𝕏

Task 55510651

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_15_1
Workunit 26356440
Created 1 Jul 2024, 14:50:26 UTC
Sent 1 Jul 2024, 16:24:46 UTC
Report deadline 4 Jul 2024, 16:24:46 UTC
Received 3 Jul 2024, 8:13:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 45 min 30 sec
CPU time 2 hours 17 min 44 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.25 MB
Peak swap size 6.21 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_15.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_15_1_r1861710526_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_15_1_r1861710526_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 107.096747
     * GNaL_b in INaL: 0.006001
     * Gto_b in Ito: 0.082051
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031547
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.166569
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.857413
     * GKb_b in IKb: 0.003820
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033592
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8251630, states[0] = -86.473005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16673480, states[0] = -36.230845, states[40]= 0.000238
Saving checkpoint... 
Iteration: 25457763, states[0] = -86.918989, states[40]= 0.000002
Saving checkpoint... 
Iteration: 33791517, states[0] = -86.682735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 42209479, states[0] = -85.584214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50506891, states[0] = 24.704051, states[40]= -0.000000
Saving checkpoint... 
Iteration: 58723862, states[0] = -86.361925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67469667, states[0] = -86.985751, states[40]= 0.000002
Saving checkpoint... 
Iteration: 76257734, states[0] = -86.594180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85012772, states[0] = 29.788939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93496625, states[0] = -87.011800, states[40]= 0.000002
Saving checkpoint... 
Iteration: 101778174, states[0] = -86.700637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110464809, states[0] = -87.004519, states[40]= 0.000002
Saving checkpoint... 
Iteration: 118237260, states[0] = -86.491345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126985843, states[0] = -87.015916, states[40]= 0.000002
Saving checkpoint... 
Iteration: 135103890, states[0] = 4.028219, states[40]= 0.000056
Saving checkpoint... 
Iteration: 143499681, states[0] = -87.021883, states[40]= 0.000002
Saving checkpoint... 
Iteration: 151816690, states[0] = -86.831066, states[40]= 0.000002
Saving checkpoint... 
Iteration: 159984598, states[0] = -87.017232, states[40]= 0.000002
Saving checkpoint... 
Iteration: 168405886, states[0] = -86.970273, states[40]= 0.000002
Saving checkpoint... 
Iteration: 177228052, states[0] = -86.430681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185245994, states[0] = -86.549311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 193652423, states[0] = -32.327860, states[40]= 0.000488
Saving checkpoint... 
Iteration: 202387278, states[0] = -86.950896, states[40]= 0.000002
Saving checkpoint... 
Iteration: 210660779, states[0] = -39.802958, states[40]= 0.000300
Saving checkpoint... 
Iteration: 219589017, states[0] = 11.279161, states[40]= 0.000013
Saving checkpoint... 
Iteration: 227773541, states[0] = -86.687058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 236635704, states[0] = -18.995629, states[40]= 0.000219
Saving checkpoint... 
Iteration: 244899805, states[0] = -86.961936, states[40]= 0.000002
Saving checkpoint... 
Iteration: 253108406, states[0] = 1.401058, states[40]= 0.000084
Saving checkpoint... 
Iteration: 261584737, states[0] = 13.256733, states[40]= 0.000008
Saving checkpoint... 
Iteration: 269972421, states[0] = -87.008446, states[40]= 0.000002
Saving checkpoint... 
Iteration: 278143932, states[0] = -25.506053, states[40]= 0.000437
Saving checkpoint... 
Iteration: 286666997, states[0] = -45.893497, states[40]= 0.000164
Saving checkpoint... 
Iteration: 295819032, states[0] = -86.831704, states[40]= 0.000002
Saving checkpoint... 
Iteration: 304239998, states[0] = -86.506698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313219841, states[0] = -86.360883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321145465, states[0] = -26.707837, states[40]= 0.000472
Saving checkpoint... 
Iteration: 329222556, states[0] = -86.381793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337170898, states[0] = -49.918198, states[40]= 0.000104
Saving checkpoint... 
Iteration: 346247759, states[0] = -86.551746, states[40]= 0.000001
Saving checkpoint... 
Iteration: 354996144, states[0] = -87.012683, states[40]= 0.000002
Saving checkpoint... 
Iteration: 363165767, states[0] = -44.655626, states[40]= 0.000187
Saving checkpoint... 
Iteration: 371839627, states[0] = -86.872114, states[40]= 0.000002
Saving checkpoint... 
Iteration: 380266063, states[0] = -86.645516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388182512, states[0] = -63.484062, states[40]= 0.000018
Saving checkpoint... 
