𝕏

Task 55526211

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_129_0
Workunit 26364169
Created 1 Jul 2024, 14:57:56 UTC
Sent 1 Jul 2024, 17:54:30 UTC
Report deadline 4 Jul 2024, 17:54:30 UTC
Received 4 Jul 2024, 15:53:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228543
Run time 1 hours 35 min 39 sec
CPU time 28 min 7 sec
Validate state Valid
Credit 42.77
Device peak FLOPS 5.62 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.58 MB
Peak swap size 391.75 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.20.7</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_129.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_129_0_r1471258439_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_129_0_r1471258439_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.355264
     * GNaL_b in INaL: 0.005745
     * Gto_b in Ito: 0.087891
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031720
     * GKs_b in IKs: 0.001889
     * GK1_b in IK1: 0.166322
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.296996
     * GKb_b in IKb: 0.003784
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030894
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 20972392, states[0] = -87.726132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38172973, states[0] = 22.309866, states[40]= 0.045981
Saving checkpoint... 
Iteration: 52865824, states[0] = 8.039406, states[40]= 0.007261
Saving checkpoint... 
Iteration: 69430702, states[0] = -80.669085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88305375, states[0] = -87.758865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105849288, states[0] = 15.070436, states[40]= 0.008583
Saving checkpoint... 
Iteration: 122596681, states[0] = -85.514154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140724450, states[0] = -31.915381, states[40]= 0.000432
Saving checkpoint... 
Iteration: 154974825, states[0] = -87.791096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174643307, states[0] = -87.802161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187707397, states[0] = -14.586029, states[40]= 0.002142
Saving checkpoint... 
Iteration: 195170006, states[0] = 16.996755, states[40]= 0.009622
Saving checkpoint... 
Iteration: 208525417, states[0] = 1.115630, states[40]= 0.006254
Saving checkpoint... 
Iteration: 218184519, states[0] = 6.557078, states[40]= 0.007086
Saving checkpoint... 
Iteration: 229010297, states[0] = 11.062494, states[40]= 0.007684
Saving checkpoint... 
Iteration: 238176092, states[0] = 11.033387, states[40]= 0.007679
Saving checkpoint... 
Iteration: 246477311, states[0] = 39.381492, states[40]= 0.083360
Saving checkpoint... 
Iteration: 254149768, states[0] = 23.107681, states[40]= 0.064733
Saving checkpoint... 
Iteration: 264092728, states[0] = -87.557208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272078484, states[0] = -82.685306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293947933, states[0] = -87.748626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309987416, states[0] = 19.038762, states[40]= 0.012682
Saving checkpoint... 
Iteration: 325929029, states[0] = -87.681364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340931932, states[0] = -87.703734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353843932, states[0] = 1.374019, states[40]= 0.006302
Saving checkpoint... 
Iteration: 367464107, states[0] = 39.887108, states[40]= 0.018085
Saving checkpoint... 
Iteration: 382255694, states[0] = -87.674813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398974884, states[0] = 20.474789, states[40]= 0.019485
Saving checkpoint... 
Iteration: 414644024, states[0] = 18.865380, states[40]= 0.012245
Saving checkpoint... 
Iteration: 427677227, states[0] = -6.356522, states[40]= 0.004371
Saving checkpoint... 
Iteration: 443591303, states[0] = -87.716361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458340498, states[0] = -5.957279, states[40]= 0.004490
Saving checkpoint... 
Iteration: 467782369, states[0] = -87.806583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476307382, states[0] = 17.568827, states[40]= 0.010153
Saving checkpoint... 
Iteration: 484971579, states[0] = 18.313013, states[40]= 0.011149
Saving checkpoint... 
Iteration: 493112586, states[0] = -87.804931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505010707, states[0] = -17.002856, states[40]= 0.001689
Saving checkpoint... 
Iteration: 513159503, states[0] = 2.979768, states[40]= 0.006579
Saving checkpoint... 
Iteration: 520648431, states[0] = 10.649988, states[40]= 0.007622
Saving checkpoint... 
Iteration: 529273090, states[0] = -87.797694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538431131, states[0] = -87.774236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545908120, states[0] = -87.687208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556635400, states[0] = 16.209559, states[40]= 0.009096
Saving checkpoint... 
Iteration: 572017036, states[0] = -35.210820, states[40]= 0.000298
Saving checkpoint... 
Iteration: 592161313, states[0] = -7.019666, states[40]= 0.004173
Saving checkpoint... 
Iteration: 608565463, states[0] = -87.668162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623520701, states[0] = -47.389100, states[40]= 0.000057
Saving checkpoint... 
Iteration: 638744904, states[0] = -87.741318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652773065, states[0] = 27.223871, states[40]= 0.121479
Saving checkpoint... 
Iteration: 670809291, states[0] = 3.908921, states[40]= 0.006723
Saving checkpoint... 
Iteration: 685713330, states[0] = -87.324943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698787534, states[0] = 16.374194, states[40]= 0.009191
Saving checkpoint... 
Iteration: 711955833, states[0] = 14.783970, states[40]= 0.008486
Saving checkpoint... 
Iteration: 727164263, states[0] = -29.801113, states[40]= 0.000535
Saving checkpoint... 
Iteration: 744185438, states[0] = -62.256226, states[40]= 0.000006
Saving checkpoint... 
Iteration: 757362879, states[0] = -82.194922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773214177, states[0] = -87.655803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787807263, states[0] = -5.615237, states[40]= 0.004591
Saving checkpoint... 
Iteration: 802099161, states[0] = 21.236142, states[40]= 0.027529
