𝕏

Task 55511156

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_2000-conf_315_1
Workunit 26356692
Created 1 Jul 2024, 14:50:36 UTC
Sent 1 Jul 2024, 16:28:39 UTC
Report deadline 4 Jul 2024, 16:28:39 UTC
Received 3 Jul 2024, 7:11:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 56 min 13 sec
CPU time 1 hours 30 min 1 sec
Validate state Valid
Credit 42.27
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_2000-conf_315.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_2000-conf_315_1_r1027684731_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_MID_2000-conf_315_1_r1027684731_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.465139
     * GNaL_b in INaL: 0.005654
     * Gto_b in Ito: 0.086922
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031408
     * GKs_b in IKs: 0.001889
     * GK1_b in IK1: 0.160927
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.279187
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030552
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9801691, states[0] = -94.269713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 18209236, states[0] = -26.225935, states[40]= 0.008772
Saving checkpoint... 
Iteration: 25636354, states[0] = -94.252922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33768859, states[0] = -94.272766, states[40]= 0.000001
Saving checkpoint... 
Iteration: 42395577, states[0] = -94.090149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50628981, states[0] = -94.286953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 58075265, states[0] = 23.851196, states[40]= 0.000003
Saving checkpoint... 
Iteration: 66071195, states[0] = 25.093272, states[40]= 0.000002
Saving checkpoint... 
Iteration: 74578341, states[0] = -94.299668, states[40]= 0.000001
Saving checkpoint... 
Iteration: 83936351, states[0] = -94.317272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 91372983, states[0] = -94.097971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99979469, states[0] = -94.321928, states[40]= 0.000001
Saving checkpoint... 
Iteration: 108910465, states[0] = -94.328801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 118407358, states[0] = -94.182305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 126886915, states[0] = -94.333871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 136604425, states[0] = -94.328280, states[40]= 0.000001
Saving checkpoint... 
Iteration: 145096228, states[0] = 14.772452, states[40]= 0.000046
Saving checkpoint... 
Iteration: 154059191, states[0] = 28.385627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162187128, states[0] = -29.515626, states[40]= 0.008527
Saving checkpoint... 
Iteration: 171411747, states[0] = -94.196143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179934174, states[0] = -94.334679, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188235460, states[0] = -62.412723, states[40]= 0.000182
Saving checkpoint... 
Iteration: 197542873, states[0] = -94.312529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 206115227, states[0] = 6.770657, states[40]= 0.000271
Saving checkpoint... 
Iteration: 216074773, states[0] = 23.027813, states[40]= 0.000004
Saving checkpoint... 
Iteration: 224438724, states[0] = -94.234459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 232997762, states[0] = -94.330124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 243141816, states[0] = -6.200880, states[40]= 0.001298
Saving checkpoint... 
Iteration: 251161325, states[0] = -18.186030, states[40]= 0.002681
Saving checkpoint... 
Iteration: 260009737, states[0] = 29.240900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268864918, states[0] = -94.336677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278358341, states[0] = -94.076189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286829516, states[0] = -94.337648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 295717203, states[0] = -94.338872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 305063801, states[0] = 26.862873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 314789601, states[0] = -94.337980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 323106374, states[0] = 10.482405, states[40]= 0.000126
Saving checkpoint... 
Iteration: 331711927, states[0] = -94.337484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341176858, states[0] = -25.291169, states[40]= 0.008348
Saving checkpoint... 
Iteration: 349770945, states[0] = -94.337109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 359856214, states[0] = -94.333934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367936361, states[0] = -94.329341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376621633, states[0] = -94.328214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 385014535, states[0] = 31.706791, states[40]= -0.000000
Saving checkpoint... 
Iteration: 392614675, states[0] = -94.326480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 400456451, states[0] = -94.248445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 410516733, states[0] = -94.293567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 418973867, states[0] = -94.325253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427489923, states[0] = -94.276215, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436094599, states[0] = 15.319698, states[40]= 0.000040
Saving checkpoint... 
