𝕏

Task 55510652

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_215_0
Workunit 26356441
Created 1 Jul 2024, 14:50:26 UTC
Sent 1 Jul 2024, 16:24:46 UTC
Report deadline 4 Jul 2024, 16:24:46 UTC
Received 3 Jul 2024, 5:08:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 40 min 44 sec
CPU time 2 hours 17 min 36 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.20 MB
Peak swap size 6.20 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_215.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_215_0_r1239599857_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_215_0_r1239599857_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 100.020766
     * GNaL_b in INaL: 0.005785
     * Gto_b in Ito: 0.085281
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032249
     * GKs_b in IKs: 0.001939
     * GK1_b in IK1: 0.162074
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.773826
     * GKb_b in IKb: 0.003811
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029410
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7902288, states[0] = -86.826379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 16078994, states[0] = 18.637165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 24966817, states[0] = -86.898216, states[40]= 0.000002
Saving checkpoint... 
Iteration: 33167817, states[0] = -38.451650, states[40]= 0.000291
Saving checkpoint... 
Iteration: 41150826, states[0] = -26.148102, states[40]= 0.000458
Saving checkpoint... 
Iteration: 49419001, states[0] = -86.913852, states[40]= 0.000002
Saving checkpoint... 
Iteration: 57937925, states[0] = -86.939572, states[40]= 0.000002
Saving checkpoint... 
Iteration: 66336447, states[0] = -86.824845, states[40]= 0.000002
Saving checkpoint... 
Iteration: 74896121, states[0] = -86.921823, states[40]= 0.000002
Saving checkpoint... 
Iteration: 83170073, states[0] = -48.753598, states[40]= 0.000124
Saving checkpoint... 
Iteration: 91542794, states[0] = 29.064625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100409590, states[0] = -86.948943, states[40]= 0.000002
Saving checkpoint... 
Iteration: 109136442, states[0] = -20.182451, states[40]= 0.000266
Saving checkpoint... 
Iteration: 117997444, states[0] = -87.003361, states[40]= 0.000002
Saving checkpoint... 
Iteration: 126252935, states[0] = -86.556314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134897089, states[0] = -86.943993, states[40]= 0.000002
Saving checkpoint... 
Iteration: 143046223, states[0] = 27.969072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151346314, states[0] = -86.874516, states[40]= 0.000002
Saving checkpoint... 
Iteration: 159174002, states[0] = -55.405994, states[40]= 0.000058
Saving checkpoint... 
Iteration: 167554278, states[0] = 25.431135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175566510, states[0] = 20.906493, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183798404, states[0] = -86.756370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192379706, states[0] = -86.925005, states[40]= 0.000002
Saving checkpoint... 
Iteration: 201260476, states[0] = -86.598925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209355411, states[0] = -86.889397, states[40]= 0.000002
Saving checkpoint... 
Iteration: 217695929, states[0] = -84.220808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 226142118, states[0] = -25.507334, states[40]= 0.000469
Saving checkpoint... 
Iteration: 234575144, states[0] = 17.304543, states[40]= 0.000003
Saving checkpoint... 
Iteration: 242963309, states[0] = -86.990218, states[40]= 0.000002
Saving checkpoint... 
Iteration: 250885849, states[0] = -86.929615, states[40]= 0.000002
Saving checkpoint... 
Iteration: 259661196, states[0] = -42.267562, states[40]= 0.000263
Saving checkpoint... 
Iteration: 268082447, states[0] = 14.055152, states[40]= 0.000008
Saving checkpoint... 
Iteration: 276021623, states[0] = 31.519270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283457007, states[0] = -86.984711, states[40]= 0.000002
Saving checkpoint... 
Iteration: 291539322, states[0] = 29.683764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300436064, states[0] = -86.971357, states[40]= 0.000002
Saving checkpoint... 
Iteration: 308648003, states[0] = -30.326211, states[40]= 0.000551
Saving checkpoint... 
Iteration: 318082587, states[0] = 13.990997, states[40]= 0.000008
Saving checkpoint... 
Iteration: 326943638, states[0] = -86.974560, states[40]= 0.000002
Saving checkpoint... 
Iteration: 335104574, states[0] = 3.016126, states[40]= 0.000077
Saving checkpoint... 
Iteration: 343417907, states[0] = -86.955419, states[40]= 0.000002
Saving checkpoint... 
Iteration: 352187828, states[0] = -74.532410, states[40]= 0.000004
Saving checkpoint... 
Iteration: 360680857, states[0] = -64.041714, states[40]= 0.000018
Saving checkpoint... 
Iteration: 368940099, states[0] = -86.969814, states[40]= 0.000002
Saving checkpoint... 
Iteration: 377496511, states[0] = -86.995603, states[40]= 0.000002
Saving checkpoint... 
Iteration: 385963814, states[0] = -86.981937, states[40]= 0.000002
Saving checkpoint... 
Iteration: 394796197, states[0] = -86.737299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 403636238, states[0] = -20.794079, states[40]= 0.000286
Saving checkpoint... 
