𝕏

Task 55528954

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_5000-conf_832_1
Workunit 26365537
Created 1 Jul 2024, 14:59:14 UTC
Sent 1 Jul 2024, 18:08:55 UTC
Report deadline 4 Jul 2024, 18:08:55 UTC
Received 1 Jul 2024, 23:50:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 20 min 44 sec
CPU time 2 hours 15 min 59 sec
Validate state Valid
Credit 44.32
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.20 MB
Peak swap size 2.35 GB
Peak disk usage 1.56 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_5000-conf_832.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_5000-conf_832_1_r1129284939_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Coppini_5000-conf_832_1_r1129284939_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.257737
     * GNaL_b in INaL: 0.005850
     * Gto_b in Ito: 0.082766
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032129
     * GKs_b in IKs: 0.001938
     * GK1_b in IK1: 0.163176
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.960664
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029462
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10936828, states[0] = -94.664654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21738328, states[0] = -94.583560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32545998, states[0] = 21.150750, states[40]= 0.002676
Saving checkpoint... 
Iteration: 43336729, states[0] = -94.529575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54165962, states[0] = -94.500754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64972426, states[0] = -94.483931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75741607, states[0] = -94.495505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86539636, states[0] = -94.479121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97277704, states[0] = -94.468440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108038745, states[0] = -94.463852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118833807, states[0] = -94.473482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129649701, states[0] = -94.462560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140366446, states[0] = -94.364676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151175272, states[0] = -94.472649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161988535, states[0] = -94.460824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172814213, states[0] = -94.288521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183604289, states[0] = -94.472371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194410302, states[0] = -94.460160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205218589, states[0] = -93.996113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216020253, states[0] = -94.473290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226840498, states[0] = -94.460197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237642034, states[0] = -31.645039, states[40]= 0.001152
Saving checkpoint... 
Iteration: 248445255, states[0] = -94.474306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259233236, states[0] = -94.461018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270071770, states[0] = 13.681462, states[40]= 0.004074
Saving checkpoint... 
Iteration: 280884719, states[0] = -94.474991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291613569, states[0] = -94.462296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302403640, states[0] = -94.455684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313215400, states[0] = -94.473880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324020663, states[0] = -94.463473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334545090, states[0] = -94.457899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345341394, states[0] = -94.329654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356138442, states[0] = -94.470169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366907748, states[0] = -94.458999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377720988, states[0] = -94.013783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388540882, states[0] = -94.472136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399333651, states[0] = -94.459663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410134298, states[0] = -25.471252, states[40]= 0.001565
Saving checkpoint... 
Iteration: 420880087, states[0] = -94.474821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431489365, states[0] = -94.463813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442321514, states[0] = -94.455962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453109542, states[0] = -94.466409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463908896, states[0] = -94.465039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474715757, states[0] = -94.456575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485491207, states[0] = -94.441121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496285779, states[0] = -94.467159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507093557, states[0] = -94.457384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517914096, states[0] = -94.402253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528692109, states[0] = -94.468943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539464264, states[0] = -94.458374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550258622, states[0] = -94.153280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561051385, states[0] = -94.471796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571849781, states[0] = -94.459381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582615858, states[0] = -10.499171, states[40]= 0.002420
Saving checkpoint... 
Iteration: 593637686, states[0] = -94.470001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604578364, states[0] = -94.457428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615512461, states[0] = -94.447785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626469793, states[0] = -94.463969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637393891, states[0] = -94.455428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648307982, states[0] = -94.475040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659251734, states[0] = -94.460321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670213775, states[0] = -93.913992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681146614, states[0] = -94.469759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692066882, states[0] = -94.457454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702825291, states[0] = -94.305243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713782673, states[0] = -94.467067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724574695, states[0] = -94.457373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735365855, states[0] = -94.359551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746175848, states[0] = -94.469120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757018965, states[0] = -94.457778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767867621, states[0] = -94.361448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778628520, states[0] = -94.470063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789464819, states[0] = -94.458198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800284442, states[0] = -94.223768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811128705, states[0] = -94.470037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821934333, states[0] = -94.458436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832794607, states[0] = -94.247151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843654761, states[0] = -94.469481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854487454, states[0] = -94.457965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865335366, states[0] = -94.320672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876032568, states[0] = -94.471960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886769832, states[0] = -94.459972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897587102, states[0] = 7.184396, states[40]= 0.004623
