𝕏

Task 55526288

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_829_1
Workunit 26364207
Created 1 Jul 2024, 14:57:56 UTC
Sent 1 Jul 2024, 17:54:45 UTC
Report deadline 5 Jul 2024, 3:30:45 UTC
Received 4 Jul 2024, 18:02:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 34 min 18 sec
CPU time 2 hours 20 min 20 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.31 MB
Peak swap size 5.42 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_829.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_829_1_r741476130_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_829_1_r741476130_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.684441
     * GNaL_b in INaL: 0.005592
     * Gto_b in Ito: 0.084534
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032248
     * GKs_b in IKs: 0.001952
     * GK1_b in IK1: 0.160193
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.894689
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032127
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12927986, states[0] = -95.069970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28008607, states[0] = 23.381495, states[40]= 0.073544
Saving checkpoint... 
Iteration: 43099962, states[0] = -22.524678, states[40]= 0.000816
Saving checkpoint... 
Iteration: 58151830, states[0] = -80.541083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73249680, states[0] = -94.884521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88394777, states[0] = -94.980026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103428437, states[0] = -94.986237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118557822, states[0] = 8.026087, states[40]= 0.004878
Saving checkpoint... 
Iteration: 133651105, states[0] = -77.249787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148633645, states[0] = -54.789758, states[40]= 0.000012
Saving checkpoint... 
Iteration: 163064182, states[0] = 5.256397, states[40]= 0.004751
Saving checkpoint... 
Iteration: 177794817, states[0] = -94.919784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192890416, states[0] = -94.970957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207944052, states[0] = -94.984652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222898341, states[0] = -94.973230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237988813, states[0] = -94.991752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253060189, states[0] = 7.066902, states[40]= 0.004839
Saving checkpoint... 
Iteration: 268035092, states[0] = 16.836318, states[40]= 0.005556
Saving checkpoint... 
Iteration: 282563986, states[0] = 5.365216, states[40]= 0.004756
Saving checkpoint... 
Iteration: 297569972, states[0] = 2.457616, states[40]= 0.004543
Saving checkpoint... 
Iteration: 312630723, states[0] = -51.501921, states[40]= 0.000022
Saving checkpoint... 
Iteration: 327737701, states[0] = -94.854842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342670924, states[0] = -94.550584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357671167, states[0] = -94.563632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370791504, states[0] = -94.916296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385835135, states[0] = -94.946614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400872717, states[0] = -94.964140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415813487, states[0] = -94.933180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430797279, states[0] = -94.921066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445824440, states[0] = -94.940303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460852694, states[0] = -94.955546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475859977, states[0] = -94.958838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490894167, states[0] = -94.971610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505445588, states[0] = -94.984530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519743823, states[0] = -94.863524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534503236, states[0] = 35.679923, states[40]= 0.143737
Saving checkpoint... 
Iteration: 549042959, states[0] = 14.004401, states[40]= 0.005148
Saving checkpoint... 
Iteration: 564049160, states[0] = 11.619747, states[40]= 0.005002
Saving checkpoint... 
Iteration: 578412077, states[0] = -94.976777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589498864, states[0] = -94.992675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603895903, states[0] = -94.972083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615208049, states[0] = -94.803813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630071825, states[0] = 1.484363, states[40]= 0.004446
Saving checkpoint... 
Iteration: 644853620, states[0] = -94.955859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659613596, states[0] = -33.945422, states[40]= 0.000294
Saving checkpoint... 
Iteration: 674564508, states[0] = 5.124336, states[40]= 0.004743
Saving checkpoint... 
Iteration: 689278496, states[0] = -94.904162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704286905, states[0] = -94.912040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719269545, states[0] = -94.894967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734078533, states[0] = -2.462650, states[40]= 0.003892
Saving checkpoint... 
Iteration: 748998741, states[0] = -94.992557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763359781, states[0] = -94.958566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777915797, states[0] = -94.977627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792881032, states[0] = -94.966986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807591735, states[0] = -13.003750, states[40]= 0.001780
Saving checkpoint... 
Iteration: 822495118, states[0] = -94.992074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837486874, states[0] = -94.991014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851136811, states[0] = -58.214504, states[40]= 0.000007
Saving checkpoint... 
Iteration: 866076440, states[0] = -1.148100, states[40]= 0.004105
Saving checkpoint... 
Iteration: 881052086, states[0] = 10.456308, states[40]= 0.004958
Saving checkpoint... 
Iteration: 896027512, states[0] = 19.220569, states[40]= 0.006500
Saving checkpoint... 
Iteration: 911057761, states[0] = 8.113741, states[40]= 0.004879
Saving checkpoint... 
Iteration: 926041457, states[0] = 14.565484, states[40]= 0.005201
Saving checkpoint... 
Iteration: 940921031, states[0] = -94.978843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954063879, states[0] = 5.415211, states[40]= 0.004759
Saving checkpoint... 
Iteration: 964090874, states[0] = -12.210050, states[40]= 0.001919
Saving checkpoint... 
Iteration: 978472046, states[0] = -94.988812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993325504, states[0] = -94.940602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008249766, states[0] = -94.871256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023119657, states[0] = -39.916531, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1037909953, states[0] = -94.975905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052733932, states[0] = -94.848662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067588724, states[0] = -10.275591, states[40]= 0.002291
Saving checkpoint... 