Iteration: 445098773, states[0] = 13.620528, states[40]= 0.000061
Saving checkpoint... 
Iteration: 453514023, states[0] = -94.290533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 462229866, states[0] = -57.859992, states[40]= 0.000358
Saving checkpoint... 
Iteration: 471538125, states[0] = -94.301685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 480332129, states[0] = -93.979434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 488918314, states[0] = -94.326039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 496986078, states[0] = -94.321694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505590454, states[0] = -94.317457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514209833, states[0] = -42.786678, states[40]= 0.002652
Saving checkpoint... 
Iteration: 522390017, states[0] = -94.145788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531370078, states[0] = -94.099347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 539559649, states[0] = -94.307455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 548834884, states[0] = -94.328080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556986108, states[0] = -94.319532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564859194, states[0] = -94.326427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574009115, states[0] = 28.786796, states[40]= -0.000000
Saving checkpoint... 
Iteration: 582854946, states[0] = -94.325977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 592009443, states[0] = 29.032290, states[40]= -0.000000
Saving checkpoint... 
Iteration: 600792803, states[0] = -94.327638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 609143587, states[0] = -7.264485, states[40]= 0.001339
Saving checkpoint... 
Iteration: 617149541, states[0] = -10.991547, states[40]= 0.001425
Saving checkpoint... 
Iteration: 625881793, states[0] = -94.323109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636816884, states[0] = -94.325606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 646197505, states[0] = -35.057233, states[40]= 0.005901
Saving checkpoint... 
Iteration: 655717719, states[0] = -94.325991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662634323, states[0] = -94.319786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671680975, states[0] = -94.323906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680494727, states[0] = -94.270442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689054914, states[0] = 29.593794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697339457, states[0] = -93.999211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 704515976, states[0] = -94.282554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 712892583, states[0] = -94.319416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721584157, states[0] = -94.308139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730225927, states[0] = -54.690250, states[40]= 0.000565
Saving checkpoint... 
Iteration: 740073564, states[0] = 23.466208, states[40]= 0.000004
Saving checkpoint... 
Iteration: 748158426, states[0] = -16.533549, states[40]= 0.002033
Saving checkpoint... 
Iteration: 756058262, states[0] = 28.619137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764770704, states[0] = -94.322206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773681503, states[0] = -94.320291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 781746053, states[0] = -94.321798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 789051757, states[0] = 30.447214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796382522, states[0] = -94.119684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 805275873, states[0] = -93.654972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814589863, states[0] = -94.306218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822980238, states[0] = -94.310354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831115822, states[0] = 6.500772, states[40]= 0.000284
Saving checkpoint... 
Iteration: 839848503, states[0] = -94.317053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 850132644, states[0] = -1.195311, states[40]= 0.000915
Saving checkpoint... 
Iteration: 858169713, states[0] = -22.258174, states[40]= 0.005991
Saving checkpoint... 
Iteration: 866738804, states[0] = -94.318714, states[40]= 0.000001
Saving checkpoint... 
Iteration: 876106096, states[0] = 10.608109, states[40]= 0.000122
Saving checkpoint... 
Iteration: 885089380, states[0] = 17.419733, states[40]= 0.000023
Saving checkpoint... 
Iteration: 893516321, states[0] = -94.275944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 901303646, states[0] = -93.831210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909551226, states[0] = -94.291160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 918218973, states[0] = -49.360000, states[40]= 0.001174
Saving checkpoint... 
Iteration: 926568613, states[0] = -94.296421, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934033965, states[0] = 33.563250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942344815, states[0] = -94.009136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949749475, states[0] = -94.315746, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957222697, states[0] = -52.176506, states[40]= 0.000803
Saving checkpoint... 
Iteration: 965366887, states[0] = -94.075160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 973115387, states[0] = 6.690700, states[40]= 0.000274
Saving checkpoint... 
Iteration: 981617641, states[0] = -94.305811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 989676407, states[0] = -94.312192, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998221129, states[0] = -50.979108, states[40]= 0.000946
Saving checkpoint... 
