𝕏

Task 55531160

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_234_1
Workunit 26366640
Created 1 Jul 2024, 15:00:11 UTC
Sent 1 Jul 2024, 18:26:14 UTC
Report deadline 4 Jul 2024, 18:26:14 UTC
Received 2 Jul 2024, 14:24:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232190
Run time 2 hours 19 min 16 sec
CPU time 2 hours 16 min 42 sec
Validate state Valid
Credit 44.13
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.69 MB
Peak swap size 4.08 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_234.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_234_1_r247009305_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_234_1_r247009305_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.701878
     * GNaL_b in INaL: 0.005458
     * Gto_b in Ito: 0.085059
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031655
     * GKs_b in IKs: 0.001952
     * GK1_b in IK1: 0.167264
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.903653
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031651
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11181859, states[0] = -94.102433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22377091, states[0] = -93.913617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33552735, states[0] = -93.991979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44756693, states[0] = -94.004470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55949405, states[0] = -93.968250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67104087, states[0] = -93.989038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78295315, states[0] = -93.679494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89477127, states[0] = -93.975931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100659861, states[0] = -93.995033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111841539, states[0] = -93.967697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123043729, states[0] = -93.990663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134192969, states[0] = -66.877358, states[40]= 0.000016
Saving checkpoint... 
Iteration: 145377154, states[0] = -93.978771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156581718, states[0] = -93.985042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167774026, states[0] = -93.968942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178953563, states[0] = -93.994050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190116960, states[0] = -6.616014, states[40]= 0.003118
Saving checkpoint... 
Iteration: 201310910, states[0] = -93.980783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212471181, states[0] = -93.945846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223641929, states[0] = -93.971624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234824639, states[0] = -93.997750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246007768, states[0] = 30.054005, states[40]= 0.129138
Saving checkpoint... 
Iteration: 257181343, states[0] = -93.985180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268344943, states[0] = -93.804207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279525718, states[0] = -93.974318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290722396, states[0] = -93.997686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301920272, states[0] = -93.966000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313102759, states[0] = -93.988018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324280579, states[0] = -93.627902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335474429, states[0] = -93.975552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346658631, states[0] = -93.994508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357855935, states[0] = -93.966979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369055252, states[0] = -93.989729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380295902, states[0] = -93.680442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391462206, states[0] = -93.975755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402682002, states[0] = -93.995888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413854689, states[0] = -93.966866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425043421, states[0] = -93.990055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436176558, states[0] = -53.041475, states[40]= 0.000149
Saving checkpoint... 
Iteration: 447375267, states[0] = -93.978161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458542461, states[0] = -93.975011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469776681, states[0] = -93.968193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480978092, states[0] = -93.992436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492151236, states[0] = -33.354474, states[40]= 0.001777
Saving checkpoint... 
Iteration: 503337176, states[0] = -93.979217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514558292, states[0] = -93.979103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525720059, states[0] = -93.969200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536907276, states[0] = -93.994822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548096040, states[0] = 6.022469, states[40]= 0.003052
Saving checkpoint... 
Iteration: 559314517, states[0] = -93.979813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570503932, states[0] = -93.961203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581676856, states[0] = -93.969987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592848972, states[0] = -93.996369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604021326, states[0] = 31.397674, states[40]= 0.001230
Saving checkpoint... 
Iteration: 615236902, states[0] = -93.982313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626438193, states[0] = -93.922516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637656625, states[0] = -93.970298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648848086, states[0] = -93.996255, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_234.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_234_1_r247009305_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_234_1_r247009305_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.701878
     * GNaL_b in INaL: 0.005458
     * Gto_b in Ito: 0.085059
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031655
     * GKs_b in IKs: 0.001952
     * GK1_b in IK1: 0.167264
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.903653
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031651
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 648848086
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.996255 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 660152638, states[0] = -34.408866, states[40]= 0.001620
Saving checkpoint... 
Iteration: 671480651, states[0] = -93.974569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682785645, states[0] = -93.997184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694072642, states[0] = 16.199812, states[40]= 0.001216
Saving checkpoint... 
