𝕏

Task 55532261

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_235_1
Workunit 26367190
Created 1 Jul 2024, 15:00:42 UTC
Sent 1 Jul 2024, 18:33:55 UTC
Report deadline 4 Jul 2024, 18:33:55 UTC
Received 3 Jul 2024, 10:16:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 219752
Run time 1 hours 50 min 55 sec
CPU time 40 min 48 sec
Validate state Valid
Credit 48.09
Device peak FLOPS 9.03 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.05 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_235.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_235_1_r1340823536_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_235_1_r1340823536_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.464748
     * GNaL_b in INaL: 0.006230
     * Gto_b in Ito: 0.084364
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031653
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.167381
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.622832
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035318
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 3810786, states[0] = -94.220971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 7392524, states[0] = -94.163494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 10805256, states[0] = -94.119186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15632817, states[0] = -94.088869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20417973, states[0] = -94.039108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24555379, states[0] = -94.028615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28595883, states[0] = -94.014726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32073863, states[0] = -93.998237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35581524, states[0] = -93.986266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40482597, states[0] = -93.993439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45083936, states[0] = 12.569201, states[40]= 0.002224
Saving checkpoint... 
Iteration: 49283030, states[0] = -93.990697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53322406, states[0] = -93.969637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57521473, states[0] = -93.969709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61171151, states[0] = -93.988889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64709860, states[0] = -93.973805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68988146, states[0] = -93.959641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73392272, states[0] = -93.979437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76937848, states[0] = -93.967802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80391444, states[0] = -93.962114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85197604, states[0] = -93.984096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90010640, states[0] = 30.934797, states[40]= 0.047156
Saving checkpoint... 
Iteration: 93941213, states[0] = -93.992440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98062145, states[0] = -93.964425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102806317, states[0] = -93.995140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107631094, states[0] = -93.958492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111818537, states[0] = -93.994705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116000974, states[0] = -93.964603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119521554, states[0] = -93.958993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123119942, states[0] = -6.449427, states[40]= 0.003331
Saving checkpoint... 
Iteration: 127969390, states[0] = -93.964785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132799537, states[0] = -93.994439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137520146, states[0] = -93.958675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141732781, states[0] = -93.993864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145750289, states[0] = -93.968066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149386779, states[0] = -93.959680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153040998, states[0] = 27.914603, states[40]= 0.000237
Saving checkpoint... 
Iteration: 157819104, states[0] = -93.966738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162497046, states[0] = -93.952289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167286260, states[0] = -93.960499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171465357, states[0] = -93.934927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175720356, states[0] = -93.968374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179366171, states[0] = -93.959641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182847144, states[0] = -93.956010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186433483, states[0] = -93.911355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191164925, states[0] = -93.961683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195960159, states[0] = -93.990130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200244602, states[0] = -93.960762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204386482, states[0] = -93.860685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207797846, states[0] = -93.993889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211421932, states[0] = -93.974964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214913427, states[0] = -93.964934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219778112, states[0] = -93.993906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224577552, states[0] = -93.957675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228716975, states[0] = -93.992925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232855815, states[0] = -93.965788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236359724, states[0] = -93.959499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239864682, states[0] = -93.955713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243481079, states[0] = -93.943891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248194612, states[0] = -93.961173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252932592, states[0] = -93.990863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256995996, states[0] = -93.963633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261240290, states[0] = -93.426558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264817668, states[0] = -93.993562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268423582, states[0] = -93.974783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271959721, states[0] = -93.964116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276684589, states[0] = -93.991360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281364510, states[0] = -93.959361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285620382, states[0] = -93.985390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289896607, states[0] = -93.965026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293477529, states[0] = -93.958333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297051777, states[0] = 24.598435, states[40]= 0.000432
Saving checkpoint... 
