𝕏

Task 55536846

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_139_1
Workunit 26369479
Created 1 Jul 2024, 15:02:51 UTC
Sent 1 Jul 2024, 19:01:57 UTC
Report deadline 4 Jul 2024, 19:01:57 UTC
Received 2 Jul 2024, 9:12:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240982
Run time 1 hours 38 min 29 sec
CPU time 1 hours 36 min 42 sec
Validate state Valid
Credit 47.86
Device peak FLOPS 3.10 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 1.24 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_139.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_139_1_r1991264224_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_139_1_r1991264224_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.593024
     * GNaL_b in INaL: 0.005617
     * Gto_b in Ito: 0.081423
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031357
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.162336
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.371606
     * GKb_b in IKb: 0.003815
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036207
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6773045, states[0] = -86.778959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16569198, states[0] = -86.689989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26259666, states[0] = -86.480175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35978327, states[0] = -86.588776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45587781, states[0] = -86.562731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55362239, states[0] = -86.543576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65136976, states[0] = -86.530821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74920762, states[0] = -86.522295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84656570, states[0] = -86.512966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94425037, states[0] = -86.473377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104080860, states[0] = 5.980659, states[40]= 0.004128
Saving checkpoint... 
Iteration: 113876531, states[0] = -86.482038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123625451, states[0] = -86.480713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133388838, states[0] = -86.480878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143083596, states[0] = -86.483994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152771615, states[0] = -86.487139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162549629, states[0] = -86.477649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172161274, states[0] = -52.316607, states[40]= 0.000017
Saving checkpoint... 
Iteration: 181900408, states[0] = -86.468387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191566908, states[0] = -86.470761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201299013, states[0] = -86.473939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211015375, states[0] = -86.478787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220743784, states[0] = -86.482013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230447889, states[0] = -86.455331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240123804, states[0] = -20.102644, states[40]= 0.000906
Saving checkpoint... 
Iteration: 249883382, states[0] = -86.465903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259630769, states[0] = -86.467994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269289290, states[0] = -86.472467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278788265, states[0] = -86.480989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288376251, states[0] = -86.426515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298052746, states[0] = 15.345961, states[40]= 0.004261
Saving checkpoint... 
Iteration: 307818131, states[0] = -86.465917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317431622, states[0] = -86.470021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327134910, states[0] = -86.474934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336741645, states[0] = -86.480819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346342381, states[0] = -86.405040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355998079, states[0] = -86.464524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365715733, states[0] = -86.466673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375340403, states[0] = -86.471260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384940474, states[0] = -86.478626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394656048, states[0] = -86.479420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404361581, states[0] = -86.417862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414114391, states[0] = -12.306402, states[40]= 0.001619
Saving checkpoint... 
Iteration: 423756633, states[0] = -86.466263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433384102, states[0] = -86.470562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443055598, states[0] = -86.476370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452788214, states[0] = -86.480651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462504638, states[0] = -86.466596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472233931, states[0] = -86.275471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481928503, states[0] = -86.464909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491630878, states[0] = -86.467451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501306517, states[0] = -86.471747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510946034, states[0] = -86.478478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520670856, states[0] = -86.479792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530466179, states[0] = -86.458977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540177997, states[0] = -69.375073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 549873555, states[0] = -86.465287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559546614, states[0] = -86.468376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569262496, states[0] = -86.472468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579023368, states[0] = -86.476976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588847432, states[0] = -86.480054, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_139.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_139_1_r1991264224_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_139_1_r1991264224_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.593024
     * GNaL_b in INaL: 0.005617
     * Gto_b in Ito: 0.081423
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031357
     * GKs_b in IKs: 0.001973
     * GK1_b in IK1: 0.162336
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.371606
     * GKb_b in IKb: 0.003815
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036207
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 588847432
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.480054 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 598004695, states[0] = 25.835581, states[40]= 0.150347
Saving checkpoint... 
Iteration: 606861855, states[0] = -86.479857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615152693, states[0] = -86.474444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625883180, states[0] = -86.465202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636671518, states[0] = -86.479787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647668820, states[0] = -86.467033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658299033, states[0] = -86.365851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669009060, states[0] = -86.477241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679873839, states[0] = -86.465261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689862363, states[0] = -86.465345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700848337, states[0] = -86.480022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711770824, states[0] = -86.466078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722925426, states[0] = -86.478811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733717582, states[0] = -86.466549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744874874, states[0] = -86.479642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755856761, states[0] = -86.465376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766770972, states[0] = -86.480664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777375749, states[0] = -86.470616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788125405, states[0] = -21.393789, states[40]= 0.000860
