𝕏

Task 55528365

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_431_0
Workunit 26365243
Created 1 Jul 2024, 14:58:58 UTC
Sent 1 Jul 2024, 18:09:35 UTC
Report deadline 4 Jul 2024, 18:09:35 UTC
Received 5 Jul 2024, 12:37:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228543
Run time 1 hours 47 min 58 sec
CPU time 28 min 35 sec
Validate state Valid
Credit 43.05
Device peak FLOPS 5.62 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.39 MB
Peak swap size 391.75 GB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>7.20.7</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_431.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_431_0_r42912707_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_4000-conf_431_0_r42912707_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.681262
     * GNaL_b in INaL: 0.005827
     * Gto_b in Ito: 0.084004
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032158
     * GKs_b in IKs: 0.001917
     * GK1_b in IK1: 0.166851
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.940255
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037346
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12646454, states[0] = -86.776777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20496819, states[0] = -86.710222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32194627, states[0] = -86.339385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40147894, states[0] = -46.176661, states[40]= 0.000049
Saving checkpoint... 
Iteration: 51905921, states[0] = -86.602785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61794932, states[0] = -86.585756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74396957, states[0] = -86.538857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82741118, states[0] = -86.574354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93983677, states[0] = -86.551338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104379139, states[0] = -86.508709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116171479, states[0] = -64.706677, states[40]= 0.000002
Saving checkpoint... 
Iteration: 123627285, states[0] = -86.540599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137808686, states[0] = -86.535341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147231414, states[0] = -86.540345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156318196, states[0] = -86.453510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165279051, states[0] = -86.537080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177279114, states[0] = -86.535933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187351669, states[0] = -86.534091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196244259, states[0] = -86.359098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206472860, states[0] = -86.522493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221220629, states[0] = -86.534661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229958649, states[0] = -86.526341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238581132, states[0] = -86.536132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246456250, states[0] = -86.517638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260156514, states[0] = -48.764647, states[40]= 0.000032
Saving checkpoint... 
Iteration: 275373579, states[0] = -86.531402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287724797, states[0] = -86.527344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298654967, states[0] = -86.539308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308145978, states[0] = -39.323002, states[40]= 0.000141
Saving checkpoint... 
Iteration: 319597971, states[0] = -86.528424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337124090, states[0] = -86.535233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349718252, states[0] = -86.527203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367351668, states[0] = -86.531412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383968522, states[0] = -86.525306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396575801, states[0] = -86.534942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408998187, states[0] = -86.537498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417724843, states[0] = -86.527088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426597334, states[0] = -86.536460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434791520, states[0] = -86.540413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445623132, states[0] = -86.528035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456324668, states[0] = -86.453508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466448251, states[0] = -86.514907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485229884, states[0] = -86.533272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499520741, states[0] = -86.529134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512792149, states[0] = -86.540389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522585424, states[0] = -86.535631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534459241, states[0] = -86.517689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541551093, states[0] = -86.528779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552014989, states[0] = 21.963537, states[40]= 0.015497
Saving checkpoint... 
Iteration: 560722659, states[0] = -86.540336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570451117, states[0] = -86.515641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578501279, states[0] = -86.526123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590782917, states[0] = -86.540418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602026765, states[0] = 21.129239, states[40]= 0.005484
Saving checkpoint... 
Iteration: 612131854, states[0] = -27.237756, states[40]= 0.000632
Saving checkpoint... 
Iteration: 623245424, states[0] = -86.532985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632407882, states[0] = -86.501826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642196150, states[0] = -85.854101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651238305, states[0] = -86.533098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660753189, states[0] = -86.540453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671241883, states[0] = -86.533035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679756110, states[0] = -86.526761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688016937, states[0] = 21.948755, states[40]= 0.011374
Saving checkpoint... 
Iteration: 700646911, states[0] = -86.538786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713207262, states[0] = -86.533612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729060087, states[0] = -86.536273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746791385, states[0] = -86.540349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763368027, states[0] = -86.531066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779711837, states[0] = -86.527125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795687565, states[0] = -86.527342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809865705, states[0] = -86.525888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827582631, states[0] = -86.528380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845997216, states[0] = -86.525021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862925163, states[0] = -86.538693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877043088, states[0] = -86.536564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896586758, states[0] = -86.535656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916414551, states[0] = -86.504272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929195799, states[0] = -86.533769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940560869, states[0] = -86.533540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949645163, states[0] = -86.527717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959401863, states[0] = -86.530555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968145451, states[0] = -38.856671, states[40]= 0.000152
