𝕏

Task 55531693

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_734_1
Workunit 26366906
Created 1 Jul 2024, 15:00:31 UTC
Sent 1 Jul 2024, 18:26:14 UTC
Report deadline 4 Jul 2024, 18:26:14 UTC
Received 2 Jul 2024, 18:27:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232190
Run time 2 hours 20 min 35 sec
CPU time 2 hours 17 min 45 sec
Validate state Valid
Credit 45.04
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.74 MB
Peak swap size 4.08 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_734.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_734_1_r872320743_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_734_1_r872320743_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.791033
     * GNaL_b in INaL: 0.006169
     * Gto_b in Ito: 0.084231
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031354
     * GKs_b in IKs: 0.001979
     * GK1_b in IK1: 0.161641
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.444217
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030278
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11129663, states[0] = -83.153840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 22239295, states[0] = -8.639565, states[40]= 0.000840
Saving checkpoint... 
Iteration: 33354691, states[0] = 27.578050, states[40]= 0.000321
Saving checkpoint... 
Iteration: 44447929, states[0] = -69.978662, states[40]= 0.000012
Saving checkpoint... 
Iteration: 55606094, states[0] = -60.043335, states[40]= 0.000038
Saving checkpoint... 
Iteration: 66730529, states[0] = -5.181179, states[40]= 0.000366
Saving checkpoint... 
Iteration: 77836718, states[0] = 29.279864, states[40]= 0.043373
Saving checkpoint... 
Iteration: 88937507, states[0] = -63.155897, states[40]= 0.000025
Saving checkpoint... 
Iteration: 99995917, states[0] = 28.230060, states[40]= 0.298879
Saving checkpoint... 
Iteration: 111064174, states[0] = -12.123994, states[40]= 0.000328
Saving checkpoint... 
Iteration: 122143084, states[0] = -84.907187, states[40]= 0.000001
Saving checkpoint... 
Iteration: 133242158, states[0] = -31.246374, states[40]= 0.000296
Saving checkpoint... 
Iteration: 144339909, states[0] = 28.497510, states[40]= 0.001159
Saving checkpoint... 
Iteration: 155466952, states[0] = -84.826698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 166568341, states[0] = -26.095650, states[40]= 0.000287
Saving checkpoint... 
Iteration: 177709885, states[0] = 4.245486, states[40]= 0.000134
Saving checkpoint... 
Iteration: 188825064, states[0] = 29.090786, states[40]= 0.053456
Saving checkpoint... 
Iteration: 199964581, states[0] = -84.853800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 211079756, states[0] = -47.153395, states[40]= 0.000123
Saving checkpoint... 
Iteration: 222189415, states[0] = 16.084919, states[40]= 0.000010
Saving checkpoint... 
Iteration: 233307234, states[0] = -85.000156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244415557, states[0] = -54.769550, states[40]= 0.000060
Saving checkpoint... 
Iteration: 255496873, states[0] = 28.023071, states[40]= 0.000694
Saving checkpoint... 
Iteration: 266602981, states[0] = -83.159279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277720103, states[0] = -20.795066, states[40]= 0.000265
Saving checkpoint... 
Iteration: 288813186, states[0] = 28.573567, states[40]= 0.107378
Saving checkpoint... 
Iteration: 299949015, states[0] = -84.762046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311078232, states[0] = -58.374084, states[40]= 0.000041
Saving checkpoint... 
Iteration: 322205447, states[0] = -6.382684, states[40]= 0.000332
Saving checkpoint... 
Iteration: 333320207, states[0] = 28.727789, states[40]= 0.001550
Saving checkpoint... 
Iteration: 344449599, states[0] = -84.837779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 355556942, states[0] = -36.216593, states[40]= 0.000257
Saving checkpoint... 
Iteration: 366695856, states[0] = -0.394005, states[40]= 0.000237
Saving checkpoint... 
Iteration: 377833740, states[0] = 20.237276, states[40]= 0.000005
Saving checkpoint... 
Iteration: 388985094, states[0] = 27.437673, states[40]= 0.000394
Saving checkpoint... 
Iteration: 400103307, states[0] = -84.708307, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411252378, states[0] = -81.676049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 422365205, states[0] = -10.585919, states[40]= 0.000330
Saving checkpoint... 
Iteration: 433464797, states[0] = 28.410175, states[40]= 0.133425
Saving checkpoint... 
Iteration: 444598049, states[0] = -84.686218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 455724421, states[0] = -50.349975, states[40]= 0.000092
Saving checkpoint... 
Iteration: 466868288, states[0] = -21.399727, states[40]= 0.000267
Saving checkpoint... 
Iteration: 478010289, states[0] = 6.694401, states[40]= 0.000089
Saving checkpoint... 
Iteration: 489157198, states[0] = 19.498986, states[40]= 0.000005
Saving checkpoint... 
Iteration: 500280588, states[0] = -84.984312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 511420734, states[0] = -84.544952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522527719, states[0] = -19.016021, states[40]= 0.000268
Saving checkpoint... 
Iteration: 533681301, states[0] = -2.723499, states[40]= 0.000285
Saving checkpoint... 
Iteration: 544817175, states[0] = 20.162448, states[40]= 0.000005
Saving checkpoint... 
Iteration: 555952044, states[0] = 28.285703, states[40]= 0.160437
Saving checkpoint... 
Iteration: 567069207, states[0] = -80.966570, states[40]= 0.000002
Saving checkpoint... 
Iteration: 578187702, states[0] = -17.402620, states[40]= 0.000274
Saving checkpoint... 
Iteration: 589341755, states[0] = -1.992981, states[40]= 0.000269
Saving checkpoint... 
Iteration: 600467283, states[0] = 26.004504, states[40]= 0.000119
Saving checkpoint... 
Iteration: 611548190, states[0] = -58.347210, states[40]= 0.000041
Saving checkpoint... 
Iteration: 622680979, states[0] = -14.112602, states[40]= 0.000301
Saving checkpoint... 
Iteration: 633778381, states[0] = 28.489035, states[40]= 0.120149
Saving checkpoint... 
Iteration: 644887795, states[0] = -72.362016, states[40]= 0.000007


