𝕏

Task 55517995

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_15-conf_421_1
Workunit 26360103
Created 1 Jul 2024, 14:53:58 UTC
Sent 1 Jul 2024, 17:07:23 UTC
Report deadline 4 Jul 2024, 17:07:23 UTC
Received 2 Jul 2024, 8:07:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 225785
Run time 1 hours 44 min 33 sec
CPU time 1 hours 35 min 19 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.23 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.57 MB
Peak swap size 5.27 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_15-conf_421.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_15-conf_421_1_r88505108_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_15-conf_421_1_r88505108_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 100.723711
     * GNaL_b in INaL: 0.005901
     * Gto_b in Ito: 0.084746
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.026712
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.164617
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.458818
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031822
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9240220, states[0] = -94.747890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17206398, states[0] = -94.564573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26798598, states[0] = -94.776791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35187005, states[0] = -92.025783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44920858, states[0] = -94.870812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54527127, states[0] = 26.347396, states[40]= 0.001573
Saving checkpoint... 
Iteration: 63921419, states[0] = -94.864355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71693657, states[0] = -93.925576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81467840, states[0] = -94.878303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89576589, states[0] = 8.158457, states[40]= 0.004661
Saving checkpoint... 
Iteration: 99186161, states[0] = -90.001047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106915993, states[0] = -94.856156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117176900, states[0] = -76.074293, states[40]= 0.000002
Saving checkpoint... 
Iteration: 127037534, states[0] = 23.358454, states[40]= 0.001942
Saving checkpoint... 
Iteration: 134459034, states[0] = -94.871945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144229653, states[0] = -94.573418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152210064, states[0] = -94.496252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161756011, states[0] = -94.652970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171543522, states[0] = 21.351050, states[40]= 0.002310
Saving checkpoint... 
Iteration: 179856994, states[0] = -94.814518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187834731, states[0] = -94.792077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197600587, states[0] = -6.014907, states[40]= 0.003651
Saving checkpoint... 
Iteration: 206129178, states[0] = -29.604534, states[40]= 0.001373
Saving checkpoint... 
Iteration: 215701391, states[0] = -94.407068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225446807, states[0] = -94.866616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234691136, states[0] = -93.174321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244206047, states[0] = -94.469426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253498052, states[0] = -94.880706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262666843, states[0] = -63.333396, states[40]= 0.000013
Saving checkpoint... 
Iteration: 271765159, states[0] = -94.675094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280840128, states[0] = -94.797440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289710406, states[0] = -94.496888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297657726, states[0] = -54.312482, states[40]= 0.000059
Saving checkpoint... 
Iteration: 307210895, states[0] = -94.499260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315574960, states[0] = 8.991501, states[40]= 0.004594
Saving checkpoint... 
Iteration: 323533815, states[0] = 24.554183, states[40]= 0.001766
Saving checkpoint... 
Iteration: 332617571, states[0] = -20.167416, states[40]= 0.001516
Saving checkpoint... 
Iteration: 340703106, states[0] = -94.436824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349944888, states[0] = -94.865376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359585170, states[0] = 3.884049, states[40]= 0.004877
Saving checkpoint... 
Iteration: 367397945, states[0] = -94.843378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375382126, states[0] = -94.833273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384530880, states[0] = 25.429810, states[40]= 0.001658
Saving checkpoint... 
Iteration: 393922027, states[0] = -94.855818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401803141, states[0] = -94.748781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410383044, states[0] = -94.833766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419488634, states[0] = -94.877955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428667103, states[0] = -63.607356, states[40]= 0.000013
Saving checkpoint... 
Iteration: 436448438, states[0] = -94.866310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444766274, states[0] = -94.677044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454495156, states[0] = -94.879280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464329478, states[0] = -94.784723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474162653, states[0] = -59.052033, states[40]= 0.000027
Saving checkpoint... 
Iteration: 483963978, states[0] = -94.871180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493606211, states[0] = -10.532830, states[40]= 0.002603
Saving checkpoint... 
