𝕏

Task 55530665

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_500-conf_433_0
Workunit 26366393
Created 1 Jul 2024, 15:00:00 UTC
Sent 1 Jul 2024, 18:23:15 UTC
Report deadline 4 Jul 2024, 18:23:15 UTC
Received 1 Jul 2024, 23:59:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 51 min 11 sec
CPU time 1 hours 44 min 11 sec
Validate state Valid
Credit 44.89
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.83 MB
Peak swap size 4.13 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_500-conf_433.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_500-conf_433_0_r709880087_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_500-conf_433_0_r709880087_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.695025
     * GNaL_b in INaL: 0.005876
     * Gto_b in Ito: 0.086467
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031846
     * GKs_b in IKs: 0.001904
     * GK1_b in IK1: 0.162096
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.137744
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036227
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12197877, states[0] = -84.638847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26590045, states[0] = -14.904078, states[40]= 0.000283
Saving checkpoint... 
Iteration: 38419507, states[0] = -84.368206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50768417, states[0] = 31.122797, states[40]= 0.003139
Saving checkpoint... 
Iteration: 62497645, states[0] = -84.887393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73930750, states[0] = -84.502961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85925929, states[0] = -84.461264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97153523, states[0] = -83.998666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109584815, states[0] = -10.107063, states[40]= 0.000220
Saving checkpoint... 
Iteration: 121708155, states[0] = -84.716654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 132759114, states[0] = 30.195327, states[40]= 0.091630
Saving checkpoint... 
Iteration: 143701269, states[0] = -84.672619, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155440509, states[0] = -84.593621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 167071748, states[0] = 2.713364, states[40]= 0.000133
Saving checkpoint... 
Iteration: 176400869, states[0] = -83.759229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186943737, states[0] = -84.617888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198076574, states[0] = -1.379451, states[40]= 0.000189
Saving checkpoint... 
Iteration: 208932800, states[0] = -84.527866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219564126, states[0] = 8.237494, states[40]= 0.000063
Saving checkpoint... 
Iteration: 229580870, states[0] = -5.660075, states[40]= 0.000224
Saving checkpoint... 
Iteration: 239329106, states[0] = -3.816990, states[40]= 0.000214
Saving checkpoint... 
Iteration: 249591425, states[0] = -18.497370, states[40]= 0.000162
Saving checkpoint... 
Iteration: 260074508, states[0] = 0.447059, states[40]= 0.000165
Saving checkpoint... 
Iteration: 270199383, states[0] = -84.656040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279798301, states[0] = 17.901462, states[40]= 0.000009
Saving checkpoint... 
Iteration: 288978972, states[0] = -84.822824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 299047358, states[0] = 18.425776, states[40]= 0.000008
Saving checkpoint... 
Iteration: 310099570, states[0] = -28.503273, states[40]= 0.000161
Saving checkpoint... 
Iteration: 321579863, states[0] = -4.590519, states[40]= 0.000219
Saving checkpoint... 
Iteration: 332208486, states[0] = -84.713232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 343041058, states[0] = 21.803307, states[40]= 0.000004
Saving checkpoint... 
Iteration: 354120865, states[0] = -53.616835, states[40]= 0.000023
Saving checkpoint... 
Iteration: 365346501, states[0] = -24.787791, states[40]= 0.000159
Saving checkpoint... 
Iteration: 376202607, states[0] = -84.674112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 386292375, states[0] = 21.115740, states[40]= 0.000005
Saving checkpoint... 
Iteration: 398088219, states[0] = -14.434803, states[40]= 0.000186
Saving checkpoint... 
Iteration: 408915158, states[0] = -84.338221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420495275, states[0] = -84.883487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431976718, states[0] = -84.807259, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442734894, states[0] = -84.842830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 454143908, states[0] = -81.587286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466019305, states[0] = 30.829683, states[40]= 0.002277
Saving checkpoint... 