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_734.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_734_1_r872320743_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_734_1_r872320743_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.791033
     * GNaL_b in INaL: 0.006169
     * Gto_b in Ito: 0.084231
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031354
     * GKs_b in IKs: 0.001979
     * GK1_b in IK1: 0.161641
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.444217
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030278
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 644887795
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -72.362016 (After loading)
 - states[40]: 0.000007 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 654658613, states[0] = 7.244853, states[40]= 0.000080
Saving checkpoint... 
Iteration: 665847682, states[0] = -20.387330, states[40]= 0.000267
Saving checkpoint... 
Iteration: 677025706, states[0] = -37.399740, states[40]= 0.000244
Saving checkpoint... 
Iteration: 688228521, states[0] = -83.472026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699439545, states[0] = 28.796406, states[40]= 0.081008
Saving checkpoint... 
Iteration: 710643219, states[0] = 14.360029, states[40]= 0.000016
Saving checkpoint... 
Iteration: 721855353, states[0] = -38.438664, states[40]= 0.000230
Saving checkpoint... 
Iteration: 733057424, states[0] = -83.482919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744246014, states[0] = -84.853297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 755471580, states[0] = 14.686574, states[40]= 0.000015
Saving checkpoint... 
Iteration: 766603840, states[0] = 29.575691, states[40]= 0.016061
Saving checkpoint... 
Iteration: 777809436, states[0] = 9.961381, states[40]= 0.000046
Saving checkpoint... 
Iteration: 789012285, states[0] = -34.447092, states[40]= 0.000274
Saving checkpoint... 
Iteration: 800218679, states[0] = -83.809446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811411882, states[0] = -84.919360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822653282, states[0] = -3.729716, states[40]= 0.000301
Saving checkpoint... 
Iteration: 833893086, states[0] = -84.676646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 845094422, states[0] = 29.425500, states[40]= 0.028777
Saving checkpoint... 
Iteration: 856258311, states[0] = 29.097027, states[40]= 0.053457
Saving checkpoint... 
Iteration: 867457382, states[0] = 16.632440, states[40]= 0.000008
Saving checkpoint... 
Iteration: 878623881, states[0] = 16.026839, states[40]= 0.000010
Saving checkpoint... 
Iteration: 889799793, states[0] = 8.792290, states[40]= 0.000059
Saving checkpoint... 
Iteration: 900960117, states[0] = 12.596628, states[40]= 0.000025
Saving checkpoint... 
Iteration: 912155097, states[0] = -18.523150, states[40]= 0.000270
Saving checkpoint... 
Iteration: 923327616, states[0] = -28.282309, states[40]= 0.000293
Saving checkpoint... 
Iteration: 934457837, states[0] = 11.847519, states[40]= 0.000030
Saving checkpoint... 
Iteration: 945626289, states[0] = 9.741115, states[40]= 0.000049
Saving checkpoint... 
Iteration: 956784337, states[0] = 14.984451, states[40]= 0.000013
Saving checkpoint... 
Iteration: 967954346, states[0] = 11.948077, states[40]= 0.000029
Saving checkpoint... 
Iteration: 979164605, states[0] = -40.578839, states[40]= 0.000203
Saving checkpoint... 
Iteration: 990404957, states[0] = 29.948958, states[40]= 0.587177
Saving checkpoint... 
Iteration: 1001590847, states[0] = 27.310674, states[40]= 0.000347
Saving checkpoint... 
Iteration: 1012802884, states[0] = -6.124832, states[40]= 0.000329
Saving checkpoint... 
Iteration: 1023981055, states[0] = -23.910992, states[40]= 0.000274
Saving checkpoint... 
Iteration: 1035171199, states[0] = -56.550268, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1046368817, states[0] = -84.575455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057563872, states[0] = 32.368809, states[40]= 0.839670
Saving checkpoint... 
Iteration: 1068769972, states[0] = 17.025394, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1079959931, states[0] = -2.612679, states[40]= 0.000280
Saving checkpoint... 
Iteration: 1091136006, states[0] = -16.798160, states[40]= 0.000280
Saving checkpoint... 
Iteration: 1102347282, states[0] = -79.270825, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1113552567, states[0] = -84.946443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124737643, states[0] = 29.452444, states[40]= 0.005392
Saving checkpoint... 
Iteration: 1135937394, states[0] = 12.057725, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1147100670, states[0] = 13.632504, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1158272969, states[0] = 8.781057, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1169458642, states[0] = -12.649266, states[40]= 0.000314
