𝕏

Task 55528501

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_31_0
Workunit 26365311
Created 1 Jul 2024, 14:58:58 UTC
Sent 1 Jul 2024, 18:08:55 UTC
Report deadline 4 Jul 2024, 18:08:55 UTC
Received 2 Jul 2024, 2:08:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 18 min 12 sec
CPU time 2 hours 13 min 29 sec
Validate state Valid
Credit 44.17
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.48 MB
Peak swap size 2.35 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_31.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_31_0_r358391749_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_333-conf_31_0_r358391749_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.428817
     * GNaL_b in INaL: 0.006065
     * Gto_b in Ito: 0.084906
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032381
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.167702
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.820132
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033854
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11199192, states[0] = 22.566147, states[40]= 0.000151
Saving checkpoint... 
Iteration: 22297861, states[0] = -84.073723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33303484, states[0] = -84.640989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 44457587, states[0] = -83.131961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 55624560, states[0] = -83.779272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66771335, states[0] = -62.879719, states[40]= 0.000024
Saving checkpoint... 
Iteration: 77952809, states[0] = -83.081416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89105222, states[0] = -67.816492, states[40]= 0.000013
Saving checkpoint... 
Iteration: 100254156, states[0] = -44.499118, states[40]= 0.000141
Saving checkpoint... 
Iteration: 111404444, states[0] = -23.602487, states[40]= 0.000259
Saving checkpoint... 
Iteration: 122563824, states[0] = -14.611092, states[40]= 0.000287
Saving checkpoint... 
Iteration: 133524459, states[0] = 20.264401, states[40]= 0.000005
Saving checkpoint... 
Iteration: 144635857, states[0] = -84.903344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155751239, states[0] = -48.276358, states[40]= 0.000100
Saving checkpoint... 
Iteration: 166638446, states[0] = -84.960760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177740768, states[0] = -37.153553, states[40]= 0.000221
Saving checkpoint... 
Iteration: 188854210, states[0] = 19.088802, states[40]= 0.000005
Saving checkpoint... 
Iteration: 199914372, states[0] = -49.486849, states[40]= 0.000089
Saving checkpoint... 
Iteration: 211025984, states[0] = 14.429623, states[40]= 0.000015
Saving checkpoint... 
Iteration: 222130832, states[0] = -84.933445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 233260021, states[0] = -72.355001, states[40]= 0.000007
Saving checkpoint... 
Iteration: 244364229, states[0] = 8.479522, states[40]= 0.000062
Saving checkpoint... 
Iteration: 255513392, states[0] = 19.579051, states[40]= 0.000005
Saving checkpoint... 
Iteration: 266617570, states[0] = -84.810572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277545477, states[0] = -10.529246, states[40]= 0.000317
Saving checkpoint... 
Iteration: 288671068, states[0] = 22.818692, states[40]= 0.000015
Saving checkpoint... 
Iteration: 299373985, states[0] = -6.837529, states[40]= 0.000319
Saving checkpoint... 
Iteration: 310248428, states[0] = -66.226638, states[40]= 0.000015
Saving checkpoint... 
Iteration: 321366261, states[0] = -0.246168, states[40]= 0.000227
Saving checkpoint... 
Iteration: 332497232, states[0] = 24.289538, states[40]= 0.000040
Saving checkpoint... 
Iteration: 343578568, states[0] = -66.440977, states[40]= 0.000014
Saving checkpoint... 
Iteration: 354722959, states[0] = -37.005027, states[40]= 0.000222
Saving checkpoint... 
Iteration: 365841238, states[0] = 16.141664, states[40]= 0.000010
Saving checkpoint... 
Iteration: 377048038, states[0] = -28.704096, states[40]= 0.000267
Saving checkpoint... 
Iteration: 388169718, states[0] = 17.801525, states[40]= 0.000006
Saving checkpoint... 
Iteration: 399293775, states[0] = -37.542619, states[40]= 0.000029
Saving checkpoint... 
Iteration: 410393679, states[0] = -49.955032, states[40]= 0.000085
Saving checkpoint... 
Iteration: 421539599, states[0] = -23.031022, states[40]= 0.000251
Saving checkpoint... 
Iteration: 432475499, states[0] = 28.970960, states[40]= 0.002654
Saving checkpoint... 
Iteration: 443590400, states[0] = -84.525119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 454727140, states[0] = -56.195452, states[40]= 0.000046
Saving checkpoint... 
Iteration: 465873772, states[0] = -30.489235, states[40]= 0.000266
Saving checkpoint... 