Iteration: 479206792, states[0] = -84.697350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489740713, states[0] = -84.864201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503381134, states[0] = -66.698671, states[40]= 0.000004
Saving checkpoint... 
Iteration: 514654699, states[0] = -84.068864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526064488, states[0] = 7.997435, states[40]= 0.000065
Saving checkpoint... 
Iteration: 535365202, states[0] = -46.885071, states[40]= 0.000049
Saving checkpoint... 
Iteration: 545408266, states[0] = -84.205706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556225515, states[0] = -84.797051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564848814, states[0] = -27.580941, states[40]= 0.000161
Saving checkpoint... 
Iteration: 573466203, states[0] = -84.748955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 584196814, states[0] = -84.626211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 593153463, states[0] = -83.989265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601536009, states[0] = 24.352754, states[40]= 0.000008
Saving checkpoint... 
Iteration: 611741835, states[0] = -84.863991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622668597, states[0] = -84.372327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633920458, states[0] = -84.392598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644742337, states[0] = -84.864660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 653511056, states[0] = 30.799561, states[40]= 0.045256
Saving checkpoint... 
Iteration: 663374194, states[0] = -57.654523, states[40]= 0.000014
Saving checkpoint... 
Iteration: 672063745, states[0] = 8.501868, states[40]= 0.000060
Saving checkpoint... 
Iteration: 681714134, states[0] = -84.733522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691630914, states[0] = -66.379228, states[40]= 0.000005
Saving checkpoint... 
Iteration: 703115573, states[0] = -47.311149, states[40]= 0.000047
Saving checkpoint... 
Iteration: 714646456, states[0] = -82.751503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726239783, states[0] = -84.852034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738623516, states[0] = -56.812118, states[40]= 0.000016
Saving checkpoint... 
Iteration: 750042345, states[0] = 21.136865, states[40]= 0.000005
Saving checkpoint... 
Iteration: 761514703, states[0] = 31.305657, states[40]= 0.012017
Saving checkpoint... 
Iteration: 773264462, states[0] = 31.299322, states[40]= 0.013115
Saving checkpoint... 
Iteration: 784925025, states[0] = -84.434076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797208823, states[0] = -84.698197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809271450, states[0] = 30.311289, states[40]= 0.001053
Saving checkpoint... 
Iteration: 821008885, states[0] = 30.114025, states[40]= 0.099521
Saving checkpoint... 
Iteration: 831949869, states[0] = -84.638712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842593785, states[0] = -21.420906, states[40]= 0.000156
Saving checkpoint... 
Iteration: 854491636, states[0] = -84.854412, states[40]= 0.000001
Saving checkpoint... 
Iteration: 866405145, states[0] = -84.077118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878337164, states[0] = -13.081200, states[40]= 0.000196
Saving checkpoint... 
Iteration: 890218924, states[0] = -84.751905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 902237955, states[0] = -84.838482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 914286219, states[0] = 24.254596, states[40]= 0.000007
Saving checkpoint... 
Iteration: 925764927, states[0] = 31.310488, states[40]= 0.011077
Saving checkpoint... 
Iteration: 937137771, states[0] = -75.720610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948791111, states[0] = 21.784661, states[40]= 0.000004
Saving checkpoint... 
Iteration: 960590901, states[0] = -17.800640, states[40]= 0.000165
Saving checkpoint... 
Iteration: 972688372, states[0] = -84.546880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984663023, states[0] = -84.285774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996941524, states[0] = -84.571155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1007935752, states[0] = -84.523790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1019419103, states[0] = -84.363176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030142425, states[0] = -80.530064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042241973, states[0] = -84.848841, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054666312, states[0] = -84.328753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065977683, states[0] = -84.788577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1077903028, states[0] = -83.935533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089181496, states[0] = -84.483652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100733866, states[0] = -84.814551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1112251351, states[0] = 36.405050, states[40]= 0.989513
Saving checkpoint... 
