𝕏

Task 55529095

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_932_0
Workunit 26365608
Created 1 Jul 2024, 14:59:14 UTC
Sent 1 Jul 2024, 18:08:55 UTC
Report deadline 4 Jul 2024, 18:08:55 UTC
Received 1 Jul 2024, 23:50:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 20 min 18 sec
CPU time 2 hours 15 min 36 sec
Validate state Valid
Credit 44.80
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.43 MB
Peak swap size 2.35 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_932.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_932_0_r1483950282_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_932_0_r1483950282_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.312418
     * GNaL_b in INaL: 0.005619
     * Gto_b in Ito: 0.081566
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032121
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.160329
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.269010
     * GKb_b in IKb: 0.003773
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034405
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10828762, states[0] = -94.024896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21655101, states[0] = -93.962582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32503323, states[0] = -93.897281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43327959, states[0] = -93.899498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54134615, states[0] = -19.637246, states[40]= 0.001753
Saving checkpoint... 
Iteration: 64973739, states[0] = -93.874499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75841653, states[0] = -93.903938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86626841, states[0] = -93.864862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97448464, states[0] = -93.882155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108268084, states[0] = -93.455144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119119979, states[0] = -93.868843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129835229, states[0] = -93.902092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140702497, states[0] = -93.863002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151542743, states[0] = -93.878837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162362170, states[0] = -93.726981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173201020, states[0] = -93.867387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184020185, states[0] = -93.895781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194856130, states[0] = -93.861694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205689801, states[0] = -93.875279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216531208, states[0] = -93.873509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227347131, states[0] = -93.865632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238175688, states[0] = -93.889732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249038951, states[0] = 28.278685, states[40]= 0.000179
Saving checkpoint... 
Iteration: 259878225, states[0] = -93.871659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270735881, states[0] = -93.901777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281436142, states[0] = -93.864669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292279543, states[0] = -93.886001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303105115, states[0] = 2.079128, states[40]= 0.003547
Saving checkpoint... 
Iteration: 313951067, states[0] = -93.870401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324481967, states[0] = -93.851371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335315503, states[0] = -93.865755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346172456, states[0] = -93.889657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357043711, states[0] = 26.879304, states[40]= 0.000232
Saving checkpoint... 
Iteration: 367871183, states[0] = -93.871592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378707290, states[0] = -93.900760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389542285, states[0] = -93.863562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400371093, states[0] = -93.882922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411174384, states[0] = -49.590342, states[40]= 0.000249
Saving checkpoint... 
Iteration: 421813169, states[0] = -93.872508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432627277, states[0] = -93.894445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443474673, states[0] = -93.864053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454321288, states[0] = -93.884376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465163489, states[0] = -41.122096, states[40]= 0.000779
Saving checkpoint... 
Iteration: 475958595, states[0] = -93.870021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486794746, states[0] = -93.901720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497634279, states[0] = -93.862658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508450803, states[0] = -93.880454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519269443, states[0] = -93.459555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530091776, states[0] = -93.868051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540949551, states[0] = -93.897749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551765562, states[0] = -93.861635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562621133, states[0] = -93.876133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573419986, states[0] = -93.803878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584488808, states[0] = -93.863699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595474848, states[0] = -93.879662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606445432, states[0] = -93.826537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617420111, states[0] = -93.864266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628374305, states[0] = -93.882455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639346125, states[0] = -93.695494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650335685, states[0] = -93.865035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661320518, states[0] = -93.884064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672327987, states[0] = -93.654490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683320922, states[0] = -93.865132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694062145, states[0] = -93.893261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705046697, states[0] = 25.944994, states[40]= 0.000276
Saving checkpoint... 
Iteration: 715892946, states[0] = -93.870665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726677562, states[0] = -93.898663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737521527, states[0] = -93.863170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748400809, states[0] = -93.881477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759276462, states[0] = -93.488555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770080065, states[0] = -93.867816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780967991, states[0] = -93.896695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791847847, states[0] = -93.860714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802702741, states[0] = -93.873999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813552620, states[0] = -93.879225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824448219, states[0] = -93.863670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835326704, states[0] = -93.883586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846188213, states[0] = -60.482600, states[40]= 0.000045
