𝕏

Task 55526271

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_129_0
Workunit 26364199
Created 1 Jul 2024, 14:57:56 UTC
Sent 1 Jul 2024, 17:54:45 UTC
Report deadline 5 Jul 2024, 3:30:45 UTC
Received 4 Jul 2024, 17:34:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 34 min 21 sec
CPU time 2 hours 20 min 25 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.33 MB
Peak swap size 5.42 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_129.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_129_0_r1829576642_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_129_0_r1829576642_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.355264
     * GNaL_b in INaL: 0.005745
     * Gto_b in Ito: 0.087891
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031720
     * GKs_b in IKs: 0.001889
     * GK1_b in IK1: 0.166322
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.296996
     * GKb_b in IKb: 0.003784
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030894
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13505465, states[0] = 26.345552, states[40]= 0.141398
Saving checkpoint... 
Iteration: 28402092, states[0] = -95.065459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43422471, states[0] = -95.053321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58483042, states[0] = -95.054120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73543612, states[0] = 13.836514, states[40]= 0.005051
Saving checkpoint... 
Iteration: 88580779, states[0] = -3.230002, states[40]= 0.003735
Saving checkpoint... 
Iteration: 103402424, states[0] = -95.024807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117829810, states[0] = -94.993012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132315676, states[0] = -94.983208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146678574, states[0] = -94.769674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161610640, states[0] = -29.116452, states[40]= 0.000517
Saving checkpoint... 
Iteration: 174148567, states[0] = -69.866357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188437134, states[0] = -95.029158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203039882, states[0] = 15.345204, states[40]= 0.005177
Saving checkpoint... 
Iteration: 218027524, states[0] = 19.249353, states[40]= 0.006344
Saving checkpoint... 
Iteration: 232891281, states[0] = -95.016864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247866821, states[0] = -95.007978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262893049, states[0] = -95.017348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277833729, states[0] = -94.992165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292829178, states[0] = -94.989558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307843960, states[0] = -94.997546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322832581, states[0] = -94.991473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337368646, states[0] = -95.008590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352414238, states[0] = -95.023328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367282379, states[0] = -94.954875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380323650, states[0] = -94.986181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395391073, states[0] = -95.016588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410432139, states[0] = -95.027565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425496490, states[0] = -95.038182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440568721, states[0] = 3.721390, states[40]= 0.004611
Saving checkpoint... 
Iteration: 455672091, states[0] = -94.588658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470700826, states[0] = -94.837969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485804462, states[0] = -94.973144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500865949, states[0] = -95.007389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515816146, states[0] = -94.981309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530169152, states[0] = -94.292434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544970830, states[0] = -95.034612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560060311, states[0] = 7.494282, states[40]= 0.004809
Saving checkpoint... 
Iteration: 575102007, states[0] = -20.969044, states[40]= 0.000911
Saving checkpoint... 
Iteration: 590119422, states[0] = -37.432679, states[40]= 0.000190
Saving checkpoint... 
Iteration: 605170221, states[0] = -94.431573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620191138, states[0] = -94.817436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635170376, states[0] = -94.448229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649718647, states[0] = -94.871541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664826779, states[0] = -94.987878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679885147, states[0] = -95.014433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694980454, states[0] = -95.035920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709852255, states[0] = -95.001278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724879827, states[0] = -95.012545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738078163, states[0] = -1.327377, states[40]= 0.004049
Saving checkpoint... 
Iteration: 753143620, states[0] = -63.366700, states[40]= 0.000003
Saving checkpoint... 
Iteration: 768201127, states[0] = -94.838375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783101446, states[0] = -20.442854, states[40]= 0.000943
Saving checkpoint... 
Iteration: 798060446, states[0] = 7.437285, states[40]= 0.004807
Saving checkpoint... 
Iteration: 813122155, states[0] = -40.111476, states[40]= 0.000130
Saving checkpoint... 
Iteration: 828123205, states[0] = -41.156150, states[40]= 0.000111
Saving checkpoint... 
Iteration: 843115010, states[0] = -33.198364, states[40]= 0.000332
Saving checkpoint... 
Iteration: 858113379, states[0] = -31.651104, states[40]= 0.000398
Saving checkpoint... 
Iteration: 872628257, states[0] = -46.320431, states[40]= 0.000051
Saving checkpoint... 
Iteration: 886983803, states[0] = -95.036252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901753231, states[0] = -94.923020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916286653, states[0] = -94.958380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931304674, states[0] = -94.973000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945667856, states[0] = -94.050401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956745663, states[0] = -94.913149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971121234, states[0] = -39.202465, states[40]= 0.000148
Saving checkpoint... 
Iteration: 982386736, states[0] = -95.014766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997276518, states[0] = -94.948846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012070112, states[0] = 3.044379, states[40]= 0.004559
Saving checkpoint... 
Iteration: 1026856425, states[0] = -95.002966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041706297, states[0] = -94.848425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056513709, states[0] = 21.994364, states[40]= 0.023258
Saving checkpoint... 
Iteration: 1071522404, states[0] = 20.498920, states[40]= 0.007910
Saving checkpoint... 
