𝕏

Task 55528988

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_10000-conf_532_1
Workunit 26365554
Created 1 Jul 2024, 14:59:14 UTC
Sent 1 Jul 2024, 18:08:55 UTC
Report deadline 4 Jul 2024, 18:08:55 UTC
Received 1 Jul 2024, 21:29:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 20 min 48 sec
CPU time 2 hours 15 min 53 sec
Validate state Valid
Credit 44.11
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.41 MB
Peak swap size 2.35 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_10000-conf_532.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_10000-conf_532_1_r852606364_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_10000-conf_532_1_r852606364_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.784404
     * GNaL_b in INaL: 0.005847
     * Gto_b in Ito: 0.081973
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032240
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.163809
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.561647
     * GKb_b in IKb: 0.003831
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030941
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11193467, states[0] = -94.014934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22369038, states[0] = -93.913922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33384912, states[0] = -93.867505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44570956, states[0] = -93.845133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55770080, states[0] = -93.878973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66962657, states[0] = -93.844604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78126770, states[0] = -93.832983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89291187, states[0] = -93.828620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100438584, states[0] = -93.789397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111635850, states[0] = -93.846215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122819905, states[0] = -93.832200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134019051, states[0] = -93.827733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145039980, states[0] = 28.179232, states[40]= 0.000170
Saving checkpoint... 
Iteration: 156240585, states[0] = -93.856336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167432852, states[0] = -93.834526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178609147, states[0] = -93.828427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189716327, states[0] = -93.826187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200861340, states[0] = -93.869334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212047005, states[0] = -93.838493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223219380, states[0] = -93.829639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234412369, states[0] = -93.826536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245599344, states[0] = -93.858333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256773437, states[0] = -93.842625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267973413, states[0] = -93.830684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279180853, states[0] = -93.826879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290311653, states[0] = -93.574997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301384044, states[0] = -93.851512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312540283, states[0] = -93.833352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323654150, states[0] = -93.828041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334637366, states[0] = -93.826069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345822197, states[0] = -93.869891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356994103, states[0] = -93.839016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368201256, states[0] = -93.829533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379377852, states[0] = -93.826422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390559406, states[0] = -93.849394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401709612, states[0] = -93.843658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412879005, states[0] = -93.831027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424051962, states[0] = -93.826981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435236702, states[0] = -93.235463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446419761, states[0] = -93.850355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457429319, states[0] = -93.834111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468605652, states[0] = -93.828031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479810379, states[0] = -93.825686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490995857, states[0] = -93.864687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502133612, states[0] = -93.837074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513328601, states[0] = -93.828892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524507942, states[0] = -93.826067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535687334, states[0] = -93.867715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546875655, states[0] = -93.840588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558063207, states[0] = -93.829945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569233308, states[0] = -93.826482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580249843, states[0] = -93.330651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590950139, states[0] = -93.866219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601552336, states[0] = -93.846820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612315685, states[0] = -93.835000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623112764, states[0] = -93.829654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633234673, states[0] = -93.829130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643571016, states[0] = -93.827957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654309055, states[0] = -93.826261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665094149, states[0] = 7.941295, states[40]= 0.002681
Saving checkpoint... 
Iteration: 675861519, states[0] = -93.868792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686621988, states[0] = -93.845165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697398398, states[0] = -93.834141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708168850, states[0] = -93.829325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718742359, states[0] = -93.827403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729529875, states[0] = -93.825827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740269976, states[0] = -93.423946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750866250, states[0] = -93.868602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761591870, states[0] = -93.845752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772302930, states[0] = -93.834964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783014037, states[0] = -93.829953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793685175, states[0] = -93.827480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804359259, states[0] = -93.826024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815070287, states[0] = 17.840064, states[40]= 0.000952
Saving checkpoint... 
Iteration: 825780571, states[0] = -93.869742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836425819, states[0] = -93.849797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847131214, states[0] = -93.836755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857846713, states[0] = -93.830760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868570147, states[0] = -93.827733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879302384, states[0] = -93.826046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890015374, states[0] = 31.931995, states[40]= 0.009210
Saving checkpoint... 
Iteration: 900608419, states[0] = -93.859185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911279216, states[0] = -93.854096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921969276, states[0] = -93.838796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932684685, states[0] = -93.831686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943354979, states[0] = -93.828363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954012100, states[0] = -93.826530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964689290, states[0] = -93.825359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975396210, states[0] = -93.742775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986100412, states[0] = -93.860288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996823608, states[0] = -93.840990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007495840, states[0] = -93.833000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018228289, states[0] = -93.828768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028953128, states[0] = -93.826583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039565155, states[0] = -93.825462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050257596, states[0] = -93.367777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060965269, states[0] = -93.865218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071691774, states[0] = -93.843333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082260233, states[0] = -93.835084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092944487, states[0] = -93.829990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103669888, states[0] = -93.827209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114356784, states[0] = -93.825716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125054613, states[0] = 23.531591, states[40]= 0.000399
Saving checkpoint... 
Iteration: 1135788413, states[0] = -93.869414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146480374, states[0] = -93.848038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157212677, states[0] = -93.835514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167941033, states[0] = -93.829933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178679252, states[0] = -93.827108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189271945, states[0] = -93.825787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200000979, states[0] = 47.311685, states[40]= 0.296809
Saving checkpoint... 
Iteration: 1210713838, states[0] = -93.868277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221475285, states[0] = -93.848094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232189536, states[0] = -93.835694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242839980, states[0] = -93.830411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253516084, states[0] = -93.827510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264251268, states[0] = -93.825749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274909132, states[0] = -93.824759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285541230, states[0] = -93.843157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296210776, states[0] = -93.856000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306945407, states[0] = -93.838755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317664438, states[0] = -93.831435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328367673, states[0] = -93.827929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338962632, states[0] = -93.826249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349705472, states[0] = -93.824949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360392116, states[0] = -93.737040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371147440, states[0] = -93.858171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381814699, states[0] = -93.840754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392481728, states[0] = -93.832727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403226238, states[0] = -93.828388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413942952, states[0] = -93.826217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424681480, states[0] = -93.824906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435404217, states[0] = -93.752176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446166385, states[0] = -93.857412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456768266, states[0] = -93.841496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467477616, states[0] = -93.832685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478079638, states[0] = -93.828942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488787625, states[0] = -93.826511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499760736, states[0] = -93.824723, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.700410
 - CaMKt in component CaMK (millimolar): 0.001027
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 6.676275
 - nass in component intracellular_ions (millimolar): 6.676401
 - ki in component intracellular_ions (millimolar): 145.190312
 - kss in component intracellular_ions (millimolar): 145.190303
 - cansr in component intracellular_ions (millimolar): 1.844221
 - cajsr in component intracellular_ions (millimolar): 1.844132
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.004085
 - hf in component INa (dimensionless): 0.857540
 - hs in component INa (dimensionless): 0.857540
 - j in component INa (dimensionless): 0.857541
 - hsp in component INa (dimensionless): 0.684877
 - jp in component INa (dimensionless): 0.857541
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.696341
 - hLp in component INaL (dimensionless): 0.500496
 - a in component Ito (dimensionless): 0.000676
 - iF in component Ito (dimensionless): 0.999839
 - iS in component Ito (dimensionless): 0.999836
 - ap in component Ito (dimensionless): 0.000344
 - iFp in component Ito (dimensionless): 0.999839
 - iSp in component Ito (dimensionless): 0.999839
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999991
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005690
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002149
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997635
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:25:05 (2587): called boinc_finish(0)

</stderr_txt>
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