Saving checkpoint... 
Iteration: 1180662509, states[0] = -64.739898, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1191887101, states[0] = 28.142761, states[40]= 0.260892
Saving checkpoint... 
Iteration: 1203069104, states[0] = 27.923748, states[40]= 0.000615
Saving checkpoint... 
Iteration: 1214267457, states[0] = 8.713050, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1225454139, states[0] = -14.223240, states[40]= 0.000299
Saving checkpoint... 
Iteration: 1236638678, states[0] = -40.325338, states[40]= 0.000205
Saving checkpoint... 
Iteration: 1247807591, states[0] = -44.704178, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1259004747, states[0] = -83.410357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270189086, states[0] = -84.762225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1281395035, states[0] = 27.766891, states[40]= 0.000527
Saving checkpoint... 
Iteration: 1292603446, states[0] = -0.550757, states[40]= 0.000240
Saving checkpoint... 
Iteration: 1303776242, states[0] = -9.385522, states[40]= 0.000333
Saving checkpoint... 
Iteration: 1314927990, states[0] = 5.566143, states[40]= 0.000107
Saving checkpoint... 
Iteration: 1326108866, states[0] = -11.527595, states[40]= 0.000322
Saving checkpoint... 
Iteration: 1337308315, states[0] = -57.425205, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1348501334, states[0] = -84.339064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359739306, states[0] = 18.001807, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1370971458, states[0] = -57.202411, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1382136104, states[0] = -55.983135, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1393366016, states[0] = 28.401359, states[40]= 0.364086
Saving checkpoint... 
Iteration: 1404531139, states[0] = 28.698276, states[40]= 0.423394
Saving checkpoint... 
Iteration: 1415752397, states[0] = 4.581281, states[40]= 0.000126
Saving checkpoint... 
Iteration: 1426935432, states[0] = -16.298030, states[40]= 0.000283
Saving checkpoint... 
Iteration: 1438121266, states[0] = -43.874796, states[40]= 0.000160
Saving checkpoint... 
Iteration: 1449334771, states[0] = -84.702180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1460501190, states[0] = -84.716149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471664971, states[0] = -84.684574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1482845048, states[0] = -84.881383, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494082598, states[0] = 0.181964, states[40]= 0.000223
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.825782
 - CaMKt in component CaMK (millimolar): 0.216963
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.238671
 - nass in component intracellular_ions (millimolar): 7.239024
 - ki in component intracellular_ions (millimolar): 143.879580
 - kss in component intracellular_ions (millimolar): 143.879546
 - cansr in component intracellular_ions (millimolar): 3.332017
 - cajsr in component intracellular_ions (millimolar): 1.918060
 - cai in component intracellular_ions (millimolar): 0.000161
 - m in component INa (dimensionless): 0.009978
 - hf in component INa (dimensionless): 0.583406
 - hs in component INa (dimensionless): 0.582332
 - j in component INa (dimensionless): 0.550426
 - hsp in component INa (dimensionless): 0.330551
 - jp in component INa (dimensionless): 0.507047
 - mL in component INaL (dimensionless): 0.000336
 - hL in component INaL (dimensionless): 0.178846
 - hLp in component INaL (dimensionless): 0.072604
 - a in component Ito (dimensionless): 0.001230
 - iF in component Ito (dimensionless): 0.999234
 - iS in component Ito (dimensionless): 0.129115
 - ap in component Ito (dimensionless): 0.000627
 - iFp in component Ito (dimensionless): 0.999235
 - iSp in component Ito (dimensionless): 0.143982
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.673848
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.927202
 - jca in component ICaL (dimensionless): 0.909620
 - ffp in component ICaL (dimensionless): 0.998803
 - fcafp in component ICaL (dimensionless): 0.999935
 - nca in component ICaL (dimensionless): 0.042070
 - xrf in component IKr (dimensionless): 0.105673
 - xrs in component IKr (dimensionless): 0.874888
 - xs1 in component IKs (dimensionless): 0.573393
 - xs2 in component IKs (dimensionless): 0.007785
 - xk1 in component IK1 (dimensionless): 0.996743
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
10:26:14 (71552): called boinc_finish(0)

</stderr_txt>
]]>


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