Iteration: 503433140, states[0] = -94.860226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513253158, states[0] = -94.643536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522947358, states[0] = -94.865592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532857015, states[0] = -94.812916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542883704, states[0] = -94.833700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552112747, states[0] = -16.097543, states[40]= 0.001698
Saving checkpoint... 
Iteration: 561938495, states[0] = -94.862141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571637789, states[0] = -36.634760, states[40]= 0.000717
Saving checkpoint... 
Iteration: 581233881, states[0] = -94.585278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590961364, states[0] = -94.869970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600666421, states[0] = -62.882940, states[40]= 0.000014
Saving checkpoint... 
Iteration: 610439218, states[0] = -94.862233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620253510, states[0] = -94.644071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629945319, states[0] = -94.864443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639444254, states[0] = -94.864018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649061740, states[0] = 14.646440, states[40]= 0.003719
Saving checkpoint... 
Iteration: 658482484, states[0] = -94.875553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668319327, states[0] = -94.771172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677876787, states[0] = -94.828312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687687292, states[0] = -90.866238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697411890, states[0] = -94.849727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705583542, states[0] = 4.755074, states[40]= 0.004867
Saving checkpoint... 
Iteration: 713980490, states[0] = -94.874839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722428717, states[0] = -94.857516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731237740, states[0] = -94.597220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740887233, states[0] = -94.835281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750030583, states[0] = 25.515340, states[40]= 0.001649
Saving checkpoint... 
Iteration: 758106989, states[0] = -11.185774, states[40]= 0.002464
Saving checkpoint... 
Iteration: 767676174, states[0] = -74.799524, states[40]= 0.000002
Saving checkpoint... 
Iteration: 776759654, states[0] = -94.659553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784769571, states[0] = -94.683349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794086149, states[0] = 3.349346, states[40]= 0.004874
Saving checkpoint... 
Iteration: 801808385, states[0] = -94.755260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810322386, states[0] = -94.774607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819548624, states[0] = 19.563294, states[40]= 0.002676
Saving checkpoint... 
Iteration: 828658989, states[0] = -55.504827, states[40]= 0.000049
Saving checkpoint... 
Iteration: 837047933, states[0] = 19.809503, states[40]= 0.002624
Saving checkpoint... 
Iteration: 845279075, states[0] = -94.703650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852692453, states[0] = -93.570534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862163955, states[0] = -60.346765, states[40]= 0.000022
Saving checkpoint... 
Iteration: 870394413, states[0] = -94.839309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879645092, states[0] = -42.834326, states[40]= 0.000326
Saving checkpoint... 
Iteration: 888730820, states[0] = -94.573789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898012421, states[0] = 28.333083, states[40]= 0.021959
Saving checkpoint... 
Iteration: 907220784, states[0] = -94.537851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915249283, states[0] = -94.631209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924307567, states[0] = -94.753557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933765707, states[0] = -94.673785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941905782, states[0] = -94.845565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950051861, states[0] = 18.395571, states[40]= 0.002927
Saving checkpoint... 
Iteration: 959606005, states[0] = -10.359094, states[40]= 0.002641
Saving checkpoint... 
Iteration: 968910624, states[0] = -94.848022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976991082, states[0] = -94.876351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986256276, states[0] = -94.650013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994334460, states[0] = -94.788432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004138804, states[0] = -37.477989, states[40]= 0.000649
Saving checkpoint... 
Iteration: 1012048836, states[0] = 19.487785, states[40]= 0.002692
Saving checkpoint... 
Iteration: 1021351096, states[0] = -94.805566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029363406, states[0] = -94.816501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038721479, states[0] = -94.539933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046562489, states[0] = 14.348533, states[40]= 0.003778
Saving checkpoint... 
Iteration: 1055935961, states[0] = -94.859223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065304390, states[0] = -94.748145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073268122, states[0] = -94.678895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082433486, states[0] = -94.858118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090557523, states[0] = 16.286561, states[40]= 0.003383
Saving checkpoint... 