Iteration: 300454736, states[0] = -93.927495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305209141, states[0] = -93.960905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309987264, states[0] = -93.988943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314183306, states[0] = -93.961179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318360926, states[0] = -93.821630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321898827, states[0] = -93.991745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325410687, states[0] = -93.975031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328995621, states[0] = -93.963510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333759528, states[0] = -93.993591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338563615, states[0] = -93.957563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342778303, states[0] = -93.993668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346819207, states[0] = -93.966182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350490000, states[0] = -93.958134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354048377, states[0] = 25.696214, states[40]= 0.000357
Saving checkpoint... 
Iteration: 357684113, states[0] = -93.991197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362458843, states[0] = -93.958378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367181439, states[0] = -93.981995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371390125, states[0] = -93.958974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375598001, states[0] = -93.981839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379205629, states[0] = -93.981160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382841859, states[0] = -93.965747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386422351, states[0] = -93.958659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391201981, states[0] = -93.981263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396043063, states[0] = 27.321967, states[40]= 0.000265
Saving checkpoint... 
Iteration: 400207386, states[0] = -93.981068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404547868, states[0] = -93.957581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408092597, states[0] = 8.952109, states[40]= 0.002890
Saving checkpoint... 
Iteration: 411732029, states[0] = -93.993028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415235462, states[0] = -93.980118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419920479, states[0] = -93.955085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424788145, states[0] = -93.966592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428943831, states[0] = -93.954942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433123972, states[0] = -93.983886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436698362, states[0] = -93.968227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440152029, states[0] = -93.961339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443765207, states[0] = -93.955976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448654314, states[0] = -93.969084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453474870, states[0] = -93.940055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457677822, states[0] = -93.968597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461793707, states[0] = -93.955767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465293643, states[0] = -93.657112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468952842, states[0] = -93.989855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472391194, states[0] = -93.975333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477144807, states[0] = -25.363691, states[40]= 0.002732
Saving checkpoint... 
Iteration: 481809764, states[0] = -93.966130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485868066, states[0] = -93.955281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490145365, states[0] = -93.983046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493734667, states[0] = -93.967448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497306781, states[0] = -93.959574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500820985, states[0] = -93.955538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505474308, states[0] = -93.973084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510357878, states[0] = -93.816014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514569440, states[0] = -93.970802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518733893, states[0] = -93.956062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522256787, states[0] = -93.511559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525853209, states[0] = -93.992547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529327109, states[0] = -93.977084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534209277, states[0] = -79.065300, states[40]= 0.000002
Saving checkpoint... 
Iteration: 539027482, states[0] = -93.962745, states[40]= 0.000000
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Iteration: 543266563, states[0] = -93.554360, states[40]= 0.000000
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Iteration: 547395655, states[0] = -93.975092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551538902, states[0] = -93.957422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555190539, states[0] = -59.831798, states[40]= 0.000055
Saving checkpoint... 
Iteration: 558826108, states[0] = -93.992977, states[40]= 0.000000
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Iteration: 563556680, states[0] = -93.957263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568208393, states[0] = -93.980772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573058029, states[0] = 22.487880, states[40]= 0.000611
Saving checkpoint... 
Iteration: 577153986, states[0] = -93.982611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581540364, states[0] = -93.957363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585228112, states[0] = -93.105876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588690350, states[0] = -93.991186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593411831, states[0] = -93.958429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598131060, states[0] = -93.983379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603016307, states[0] = 31.849055, states[40]= 0.006638
Saving checkpoint... 
Iteration: 607257653, states[0] = -93.979103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611426616, states[0] = -93.958269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615022443, states[0] = 31.715322, states[40]= 0.000868
Saving checkpoint... 
Iteration: 618438716, states[0] = -93.914917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623347899, states[0] = -93.958975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628286948, states[0] = -93.978149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633011239, states[0] = 31.088196, states[40]= 0.038304
Saving checkpoint... 
