𝕏

Task 55516231

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_420_0
Workunit 26359223
Created 1 Jul 2024, 14:53:06 UTC
Sent 1 Jul 2024, 16:55:39 UTC
Report deadline 4 Jul 2024, 16:55:39 UTC
Received 4 Jul 2024, 15:58:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224330
Run time 2 hours 5 min 9 sec
CPU time 1 hours 52 min 37 sec
Validate state Valid
Credit 38.24
Device peak FLOPS 3.08 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.87 MB
Peak swap size 6.25 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_420.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_420_0_r1510229666_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_420_0_r1510229666_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.164802
     * GNaL_b in INaL: 0.005793
     * Gto_b in Ito: 0.080833
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032031
     * GKs_b in IKs: 0.001926
     * GK1_b in IK1: 0.167649
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.199019
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029174
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5724966, states[0] = -94.160490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16525731, states[0] = -94.047679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23860400, states[0] = -94.012676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28485121, states[0] = -93.983301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42149587, states[0] = -32.169526, states[40]= 0.001880
Saving checkpoint... 
Iteration: 54598444, states[0] = -93.992293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65675176, states[0] = -93.973575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75930161, states[0] = -93.968015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84953574, states[0] = -93.995751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97825188, states[0] = -93.969437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110392055, states[0] = -93.879357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121435176, states[0] = -93.978433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131390974, states[0] = -93.979716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142517933, states[0] = -93.969116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153854685, states[0] = -93.968746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162541948, states[0] = -93.976948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174783368, states[0] = -93.999785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186822536, states[0] = -93.999266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198548220, states[0] = -93.978635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210100634, states[0] = 3.792390, states[40]= 0.003377
Saving checkpoint... 
Iteration: 221487557, states[0] = -93.976754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233242398, states[0] = -93.984349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244505543, states[0] = -93.964043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255958130, states[0] = -93.966751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266485267, states[0] = -93.954699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277081397, states[0] = -93.990259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287908146, states[0] = -93.967501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299233789, states[0] = -93.984495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310139790, states[0] = -24.615007, states[40]= 0.002290
Saving checkpoint... 
Iteration: 320852336, states[0] = -93.998302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331687508, states[0] = -93.971635, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_420.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_420_0_r1510229666_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_420_0_r1510229666_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.164802
     * GNaL_b in INaL: 0.005793
     * Gto_b in Ito: 0.080833
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032031
     * GKs_b in IKs: 0.001926
     * GK1_b in IK1: 0.167649
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.199019
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029174
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 331687508
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.971635 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 339626324, states[0] = -93.972987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361919302, states[0] = -93.967134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378492853, states[0] = -93.958119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392063650, states[0] = 19.709068, states[40]= 0.000757
Saving checkpoint... 
Iteration: 412978415, states[0] = -93.993928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433058949, states[0] = -93.990759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447218582, states[0] = -93.984680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467200650, states[0] = -93.985280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480581208, states[0] = -93.985592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499524594, states[0] = -93.975100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518167323, states[0] = -45.548706, states[40]= 0.000437
Saving checkpoint... 
Iteration: 536350547, states[0] = -93.815524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554106570, states[0] = 0.496700, states[40]= 0.003652
Saving checkpoint... 
Iteration: 571459500, states[0] = -93.976684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588269241, states[0] = -93.584459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604093382, states[0] = 7.399145, states[40]= 0.002809
Saving checkpoint... 
Iteration: 616745961, states[0] = -93.998669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627637024, states[0] = -93.972043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638644221, states[0] = -93.993967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649964468, states[0] = -93.965697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664666924, states[0] = -93.995721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677894149, states[0] = -93.966798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690468053, states[0] = -93.944242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702339240, states[0] = -93.793051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706720393, states[0] = -93.998012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717736588, states[0] = -93.969667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725989576, states[0] = -93.965116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738480035, states[0] = -93.950854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747002802, states[0] = -93.992189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759142853, states[0] = -93.986726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771004504, states[0] = -93.992065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782779891, states[0] = -93.998346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794507387, states[0] = -93.963474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806162848, states[0] = -42.029699, states[40]= 0.000691