Iteration: 397025233, states[0] = 31.897040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405271273, states[0] = -86.667654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413167730, states[0] = -46.626414, states[40]= 0.000151
Saving checkpoint... 
Iteration: 421067022, states[0] = 20.863800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429526208, states[0] = 31.859030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437703742, states[0] = -85.971963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445974138, states[0] = -86.999628, states[40]= 0.000002
Saving checkpoint... 
Iteration: 454621138, states[0] = -6.946694, states[40]= 0.000165
Saving checkpoint... 
Iteration: 463054641, states[0] = 25.464943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471635147, states[0] = -18.535515, states[40]= 0.000210
Saving checkpoint... 
Iteration: 480206411, states[0] = -86.141442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489444204, states[0] = -86.982381, states[40]= 0.000002
Saving checkpoint... 
Iteration: 498648667, states[0] = -29.253043, states[40]= 0.000509
Saving checkpoint... 
Iteration: 506996022, states[0] = -87.004357, states[40]= 0.000002
Saving checkpoint... 
Iteration: 515748062, states[0] = -86.543975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523962580, states[0] = -86.990212, states[40]= 0.000002
Saving checkpoint... 
Iteration: 532926852, states[0] = -86.968775, states[40]= 0.000002
Saving checkpoint... 
Iteration: 540828617, states[0] = -86.840308, states[40]= 0.000002
Saving checkpoint... 
Iteration: 549070053, states[0] = 19.642181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 557833339, states[0] = -86.849400, states[40]= 0.000002
Saving checkpoint... 
Iteration: 565885659, states[0] = -86.929776, states[40]= 0.000002
Saving checkpoint... 
Iteration: 574996738, states[0] = -87.000892, states[40]= 0.000002
Saving checkpoint... 
Iteration: 583971856, states[0] = -86.991143, states[40]= 0.000002
Saving checkpoint... 
Iteration: 592925866, states[0] = -86.964804, states[40]= 0.000002
Saving checkpoint... 
Iteration: 601127126, states[0] = -11.768990, states[40]= 0.000172
Saving checkpoint... 
Iteration: 609926485, states[0] = -86.964313, states[40]= 0.000002
Saving checkpoint... 
Iteration: 618588565, states[0] = 11.493567, states[40]= 0.000013
Saving checkpoint... 
Iteration: 627072265, states[0] = 18.729098, states[40]= 0.000002
Saving checkpoint... 
Iteration: 635901718, states[0] = -86.942503, states[40]= 0.000002
Saving checkpoint... 
Iteration: 644383211, states[0] = -86.922656, states[40]= 0.000002
Saving checkpoint... 
Iteration: 653147483, states[0] = -28.284387, states[40]= 0.000500
Saving checkpoint... 
Iteration: 661882583, states[0] = -86.920978, states[40]= 0.000002
Saving checkpoint... 
Iteration: 669595516, states[0] = 8.164286, states[40]= 0.000026
Saving checkpoint... 
Iteration: 678466380, states[0] = -86.983573, states[40]= 0.000002
Saving checkpoint... 
Iteration: 686654211, states[0] = -33.885076, states[40]= 0.000454
Saving checkpoint... 
Iteration: 694979788, states[0] = -86.988335, states[40]= 0.000002
Saving checkpoint... 
Iteration: 703029341, states[0] = 31.620529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711757279, states[0] = -86.583704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720035081, states[0] = 30.784890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728251092, states[0] = -86.549351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735926711, states[0] = -86.957593, states[40]= 0.000002
Saving checkpoint... 
Iteration: 744364670, states[0] = -86.893224, states[40]= 0.000002
Saving checkpoint... 
Iteration: 752959801, states[0] = -86.976374, states[40]= 0.000002
Saving checkpoint... 
Iteration: 761419608, states[0] = -86.950919, states[40]= 0.000002
Saving checkpoint... 
Iteration: 769433728, states[0] = -86.960583, states[40]= 0.000002
Saving checkpoint... 
Iteration: 777641449, states[0] = -23.536080, states[40]= 0.000361
Saving checkpoint... 
Iteration: 786231618, states[0] = -86.423246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794848792, states[0] = -86.865499, states[40]= 0.000002
Saving checkpoint... 
Iteration: 803393580, states[0] = -86.925321, states[40]= 0.000002
Saving checkpoint... 
Iteration: 811416598, states[0] = -86.945840, states[40]= 0.000002
Saving checkpoint... 
Iteration: 819667120, states[0] = -45.960373, states[40]= 0.000162
Saving checkpoint... 
Iteration: 828016872, states[0] = 31.175558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836347996, states[0] = -86.861831, states[40]= 0.000002
Saving checkpoint... 