Saving checkpoint... 
Iteration: 818484999, states[0] = -24.973062, states[40]= 0.000825
Saving checkpoint... 
Iteration: 834509766, states[0] = -62.299551, states[40]= 0.000006
Saving checkpoint... 
Iteration: 847873782, states[0] = -87.659241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862625920, states[0] = 1.790203, states[40]= 0.006378
Saving checkpoint... 
Iteration: 875693497, states[0] = -87.229825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889543166, states[0] = -87.700289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905282660, states[0] = 6.413778, states[40]= 0.007067
Saving checkpoint... 
Iteration: 922583958, states[0] = 22.530175, states[40]= 0.051871
Saving checkpoint... 
Iteration: 936392558, states[0] = -87.777524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953139538, states[0] = -26.845537, states[40]= 0.000702
Saving checkpoint... 
Iteration: 974162571, states[0] = -62.464465, states[40]= 0.000006
Saving checkpoint... 
Iteration: 990601769, states[0] = 10.427917, states[40]= 0.007590
Saving checkpoint... 
Iteration: 1003603239, states[0] = 8.540374, states[40]= 0.007338
Saving checkpoint... 
Iteration: 1019591344, states[0] = 15.001708, states[40]= 0.008560
Saving checkpoint... 
Iteration: 1038726183, states[0] = -87.808299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054944452, states[0] = -2.508638, states[40]= 0.005450
Saving checkpoint... 
Iteration: 1074710285, states[0] = -87.771754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085663166, states[0] = -81.928021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103275359, states[0] = -5.199262, states[40]= 0.004712
Saving checkpoint... 
Iteration: 1122973080, states[0] = -50.677618, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1138114337, states[0] = -17.402610, states[40]= 0.001624
Saving checkpoint... 
Iteration: 1159565982, states[0] = 20.288398, states[40]= 0.018126
Saving checkpoint... 
Iteration: 1175443527, states[0] = -16.816033, states[40]= 0.001720
Saving checkpoint... 
Iteration: 1193860600, states[0] = -87.756749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213388908, states[0] = 22.202533, states[40]= 0.044739
Saving checkpoint... 
Iteration: 1230887472, states[0] = 22.066568, states[40]= 0.041904
Saving checkpoint... 
Iteration: 1248327378, states[0] = -87.547607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263032913, states[0] = -87.796355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277890823, states[0] = 18.951847, states[40]= 0.012454
Saving checkpoint... 
Iteration: 1293362246, states[0] = -87.793507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311753047, states[0] = -3.531856, states[40]= 0.005181
Saving checkpoint... 
Iteration: 1316518195, states[0] = -87.767358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334741151, states[0] = 5.305643, states[40]= 0.006921
Saving checkpoint... 
Iteration: 1344741473, states[0] = 4.251245, states[40]= 0.006773
Saving checkpoint... 
Iteration: 1356459375, states[0] = -65.204889, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1367081719, states[0] = -4.512713, states[40]= 0.004909
Saving checkpoint... 
Iteration: 1378692681, states[0] = -87.809232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389433617, states[0] = -32.912802, states[40]= 0.000388
Saving checkpoint... 
Iteration: 1399849079, states[0] = -87.785794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409847866, states[0] = -87.785125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416344262, states[0] = -87.775933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422815619, states[0] = -87.652507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431337080, states[0] = -87.757140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438571394, states[0] = -1.108723, states[40]= 0.005789
Saving checkpoint... 
Iteration: 1447559052, states[0] = 8.390503, states[40]= 0.007319
Saving checkpoint... 
Iteration: 1460158960, states[0] = -87.725662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469107814, states[0] = -54.536622, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1478259210, states[0] = -34.483042, states[40]= 0.000325
Saving checkpoint... 
Iteration: 1490801563, states[0] = -87.478732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499818380, states[0] = -87.712280, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.691999
 - CaMKt in component CaMK (millimolar): 0.043313
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.017541
 - nass in component intracellular_ions (millimolar): 7.017690
 - ki in component intracellular_ions (millimolar): 144.900394
 - kss in component intracellular_ions (millimolar): 144.900362
 - cansr in component intracellular_ions (millimolar): 1.630295
 - cajsr in component intracellular_ions (millimolar): 1.193572
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007482
 - hf in component INa (dimensionless): 0.691641
 - hs in component INa (dimensionless): 0.691403
 - j in component INa (dimensionless): 0.680787
 - hsp in component INa (dimensionless): 0.446390
 - jp in component INa (dimensionless): 0.654142
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.292281
 - hLp in component INaL (dimensionless): 0.135749
 - a in component Ito (dimensionless): 0.001014
 - iF in component Ito (dimensionless): 0.999539
 - iS in component Ito (dimensionless): 0.175282
 - ap in component Ito (dimensionless): 0.000517
 - iFp in component Ito (dimensionless): 0.999539
 - iSp in component Ito (dimensionless): 0.212095
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804369
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966867
 - jca in component ICaL (dimensionless): 0.947715
 - ffp in component ICaL (dimensionless): 0.999860
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009571
 - xrf in component IKr (dimensionless): 0.028675
 - xrs in component IKr (dimensionless): 0.787089
 - xs1 in component IKs (dimensionless): 0.459281
 - xs2 in component IKs (dimensionless): 0.001202
 - xk1 in component IK1 (dimensionless): 0.996814
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:53:28 (29912): called boinc_finish(0)

</stderr_txt>
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