Iteration: 412561282, states[0] = 22.909592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420257339, states[0] = -86.569408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428606499, states[0] = 1.931082, states[40]= 0.000090
Saving checkpoint... 
Iteration: 436821692, states[0] = -86.807844, states[40]= 0.000002
Saving checkpoint... 
Iteration: 443162253, states[0] = -43.295430, states[40]= 0.000237
Saving checkpoint... 
Iteration: 451122400, states[0] = -9.023772, states[40]= 0.000192
Saving checkpoint... 
Iteration: 459523131, states[0] = 31.594702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467990045, states[0] = -86.987916, states[40]= 0.000002
Saving checkpoint... 
Iteration: 476196748, states[0] = -84.625612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484571182, states[0] = 18.986595, states[40]= 0.000002
Saving checkpoint... 
Iteration: 492712928, states[0] = -86.244131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501113854, states[0] = -2.613279, states[40]= 0.000148
Saving checkpoint... 
Iteration: 510191880, states[0] = -80.516393, states[40]= 0.000002
Saving checkpoint... 
Iteration: 518627383, states[0] = -13.252714, states[40]= 0.000191
Saving checkpoint... 
Iteration: 526988395, states[0] = -86.983724, states[40]= 0.000002
Saving checkpoint... 
Iteration: 535365526, states[0] = -86.885752, states[40]= 0.000002
Saving checkpoint... 
Iteration: 543941059, states[0] = -86.959780, states[40]= 0.000002
Saving checkpoint... 
Iteration: 552473140, states[0] = -86.976104, states[40]= 0.000002
Saving checkpoint... 
Iteration: 560893555, states[0] = -86.919424, states[40]= 0.000002
Saving checkpoint... 
Iteration: 569102585, states[0] = 4.119133, states[40]= 0.000065
Saving checkpoint... 
Iteration: 577843536, states[0] = -86.846418, states[40]= 0.000002
Saving checkpoint... 
Iteration: 586359499, states[0] = -86.873496, states[40]= 0.000002
Saving checkpoint... 
Iteration: 594759193, states[0] = -86.568449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603370800, states[0] = -86.889131, states[40]= 0.000002
Saving checkpoint... 
Iteration: 611250819, states[0] = -86.520911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 619645040, states[0] = -27.850280, states[40]= 0.000531
Saving checkpoint... 
Iteration: 627867061, states[0] = -86.882345, states[40]= 0.000002
Saving checkpoint... 
Iteration: 636559731, states[0] = 23.490761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645306609, states[0] = -86.754492, states[40]= 0.000002
Saving checkpoint... 
Iteration: 653810794, states[0] = -86.765972, states[40]= 0.000002
Saving checkpoint... 
Iteration: 662658312, states[0] = -39.464848, states[40]= 0.000337
Saving checkpoint... 
Iteration: 671129293, states[0] = -14.894389, states[40]= 0.000193
Saving checkpoint... 
Iteration: 679272669, states[0] = -86.628604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 688064069, states[0] = 21.853947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 696097389, states[0] = 6.858611, states[40]= 0.000040
Saving checkpoint... 
Iteration: 704326741, states[0] = -86.803485, states[40]= 0.000002
Saving checkpoint... 
Iteration: 712757591, states[0] = -86.552559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720959320, states[0] = -86.959396, states[40]= 0.000002
Saving checkpoint... 
Iteration: 729435090, states[0] = -86.944662, states[40]= 0.000002
Saving checkpoint... 
Iteration: 737752464, states[0] = -86.522529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 746496378, states[0] = -86.973194, states[40]= 0.000002
Saving checkpoint... 
Iteration: 754851350, states[0] = -86.849723, states[40]= 0.000002
Saving checkpoint... 
Iteration: 763312464, states[0] = -86.763863, states[40]= 0.000002
Saving checkpoint... 
Iteration: 772038850, states[0] = 29.799536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780573396, states[0] = 18.062799, states[40]= 0.000003
Saving checkpoint... 
Iteration: 788741017, states[0] = -86.448970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 798002294, states[0] = 21.745973, states[40]= 1.736899
Saving checkpoint... 
Iteration: 807170581, states[0] = -51.835013, states[40]= 0.000091
Saving checkpoint... 
Iteration: 815680903, states[0] = -64.010280, states[40]= 0.000018
Saving checkpoint... 
Iteration: 824671148, states[0] = -52.443894, states[40]= 0.000084
Saving checkpoint... 
Iteration: 833179134, states[0] = -61.700634, states[40]= 0.000025
Saving checkpoint... 
Iteration: 841831277, states[0] = -86.805258, states[40]= 0.000002
Saving checkpoint... 
Iteration: 850272443, states[0] = -86.617026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858631959, states[0] = -17.173018, states[40]= 0.000208
Saving checkpoint... 
Iteration: 867276790, states[0] = -86.634925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 875893746, states[0] = -86.900465, states[40]= 0.000002
Saving checkpoint... 
Iteration: 884178271, states[0] = -60.609429, states[40]= 0.000029
Saving checkpoint... 