Iteration: 1086499468, states[0] = -95.038089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101335806, states[0] = -94.992726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116231719, states[0] = -94.892831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130629051, states[0] = -47.152382, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1145187408, states[0] = -94.808189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160213095, states[0] = -94.861211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174932511, states[0] = -95.027131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189812763, states[0] = -94.978580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204808211, states[0] = -94.975389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218389371, states[0] = -95.015480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233331597, states[0] = -94.990295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248317202, states[0] = -94.981508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263285623, states[0] = -94.957226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278219375, states[0] = -94.872388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293195544, states[0] = -94.826521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308068356, states[0] = 3.896361, states[40]= 0.004624
Saving checkpoint... 
Iteration: 1321221320, states[0] = -94.875720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331232557, states[0] = -94.893980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345618944, states[0] = -36.968843, states[40]= 0.000203
Saving checkpoint... 
Iteration: 1360461011, states[0] = -95.032488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375390750, states[0] = -95.015822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390241504, states[0] = -94.907120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404967876, states[0] = -95.033574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419798890, states[0] = -94.968260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434667545, states[0] = -93.976656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449646657, states[0] = -67.204416, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1464492999, states[0] = -95.037056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479456485, states[0] = -95.031631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494201687, states[0] = -94.839008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509110492, states[0] = -46.293263, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1523939199, states[0] = -95.224372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538479027, states[0] = -13.805264, states[40]= 0.001848
Saving checkpoint... 
Iteration: 1553229894, states[0] = -75.305823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567991111, states[0] = -95.171941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582837426, states[0] = 13.840143, states[40]= 0.006182
Saving checkpoint... 
Iteration: 1597688575, states[0] = -95.171844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612504262, states[0] = 31.577833, states[40]= 0.136179
Saving checkpoint... 
Iteration: 1627077445, states[0] = -95.148748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641996171, states[0] = -33.453101, states[40]= 0.000317
Saving checkpoint... 
Iteration: 1656794682, states[0] = -95.187118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671736294, states[0] = -88.275636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686667694, states[0] = -3.901298, states[40]= 0.004068
Saving checkpoint... 
Iteration: 1701412583, states[0] = -52.353443, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1716383145, states[0] = -19.337771, states[40]= 0.001110
Saving checkpoint... 
Iteration: 1730611317, states[0] = -95.217780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745421396, states[0] = 20.186368, states[40]= 0.009743
Saving checkpoint... 
Iteration: 1759814736, states[0] = 22.072333, states[40]= 0.020784
Saving checkpoint... 
Iteration: 1773181917, states[0] = -95.160254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786490767, states[0] = -95.305401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801367194, states[0] = -95.072601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816166287, states[0] = -94.381684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829933806, states[0] = -95.055229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842742253, states[0] = -94.927623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857671067, states[0] = -94.594973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872705884, states[0] = -94.855193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887198022, states[0] = -94.836537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902082377, states[0] = -4.172142, states[40]= 0.003554
Saving checkpoint... 
Iteration: 1916966326, states[0] = -95.035081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931303194, states[0] = -94.972587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946228790, states[0] = -94.888532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959764699, states[0] = -94.936389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974692027, states[0] = -94.818835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989712595, states[0] = -94.859925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004546528, states[0] = 12.932093, states[40]= 0.004983
Saving checkpoint... 
Iteration: 2019461471, states[0] = -95.032167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034464042, states[0] = -95.032543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047383268, states[0] = -95.012852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061984452, states[0] = -95.035519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076796365, states[0] = -94.965769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091550423, states[0] = 11.461301, states[40]= 0.004924
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.913295
 - CaMKt in component CaMK (millimolar): 0.007103
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.590390
 - nass in component intracellular_ions (millimolar): 6.590450
 - ki in component intracellular_ions (millimolar): 145.385138
 - kss in component intracellular_ions (millimolar): 145.385118
 - cansr in component intracellular_ions (millimolar): 1.319713
 - cajsr in component intracellular_ions (millimolar): 1.281542
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003614
 - hf in component INa (dimensionless): 0.880199
 - hs in component INa (dimensionless): 0.880195
 - j in component INa (dimensionless): 0.880166
 - hsp in component INa (dimensionless): 0.726204
 - jp in component INa (dimensionless): 0.880146
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710089
 - hLp in component INaL (dimensionless): 0.451966
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620720
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695611
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935465
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001631
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329850
 - xs1 in component IKs (dimensionless): 0.242010
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:34:25 (2012): called boinc_finish(0)

</stderr_txt>
]]>