Saving checkpoint... 
Iteration: 908421653, states[0] = -94.473942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919253191, states[0] = -94.460127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930052980, states[0] = 20.071887, states[40]= 0.002956
Saving checkpoint... 
Iteration: 940881686, states[0] = -94.474444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951723002, states[0] = -94.460436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962521436, states[0] = 26.994513, states[40]= 0.002632
Saving checkpoint... 
Iteration: 973298523, states[0] = -94.474793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984114572, states[0] = -94.461709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994948880, states[0] = -94.454901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005756618, states[0] = -94.474361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016595685, states[0] = -94.461930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027322620, states[0] = -94.455552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038140475, states[0] = -94.469088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048987500, states[0] = -94.463414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059780679, states[0] = -94.455774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070601006, states[0] = -94.464951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081305488, states[0] = -94.466396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092127996, states[0] = -94.456737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102941942, states[0] = -94.419068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113558022, states[0] = -94.471283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124371574, states[0] = -94.458796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135190984, states[0] = -78.342931, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146010265, states[0] = -94.472217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156819573, states[0] = -94.459276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167563921, states[0] = 16.545957, states[40]= 0.003637
Saving checkpoint... 
Iteration: 1178394976, states[0] = -94.474125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189209199, states[0] = -94.460429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199998007, states[0] = -94.454521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210850710, states[0] = -94.474536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221647925, states[0] = -94.461130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232635592, states[0] = -26.493816, states[40]= 0.001543
Saving checkpoint... 
Iteration: 1243773784, states[0] = -94.466870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255009538, states[0] = 26.747160, states[40]= 0.055924
Saving checkpoint... 
Iteration: 1266154664, states[0] = -94.469194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277295615, states[0] = -94.455537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288447299, states[0] = -94.473274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299621150, states[0] = -94.456643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310775247, states[0] = -94.474400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321584799, states[0] = -94.461864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332730600, states[0] = -94.057500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343865803, states[0] = -94.465154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355031725, states[0] = 25.528148, states[40]= 0.001950
Saving checkpoint... 
Iteration: 1366169896, states[0] = -94.468816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377271578, states[0] = -94.455610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388449096, states[0] = -94.473175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399602543, states[0] = -94.456707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410649843, states[0] = -94.469586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421843867, states[0] = -94.458856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432942072, states[0] = -94.418912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444127308, states[0] = -94.461233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455292777, states[0] = -94.242676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466375871, states[0] = -94.464899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477502306, states[0] = 41.871646, states[40]= 0.421786
Saving checkpoint... 
Iteration: 1488724796, states[0] = -94.467640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499935933, states[0] = -94.454620, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.330281
 - CaMKt in component CaMK (millimolar): 0.001123
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.297916
 - nass in component intracellular_ions (millimolar): 6.298002
 - ki in component intracellular_ions (millimolar): 145.627583
 - kss in component intracellular_ions (millimolar): 145.627572
 - cansr in component intracellular_ions (millimolar): 1.566010
 - cajsr in component intracellular_ions (millimolar): 1.566041
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003833
 - hf in component INa (dimensionless): 0.869722
 - hs in component INa (dimensionless): 0.869723
 - j in component INa (dimensionless): 0.869724
 - hsp in component INa (dimensionless): 0.706777
 - jp in component INa (dimensionless): 0.869724
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.713840
 - hLp in component INaL (dimensionless): 0.521446
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997761
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999258
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998875
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002993
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001786
 - xs1 in component IKs (dimensionless): 0.022612
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997483
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:44:53 (3717): called boinc_finish(0)

</stderr_txt>
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