589435610, states[0] = -94.597055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600527864, states[0] = -94.628284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610816096, states[0] = -94.645582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621443287, states[0] = -94.600740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631959240, states[0] = -94.642652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642389549, states[0] = -94.567858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653066391, states[0] = 13.731838, states[40]= 0.003858
Saving checkpoint... 
Iteration: 663817388, states[0] = -94.645472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674470484, states[0] = -94.611947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684510097, states[0] = -94.624017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693748334, states[0] = -94.645669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703925869, states[0] = -94.643355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715264297, states[0] = -94.375391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726277004, states[0] = -94.407609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737349315, states[0] = -94.529432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748189037, states[0] = -90.844265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759116111, states[0] = -16.903904, states[40]= 0.001486
Saving checkpoint... 
Iteration: 769720696, states[0] = -94.645231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780336833, states[0] = -94.514104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791005903, states[0] = 28.324798, states[40]= 0.187689
Saving checkpoint... 
Iteration: 800694565, states[0] = -94.644598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810964550, states[0] = -94.642192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821811076, states[0] = -94.645257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832053430, states[0] = 18.408520, states[40]= 0.003002
Saving checkpoint... 
Iteration: 841883918, states[0] = -94.644050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852200244, states[0] = -94.001734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861637535, states[0] = -94.641879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871932117, states[0] = -94.642902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881991638, states[0] = -94.641348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892197088, states[0] = -93.767891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902340098, states[0] = -94.518056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912521159, states[0] = -94.626252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923091711, states[0] = 1.791559, states[40]= 0.004555
Saving checkpoint... 
Iteration: 933651859, states[0] = -94.642613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944704576, states[0] = -94.644598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954990397, states[0] = -94.641251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965046258, states[0] = 20.712562, states[40]= 0.002539
Saving checkpoint... 
Iteration: 975471876, states[0] = -94.611911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985149766, states[0] = -46.290875, states[40]= 0.000165
Saving checkpoint... 
Iteration: 995577202, states[0] = -94.635884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006044525, states[0] = 21.242904, states[40]= 0.002436
Saving checkpoint... 
Iteration: 1015277862, states[0] = -94.409115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026226659, states[0] = -94.253348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036461597, states[0] = -94.607912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046362614, states[0] = -94.543196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054675536, states[0] = -94.643502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065409495, states[0] = -94.581254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075968130, states[0] = -94.641623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086851431, states[0] = -94.644224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097608836, states[0] = -94.639196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108506846, states[0] = -94.622424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118623534, states[0] = -94.640410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129386550, states[0] = -94.564610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140211597, states[0] = -94.189796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150520154, states[0] = -94.625595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161044251, states[0] = 21.325868, states[40]= 0.002420
Saving checkpoint... 
Iteration: 1171253511, states[0] = -94.343821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181292909, states[0] = -94.441699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191955746, states[0] = -94.641735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202940616, states[0] = -94.642097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213335603, states[0] = -94.511714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224471439, states[0] = -94.611305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235231203, states[0] = -94.269705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250201027, states[0] = -94.034326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265456128, states[0] = -94.605275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276438233, states[0] = -94.597127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287583408, states[0] = -94.636141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298011294, states[0] = 26.835017, states[40]= 0.031812
Saving checkpoint... 
Iteration: 1309077189, states[0] = 9.191738, states[40]= 0.004406
Saving checkpoint... 
Iteration: 1320623376, states[0] = -94.640035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331358791, states[0] = -94.538753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342416384, states[0] = -94.585058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353770508, states[0] = -94.644538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364459912, states[0] = -94.606649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375351048, states[0] = -94.530253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385453058, states[0] = -94.603759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395482141, states[0] = -94.614684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405615070, states[0] = -94.639199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415833579, states[0] = -94.643911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425452160, states[0] = -94.603300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435971858, states[0] = -94.640878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445778658, states[0] = -94.644357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456843465, states[0] = -94.643689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467280396, states[0] = -94.414191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478511383, states[0] = -94.622912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489388899, states[0] = -94.565823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499661761, states[0] = -94.642104, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.515950
 - CaMKt in component CaMK (millimolar): 0.004194
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.477303
 - nass in component intracellular_ions (millimolar): 6.477389
 - ki in component intracellular_ions (millimolar): 145.435375
 - kss in component intracellular_ions (millimolar): 145.435360
 - cansr in component intracellular_ions (millimolar): 1.589564
 - cajsr in component intracellular_ions (millimolar): 1.588851
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003762
 - hf in component INa (dimensionless): 0.873141
 - hs in component INa (dimensionless): 0.873142
 - j in component INa (dimensionless): 0.873148
 - hsp in component INa (dimensionless): 0.713065
 - jp in component INa (dimensionless): 0.873151
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.718729
 - hLp in component INaL (dimensionless): 0.510634
 - a in component Ito (dimensionless): 0.000640
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.892070
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.931827
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975744
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002712
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097889
 - xs1 in component IKs (dimensionless): 0.124362
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997437
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:33:44 (15112): called boinc_finish(0)

</stderr_txt>
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