𝕏

Task 55531553

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_834_0
Workunit 26366837
Created 1 Jul 2024, 15:00:26 UTC
Sent 1 Jul 2024, 18:26:23 UTC
Report deadline 4 Jul 2024, 18:26:23 UTC
Received 5 Jul 2024, 16:53:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239530
Run time 4 hours 41 min 20 sec
CPU time 1 hours 36 min 3 sec
Validate state Task was reported too late to validate
Credit 0.00
Device peak FLOPS 3.59 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.30 MB
Peak swap size 5.32 MB
Peak disk usage 1.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_834.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_834_0_r1714788200_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_834_0_r1714788200_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.891127
     * GNaL_b in INaL: 0.005507
     * Gto_b in Ito: 0.083302
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031751
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.162395
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.970786
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031158
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 3897438, states[0] = -86.813992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 7166592, states[0] = -86.783462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 10100440, states[0] = -10.413211, states[40]= 0.001987
Saving checkpoint... 
Iteration: 13616249, states[0] = -86.719741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16953445, states[0] = -86.702568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20601938, states[0] = -86.674952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23733501, states[0] = -86.651301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27143469, states[0] = -86.640558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30665461, states[0] = -86.627300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34074685, states[0] = 6.475854, states[40]= 0.004214
Saving checkpoint... 
Iteration: 37502347, states[0] = -86.593528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41638594, states[0] = -86.578891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44654109, states[0] = -86.579895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48252472, states[0] = -86.392837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51605439, states[0] = -86.553608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55292645, states[0] = -86.549938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58617825, states[0] = -86.548024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62104091, states[0] = -7.055915, states[40]= 0.002589
Saving checkpoint... 
Iteration: 65631493, states[0] = -86.528083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68687129, states[0] = -86.535347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72116119, states[0] = -16.011179, states[40]= 0.001182
Saving checkpoint... 
Iteration: 76003293, states[0] = 29.891264, states[40]= 0.173091
Saving checkpoint... 
Iteration: 79529585, states[0] = -86.512341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84027492, states[0] = 20.713275, states[40]= 0.005308
Saving checkpoint... 
Iteration: 86625965, states[0] = -86.514631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89353032, states[0] = -86.506099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93098008, states[0] = -86.507772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96802029, states[0] = -86.510105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100384639, states[0] = -86.456307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103901226, states[0] = -86.490911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107693306, states[0] = -86.490726, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_834.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_834_0_r1714788200_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_834_0_r1714788200_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.891127
     * GNaL_b in INaL: 0.005507
     * Gto_b in Ito: 0.083302
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031751
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.162395
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.970786
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031158
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 107693306
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.490726 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 109361755, states[0] = -86.493983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111744169, states[0] = -86.488404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115027982, states[0] = -86.497522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118550067, states[0] = -86.491308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121451882, states[0] = -86.487908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124679220, states[0] = -86.496956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128980121, states[0] = -86.493789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132080622, states[0] = 6.149400, states[40]= 0.004128
Saving checkpoint... 
Iteration: 135359774, states[0] = -86.485241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138213736, states[0] = -86.248223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141630987, states[0] = -86.480364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145598925, states[0] = -86.479930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148942928, states[0] = -86.490085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152304410, states[0] = -86.379928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155584800, states[0] = -86.478426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159020755, states[0] = -86.487076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161955978, states[0] = -86.474290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164506439, states[0] = -86.475607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168336144, states[0] = -86.407072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172365510, states[0] = -86.427021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175878594, states[0] = -86.473347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179459739, states[0] = -86.477311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183590247, states[0] = -86.475376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188002272, states[0] = 35.731839, states[40]= 0.136958
Saving checkpoint... 