Iteration: 477006610, states[0] = 9.273645, states[40]= 0.000053
Saving checkpoint... 
Iteration: 488109289, states[0] = -84.974966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 499167447, states[0] = 11.938123, states[40]= 0.000029
Saving checkpoint... 
Iteration: 510279289, states[0] = -85.031325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 521379659, states[0] = -46.012484, states[40]= 0.000121
Saving checkpoint... 
Iteration: 532496320, states[0] = 12.733492, states[40]= 0.000024
Saving checkpoint... 
Iteration: 543580195, states[0] = -84.506060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554671494, states[0] = 4.367676, states[40]= 0.000127
Saving checkpoint... 
Iteration: 565791269, states[0] = 29.485289, states[40]= 0.012563
Saving checkpoint... 
Iteration: 576889347, states[0] = -67.614151, states[40]= 0.000012
Saving checkpoint... 
Iteration: 587805861, states[0] = 23.866587, states[40]= 0.000030
Saving checkpoint... 
Iteration: 598903506, states[0] = -84.003082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610015972, states[0] = -16.016281, states[40]= 0.000271
Saving checkpoint... 
Iteration: 621111926, states[0] = 28.191530, states[40]= 0.177490
Saving checkpoint... 
Iteration: 632173852, states[0] = -6.572170, states[40]= 0.000317
Saving checkpoint... 
Iteration: 643272699, states[0] = 30.693902, states[40]= 0.655502
Saving checkpoint... 
Iteration: 654356922, states[0] = -33.239216, states[40]= 0.000254
Saving checkpoint... 
Iteration: 665442700, states[0] = 28.663543, states[40]= 0.089097
Saving checkpoint... 
Iteration: 676393725, states[0] = -83.503312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 687506442, states[0] = -13.366955, states[40]= 0.000293
Saving checkpoint... 
Iteration: 698564821, states[0] = -84.502895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 709692166, states[0] = -43.320837, states[40]= 0.000149
Saving checkpoint... 
Iteration: 720763076, states[0] = 35.162343, states[40]= 1.194096
Saving checkpoint... 
Iteration: 731871325, states[0] = -63.720894, states[40]= 0.000020
Saving checkpoint... 
Iteration: 742846255, states[0] = -30.721208, states[40]= 0.000265
Saving checkpoint... 
Iteration: 753938234, states[0] = 29.467923, states[40]= 0.017435
Saving checkpoint... 
Iteration: 765050419, states[0] = -83.099612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776131451, states[0] = 17.479047, states[40]= 0.000007
Saving checkpoint... 
Iteration: 787199938, states[0] = -64.943382, states[40]= 0.000017
Saving checkpoint... 
Iteration: 798241641, states[0] = -84.918659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809354658, states[0] = -51.105351, states[40]= 0.000076
Saving checkpoint... 
Iteration: 820462998, states[0] = 15.790829, states[40]= 0.000011
Saving checkpoint... 
Iteration: 831565780, states[0] = -84.843990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842694474, states[0] = -65.066437, states[40]= 0.000017
Saving checkpoint... 
Iteration: 853748494, states[0] = 23.585511, states[40]= 0.028778
Saving checkpoint... 
Iteration: 864861393, states[0] = -68.895831, states[40]= 0.000011
Saving checkpoint... 
Iteration: 875973565, states[0] = 3.594054, states[40]= 0.000143
Saving checkpoint... 
Iteration: 887082487, states[0] = 29.179269, states[40]= 0.489507
Saving checkpoint... 
Iteration: 898058260, states[0] = -84.828119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909145984, states[0] = -6.331397, states[40]= 0.000317
Saving checkpoint... 
Iteration: 920234209, states[0] = -84.964172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931305816, states[0] = -0.805282, states[40]= 0.000237
Saving checkpoint... 
Iteration: 942343556, states[0] = -54.089406, states[40]= 0.000057
Saving checkpoint... 
Iteration: 953483461, states[0] = -18.704170, states[40]= 0.000253
Saving checkpoint... 
Iteration: 964572865, states[0] = 33.406467, states[40]= 0.934784
Saving checkpoint... 
Iteration: 975666106, states[0] = -44.020983, states[40]= 0.000141
Saving checkpoint... 
Iteration: 986741233, states[0] = 28.113767, states[40]= 0.236505
Saving checkpoint... 
Iteration: 997869943, states[0] = -84.569650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008965700, states[0] = -1.885789, states[40]= 0.000259
Saving checkpoint... 
Iteration: 1020070163, states[0] = 28.336741, states[40]= 0.346861
Saving checkpoint... 
