𝕏

Task 55518709

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_22_1
Workunit 26360460
Created 1 Jul 2024, 14:54:18 UTC
Sent 1 Jul 2024, 17:10:38 UTC
Report deadline 4 Jul 2024, 17:10:38 UTC
Received 2 Jul 2024, 4:27:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226666
Run time 2 hours 48 min 27 sec
CPU time 2 hours 40 min 54 sec
Validate state Valid
Credit 41.97
Device peak FLOPS 2.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.13 MB
Peak swap size 10.95 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_22.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_22_1_r738209212_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_22_1_r738209212_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.595932
     * GNaL_b in INaL: 0.006228
     * Gto_b in Ito: 0.085971
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032208
     * GKs_b in IKs: 0.001911
     * GK1_b in IK1: 0.159548
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.366170
     * GKb_b in IKb: 0.003796
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032908
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9711511, states[0] = 1.387471, states[40]= 0.005900
Saving checkpoint... 
Iteration: 19167077, states[0] = 37.567594, states[40]= 0.076767
Saving checkpoint... 
Iteration: 28474762, states[0] = -87.747169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37708210, states[0] = 2.045826, states[40]= 0.006378
Saving checkpoint... 
Iteration: 46942531, states[0] = -87.061202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55805660, states[0] = -87.752707, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_22.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_22_1_r738209212_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_22_1_r738209212_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.595932
     * GNaL_b in INaL: 0.006228
     * Gto_b in Ito: 0.085971
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032208
     * GKs_b in IKs: 0.001911
     * GK1_b in IK1: 0.159548
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.366170
     * GKb_b in IKb: 0.003796
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032908
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 55805660
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.752707 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 66694313, states[0] = 10.369195, states[40]= 0.007622
Saving checkpoint... 
Iteration: 77179028, states[0] = 18.426293, states[40]= 0.011370
Saving checkpoint... 
Iteration: 88206559, states[0] = -1.297530, states[40]= 0.005729
Saving checkpoint... 
Iteration: 99344631, states[0] = 17.875727, states[40]= 0.010590
Saving checkpoint... 
Iteration: 110140747, states[0] = -87.782532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121085434, states[0] = -69.669667, states[40]= 0.000002
Saving checkpoint... 
Iteration: 131550765, states[0] = -21.094270, states[40]= 0.001145
Saving checkpoint... 
Iteration: 142889058, states[0] = -29.677702, states[40]= 0.000535
Saving checkpoint... 
Iteration: 153753993, states[0] = -78.435057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164521413, states[0] = 7.859031, states[40]= 0.007275
Saving checkpoint... 
Iteration: 175038347, states[0] = -9.764363, states[40]= 0.003349
Saving checkpoint... 
Iteration: 185567776, states[0] = -52.427540, states[40]= 0.000026
Saving checkpoint... 
Iteration: 195942558, states[0] = -87.689492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206585173, states[0] = -82.749668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217882606, states[0] = -31.141071, states[40]= 0.000462
Saving checkpoint... 
Iteration: 228878511, states[0] = -26.962722, states[40]= 0.000688
Saving checkpoint... 
Iteration: 240065838, states[0] = -57.543908, states[40]= 0.000012
Saving checkpoint... 
Iteration: 250956004, states[0] = -87.769689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261687824, states[0] = 0.035849, states[40]= 0.006028
Saving checkpoint... 
Iteration: 272284378, states[0] = -87.759680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283140506, states[0] = 38.537205, states[40]= 0.087268
Saving checkpoint... 
Iteration: 294217895, states[0] = -44.404599, states[40]= 0.000087
Saving checkpoint... 
Iteration: 304922805, states[0] = -87.573052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315889165, states[0] = -54.005099, states[40]= 0.000021
Saving checkpoint... 
Iteration: 326525478, states[0] = -12.891913, states[40]= 0.002518
Saving checkpoint... 
Iteration: 337594751, states[0] = -87.687568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348268953, states[0] = -87.729447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358865305, states[0] = -26.679152, states[40]= 0.000705
Saving checkpoint... 
Iteration: 369513519, states[0] = -3.189832, states[40]= 0.005258
Saving checkpoint... 
Iteration: 380201816, states[0] = -34.062186, states[40]= 0.000336
Saving checkpoint... 
Iteration: 390739118, states[0] = -86.564932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401387263, states[0] = -64.003030, states[40]= 0.000004
Saving checkpoint... 
Iteration: 412187146, states[0] = -17.946932, states[40]= 0.001535
Saving checkpoint... 
Iteration: 422886597, states[0] = -66.391349, states[40]= 0.000003
Saving checkpoint... 
Iteration: 433567643, states[0] = -86.388363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444127174, states[0] = 27.701661, states[40]= 0.118764
Saving checkpoint... 
Iteration: 454579510, states[0] = -87.659652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465249710, states[0] = -87.693540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475351776, states[0] = -24.030213, states[40]= 0.000887
Saving checkpoint... 
Iteration: 485829467, states[0] = 2.423582, states[40]= 0.006482
Saving checkpoint... 
Iteration: 496333663, states[0] = -2.640313, states[40]= 0.005401
Saving checkpoint... 
Iteration: 507065921, states[0] = -87.412584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517509178, states[0] = -16.851290, states[40]= 0.001708
Saving checkpoint... 
Iteration: 528104782, states[0] = -87.801266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538438785, states[0] = -87.806411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548841960, states[0] = -20.530921, states[40]= 0.001205
Saving checkpoint... 
Iteration: 559357689, states[0] = -43.904647, states[40]= 0.000093
Saving checkpoint... 
Iteration: 569738726, states[0] = -87.690434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580078271, states[0] = -87.725695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590227295, states[0] = -87.563137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600503488, states[0] = -20.574156, states[40]= 0.001200
Saving checkpoint... 
Iteration: 610924199, states[0] = -87.783554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621094741, states[0] = -87.799038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631219486, states[0] = -87.357076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641737319, states[0] = -87.719379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650297361, states[0] = 13.645179, states[40]= 0.008249
Saving checkpoint... 
Iteration: 659061324, states[0] = -87.678589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667694111, states[0] = -64.240054, states[40]= 0.000004
Saving checkpoint... 
Iteration: 676146580, states[0] = -0.163879, states[40]= 0.005985
Saving checkpoint... 
Iteration: 684762934, states[0] = -87.821842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693417343, states[0] = -87.787920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701913112, states[0] = -87.776745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710668332, states[0] = -33.466074, states[40]= 0.000359
Saving checkpoint... 
Iteration: 719539482, states[0] = -86.537230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728150331, states[0] = -10.618328, states[40]= 0.003108
Saving checkpoint... 
Iteration: 736729439, states[0] = -87.726067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745091027, states[0] = -87.823786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753409177, states[0] = -87.780665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762281208, states[0] = 16.424897, states[40]= 0.009330
Saving checkpoint... 
Iteration: 771106823, states[0] = 19.632998, states[40]= 0.014436
Saving checkpoint... 
Iteration: 780051680, states[0] = -87.693823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789982005, states[0] = -16.960660, states[40]= 0.001690
Saving checkpoint... 
Iteration: 799790367, states[0] = 8.465775, states[40]= 0.007357
Saving checkpoint... 
Iteration: 809912242, states[0] = -87.807777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820210702, states[0] = -87.669126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830364539, states[0] = -87.160377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840489437, states[0] = -34.503044, states[40]= 0.000319
Saving checkpoint... 
Iteration: 850448503, states[0] = 10.834350, states[40]= 0.007699
Saving checkpoint... 
Iteration: 860173536, states[0] = -62.155260, states[40]= 0.000006
Saving checkpoint... 
Iteration: 869631316, states[0] = -4.473832, states[40]= 0.004905
Saving checkpoint... 
Iteration: 879401203, states[0] = -87.795332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889004041, states[0] = -62.240460, states[40]= 0.000006
Saving checkpoint... 
Iteration: 898500163, states[0] = -57.801542, states[40]= 0.000011
Saving checkpoint... 
Iteration: 907792439, states[0] = -2.558906, states[40]= 0.005422
Saving checkpoint... 
Iteration: 917418709, states[0] = 22.321613, states[40]= 0.042941
Saving checkpoint... 
Iteration: 926951351, states[0] = 3.001433, states[40]= 0.006579
Saving checkpoint... 
Iteration: 936562342, states[0] = -87.795847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946440618, states[0] = 9.684347, states[40]= 0.007526
Saving checkpoint... 
Iteration: 956377052, states[0] = -87.737631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966210531, states[0] = -87.742044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975977973, states[0] = -37.380761, states[40]= 0.000225
Saving checkpoint... 
Iteration: 985843349, states[0] = -85.200198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995828784, states[0] = -65.555116, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1005868440, states[0] = -87.722507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015661659, states[0] = -68.059329, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1025672302, states[0] = -84.928188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035476847, states[0] = -44.049569, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1045296586, states[0] = -26.575243, states[40]= 0.000712
Saving checkpoint... 
Iteration: 1055330710, states[0] = -78.777647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065532598, states[0] = -87.736755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075902198, states[0] = 22.629611, states[40]= 0.049205
Saving checkpoint... 