Iteration: 1082483764, states[0] = -94.990438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097335260, states[0] = -94.946221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112324899, states[0] = -94.940154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126997523, states[0] = -94.992168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141898405, states[0] = -94.972505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156794473, states[0] = -94.918292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171375899, states[0] = -94.964856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186263310, states[0] = -94.887757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201105970, states[0] = -26.592874, states[40]= 0.000624
Saving checkpoint... 
Iteration: 1215973014, states[0] = -94.988806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230919765, states[0] = -94.978342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245865559, states[0] = -94.960720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260512541, states[0] = 22.434134, states[40]= 0.029833
Saving checkpoint... 
Iteration: 1275528581, states[0] = 18.911759, states[40]= 0.006305
Saving checkpoint... 
Iteration: 1290345726, states[0] = -94.951626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305362760, states[0] = -94.959504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320369182, states[0] = -94.962150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335156616, states[0] = -86.195475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350225782, states[0] = -94.835397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364612093, states[0] = -32.487809, states[40]= 0.000351
Saving checkpoint... 
Iteration: 1379553944, states[0] = 9.703073, states[40]= 0.004932
Saving checkpoint... 
Iteration: 1394076429, states[0] = -1.141224, states[40]= 0.004106
Saving checkpoint... 
Iteration: 1407546191, states[0] = 12.774860, states[40]= 0.005060
Saving checkpoint... 
Iteration: 1420884938, states[0] = -94.967954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435793249, states[0] = -94.917086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450616151, states[0] = -36.439189, states[40]= 0.000212
Saving checkpoint... 
Iteration: 1464526798, states[0] = 19.421250, states[40]= 0.006648
Saving checkpoint... 
Iteration: 1477215677, states[0] = -94.817651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492207618, states[0] = -94.802401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507281746, states[0] = -16.238500, states[40]= 0.001438
Saving checkpoint... 
Iteration: 1521816770, states[0] = -95.155832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536709977, states[0] = -49.807146, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1551574883, states[0] = -95.246401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565852056, states[0] = -94.988210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580764610, states[0] = -2.078791, states[40]= 0.004450
Saving checkpoint... 
Iteration: 1594109045, states[0] = -95.176694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608964164, states[0] = -1.838428, states[40]= 0.004497
Saving checkpoint... 
Iteration: 1623914044, states[0] = 22.455624, states[40]= 0.023695
Saving checkpoint... 
Iteration: 1638813727, states[0] = -95.187452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653687895, states[0] = -26.035386, states[40]= 0.000650
Saving checkpoint... 
Iteration: 1668682843, states[0] = -20.439719, states[40]= 0.001010
Saving checkpoint... 
Iteration: 1681580298, states[0] = -17.615616, states[40]= 0.001294
Saving checkpoint... 
Iteration: 1696221626, states[0] = 20.150177, states[40]= 0.009808
Saving checkpoint... 
Iteration: 1711117745, states[0] = -95.194631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725872309, states[0] = -95.258876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739326567, states[0] = -95.207841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752375557, states[0] = -12.431994, states[40]= 0.002126
Saving checkpoint... 
Iteration: 1767315354, states[0] = 22.073137, states[40]= 0.019077
Saving checkpoint... 
Iteration: 1782264639, states[0] = -95.251994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797126550, states[0] = -73.672426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1812027117, states[0] = 18.816567, states[40]= 0.006418
Saving checkpoint... 
Iteration: 1826892549, states[0] = -95.002919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841868006, states[0] = -94.982459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856763600, states[0] = -94.901384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871623228, states[0] = -44.118283, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1885481604, states[0] = -94.995346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900368005, states[0] = -94.964970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915151948, states[0] = -78.678323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930019929, states[0] = 21.075965, states[40]= 0.009753
Saving checkpoint... 
Iteration: 1944885101, states[0] = -94.968615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959271461, states[0] = -94.896804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974138237, states[0] = -59.864799, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1988961662, states[0] = -94.986709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003642367, states[0] = -64.728798, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2018551846, states[0] = 10.551093, states[40]= 0.004961
Saving checkpoint... 
Iteration: 2033410156, states[0] = -94.975334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048282779, states[0] = -94.907373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063144752, states[0] = -67.736946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2078020574, states[0] = 20.954066, states[40]= 0.009234
Saving checkpoint... 
Iteration: 2092930693, states[0] = -94.980331, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.867662
 - CaMKt in component CaMK (millimolar): 0.006977
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.574215
 - nass in component intracellular_ions (millimolar): 6.574275
 - ki in component intracellular_ions (millimolar): 145.402807
 - kss in component intracellular_ions (millimolar): 145.402788
 - cansr in component intracellular_ions (millimolar): 1.314116
 - cajsr in component intracellular_ions (millimolar): 1.276306
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003631
 - hf in component INa (dimensionless): 0.879406
 - hs in component INa (dimensionless): 0.879402
 - j in component INa (dimensionless): 0.879372
 - hsp in component INa (dimensionless): 0.724711
 - jp in component INa (dimensionless): 0.879353
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709366
 - hLp in component INaL (dimensionless): 0.452027
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622783
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697937
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936650
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001612
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329597
 - xs1 in component IKs (dimensionless): 0.238371
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997346
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:02:03 (9660): called boinc_finish(0)

</stderr_txt>
]]>