Iteration: 1006191796, states[0] = -31.994717, states[40]= 0.007469
Saving checkpoint... 
Iteration: 1014982693, states[0] = -94.303294, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1023229269, states[0] = -57.322906, states[40]= 0.000386
Saving checkpoint... 
Iteration: 1031784265, states[0] = -94.312367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1039661071, states[0] = -94.309203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1047432438, states[0] = -94.197200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1055379246, states[0] = -94.102729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1063250549, states[0] = -82.080600, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1073009809, states[0] = 29.297756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081711166, states[0] = -94.310527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092009574, states[0] = 29.131668, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1099804951, states[0] = -94.309380, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1107868980, states[0] = -94.306459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1116398659, states[0] = -94.141276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124739680, states[0] = -94.309449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1132849188, states[0] = -94.306502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1141877715, states[0] = -94.304813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150204759, states[0] = -39.381932, states[40]= 0.003863
Saving checkpoint... 
Iteration: 1158707888, states[0] = -94.307682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1168848219, states[0] = -94.305262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1177479231, states[0] = -94.241065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1186674348, states[0] = -94.304991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195274597, states[0] = -93.628773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203513952, states[0] = -94.263486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1212025893, states[0] = 33.709629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220835991, states[0] = -94.303915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230359106, states[0] = -94.043815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1238702552, states[0] = -94.304614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1247173240, states[0] = -23.749421, states[40]= 0.007348
Saving checkpoint... 
Iteration: 1255820134, states[0] = -94.303275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1264630783, states[0] = -94.297678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272638136, states[0] = -94.298379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1281582838, states[0] = -94.287673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1291735784, states[0] = -94.303432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299151792, states[0] = -12.395187, states[40]= 0.001467
Saving checkpoint... 
Iteration: 1307171711, states[0] = -23.101976, states[40]= 0.006793
Saving checkpoint... 
Iteration: 1315216086, states[0] = -47.189548, states[40]= 0.001552
Saving checkpoint... 
Iteration: 1323421260, states[0] = -94.171629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332771544, states[0] = -94.301801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1341346419, states[0] = -93.999986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349620539, states[0] = -94.293070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358397520, states[0] = -94.130352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1366585866, states[0] = -94.285386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1374854784, states[0] = -94.297552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383932381, states[0] = -94.293088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391542306, states[0] = -94.270329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1399191199, states[0] = -31.676056, states[40]= 0.007615
Saving checkpoint... 
Iteration: 1408277346, states[0] = -93.644428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417085708, states[0] = 18.875275, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1425268856, states[0] = -93.536322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433833990, states[0] = -94.296345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1441952159, states[0] = -94.289828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450616473, states[0] = -94.288768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459388505, states[0] = -94.108576, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1468133245, states[0] = -1.477392, states[40]= 0.000942
Saving checkpoint... 
Iteration: 1477479364, states[0] = -94.230336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1485675459, states[0] = -94.294320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494742311, states[0] = -94.296181, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.160755
 - CaMKt in component CaMK (millimolar): 0.010026
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 8.171875
 - nass in component intracellular_ions (millimolar): 8.172053
 - ki in component intracellular_ions (millimolar): 143.365845
 - kss in component intracellular_ions (millimolar): 143.365821
 - cansr in component intracellular_ions (millimolar): 2.129922
 - cajsr in component intracellular_ions (millimolar): 2.132465
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.003900
 - hf in component INa (dimensionless): 0.866534
 - hs in component INa (dimensionless): 0.866537
 - j in component INa (dimensionless): 0.866551
 - hsp in component INa (dimensionless): 0.700986
 - jp in component INa (dimensionless): 0.866559
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708915
 - hLp in component INaL (dimensionless): 0.490039
 - a in component Ito (dimensionless): 0.000655
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.869955
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.912298
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.959300
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005390
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.126316
 - xs1 in component IKs (dimensionless): 0.169418
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997525
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
07:11:05 (52831): called boinc_finish(0)

</stderr_txt>
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