Iteration: 892611233, states[0] = -0.885730, states[40]= 0.000126
Saving checkpoint... 
Iteration: 901458410, states[0] = -86.947955, states[40]= 0.000002
Saving checkpoint... 
Iteration: 910625467, states[0] = -11.564809, states[40]= 0.000191
Saving checkpoint... 
Iteration: 919195841, states[0] = -84.077703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927785771, states[0] = -86.667236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 936380546, states[0] = -86.881570, states[40]= 0.000002
Saving checkpoint... 
Iteration: 944791164, states[0] = -86.686009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 953325925, states[0] = -86.786287, states[40]= 0.000002
Saving checkpoint... 
Iteration: 961830675, states[0] = -86.796579, states[40]= 0.000002
Saving checkpoint... 
Iteration: 970573114, states[0] = 18.187373, states[40]= 0.000003
Saving checkpoint... 
Iteration: 979058925, states[0] = 23.793709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987670583, states[0] = -51.811720, states[40]= 0.000090
Saving checkpoint... 
Iteration: 996231962, states[0] = -86.373114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004662913, states[0] = -43.880560, states[40]= 0.000221
Saving checkpoint... 
Iteration: 1012812302, states[0] = -86.748091, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1020866976, states[0] = -86.858242, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1029277163, states[0] = -86.626445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1037980664, states[0] = -86.949800, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1046541374, states[0] = 29.223203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054938882, states[0] = -86.927369, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1063321539, states[0] = -86.769019, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1071475543, states[0] = -86.945657, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1079893453, states[0] = -86.887713, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1088517697, states[0] = 31.007276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097142905, states[0] = -26.082543, states[40]= 0.000482
Saving checkpoint... 
Iteration: 1105801866, states[0] = -86.711798, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1113712414, states[0] = -86.198463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122207008, states[0] = -86.104411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131413546, states[0] = -86.903881, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1140279084, states[0] = -86.627610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1149742265, states[0] = -86.434515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1158120364, states[0] = -7.320521, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1166559044, states[0] = 23.755048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174961104, states[0] = -86.932738, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1184047148, states[0] = 27.679711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192593975, states[0] = 8.597388, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1201340562, states[0] = -86.802494, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1210200108, states[0] = -85.555302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218564118, states[0] = 21.848284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1227181432, states[0] = -64.639909, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1236185857, states[0] = -71.135799, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1244861819, states[0] = -86.836893, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1253101327, states[0] = 4.824293, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1261693117, states[0] = -81.764103, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1269435741, states[0] = -86.912304, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1277735936, states[0] = -86.383834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1286858149, states[0] = -86.828556, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1295310629, states[0] = -86.726080, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1303636918, states[0] = -21.266704, states[40]= 0.000298
Saving checkpoint... 
Iteration: 1312516294, states[0] = 30.668093, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1321544044, states[0] = 28.549210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330325153, states[0] = -86.761361, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1338580101, states[0] = 15.147163, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1347049232, states[0] = 27.061680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355608051, states[0] = 1.074742, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1363967564, states[0] = -86.924420, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1372296289, states[0] = -86.677351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381029487, states[0] = 31.351653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388990700, states[0] = -86.932334, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1397183569, states[0] = -67.618815, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1405493509, states[0] = -86.932304, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1414350709, states[0] = -86.808314, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1422540333, states[0] = 29.480731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431328296, states[0] = -86.762463, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1439803815, states[0] = -86.697237, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1448175165, states[0] = -56.818659, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1456336049, states[0] = -86.777781, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1464847266, states[0] = -86.799095, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1473173936, states[0] = -55.419863, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1481587253, states[0] = 11.857312, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1490051650, states[0] = 26.305451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498510233, states[0] = 27.732876, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.804618
 - CaMKt in component CaMK (millimolar): 0.025538
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 8.095457
 - nass in component intracellular_ions (millimolar): 8.095613
 - ki in component intracellular_ions (millimolar): 143.248320
 - kss in component intracellular_ions (millimolar): 143.248281
 - cansr in component intracellular_ions (millimolar): 2.087061
 - cajsr in component intracellular_ions (millimolar): 2.024589
 - cai in component intracellular_ions (millimolar): 0.000097
 - m in component INa (dimensionless): 0.008181
 - hf in component INa (dimensionless): 0.659702
 - hs in component INa (dimensionless): 0.659671
 - j in component INa (dimensionless): 0.659496
 - hsp in component INa (dimensionless): 0.411636
 - jp in component INa (dimensionless): 0.659369
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.456094
 - hLp in component INaL (dimensionless): 0.222410
 - a in component Ito (dimensionless): 0.001076
 - iF in component Ito (dimensionless): 0.999462
 - iS in component Ito (dimensionless): 0.534998
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999462
 - iSp in component Ito (dimensionless): 0.578697
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877835
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999623
 - jca in component ICaL (dimensionless): 0.999941
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004014
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.507689
 - xs1 in component IKs (dimensionless): 0.332601
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997030
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
07:08:42 (13044): called boinc_finish(0)

</stderr_txt>
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