Iteration: 1124243944, states[0] = -84.853115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1135565459, states[0] = 7.345069, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1147010668, states[0] = 30.698705, states[40]= 0.052089
Saving checkpoint... 
Iteration: 1158662583, states[0] = -84.272152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169036731, states[0] = 24.006649, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1180405200, states[0] = -84.066730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191248525, states[0] = -84.866762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202352635, states[0] = -32.113153, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1213479823, states[0] = -84.792903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224519223, states[0] = 30.856739, states[40]= 0.002343
Saving checkpoint... 
Iteration: 1233961252, states[0] = -84.696678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243456328, states[0] = -84.666317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1253831074, states[0] = -5.841395, states[40]= 0.000224
Saving checkpoint... 
Iteration: 1263971689, states[0] = -84.752438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1277573051, states[0] = 1.690357, states[40]= 0.000147
Saving checkpoint... 
Iteration: 1290403851, states[0] = -83.985272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302437825, states[0] = -84.530169, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314842956, states[0] = -20.364114, states[40]= 0.000157
Saving checkpoint... 
Iteration: 1325311276, states[0] = 10.140606, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1335660276, states[0] = -84.223056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346253567, states[0] = 31.896022, states[40]= 0.655311
Saving checkpoint... 
Iteration: 1356083462, states[0] = -8.538128, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1367313572, states[0] = 8.631183, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1378113942, states[0] = -45.357088, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1389285142, states[0] = 24.785063, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1399255923, states[0] = 29.441761, states[40]= 0.287574
Saving checkpoint... 
Iteration: 1410142907, states[0] = -80.851155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421135375, states[0] = -72.480351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1431988649, states[0] = -84.821923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1443013581, states[0] = 31.252153, states[40]= 0.018049
Saving checkpoint... 
Iteration: 1452997151, states[0] = -84.852536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464728402, states[0] = -84.777310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1476247004, states[0] = -84.851181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1487788491, states[0] = 23.133451, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1499804630, states[0] = 14.268023, states[40]= 0.000021
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.736255
 - CaMKt in component CaMK (millimolar): 0.082493
 - cass in component intracellular_ions (millimolar): 0.000121
 - nai in component intracellular_ions (millimolar): 7.000062
 - nass in component intracellular_ions (millimolar): 7.000265
 - ki in component intracellular_ions (millimolar): 144.476326
 - kss in component intracellular_ions (millimolar): 144.476294
 - cansr in component intracellular_ions (millimolar): 2.467581
 - cajsr in component intracellular_ions (millimolar): 1.895386
 - cai in component intracellular_ions (millimolar): 0.000119
 - m in component INa (dimensionless): 0.010068
 - hf in component INa (dimensionless): 0.579836
 - hs in component INa (dimensionless): 0.579478
 - j in component INa (dimensionless): 0.577208
 - hsp in component INa (dimensionless): 0.331480
 - jp in component INa (dimensionless): 0.573351
 - mL in component INaL (dimensionless): 0.000342
 - hL in component INaL (dimensionless): 0.293557
 - hLp in component INaL (dimensionless): 0.122924
 - a in component Ito (dimensionless): 0.001237
 - iF in component Ito (dimensionless): 0.999226
 - iS in component Ito (dimensionless): 0.253186
 - ap in component Ito (dimensionless): 0.000631
 - iFp in component Ito (dimensionless): 0.999226
 - iSp in component Ito (dimensionless): 0.280121
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.781009
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.981536
 - jca in component ICaL (dimensionless): 0.986171
 - ffp in component ICaL (dimensionless): 0.999999
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.010556
 - xrf in component IKr (dimensionless): 0.007029
 - xrs in component IKr (dimensionless): 0.771560
 - xs1 in component IKs (dimensionless): 0.464853
 - xs2 in component IKs (dimensionless): 0.000352
 - xk1 in component IK1 (dimensionless): 0.996747
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:58:20 (11369): called boinc_finish(0)

</stderr_txt>
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