Iteration: 191972451, states[0] = -86.471486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196182224, states[0] = -75.489938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199967351, states[0] = -86.471075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203090957, states[0] = -86.482057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206390337, states[0] = -86.438203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210507683, states[0] = -86.472623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213884781, states[0] = -86.471057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217348217, states[0] = -86.476886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221328157, states[0] = -86.477078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224535936, states[0] = -86.476244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227715483, states[0] = -86.472051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231377705, states[0] = -86.476039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234983565, states[0] = -86.483144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238757380, states[0] = -86.485986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242956038, states[0] = -86.483512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247029752, states[0] = -86.482011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250369410, states[0] = -86.425992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253675407, states[0] = -86.471938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256933038, states[0] = -86.483723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259913360, states[0] = -86.469838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263969143, states[0] = -86.469408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267194328, states[0] = -86.478551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270542740, states[0] = -86.476311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273948283, states[0] = -86.469450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277311582, states[0] = -86.476415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280474473, states[0] = -86.464948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283258767, states[0] = -86.477260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286379974, states[0] = -86.431492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289612665, states[0] = -86.472254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292793423, states[0] = -86.485279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295918426, states[0] = -86.469508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299327460, states[0] = -86.476020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302635457, states[0] = -86.483119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305904142, states[0] = -86.469564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309561996, states[0] = -86.472732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313284542, states[0] = -86.476669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317098445, states[0] = -86.480090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320895549, states[0] = -86.483944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324353517, states[0] = -86.415515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328394969, states[0] = -86.438717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332595605, states[0] = -86.480834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336015553, states[0] = 21.951432, states[40]= 0.014013
Saving checkpoint... 
Iteration: 339819952, states[0] = -86.470112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343896910, states[0] = -86.469510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347619046, states[0] = -86.471991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351214548, states[0] = -86.477806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354358759, states[0] = -86.418906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358583913, states[0] = -86.479938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362415817, states[0] = -86.447391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366136899, states[0] = -31.317724, states[40]= 0.000430
Saving checkpoint... 
Iteration: 369504431, states[0] = -86.473310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372990072, states[0] = -86.482133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376026643, states[0] = 21.098477, states[40]= 0.005498
Saving checkpoint... 
Iteration: 379339114, states[0] = -86.475655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383108687, states[0] = -86.479777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386964299, states[0] = -86.482617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390441012, states[0] = -86.455929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394052537, states[0] = 15.308342, states[40]= 0.004235
Saving checkpoint... 
Iteration: 397265219, states[0] = -86.476863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400359659, states[0] = -86.419439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404084757, states[0] = 4.704471, states[40]= 0.004048
Saving checkpoint... 
Iteration: 407049134, states[0] = -86.480941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410325773, states[0] = -86.394078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414292989, states[0] = -86.360732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418327667, states[0] = -86.395712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421784455, states[0] = -86.470330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424857179, states[0] = -86.484394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428254062, states[0] = -86.307251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431899858, states[0] = -86.469414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435637201, states[0] = -86.471727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438876052, states[0] = -86.484120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442519050, states[0] = -86.472783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446247617, states[0] = -86.297083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449612837, states[0] = -86.471984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454168907, states[0] = -59.858259, states[40]= 0.000005
Saving checkpoint... 
Iteration: 457800974, states[0] = -86.470177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461769359, states[0] = -86.470447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465023176, states[0] = -86.481435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468580420, states[0] = -86.479599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472188195, states[0] = -81.875373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475307578, states[0] = -86.476120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479377198, states[0] = -86.475022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483001987, states[0] = -86.481849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486664250, states[0] = -86.483938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490175318, states[0] = -66.773097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493879802, states[0] = -86.469544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497751023, states[0] = -86.470600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500723707, states[0] = -86.484991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504075444, states[0] = 8.256452, states[40]= 0.004193
Saving checkpoint... 
Iteration: 507657092, states[0] = -86.471500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511516409, states[0] = -86.473097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514513637, states[0] = -86.471945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517656847, states[0] = -86.471500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521361206, states[0] = -86.475256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525232538, states[0] = -86.477395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529517303, states[0] = -86.473082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532699519, states[0] = -86.484699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536663530, states[0] = -86.483906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540284759, states[0] = -86.350685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543874957, states[0] = -86.469569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546966606, states[0] = -86.482520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549769163, states[0] = -86.470428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553079261, states[0] = -86.480300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556144367, states[0] = -37.625507, states[40]= 0.000185
Saving checkpoint... 
Iteration: 559025729, states[0] = -86.481363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562583588, states[0] = -86.479829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566700316, states[0] = -86.484705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570068376, states[0] = 10.650774, states[40]= 0.004244
Saving checkpoint... 