Iteration: 705365099, states[0] = -93.977850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716678100, states[0] = -93.994913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728023603, states[0] = 31.168980, states[40]= 0.000605
Saving checkpoint... 
Iteration: 739324854, states[0] = -93.979042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750608761, states[0] = -93.988170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761901182, states[0] = -93.965210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773204276, states[0] = -93.983097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784497678, states[0] = -93.957969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795809675, states[0] = -93.966770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807098582, states[0] = -93.986987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818395471, states[0] = -93.880433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829700206, states[0] = -93.968883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841022767, states[0] = -93.989854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852341957, states[0] = -93.796875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863666207, states[0] = -93.969538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874966388, states[0] = -93.991922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886243398, states[0] = -93.465328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897526551, states[0] = -93.972802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908816263, states[0] = -93.996276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920117259, states[0] = -6.841637, states[40]= 0.003080
Saving checkpoint... 
Iteration: 931433519, states[0] = -93.975260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942718419, states[0] = -93.996015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954043473, states[0] = 26.560848, states[40]= 0.000243
Saving checkpoint... 
Iteration: 965342355, states[0] = -93.977935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976676605, states[0] = -93.994199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987995867, states[0] = -93.963125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999297669, states[0] = -93.979304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010600368, states[0] = -93.986283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021914218, states[0] = -93.964359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033224745, states[0] = -93.981733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044544682, states[0] = -93.974230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055842600, states[0] = -93.965531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067143481, states[0] = -93.984640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078485043, states[0] = -93.951247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089805180, states[0] = -93.966143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101091118, states[0] = -93.986565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112403658, states[0] = -93.889067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123681330, states[0] = -93.968577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135006031, states[0] = -93.989791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146270506, states[0] = -93.586860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157553661, states[0] = -93.971482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168862322, states[0] = -93.994640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180152908, states[0] = -34.610755, states[40]= 0.001590
Saving checkpoint... 
Iteration: 1191407286, states[0] = -93.975397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202666683, states[0] = -93.993024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213988628, states[0] = -93.962689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225269686, states[0] = -93.979701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236586702, states[0] = -93.983416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247916152, states[0] = -93.963779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259236965, states[0] = -93.980754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270586069, states[0] = -93.983218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281918679, states[0] = -93.963655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293256477, states[0] = -93.979991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304593288, states[0] = -93.984414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315897907, states[0] = -93.963924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327215600, states[0] = -93.981349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338469000, states[0] = -93.941860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349745733, states[0] = -93.966679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361088499, states[0] = -93.986038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372399088, states[0] = -93.883308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383724647, states[0] = -93.967028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395062811, states[0] = -93.986956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406410858, states[0] = -93.895988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417752323, states[0] = -93.966381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429081559, states[0] = -93.986144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440426500, states[0] = -93.910785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451772879, states[0] = -93.965890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463108523, states[0] = -93.985018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474464289, states[0] = -93.938695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485753415, states[0] = -93.966195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497085657, states[0] = -93.985820, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.837790
 - CaMKt in component CaMK (millimolar): 0.002097
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.762903
 - nass in component intracellular_ions (millimolar): 6.763027
 - ki in component intracellular_ions (millimolar): 145.093645
 - kss in component intracellular_ions (millimolar): 145.093635
 - cansr in component intracellular_ions (millimolar): 1.841801
 - cajsr in component intracellular_ions (millimolar): 1.841651
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004029
 - hf in component INa (dimensionless): 0.860276
 - hs in component INa (dimensionless): 0.860277
 - j in component INa (dimensionless): 0.860281
 - hsp in component INa (dimensionless): 0.689733
 - jp in component INa (dimensionless): 0.860283
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.700252
 - hLp in component INaL (dimensionless): 0.504605
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.991438
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.996571
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996479
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005364
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008064
 - xs1 in component IKs (dimensionless): 0.041195
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997603
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:24:17 (68539): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge