𝕏

Task 55518706

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_122_0
Workunit 26360459
Created 1 Jul 2024, 14:54:13 UTC
Sent 1 Jul 2024, 17:10:38 UTC
Report deadline 4 Jul 2024, 17:10:38 UTC
Received 2 Jul 2024, 1:30:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226666
Run time 2 hours 49 min 51 sec
CPU time 2 hours 40 min 36 sec
Validate state Valid
Credit 42.71
Device peak FLOPS 2.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.20 MB
Peak swap size 10.95 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_122.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_122_0_r582174265_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_333-conf_122_0_r582174265_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.866614
     * GNaL_b in INaL: 0.005618
     * Gto_b in Ito: 0.085963
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031930
     * GKs_b in IKs: 0.001901
     * GK1_b in IK1: 0.167496
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.313680
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032529
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9916240, states[0] = -49.331549, states[40]= 0.000034
Saving checkpoint... 
Iteration: 19882759, states[0] = -4.086977, states[40]= 0.004873
Saving checkpoint... 
Iteration: 29744057, states[0] = -43.808931, states[40]= 0.000092
Saving checkpoint... 
Iteration: 40099471, states[0] = -80.263728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50071622, states[0] = -38.739254, states[40]= 0.000189
Saving checkpoint... 
Iteration: 60221033, states[0] = -15.984172, states[40]= 0.001860
Saving checkpoint... 
Iteration: 70210593, states[0] = -3.668810, states[40]= 0.005128
Saving checkpoint... 
Iteration: 79853030, states[0] = 14.450104, states[40]= 0.008418
Saving checkpoint... 
Iteration: 89515545, states[0] = 16.203529, states[40]= 0.009133
Saving checkpoint... 
Iteration: 99114213, states[0] = -87.694533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108659119, states[0] = 32.510523, states[40]= 0.121799
Saving checkpoint... 
Iteration: 118376502, states[0] = -8.665518, states[40]= 0.003673
Saving checkpoint... 
Iteration: 128035150, states[0] = -0.586626, states[40]= 0.005895
Saving checkpoint... 
Iteration: 137650308, states[0] = -87.850682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147273577, states[0] = -87.667529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156908029, states[0] = -58.684008, states[40]= 0.000010
Saving checkpoint... 
Iteration: 166633726, states[0] = -87.810881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176396959, states[0] = -45.429666, states[40]= 0.000075
Saving checkpoint... 
Iteration: 186048704, states[0] = -25.977873, states[40]= 0.000752
Saving checkpoint... 
Iteration: 195750991, states[0] = -81.238051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205454394, states[0] = -87.780717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215105601, states[0] = -87.717307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224692784, states[0] = -1.225339, states[40]= 0.005751
Saving checkpoint... 
Iteration: 234328978, states[0] = 18.820050, states[40]= 0.012083
Saving checkpoint... 
Iteration: 243884429, states[0] = -37.373594, states[40]= 0.000226
Saving checkpoint... 
Iteration: 253547949, states[0] = -34.356386, states[40]= 0.000326
Saving checkpoint... 
Iteration: 263227402, states[0] = -53.725426, states[40]= 0.000022
Saving checkpoint... 
Iteration: 272786948, states[0] = -87.801484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282403300, states[0] = -71.615780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292146363, states[0] = 23.012149, states[40]= 0.059005
Saving checkpoint... 
Iteration: 301697000, states[0] = -16.295430, states[40]= 0.001807
Saving checkpoint... 
Iteration: 311384220, states[0] = -46.507327, states[40]= 0.000064
Saving checkpoint... 
Iteration: 321117317, states[0] = -87.807684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330812278, states[0] = 21.607077, states[40]= 0.031250
Saving checkpoint... 
Iteration: 340494386, states[0] = 13.990644, states[40]= 0.008291
Saving checkpoint... 
Iteration: 350248946, states[0] = -87.555808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359828669, states[0] = 12.245040, states[40]= 0.007906
Saving checkpoint... 
Iteration: 369543379, states[0] = -44.126262, states[40]= 0.000091
Saving checkpoint... 
Iteration: 379052351, states[0] = -58.493313, states[40]= 0.000010
Saving checkpoint... 
Iteration: 388745963, states[0] = -87.589392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398256726, states[0] = -87.732136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407999298, states[0] = 6.176942, states[40]= 0.007038
Saving checkpoint... 
Iteration: 417634453, states[0] = 22.669019, states[40]= 0.051559
Saving checkpoint... 
Iteration: 427230888, states[0] = -84.632844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437036806, states[0] = -44.372454, states[40]= 0.000088
Saving checkpoint... 
Iteration: 446322246, states[0] = 10.818083, states[40]= 0.007667
Saving checkpoint... 
Iteration: 455790433, states[0] = 35.462397, states[40]= 0.108528
Saving checkpoint... 
Iteration: 465432712, states[0] = -87.795639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475357978, states[0] = -32.799546, states[40]= 0.000388
Saving checkpoint... 
Iteration: 485122960, states[0] = 27.798985, states[40]= 0.121625
Saving checkpoint... 
Iteration: 494929900, states[0] = -87.796064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504812578, states[0] = 13.223246, states[40]= 0.008104
Saving checkpoint... 
Iteration: 514661630, states[0] = 0.861566, states[40]= 0.006196
Saving checkpoint... 
Iteration: 524432439, states[0] = -87.814080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534369145, states[0] = -56.974001, states[40]= 0.000013
Saving checkpoint... 
Iteration: 544170029, states[0] = -12.447414, states[40]= 0.002631
Saving checkpoint... 
Iteration: 554039526, states[0] = -65.934548, states[40]= 0.000003
Saving checkpoint... 
Iteration: 563897912, states[0] = -87.656987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573833467, states[0] = -12.081958, states[40]= 0.002723
Saving checkpoint... 
Iteration: 583772053, states[0] = -87.849644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593652148, states[0] = 2.289843, states[40]= 0.006457
Saving checkpoint... 
Iteration: 603325528, states[0] = -5.577826, states[40]= 0.004592
Saving checkpoint... 
Iteration: 613122298, states[0] = 19.721495, states[40]= 0.014778
Saving checkpoint... 
Iteration: 623018860, states[0] = -45.294073, states[40]= 0.000077
Saving checkpoint... 
Iteration: 632702621, states[0] = -73.448351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642540153, states[0] = -81.936366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652326672, states[0] = -13.556476, states[40]= 0.002365
Saving checkpoint... 
Iteration: 662091790, states[0] = -87.833565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671812787, states[0] = 0.667124, states[40]= 0.006157
Saving checkpoint... 
Iteration: 681620752, states[0] = 17.336932, states[40]= 0.009950
Saving checkpoint... 
Iteration: 691295151, states[0] = 12.473977, states[40]= 0.007949
Saving checkpoint... 
Iteration: 700863234, states[0] = -74.815806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710516027, states[0] = -53.764695, states[40]= 0.000022
Saving checkpoint... 
Iteration: 720222624, states[0] = -87.721746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729819404, states[0] = -14.236410, states[40]= 0.002213
Saving checkpoint... 
Iteration: 739557647, states[0] = -87.739834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749276870, states[0] = 19.085032, states[40]= 0.012711
Saving checkpoint... 
Iteration: 759054216, states[0] = -87.732829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768769681, states[0] = 21.153413, states[40]= 0.025098
Saving checkpoint... 
Iteration: 778531092, states[0] = -85.947850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788430230, states[0] = 22.919132, states[40]= 0.056970
Saving checkpoint... 
Iteration: 798076365, states[0] = -87.827882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807734946, states[0] = -87.805679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817034059, states[0] = -87.469672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826220994, states[0] = -87.762224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835365308, states[0] = -87.451682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844567992, states[0] = -87.816488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853842377, states[0] = -65.099097, states[40]= 0.000004
Saving checkpoint... 
Iteration: 863031568, states[0] = -87.577987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872166101, states[0] = -53.139626, states[40]= 0.000024
Saving checkpoint... 
Iteration: 881343494, states[0] = -71.776199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890630213, states[0] = -5.675509, states[40]= 0.004563
Saving checkpoint... 
Iteration: 899826432, states[0] = -48.009488, states[40]= 0.000052
Saving checkpoint... 
Iteration: 908913357, states[0] = 29.224323, states[40]= 0.125860
Saving checkpoint... 
Iteration: 918053554, states[0] = -87.793105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927242917, states[0] = 37.380875, states[40]= 0.096491
Saving checkpoint... 
Iteration: 936364287, states[0] = -87.698648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945416300, states[0] = 22.077804, states[40]= 0.039405
Saving checkpoint... 
Iteration: 954658278, states[0] = -53.762969, states[40]= 0.000022
Saving checkpoint... 
Iteration: 963706451, states[0] = -87.758880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972830164, states[0] = -64.582764, states[40]= 0.000004
Saving checkpoint... 
Iteration: 982067167, states[0] = -87.853215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988924215, states[0] = 16.906790, states[40]= 0.009590
Saving checkpoint... 
Iteration: 998573047, states[0] = 25.300647, states[40]= 0.100062
Saving checkpoint... 
Iteration: 1008389127, states[0] = -87.828966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018140507, states[0] = -37.621496, states[40]= 0.000219
Saving checkpoint... 
Iteration: 1027988732, states[0] = -60.459499, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1037821606, states[0] = -61.278518, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1047569137, states[0] = 24.222049, states[40]= 0.083314
Saving checkpoint... 
Iteration: 1057323174, states[0] = -67.024143, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1067092952, states[0] = 11.174191, states[40]= 0.007722
Saving checkpoint... 
Iteration: 1076879295, states[0] = -87.820004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086590417, states[0] = 11.549562, states[40]= 0.007784
Saving checkpoint... 
Iteration: 1096429222, states[0] = 7.100628, states[40]= 0.007159
Saving checkpoint... 
Iteration: 1106139817, states[0] = -48.987570, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1115919984, states[0] = 12.079325, states[40]= 0.007875
Saving checkpoint... 
Iteration: 1125602542, states[0] = -1.084017, states[40]= 0.005783
Saving checkpoint... 
Iteration: 1135259375, states[0] = 6.574161, states[40]= 0.007090
Saving checkpoint... 
Iteration: 1145030296, states[0] = -87.791029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154574873, states[0] = 16.621180, states[40]= 0.009387
Saving checkpoint... 
Iteration: 1164244782, states[0] = 14.314031, states[40]= 0.008380
Saving checkpoint... 
Iteration: 1173679376, states[0] = -87.732219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183097111, states[0] = -1.407206, states[40]= 0.005708
Saving checkpoint... 
Iteration: 1192495497, states[0] = -87.388522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202034121, states[0] = -87.821966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211610317, states[0] = -22.457470, states[40]= 0.001018
Saving checkpoint... 
Iteration: 1221067414, states[0] = 17.032724, states[40]= 0.009686
Saving checkpoint... 
Iteration: 1230566886, states[0] = 16.819032, states[40]= 0.009524
Saving checkpoint... 
Iteration: 1234945416, states[0] = -28.249033, states[40]= 0.000614
Saving checkpoint... 
Iteration: 1239829595, states[0] = -87.643066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240520020, states[0] = -87.788354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248368158, states[0] = -87.837547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249123119, states[0] = -45.590545, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1256646392, states[0] = -83.135130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257152293, states[0] = -86.835912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266943680, states[0] = -30.295790, states[40]= 0.000504
Saving checkpoint... 
Iteration: 1276835684, states[0] = -87.731874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286754524, states[0] = -2.568964, states[40]= 0.005423
Saving checkpoint... 
Iteration: 1296503310, states[0] = -87.745298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306264618, states[0] = -18.316456, states[40]= 0.001485
Saving checkpoint... 
Iteration: 1316018336, states[0] = -87.808054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325904709, states[0] = 8.239019, states[40]= 0.007308
Saving checkpoint... 
Iteration: 1335672237, states[0] = -87.770200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345521535, states[0] = -87.827070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355433843, states[0] = -28.913256, states[40]= 0.000577
Saving checkpoint... 
Iteration: 1365150080, states[0] = -87.636391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374890266, states[0] = 14.381138, states[40]= 0.008401
Saving checkpoint... 
Iteration: 1384675886, states[0] = -87.800485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394428329, states[0] = -26.646322, states[40]= 0.000709
Saving checkpoint... 
Iteration: 1404002463, states[0] = -87.783725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413506263, states[0] = -87.800145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422766840, states[0] = -37.805653, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1432175631, states[0] = -87.814903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441567518, states[0] = 2.141763, states[40]= 0.006431
Saving checkpoint... 
Iteration: 1450813050, states[0] = -87.699702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460241201, states[0] = -7.262040, states[40]= 0.004091
Saving checkpoint... 
Iteration: 1469555292, states[0] = 9.443910, states[40]= 0.007469
Saving checkpoint... 
Iteration: 1478912943, states[0] = -16.776213, states[40]= 0.001724
Saving checkpoint... 
Iteration: 1487851680, states[0] = -9.374863, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1497379727, states[0] = 13.374330, states[40]= 0.008139
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.731471
 - CaMKt in component CaMK (millimolar): 0.042443
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 6.972630
 - nass in component intracellular_ions (millimolar): 6.972779
 - ki in component intracellular_ions (millimolar): 144.947550
 - kss in component intracellular_ions (millimolar): 144.947518
 - cansr in component intracellular_ions (millimolar): 1.620296
 - cajsr in component intracellular_ions (millimolar): 1.187953
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007453
 - hf in component INa (dimensionless): 0.693022
 - hs in component INa (dimensionless): 0.692790
 - j in component INa (dimensionless): 0.682562
 - hsp in component INa (dimensionless): 0.448025
 - jp in component INa (dimensionless): 0.656479
 - mL in component INaL (dimensionless): 0.000194
 - hL in component INaL (dimensionless): 0.295098
 - hLp in component INaL (dimensionless): 0.137476
 - a in component Ito (dimensionless): 0.001011
 - iF in component Ito (dimensionless): 0.999542
 - iS in component Ito (dimensionless): 0.176339
 - ap in component Ito (dimensionless): 0.000515
 - iFp in component Ito (dimensionless): 0.999542
 - iSp in component Ito (dimensionless): 0.213599
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804756
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.967056
 - jca in component ICaL (dimensionless): 0.948108
 - ffp in component ICaL (dimensionless): 0.999867
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009464
 - xrf in component IKr (dimensionless): 0.028006
 - xrs in component IKr (dimensionless): 0.785560
 - xs1 in component IKs (dimensionless): 0.458444
 - xs2 in component IKs (dimensionless): 0.001155
 - xk1 in component IK1 (dimensionless): 0.996803
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:30:09 (1166): called boinc_finish(0)

</stderr_txt>
]]>


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