Iteration: 573931008, states[0] = -86.469157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577557512, states[0] = -86.472583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580899599, states[0] = -86.483715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584700163, states[0] = -86.484699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588421676, states[0] = -86.449477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592697125, states[0] = -86.484650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595757812, states[0] = -86.470519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599132092, states[0] = -86.479254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602378956, states[0] = -86.430638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606233016, states[0] = -86.273631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610521116, states[0] = -86.473047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613704363, states[0] = -86.471010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616880180, states[0] = -86.484017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620445217, states[0] = -86.457112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624112700, states[0] = -11.272263, states[40]= 0.001788
Saving checkpoint... 
Iteration: 627920600, states[0] = -86.469220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631472482, states[0] = -86.473640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634653969, states[0] = -86.483588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638153349, states[0] = -45.398434, states[40]= 0.000056
Saving checkpoint... 
Iteration: 641478450, states[0] = -86.473559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645543683, states[0] = -86.472735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648530976, states[0] = -86.474402, states[40]= 0.000000
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Iteration: 673870283, states[0] = -86.469580, states[40]= 0.000000
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Iteration: 687181795, states[0] = -86.478291, states[40]= 0.000000
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Iteration: 690730549, states[0] = -86.485004, states[40]= 0.000000
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Iteration: 704237643, states[0] = -86.281014, states[40]= 0.000000
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Iteration: 730147060, states[0] = -39.927375, states[40]= 0.000131
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Iteration: 733579410, states[0] = -86.472299, states[40]= 0.000000
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Iteration: 736996819, states[0] = -86.481900, states[40]= 0.000000
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Iteration: 740469945, states[0] = -86.463537, states[40]= 0.000000
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Iteration: 743730302, states[0] = -86.470741, states[40]= 0.000000
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Iteration: 750732062, states[0] = -86.485003, states[40]= 0.000000
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Iteration: 753865283, states[0] = -86.469603, states[40]= 0.000000
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Iteration: 757462128, states[0] = -86.473754, states[40]= 0.000000
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Iteration: 760820180, states[0] = -86.484756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764422608, states[0] = -86.449778, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_834.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_834_0_r1714788200_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_834_0_r1714788200_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.891127
     * GNaL_b in INaL: 0.005507
     * Gto_b in Ito: 0.083302
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031751
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.162395
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.970786
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031158
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 764422608
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.449778 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 766199292, states[0] = -85.911735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768909472, states[0] = -86.483514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771296736, states[0] = -86.476240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774434799, states[0] = -86.453902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777419403, states[0] = -86.474343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780135710, states[0] = -30.317775, states[40]= 0.000482
Saving checkpoint... 
Iteration: 783691064, states[0] = -86.471106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787415094, states[0] = -86.474403, states[40]= 0.000000
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Iteration: 790919511, states[0] = -86.483337, states[40]= 0.000000
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Iteration: 794937111, states[0] = -86.483022, states[40]= 0.000000
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Iteration: 797318063, states[0] = -86.475885, states[40]= 0.000000
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Iteration: 798586288, states[0] = -86.479991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801484113, states[0] = -86.473454, states[40]= 0.000000
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Iteration: 803847387, states[0] = -86.469732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806898650, states[0] = -86.483688, states[40]= 0.000000
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Iteration: 810800169, states[0] = -86.484915, states[40]= 0.000000
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Iteration: 814205084, states[0] = -86.165732, states[40]= 0.000000
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Iteration: 817902686, states[0] = -86.469312, states[40]= 0.000000
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Iteration: 821288336, states[0] = -86.476371, states[40]= 0.000000
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Iteration: 825491661, states[0] = -86.473351, states[40]= 0.000000
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Iteration: 829574400, states[0] = -86.472338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833369170, states[0] = -86.475074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837286973, states[0] = -86.476391, states[40]= 0.000000
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Iteration: 841090124, states[0] = -86.480030, states[40]= 0.000000
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Iteration: 844868823, states[0] = -86.484143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847780950, states[0] = -86.470269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850845973, states[0] = -86.484450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854518267, states[0] = -86.472583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858027603, states[0] = 20.957317, states[40]= 0.005333
Saving checkpoint... 
Iteration: 860975457, states[0] = -86.482291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864177247, states[0] = -69.060524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867961451, states[0] = -86.468893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871179671, states[0] = -86.478296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874794784, states[0] = -86.484939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878632155, states[0] = -86.482692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882164548, states[0] = -55.598663, states[40]= 0.000010
Saving checkpoint... 
Iteration: 885162251, states[0] = -86.478621, states[40]= 0.000000
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Iteration: 888402476, states[0] = -86.441855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891565959, states[0] = -86.472425, states[40]= 0.000000
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Iteration: 894645980, states[0] = -86.483256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898741717, states[0] = -86.485022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902625146, states[0] = -86.482360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905876080, states[0] = -86.469492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908914507, states[0] = -86.483401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912402510, states[0] = -86.441865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915955659, states[0] = -86.468923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919714507, states[0] = -86.470855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923346532, states[0] = -86.475407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927432650, states[0] = -86.474128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931191249, states[0] = -86.478069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935433311, states[0] = -86.474117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938902073, states[0] = -86.483606, states[40]= 0.000000
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Iteration: 942799766, states[0] = -86.484893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945719348, states[0] = -86.470804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949067463, states[0] = -86.480459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952503553, states[0] = -86.470220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955984281, states[0] = -86.468727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959471003, states[0] = -86.473597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963422906, states[0] = -86.474258, states[40]= 0.000000
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Iteration: 973542515, states[0] = -86.472687, states[40]= 0.000000
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Iteration: 977035966, states[0] = -86.481081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980936815, states[0] = -86.482992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984999160, states[0] = -86.481807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988184607, states[0] = -78.222129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991713066, states[0] = -86.470855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995045168, states[0] = -86.480894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998662756, states[0] = -86.483796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002266303, states[0] = -86.325569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005895022, states[0] = -86.469332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009433080, states[0] = -86.474106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012513844, states[0] = -86.471882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016097677, states[0] = -1.305356, states[40]= 0.003510
Saving checkpoint... 
Iteration: 1018987246, states[0] = -86.482033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022513551, states[0] = -86.471835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026523676, states[0] = -86.473335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030420984, states[0] = -86.449143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034037745, states[0] = 19.005237, states[40]= 0.004445
Saving checkpoint... 
Iteration: 1037407371, states[0] = -86.474467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041109001, states[0] = -86.479621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044367995, states[0] = -86.424409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047560378, states[0] = -86.472460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051227141, states[0] = -86.477391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054530034, states[0] = -86.474200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057785542, states[0] = -86.470190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061888824, states[0] = -86.469367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065084542, states[0] = -86.480099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068316359, states[0] = -86.385362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071578232, states[0] = -86.472248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075395899, states[0] = -86.474628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078827797, states[0] = -86.484618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082346107, states[0] = -86.410098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085926342, states[0] = -86.469093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089719300, states[0] = -86.470778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092910031, states[0] = -86.483443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096412603, states[0] = -86.445970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100212379, states[0] = -86.234079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103544698, states[0] = -86.472636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106760333, states[0] = -86.485014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110351710, states[0] = -86.414035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113283802, states[0] = -86.476392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116862178, states[0] = -86.484186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120192702, states[0] = -84.584249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123464569, states[0] = -86.473652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127177639, states[0] = -86.478285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130095479, states[0] = -0.158770, states[40]= 0.003651
Saving checkpoint... 
Iteration: 1133452462, states[0] = -86.473814, states[40]= 0.000000
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Iteration: 1136667172, states[0] = -86.483896, states[40]= 0.000000
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Iteration: 1139511461, states[0] = -86.473039, states[40]= 0.000000
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Iteration: 1143130401, states[0] = -86.479184, states[40]= 0.000000
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Iteration: 1146577982, states[0] = -86.479269, states[40]= 0.000000
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Iteration: 1149839683, states[0] = -86.469727, states[40]= 0.000000
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Iteration: 1153133998, states[0] = -86.479113, states[40]= 0.000000
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Iteration: 1156408038, states[0] = -86.444134, states[40]= 0.000000
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Iteration: 1159936885, states[0] = -86.469005, states[40]= 0.000000
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Iteration: 1163406166, states[0] = -86.474461, states[40]= 0.000000
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Iteration: 1167031310, states[0] = -86.481137, states[40]= 0.000000
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Iteration: 1169223790, states[0] = -86.477429, states[40]= 0.000000
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Iteration: 1177283710, states[0] = -86.476382, states[40]= 0.000000
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Iteration: 1181253583, states[0] = -86.476899, states[40]= 0.000000
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Iteration: 1184949468, states[0] = -86.482721, states[40]= 0.000000
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Iteration: 1188132630, states[0] = -27.740375, states[40]= 0.000617
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Iteration: 1190674741, states[0] = -86.484083, states[40]= 0.000000
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Iteration: 1194391401, states[0] = -86.436791, states[40]= 0.000000
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Iteration: 1218560094, states[0] = -86.477635, states[40]= 0.000000
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Iteration: 1222021715, states[0] = 21.667171, states[40]= 0.006984
Saving checkpoint... 