Saving checkpoint... 
Iteration: 817621315, states[0] = -93.971947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829200293, states[0] = -93.984418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840607967, states[0] = -93.989224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852105759, states[0] = 0.970920, states[40]= 0.003631
Saving checkpoint... 
Iteration: 863535645, states[0] = -93.973934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871715375, states[0] = -93.969734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883473436, states[0] = -93.975542, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_420.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_420_0_r1510229666_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_420_0_r1510229666_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.164802
     * GNaL_b in INaL: 0.005793
     * Gto_b in Ito: 0.080833
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032031
     * GKs_b in IKs: 0.001926
     * GK1_b in IK1: 0.167649
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.199019
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029174
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 883473436
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.975542 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 894909503, states[0] = -93.995235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912992569, states[0] = -93.992181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928802434, states[0] = -93.997794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946496526, states[0] = -93.958438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960153841, states[0] = -35.122703, states[40]= 0.001508
Saving checkpoint... 
Iteration: 980229809, states[0] = -93.367677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992923331, states[0] = -93.994530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009247523, states[0] = -93.982296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025684215, states[0] = -93.970027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038561888, states[0] = -93.980092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051201384, states[0] = -93.983842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068551755, states[0] = -93.977486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085429393, states[0] = -93.976298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102067884, states[0] = 18.113512, states[40]= 0.000947
Saving checkpoint... 
Iteration: 1119049647, states[0] = -93.989466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130509277, states[0] = -93.963425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141025065, states[0] = -93.990374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155638052, states[0] = -93.970742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170049246, states[0] = 24.815898, states[40]= 0.000336
Saving checkpoint... 
Iteration: 1184580197, states[0] = -93.983696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197701016, states[0] = -93.969249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211133014, states[0] = -93.986009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224351701, states[0] = -93.815961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237329940, states[0] = -93.978973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248325069, states[0] = -93.760289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257713455, states[0] = -93.968840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267982419, states[0] = -93.963916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275430769, states[0] = -93.975799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287740820, states[0] = -93.968201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299674893, states[0] = -93.969568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307677840, states[0] = -93.969484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319882569, states[0] = -93.965445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332144107, states[0] = -27.833223, states[40]= 0.002378
Saving checkpoint... 
Iteration: 1344925525, states[0] = -93.993605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354359297, states[0] = -93.828984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361050790, states[0] = -93.988837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372357479, states[0] = -93.825838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383677677, states[0] = -93.969303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390079011, states[0] = 13.706696, states[40]= 0.001625
Saving checkpoint... 
Iteration: 1397672047, states[0] = -93.969393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409316363, states[0] = -93.978999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420809636, states[0] = -93.996508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432471724, states[0] = -93.944591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443632205, states[0] = -93.970180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454791340, states[0] = -93.996645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465386503, states[0] = -93.976652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472647836, states[0] = -93.992283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483224250, states[0] = -93.981973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493831028, states[0] = -93.965950, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.839050
 - CaMKt in component CaMK (millimolar): 0.002087
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.756264
 - nass in component intracellular_ions (millimolar): 6.756388
 - ki in component intracellular_ions (millimolar): 145.101148
 - kss in component intracellular_ions (millimolar): 145.101138
 - cansr in component intracellular_ions (millimolar): 1.837497
 - cajsr in component intracellular_ions (millimolar): 1.837327
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004028
 - hf in component INa (dimensionless): 0.860301
 - hs in component INa (dimensionless): 0.860302
 - j in component INa (dimensionless): 0.860305
 - hsp in component INa (dimensionless): 0.689777
 - jp in component INa (dimensionless): 0.860308
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.700287
 - hLp in component INaL (dimensionless): 0.504647
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.991437
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.996571
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996464
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005320
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008072
 - xs1 in component IKs (dimensionless): 0.041289
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997603
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:58:29 (11332): called boinc_finish(0)

</stderr_txt>
]]>


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