Saving checkpoint... 
Iteration: 978320813, states[0] = -86.450132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986408564, states[0] = -86.502023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001694265, states[0] = -86.527243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021702188, states[0] = -86.527167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040240466, states[0] = -86.350974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053017953, states[0] = -86.537000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053885608, states[0] = -86.525703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068551580, states[0] = -86.532614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076332115, states[0] = -86.459392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085141332, states[0] = -86.534707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093930467, states[0] = -86.525392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102506990, states[0] = -86.526940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110455019, states[0] = -86.516540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118280626, states[0] = -86.408151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125656528, states[0] = -86.527574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132995609, states[0] = -86.537399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141664739, states[0] = -86.527492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148473686, states[0] = -86.520849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156750677, states[0] = -86.540358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164921156, states[0] = -86.538704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173527131, states[0] = -86.528934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182796361, states[0] = -86.540239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190378661, states[0] = -86.488778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200322268, states[0] = -86.451341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210023352, states[0] = 21.548949, states[40]= 0.006342
Saving checkpoint... 
Iteration: 1217124410, states[0] = -86.534990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224364880, states[0] = -86.481347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232725971, states[0] = -86.540237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240022548, states[0] = 21.628232, states[40]= 0.006640
Saving checkpoint... 
Iteration: 1247363558, states[0] = -86.531040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255472118, states[0] = -86.529580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264761915, states[0] = -86.540344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272259944, states[0] = -86.380355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279180570, states[0] = -86.533971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287711363, states[0] = -86.527035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297176364, states[0] = -86.534041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305223921, states[0] = -86.533218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312779398, states[0] = -86.540298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319666719, states[0] = -86.527440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325951391, states[0] = -86.525214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333947168, states[0] = -86.525240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341553215, states[0] = -86.528606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342828141, states[0] = -86.539950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355485130, states[0] = -86.529400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363184416, states[0] = -86.533888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372174819, states[0] = -67.537329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385199929, states[0] = -86.533614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393070538, states[0] = -86.535955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400560290, states[0] = -86.533401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408523187, states[0] = -86.529226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419639356, states[0] = -86.527687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430908341, states[0] = -86.538862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439915903, states[0] = -86.525425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450666443, states[0] = -86.539242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457091397, states[0] = -86.535555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466280605, states[0] = -86.408060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475217966, states[0] = -86.533288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483135311, states[0] = -86.534743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491519114, states[0] = -86.528968, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.400852
 - CaMKt in component CaMK (millimolar): 0.000884
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.039554
 - nass in component intracellular_ions (millimolar): 6.039599
 - ki in component intracellular_ions (millimolar): 145.957200
 - kss in component intracellular_ions (millimolar): 145.957189
 - cansr in component intracellular_ions (millimolar): 1.246170
 - cajsr in component intracellular_ions (millimolar): 1.246317
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008519
 - hf in component INa (dimensionless): 0.644651
 - hs in component INa (dimensionless): 0.644652
 - j in component INa (dimensionless): 0.644655
 - hsp in component INa (dimensionless): 0.395772
 - jp in component INa (dimensionless): 0.644656
 - mL in component INaL (dimensionless): 0.000249
 - hL in component INaL (dimensionless): 0.463858
 - hLp in component INaL (dimensionless): 0.274067
 - a in component Ito (dimensionless): 0.001106
 - iF in component Ito (dimensionless): 0.999423
 - iS in component Ito (dimensionless): 0.985562
 - ap in component Ito (dimensionless): 0.000564
 - iFp in component Ito (dimensionless): 0.999423
 - iSp in component Ito (dimensionless): 0.991665
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997496
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001251
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020382
 - xs1 in component IKs (dimensionless): 0.037189
 - xs2 in component IKs (dimensionless): 0.000227
 - xk1 in component IK1 (dimensionless): 0.997125
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:37:20 (88483): called boinc_finish(0)

</stderr_txt>
]]>


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