Iteration: 1225023915, states[0] = -86.481273, states[40]= 0.000000
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Iteration: 1249707213, states[0] = -86.470862, states[40]= 0.000000
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Iteration: 1253042290, states[0] = -86.480903, states[40]= 0.000000
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Iteration: 1256420664, states[0] = -86.448984, states[40]= 0.000000
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Iteration: 1260054899, states[0] = 14.662992, states[40]= 0.004240
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Iteration: 1267620813, states[0] = -86.471737, states[40]= 0.000000
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Iteration: 1365523744, states[0] = -86.472843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368739628, states[0] = -86.484925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371738574, states[0] = -86.470546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375311678, states[0] = -86.475880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379280369, states[0] = -86.476400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383143318, states[0] = -86.478889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386187529, states[0] = -81.290840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389581361, states[0] = -86.472152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392928545, states[0] = -86.483063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395879709, states[0] = -86.469372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399265562, states[0] = -86.476650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403412409, states[0] = -86.474325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408145000, states[0] = -38.164577, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1411274820, states[0] = -86.476489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414196389, states[0] = -85.560363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417176433, states[0] = -86.478253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420649380, states[0] = -86.483280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423496863, states[0] = -86.473171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427267528, states[0] = -86.476610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430209165, states[0] = -86.216511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433849128, states[0] = -86.469599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436918269, states[0] = -86.483236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441099582, states[0] = -86.479730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445142107, states[0] = -86.478901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448429625, states[0] = -86.452079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451619717, states[0] = -86.471714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455371203, states[0] = -86.474925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459363596, states[0] = -86.475041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463316318, states[0] = -86.475787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466700060, states[0] = -86.484531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470252227, states[0] = -86.304176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473756669, states[0] = -86.470363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477176862, states[0] = -86.478234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479906003, states[0] = -86.469163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483812674, states[0] = -86.469882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487003992, states[0] = -86.481617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490755018, states[0] = -86.484940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493921483, states[0] = -86.469049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497140047, states[0] = -86.478931, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.344492
 - CaMKt in component CaMK (millimolar): 0.000890
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.041287
 - nass in component intracellular_ions (millimolar): 6.041332
 - ki in component intracellular_ions (millimolar): 145.954524
 - kss in component intracellular_ions (millimolar): 145.954513
 - cansr in component intracellular_ions (millimolar): 1.250495
 - cajsr in component intracellular_ions (millimolar): 1.250631
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008568
 - hf in component INa (dimensionless): 0.642527
 - hs in component INa (dimensionless): 0.642528
 - j in component INa (dimensionless): 0.642531
 - hsp in component INa (dimensionless): 0.393560
 - jp in component INa (dimensionless): 0.642532
 - mL in component INaL (dimensionless): 0.000252
 - hL in component INaL (dimensionless): 0.461988
 - hLp in component INaL (dimensionless): 0.272573
 - a in component Ito (dimensionless): 0.001110
 - iF in component Ito (dimensionless): 0.999417
 - iS in component Ito (dimensionless): 0.985476
 - ap in component Ito (dimensionless): 0.000566
 - iFp in component Ito (dimensionless): 0.999417
 - iSp in component Ito (dimensionless): 0.991589
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997501
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001269
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020555
 - xs1 in component IKs (dimensionless): 0.037177
 - xs2 in component IKs (dimensionless): 0.000229
 - xk1 in component IK1 (dimensionless): 0.997139
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:53:42 (36088): called boinc_finish(0)

</stderr_txt>
]]>


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