Iteration: 1031146914, states[0] = -25.296198, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1042049694, states[0] = -84.893053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1053111376, states[0] = 12.426040, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1063996490, states[0] = -51.949332, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1075102192, states[0] = 17.083902, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1086174213, states[0] = -71.420692, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1097223876, states[0] = -50.958478, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1108315372, states[0] = -38.447038, states[40]= 0.000205
Saving checkpoint... 
Iteration: 1119369702, states[0] = -84.818036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1130463613, states[0] = -15.509394, states[40]= 0.000272
Saving checkpoint... 
Iteration: 1141458303, states[0] = -9.360137, states[40]= 0.000321
Saving checkpoint... 
Iteration: 1152508749, states[0] = -81.365940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1163632043, states[0] = -22.963616, states[40]= 0.000250
Saving checkpoint... 
Iteration: 1174670378, states[0] = -78.589657, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1185731694, states[0] = 29.318999, states[40]= 0.005133
Saving checkpoint... 
Iteration: 1196653055, states[0] = -56.272070, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1207704973, states[0] = -84.941442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218785170, states[0] = -11.163861, states[40]= 0.000309
Saving checkpoint... 
Iteration: 1229852661, states[0] = -84.717577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240892503, states[0] = 29.363669, states[40]= 0.005818
Saving checkpoint... 
Iteration: 1251976274, states[0] = -50.001460, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1263097462, states[0] = 7.088615, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1274180141, states[0] = -84.685860, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285232709, states[0] = 25.586633, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1296308473, states[0] = -54.484390, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1307302452, states[0] = -47.818933, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1318387776, states[0] = 28.773994, states[40]= 0.001926
Saving checkpoint... 
Iteration: 1329449559, states[0] = -24.051088, states[40]= 0.000253
Saving checkpoint... 
Iteration: 1340531586, states[0] = -84.999715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351448810, states[0] = -26.123995, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1362517692, states[0] = -84.873746, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1373575247, states[0] = 15.215986, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1384650909, states[0] = -80.212077, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1395759152, states[0] = -0.553448, states[40]= 0.000232
Saving checkpoint... 
Iteration: 1406834477, states[0] = -84.696771, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1417923718, states[0] = -0.676278, states[40]= 0.000234
Saving checkpoint... 
Iteration: 1428976394, states[0] = -76.083945, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1439855202, states[0] = -84.995712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450934910, states[0] = -20.423883, states[40]= 0.000248
Saving checkpoint... 
Iteration: 1462050789, states[0] = 24.390854, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1473153758, states[0] = -84.432395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484238459, states[0] = 9.873539, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1495350252, states[0] = -84.998002, states[40]= 0.000001
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.875221
 - CaMKt in component CaMK (millimolar): 0.217210
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.280109
 - nass in component intracellular_ions (millimolar): 7.280463
 - ki in component intracellular_ions (millimolar): 143.836540
 - kss in component intracellular_ions (millimolar): 143.836504
 - cansr in component intracellular_ions (millimolar): 3.339634
 - cajsr in component intracellular_ions (millimolar): 1.928005
 - cai in component intracellular_ions (millimolar): 0.000162
 - m in component INa (dimensionless): 0.009929
 - hf in component INa (dimensionless): 0.585380
 - hs in component INa (dimensionless): 0.584360
 - j in component INa (dimensionless): 0.556672
 - hsp in component INa (dimensionless): 0.333066
 - jp in component INa (dimensionless): 0.516310
 - mL in component INaL (dimensionless): 0.000333
 - hL in component INaL (dimensionless): 0.186914
 - hLp in component INaL (dimensionless): 0.076587
 - a in component Ito (dimensionless): 0.001226
 - iF in component Ito (dimensionless): 0.999241
 - iS in component Ito (dimensionless): 0.132708
 - ap in component Ito (dimensionless): 0.000625
 - iFp in component Ito (dimensionless): 0.999242
 - iSp in component Ito (dimensionless): 0.148695
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.679039
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.929607
 - jca in component ICaL (dimensionless): 0.912317
 - ffp in component ICaL (dimensionless): 0.999010
 - fcafp in component ICaL (dimensionless): 0.999942
 - nca in component ICaL (dimensionless): 0.042067
 - xrf in component IKr (dimensionless): 0.097138
 - xrs in component IKr (dimensionless): 0.871065
 - xs1 in component IKs (dimensionless): 0.569398
 - xs2 in component IKs (dimensionless): 0.006772
 - xk1 in component IK1 (dimensionless): 0.996728
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:03:07 (4852): called boinc_finish(0)

</stderr_txt>
]]>


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