Saving checkpoint... 
Iteration: 798822053, states[0] = -86.480310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809360647, states[0] = -86.470838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819541202, states[0] = -86.468393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829679605, states[0] = -86.466894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839872587, states[0] = -86.465241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850103511, states[0] = -4.472535, states[40]= 0.003014
Saving checkpoint... 
Iteration: 860252471, states[0] = -86.304251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870510116, states[0] = -86.467397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880621831, states[0] = -86.477957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890812681, states[0] = -86.480385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901127353, states[0] = -86.474876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911497220, states[0] = -86.468917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921853627, states[0] = -86.465369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932301644, states[0] = -86.368618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942622765, states[0] = -86.477991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953048806, states[0] = -86.476406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963152465, states[0] = -86.474385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973296947, states[0] = -86.471817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983454106, states[0] = -86.469467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993562965, states[0] = -86.468106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003706371, states[0] = -86.466605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013826896, states[0] = -86.465561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023870581, states[0] = -86.465223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033927057, states[0] = -86.464817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044100105, states[0] = -2.449389, states[40]= 0.003340
Saving checkpoint... 
Iteration: 1054337609, states[0] = -86.401276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064535189, states[0] = -86.470848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074608056, states[0] = -86.477190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084584165, states[0] = -86.475613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094619856, states[0] = -86.477820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104659918, states[0] = -86.479389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114668988, states[0] = -86.479637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124730101, states[0] = -86.480547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135043438, states[0] = -86.476479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145324736, states[0] = -86.471336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155099241, states[0] = -86.475376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165086082, states[0] = -86.475632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175041964, states[0] = -86.476501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185053123, states[0] = -86.476279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195080204, states[0] = -86.475742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204996730, states[0] = -86.477386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214825344, states[0] = -86.480201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223553472, states[0] = -86.468175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233560201, states[0] = -86.468095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243582404, states[0] = -86.467839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253882494, states[0] = -86.465093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263811819, states[0] = -86.465636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273783538, states[0] = -86.465868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283858388, states[0] = -86.465268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293888427, states[0] = -86.465043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303991210, states[0] = -86.464345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314134645, states[0] = -29.062283, states[40]= 0.000544
Saving checkpoint... 
Iteration: 1324234197, states[0] = -86.275725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334472569, states[0] = -86.460288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344474443, states[0] = -86.460698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354526138, states[0] = -86.469633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364562872, states[0] = -86.473775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374680868, states[0] = -86.479866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384871659, states[0] = -86.479575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394935856, states[0] = -86.478503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404970661, states[0] = -86.477853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415038039, states[0] = -86.476535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425177648, states[0] = -86.473829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435256292, states[0] = -86.472418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445461678, states[0] = -86.469283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452684859, states[0] = -86.479933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463079618, states[0] = -86.475705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473359920, states[0] = -86.470729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483552849, states[0] = -86.468136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493873295, states[0] = -86.465118, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.340224
 - CaMKt in component CaMK (millimolar): 0.000880
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.056952
 - nass in component intracellular_ions (millimolar): 6.056996
 - ki in component intracellular_ions (millimolar): 145.940351
 - kss in component intracellular_ions (millimolar): 145.940341
 - cansr in component intracellular_ions (millimolar): 1.243789
 - cajsr in component intracellular_ions (millimolar): 1.243934
 - cai in component intracellular_ions (millimolar): 0.000070
 - m in component INa (dimensionless): 0.008571
 - hf in component INa (dimensionless): 0.642366
 - hs in component INa (dimensionless): 0.642367
 - j in component INa (dimensionless): 0.642370
 - hsp in component INa (dimensionless): 0.393392
 - jp in component INa (dimensionless): 0.642371
 - mL in component INaL (dimensionless): 0.000252
 - hL in component INaL (dimensionless): 0.461846
 - hLp in component INaL (dimensionless): 0.272459
 - a in component Ito (dimensionless): 0.001110
 - iF in component Ito (dimensionless): 0.999417
 - iS in component Ito (dimensionless): 0.985456
 - ap in component Ito (dimensionless): 0.000566
 - iFp in component Ito (dimensionless): 0.999417
 - iSp in component Ito (dimensionless): 0.991570
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997478
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001242
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020793
 - xs1 in component IKs (dimensionless): 0.037323
 - xs2 in component IKs (dimensionless): 0.000229
 - xk1 in component IK1 (dimensionless): 0.997140
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:45:27 (12148): called boinc_finish(0)

</stderr_txt>
]]>


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