Iteration: 637154492, states[0] = -93.982500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641336844, states[0] = -93.959054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644855526, states[0] = -93.955106, states[40]= 0.000000
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Iteration: 648493475, states[0] = -93.949603, states[40]= 0.000000
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Iteration: 652193361, states[0] = -93.981145, states[40]= 0.000000
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Iteration: 656929257, states[0] = -93.954666, states[40]= 0.000000
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Iteration: 661725637, states[0] = -93.967355, states[40]= 0.000000
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Iteration: 665827071, states[0] = -93.955243, states[40]= 0.000000
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Iteration: 670079892, states[0] = -93.985085, states[40]= 0.000000
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Iteration: 673765256, states[0] = -93.966609, states[40]= 0.000000
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Iteration: 677354020, states[0] = -93.958832, states[40]= 0.000000
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Iteration: 680973413, states[0] = -93.954389, states[40]= 0.000000
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Iteration: 685757254, states[0] = -93.966734, states[40]= 0.000000
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Iteration: 690553903, states[0] = -93.971751, states[40]= 0.000000
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Iteration: 694765174, states[0] = -93.966577, states[40]= 0.000000
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Iteration: 699044316, states[0] = 26.950049, states[40]= 0.000284
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Iteration: 702587079, states[0] = -93.979343, states[40]= 0.000000
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Iteration: 706130509, states[0] = -93.983230, states[40]= 0.000000
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Iteration: 709735908, states[0] = -93.967088, states[40]= 0.000000
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Iteration: 714514874, states[0] = -93.958877, states[40]= 0.000000
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Iteration: 719367239, states[0] = -93.958642, states[40]= 0.000000
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Iteration: 723553904, states[0] = -93.971700, states[40]= 0.000000
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Iteration: 727633864, states[0] = -93.969071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731207434, states[0] = -93.960253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734718483, states[0] = -93.955826, states[40]= 0.000000
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Iteration: 738414547, states[0] = -93.892667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743306244, states[0] = -93.959195, states[40]= 0.000000
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Iteration: 747978631, states[0] = -93.988553, states[40]= 0.000000
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Iteration: 752111694, states[0] = -93.961334, states[40]= 0.000000
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Iteration: 756296882, states[0] = -93.667310, states[40]= 0.000000
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Iteration: 759859340, states[0] = -93.992052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763489299, states[0] = -93.972307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766941161, states[0] = -93.963601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771558906, states[0] = -93.972942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776344574, states[0] = -93.958768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780577367, states[0] = -93.977254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784737758, states[0] = -93.966937, states[40]= 0.000000
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Iteration: 788297279, states[0] = -93.959215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791915066, states[0] = -93.954534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795377251, states[0] = -93.846766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800091877, states[0] = -93.961504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804980138, states[0] = -93.988412, states[40]= 0.000000
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Iteration: 809201365, states[0] = -93.960199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813383004, states[0] = -93.854923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817629899, states[0] = -93.969013, states[40]= 0.000000
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Iteration: 821278973, states[0] = -93.959350, states[40]= 0.000000
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Iteration: 824883308, states[0] = -93.954662, states[40]= 0.000000
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Iteration: 829147619, states[0] = -93.982439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833882837, states[0] = -93.954651, states[40]= 0.000000
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Iteration: 837969236, states[0] = -93.988733, states[40]= 0.000000
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Iteration: 842106276, states[0] = -93.961260, states[40]= 0.000000
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Iteration: 846207456, states[0] = -76.656799, states[40]= 0.000003
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Iteration: 849809607, states[0] = -93.992727, states[40]= 0.000000
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Iteration: 853441748, states[0] = -93.973377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858203918, states[0] = -72.377642, states[40]= 0.000007
Saving checkpoint... 
Iteration: 862922617, states[0] = -93.963727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867597503, states[0] = -93.980986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871829148, states[0] = -93.965194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876147628, states[0] = -27.367222, states[40]= 0.002776
Saving checkpoint... 
Iteration: 879510363, states[0] = -93.956799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883041806, states[0] = -93.986118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886510867, states[0] = -93.971588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891298398, states[0] = -93.671971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896181141, states[0] = -93.960290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900450530, states[0] = -93.923556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904653045, states[0] = -93.968398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908171636, states[0] = -93.960380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911631636, states[0] = -93.956155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915278918, states[0] = -93.603614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920115558, states[0] = -93.961025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924843348, states[0] = -93.992119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929003150, states[0] = -93.962466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933153518, states[0] = -31.562577, states[40]= 0.002321
Saving checkpoint... 