Iteration: 1086077346, states[0] = 18.761840, states[40]= 0.012015
Saving checkpoint... 
Iteration: 1096376336, states[0] = -87.785129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106572876, states[0] = 19.795607, states[40]= 0.015075
Saving checkpoint... 
Iteration: 1116636804, states[0] = -46.024797, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1126791327, states[0] = -30.618231, states[40]= 0.000487
Saving checkpoint... 
Iteration: 1137022610, states[0] = -87.725138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146997635, states[0] = -86.793313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157038417, states[0] = -87.789841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167011636, states[0] = -87.685430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177185222, states[0] = -87.724926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187325979, states[0] = -86.520585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197418480, states[0] = 7.589869, states[40]= 0.007240
Saving checkpoint... 
Iteration: 1207604267, states[0] = -13.225460, states[40]= 0.002438
Saving checkpoint... 
Iteration: 1217539426, states[0] = -87.811156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227679648, states[0] = -87.722634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237737811, states[0] = 14.118012, states[40]= 0.008374
Saving checkpoint... 
Iteration: 1247763809, states[0] = -8.983507, states[40]= 0.003575
Saving checkpoint... 
Iteration: 1257821116, states[0] = -87.052641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268136373, states[0] = -68.002614, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1278096298, states[0] = -11.945225, states[40]= 0.002754
Saving checkpoint... 
Iteration: 1288364990, states[0] = -87.809077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298271535, states[0] = -26.932911, states[40]= 0.000690
Saving checkpoint... 
Iteration: 1308328609, states[0] = -87.669152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318382336, states[0] = 20.850462, states[40]= 0.021651
Saving checkpoint... 
Iteration: 1328390890, states[0] = 16.616153, states[40]= 0.009451
Saving checkpoint... 
Iteration: 1338511383, states[0] = -87.759509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348593502, states[0] = -17.956111, states[40]= 0.001534
Saving checkpoint... 
Iteration: 1358510296, states[0] = -87.762754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368869778, states[0] = 24.901330, states[40]= 0.092276
Saving checkpoint... 
Iteration: 1379100867, states[0] = -32.615810, states[40]= 0.000395
Saving checkpoint... 
Iteration: 1389545170, states[0] = 19.550807, states[40]= 0.014144
Saving checkpoint... 
Iteration: 1399702436, states[0] = 23.002529, states[40]= 0.057056
Saving checkpoint... 
Iteration: 1409906879, states[0] = -0.502678, states[40]= 0.005912
Saving checkpoint... 
Iteration: 1420215565, states[0] = 16.342618, states[40]= 0.009280
Saving checkpoint... 
Iteration: 1430472205, states[0] = -87.288169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440878250, states[0] = 17.322665, states[40]= 0.010005
Saving checkpoint... 
Iteration: 1451202172, states[0] = 20.932673, states[40]= 0.022406
Saving checkpoint... 
Iteration: 1461519141, states[0] = -87.822195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471756330, states[0] = -29.921026, states[40]= 0.000522
Saving checkpoint... 
Iteration: 1482058130, states[0] = 6.513243, states[40]= 0.007095
Saving checkpoint... 
Iteration: 1492330566, states[0] = -87.763540, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.701442
 - CaMKt in component CaMK (millimolar): 0.041993
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 6.987320
 - nass in component intracellular_ions (millimolar): 6.987469
 - ki in component intracellular_ions (millimolar): 144.934215
 - kss in component intracellular_ions (millimolar): 144.934183
 - cansr in component intracellular_ions (millimolar): 1.614841
 - cajsr in component intracellular_ions (millimolar): 1.184804
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007475
 - hf in component INa (dimensionless): 0.691972
 - hs in component INa (dimensionless): 0.691728
 - j in component INa (dimensionless): 0.681032
 - hsp in component INa (dimensionless): 0.446746
 - jp in component INa (dimensionless): 0.654336
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.292322
 - hLp in component INaL (dimensionless): 0.135728
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999539
 - iS in component Ito (dimensionless): 0.175658
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999540
 - iSp in component Ito (dimensionless): 0.212496
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804294
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966851
 - jca in component ICaL (dimensionless): 0.948034
 - ffp in component ICaL (dimensionless): 0.999864
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009411
 - xrf in component IKr (dimensionless): 0.028786
 - xrs in component IKr (dimensionless): 0.788840
 - xs1 in component IKs (dimensionless): 0.458725
 - xs2 in component IKs (dimensionless): 0.001193
 - xk1 in component IK1 (dimensionless): 0.996811
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:27:00 (898): called boinc_finish(0)

</stderr_txt>
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