Iteration: 1099937212, states[0] = -94.859548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109297863, states[0] = -94.737446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117358608, states[0] = -94.812049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126820044, states[0] = -94.770329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134651583, states[0] = -48.619682, states[40]= 0.000143
Saving checkpoint... 
Iteration: 1143962003, states[0] = -94.868018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153200446, states[0] = -94.379775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162548924, states[0] = 19.456500, states[40]= 0.002699
Saving checkpoint... 
Iteration: 1171951253, states[0] = -94.864429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179799584, states[0] = -94.740019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189403208, states[0] = -94.843189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198685980, states[0] = -89.547695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206518565, states[0] = 28.078341, states[40]= 0.003788
Saving checkpoint... 
Iteration: 1216173003, states[0] = -70.463097, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1224058956, states[0] = 15.736972, states[40]= 0.003498
Saving checkpoint... 
Iteration: 1233731081, states[0] = -94.573319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243021763, states[0] = 27.611824, states[40]= 0.002164
Saving checkpoint... 
Iteration: 1252156404, states[0] = -53.066161, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1259050832, states[0] = 18.769900, states[40]= 0.002846
Saving checkpoint... 
Iteration: 1267369854, states[0] = -94.820786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275044549, states[0] = 21.000306, states[40]= 0.002381
Saving checkpoint... 
Iteration: 1284063041, states[0] = 14.127429, states[40]= 0.003820
Saving checkpoint... 
Iteration: 1292016818, states[0] = 28.240726, states[40]= 0.005841
Saving checkpoint... 
Iteration: 1301326218, states[0] = -94.777510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309153408, states[0] = -50.288634, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1318344569, states[0] = -94.798000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327802093, states[0] = -94.743500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336757353, states[0] = -94.651451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344804618, states[0] = -94.747408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354351673, states[0] = -94.804815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363693685, states[0] = -93.833031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372064800, states[0] = 13.413511, states[40]= 0.003953
Saving checkpoint... 
Iteration: 1381601603, states[0] = -6.790511, states[40]= 0.003471
Saving checkpoint... 
Iteration: 1390912234, states[0] = -94.847206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398767209, states[0] = -94.675498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408122898, states[0] = -24.525360, states[40]= 0.001581
Saving checkpoint... 
Iteration: 1415816570, states[0] = -94.764545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425121578, states[0] = -23.454777, states[40]= 0.001568
Saving checkpoint... 
Iteration: 1432968721, states[0] = -94.868883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442390546, states[0] = -94.834685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450190158, states[0] = -92.759566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459538145, states[0] = 23.173162, states[40]= 0.001982
Saving checkpoint... 
Iteration: 1467573074, states[0] = 9.857004, states[40]= 0.004496
Saving checkpoint... 
Iteration: 1477210406, states[0] = -94.492171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486685258, states[0] = -88.695150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494552813, states[0] = 18.047924, states[40]= 0.003003
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.752118
 - CaMKt in component CaMK (millimolar): 0.013101
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.664802
 - nass in component intracellular_ions (millimolar): 6.664896
 - ki in component intracellular_ions (millimolar): 145.217191
 - kss in component intracellular_ions (millimolar): 145.217172
 - cansr in component intracellular_ions (millimolar): 1.665953
 - cajsr in component intracellular_ions (millimolar): 1.622450
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003674
 - hf in component INa (dimensionless): 0.877378
 - hs in component INa (dimensionless): 0.877370
 - j in component INa (dimensionless): 0.877316
 - hsp in component INa (dimensionless): 0.720885
 - jp in component INa (dimensionless): 0.877280
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.698824
 - hLp in component INaL (dimensionless): 0.428375
 - a in component Ito (dimensionless): 0.000630
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.595373
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.663833
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.906451
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999780
 - jca in component ICaL (dimensionless): 0.999964
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003051
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.385545
 - xs1 in component IKs (dimensionless): 0.285593
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997376
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:21:34 (12500): called boinc_finish(0)

</stderr_txt>
]]>


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