Saving checkpoint... 
Iteration: 857081036, states[0] = -93.867662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867841340, states[0] = -93.900423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878625804, states[0] = -93.862103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889453466, states[0] = -93.879763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900322423, states[0] = -93.639991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911151023, states[0] = -93.866679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921966124, states[0] = -93.896535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932820203, states[0] = -93.860658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943689643, states[0] = -93.874039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954549542, states[0] = -93.878116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965339533, states[0] = -93.864484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976236608, states[0] = -93.886345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987098599, states[0] = 5.479386, states[40]= 0.003131
Saving checkpoint... 
Iteration: 997963480, states[0] = -93.869099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008809967, states[0] = -93.900723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019551794, states[0] = -93.862460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030417181, states[0] = -93.880548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041296455, states[0] = -93.562407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052068886, states[0] = -93.867507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062913383, states[0] = -93.898137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073643183, states[0] = -93.861654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084488852, states[0] = -93.878498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095354916, states[0] = -93.712088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105982780, states[0] = -93.868635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116819635, states[0] = -93.900414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127667898, states[0] = -93.861383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138519908, states[0] = -93.877610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149392885, states[0] = -93.771850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160103492, states[0] = -93.866875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170962650, states[0] = -93.896258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181800967, states[0] = -93.860377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192685955, states[0] = -93.873711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203534197, states[0] = -93.872901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214339998, states[0] = -93.864074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225315390, states[0] = -93.883313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236476569, states[0] = -93.846796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247716828, states[0] = -93.860837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258924080, states[0] = -93.869283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270117182, states[0] = -93.890220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281322894, states[0] = -93.640591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292514008, states[0] = -93.862331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303701737, states[0] = -93.873206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314557463, states[0] = -93.879744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325715430, states[0] = -93.860720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336923268, states[0] = -93.869169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348141266, states[0] = -93.889187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359353364, states[0] = -93.708703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370494014, states[0] = -93.862377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381697458, states[0] = -93.873167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392875506, states[0] = -93.898742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404018839, states[0] = 31.931597, states[40]= 0.002774
Saving checkpoint... 
Iteration: 1415140409, states[0] = -93.865991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426217933, states[0] = -93.886269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437411859, states[0] = -93.793980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448607314, states[0] = -93.861319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459766598, states[0] = -93.871679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470845415, states[0] = -93.899360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482093452, states[0] = 7.941784, states[40]= 0.002707
Saving checkpoint... 
Iteration: 1493415011, states[0] = -93.862890, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.734658
 - CaMKt in component CaMK (millimolar): 0.001310
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.709278
 - nass in component intracellular_ions (millimolar): 6.709402
 - ki in component intracellular_ions (millimolar): 145.155708
 - kss in component intracellular_ions (millimolar): 145.155699
 - cansr in component intracellular_ions (millimolar): 1.829252
 - cajsr in component intracellular_ions (millimolar): 1.829125
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004071
 - hf in component INa (dimensionless): 0.858226
 - hs in component INa (dimensionless): 0.858227
 - j in component INa (dimensionless): 0.858228
 - hsp in component INa (dimensionless): 0.686092
 - jp in component INa (dimensionless): 0.858229
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.697321
 - hLp in component INaL (dimensionless): 0.501677
 - a in component Ito (dimensionless): 0.000675
 - iF in component Ito (dimensionless): 0.999840
 - iS in component Ito (dimensionless): 0.999222
 - ap in component Ito (dimensionless): 0.000344
 - iFp in component Ito (dimensionless): 0.999840
 - iSp in component Ito (dimensionless): 0.999696
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999522
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005438
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000594
 - xs1 in component IKs (dimensionless): 0.014700
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997627
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:45:25 (3735): called boinc_finish(0)

</stderr_txt>
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