Iteration: 936745690, states[0] = -93.992478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940294079, states[0] = -93.977442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943883272, states[0] = -93.964205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948561825, states[0] = -93.973405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953281032, states[0] = -93.959122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957586991, states[0] = -93.978929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961773724, states[0] = -93.966008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965395622, states[0] = -93.957994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968943643, states[0] = -93.954099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972444888, states[0] = -93.919233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976989159, states[0] = -93.962585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981809658, states[0] = -93.992521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986159461, states[0] = -93.960399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990430986, states[0] = -93.907821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993868980, states[0] = -93.991468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997395773, states[0] = -93.974387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000958859, states[0] = -93.962978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005704797, states[0] = -93.991221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010617059, states[0] = -93.956107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014944230, states[0] = -93.989285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019054164, states[0] = -93.961643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022587671, states[0] = -93.956307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026166648, states[0] = -41.167458, states[40]= 0.000864
Saving checkpoint... 
Iteration: 1029799607, states[0] = -93.992531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034256661, states[0] = -93.959249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038734001, states[0] = -93.992096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043372829, states[0] = -93.958083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047451054, states[0] = -93.923706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051418795, states[0] = -93.973676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054790740, states[0] = -93.965563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058226887, states[0] = -93.959529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061721853, states[0] = -93.955293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066317614, states[0] = -93.976530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070797818, states[0] = -93.954789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074861377, states[0] = -93.991516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078785190, states[0] = -93.965622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082876482, states[0] = -93.954298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086365792, states[0] = -93.828573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089955746, states[0] = -93.988791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094526760, states[0] = -93.956670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099227414, states[0] = -93.979314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103632354, states[0] = -93.955850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107706703, states[0] = -93.991141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111672399, states[0] = -93.967684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115084758, states[0] = -93.961102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118490042, states[0] = -93.956932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121959113, states[0] = -93.953776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126635746, states[0] = -93.968408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131216120, states[0] = -87.923258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135794038, states[0] = -93.965379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139793184, states[0] = -93.954710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143678151, states[0] = -93.989606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147118031, states[0] = -93.982983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150484553, states[0] = -93.971821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153958581, states[0] = -93.962743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158509082, states[0] = -93.955832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163290300, states[0] = -93.958700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167251687, states[0] = -93.487010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171324119, states[0] = -93.976171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174781296, states[0] = -93.965541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178317304, states[0] = -93.958406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181727545, states[0] = -93.955067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186372148, states[0] = -93.974752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191009426, states[0] = 30.639550, states[40]= 0.071857
Saving checkpoint... 
Iteration: 1195117890, states[0] = -93.982913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199063747, states[0] = -93.961238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202690776, states[0] = -93.955283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206893794, states[0] = -93.990502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211023996, states[0] = -93.961742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214480077, states[0] = -93.956865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217925533, states[0] = -93.953809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221506201, states[0] = -93.954514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226280049, states[0] = -93.958706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231021362, states[0] = -93.986305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235024218, states[0] = -93.961702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239100711, states[0] = 5.111400, states[40]= 0.003567
Saving checkpoint... 
Iteration: 1242704138, states[0] = -93.990825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246300622, states[0] = -93.976764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249924260, states[0] = -93.963098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254563860, states[0] = -93.973431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259260667, states[0] = -93.958855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263320272, states[0] = -93.734205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267490909, states[0] = -93.971480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271112551, states[0] = -93.960513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274749715, states[0] = -93.954776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278193384, states[0] = -62.203232, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1282930867, states[0] = -93.962948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287539928, states[0] = -93.966774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291690233, states[0] = -93.967050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295876336, states[0] = -93.953966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299343032, states[0] = -93.786491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302850197, states[0] = -93.991398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306392685, states[0] = -93.973990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311137414, states[0] = -19.979820, states[40]= 0.002008
Saving checkpoint... 
Iteration: 1315962995, states[0] = -93.962426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320221207, states[0] = -91.634018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324225620, states[0] = -93.979022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328339695, states[0] = -93.957952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331929746, states[0] = -93.953608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335453294, states[0] = -93.924858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340349343, states[0] = -93.957841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345178350, states[0] = -93.980574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349912365, states[0] = -93.953676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354086667, states[0] = -93.983776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358138917, states[0] = -93.960059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361744246, states[0] = -93.954676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365349648, states[0] = -93.799505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369455493, states[0] = -93.972215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374152063, states[0] = -30.521397, states[40]= 0.002481
Saving checkpoint... 
Iteration: 1378915436, states[0] = -93.963029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383099081, states[0] = 5.915835, states[40]= 0.003443
Saving checkpoint... 
Iteration: 1387363662, states[0] = -93.974679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391000997, states[0] = -93.961774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394508994, states[0] = -93.956345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397892689, states[0] = -93.953713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402112876, states[0] = -93.982768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406487515, states[0] = -93.956503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410414046, states[0] = -93.891101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414190164, states[0] = -93.980065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417914672, states[0] = -93.962980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421170347, states[0] = -93.959593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424516086, states[0] = -93.956240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427743754, states[0] = -93.954576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432272966, states[0] = -93.977331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436776392, states[0] = -93.954352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440491826, states[0] = -93.947562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444346344, states[0] = -93.975090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447557679, states[0] = -93.969612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451055923, states[0] = -93.960945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454400685, states[0] = -93.957184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458844602, states[0] = -93.991264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463281179, states[0] = -93.958324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467067517, states[0] = 19.096887, states[40]= 0.001009
Saving checkpoint... 
Iteration: 1471011521, states[0] = -93.986280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474433217, states[0] = -93.972632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477784082, states[0] = -93.965019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481135239, states[0] = -93.959911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485490266, states[0] = -93.946718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489963533, states[0] = -93.962146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494566113, states[0] = -93.973601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498495358, states[0] = -93.971010, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.828948
 - CaMKt in component CaMK (millimolar): 0.001317
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.678827
 - nass in component intracellular_ions (millimolar): 6.678952
 - ki in component intracellular_ions (millimolar): 145.185917
 - kss in component intracellular_ions (millimolar): 145.185907
 - cansr in component intracellular_ions (millimolar): 1.832465
 - cajsr in component intracellular_ions (millimolar): 1.832335
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004032
 - hf in component INa (dimensionless): 0.860101
 - hs in component INa (dimensionless): 0.860101
 - j in component INa (dimensionless): 0.860103
 - hsp in component INa (dimensionless): 0.689419
 - jp in component INa (dimensionless): 0.860103
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699971
 - hLp in component INaL (dimensionless): 0.504821
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.999227
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.999700
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999513
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005473
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000583
 - xs1 in component IKs (dimensionless): 0.014902
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997605
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:12:05 (212054): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_235.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_235_1_r1340823536_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_235_1_r1340823536_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.464748
     * GNaL_b in INaL: 0.006230
     * Gto_b in Ito: 0.084364
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031653
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.167381
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.622832
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035318
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1498495358
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.971010 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.828948
 - CaMKt in component CaMK (millimolar): 0.001317
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.678827
 - nass in component intracellular_ions (millimolar): 6.678952
 - ki in component intracellular_ions (millimolar): 145.185917
 - kss in component intracellular_ions (millimolar): 145.185907
 - cansr in component intracellular_ions (millimolar): 1.832465
 - cajsr in component intracellular_ions (millimolar): 1.832335
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004032
 - hf in component INa (dimensionless): 0.860101
 - hs in component INa (dimensionless): 0.860101
 - j in component INa (dimensionless): 0.860103
 - hsp in component INa (dimensionless): 0.689419
 - jp in component INa (dimensionless): 0.860103
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699971
 - hLp in component INaL (dimensionless): 0.504821
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.999227
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.999700
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999513
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005473
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000583
 - xs1 in component IKs (dimensionless): 0.014902
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997605
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:15:21 (264207): called boinc_finish(0)

</stderr_txt>
]]>


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