Iteration: 845083831, states[0] = 13.682902, states[40]= 0.000007
Saving checkpoint... 
Iteration: 853842100, states[0] = -86.850259, states[40]= 0.000002
Saving checkpoint... 
Iteration: 862508373, states[0] = 26.491516, states[40]= -0.000000
Saving checkpoint... 
Iteration: 870913179, states[0] = -86.939790, states[40]= 0.000002
Saving checkpoint... 
Iteration: 879441320, states[0] = -86.959382, states[40]= 0.000002
Saving checkpoint... 
Iteration: 888193993, states[0] = -80.900239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 896508241, states[0] = 26.356208, states[40]= -0.000000
Saving checkpoint... 
Iteration: 904880766, states[0] = -86.905527, states[40]= 0.000002
Saving checkpoint... 
Iteration: 913853004, states[0] = -86.866039, states[40]= 0.000002
Saving checkpoint... 
Iteration: 922530058, states[0] = 31.546353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931773636, states[0] = -86.648516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940233704, states[0] = -86.429060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948592062, states[0] = 9.847811, states[40]= 0.000018
Saving checkpoint... 
Iteration: 957184734, states[0] = -66.493369, states[40]= 0.000012
Saving checkpoint... 
Iteration: 965697091, states[0] = -83.872809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974001376, states[0] = 33.593750, states[40]= 2.169533
Saving checkpoint... 
Iteration: 982539203, states[0] = 29.945134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991203888, states[0] = -85.945108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000104116, states[0] = 3.786848, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1008237319, states[0] = -86.449627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017233659, states[0] = -86.424418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025906645, states[0] = -86.925713, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1034610074, states[0] = 0.470201, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1042989716, states[0] = -86.973038, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1051266346, states[0] = -86.609387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1059477170, states[0] = -86.967422, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1067535579, states[0] = 30.700497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074830507, states[0] = -86.814982, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1082601238, states[0] = 5.299620, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1090173212, states[0] = -52.295660, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1097473055, states[0] = -86.963667, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1104818781, states[0] = -86.786487, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1112446732, states[0] = -86.949855, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1120292891, states[0] = -86.711021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128335165, states[0] = -86.821726, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1136558964, states[0] = 23.954721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144139449, states[0] = -21.940326, states[40]= 0.000300
Saving checkpoint... 
Iteration: 1151666980, states[0] = -45.780409, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1159195309, states[0] = -82.331002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167157243, states[0] = -36.511195, states[40]= 0.000385
Saving checkpoint... 
Iteration: 1175301691, states[0] = -86.735994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1184322490, states[0] = -86.790993, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1193358446, states[0] = -86.859343, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1202246819, states[0] = -86.498159, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1210338438, states[0] = -86.823717, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1218392519, states[0] = -86.901524, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1225543842, states[0] = 28.799718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233282057, states[0] = -86.665818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240634101, states[0] = -17.604974, states[40]= 0.000194
Saving checkpoint... 
Iteration: 1248314917, states[0] = -86.768857, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1256223138, states[0] = -86.333803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263581939, states[0] = 14.549089, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1272486292, states[0] = -86.959320, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1281319831, states[0] = -86.779304, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1290254900, states[0] = -86.538756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1298519078, states[0] = 31.611277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307373016, states[0] = -86.873812, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1316320824, states[0] = -86.779793, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1324981657, states[0] = -86.954746, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1333906862, states[0] = -86.909085, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1342677532, states[0] = -57.102103, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1351477249, states[0] = -86.951560, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1359298398, states[0] = -86.715685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1366437484, states[0] = -86.930433, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1374124642, states[0] = -9.646988, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1382605255, states[0] = 3.190605, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1390924498, states[0] = -86.920235, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1400031334, states[0] = 31.397314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409116066, states[0] = -3.250941, states[40]= 0.000135
Saving checkpoint... 
Iteration: 1417127271, states[0] = -11.823170, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1426444366, states[0] = -86.931375, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1435723481, states[0] = -86.326311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444838589, states[0] = -86.811123, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1453283364, states[0] = -86.658589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1461934808, states[0] = -86.923507, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1470079372, states[0] = 15.697113, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1478399216, states[0] = -86.894059, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1487009080, states[0] = 27.175452, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1495923390, states[0] = -86.913690, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.827418
 - CaMKt in component CaMK (millimolar): 0.025105
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.037916
 - nass in component intracellular_ions (millimolar): 8.038068
 - ki in component intracellular_ions (millimolar): 143.363224
 - kss in component intracellular_ions (millimolar): 143.363186
 - cansr in component intracellular_ions (millimolar): 2.047109
 - cajsr in component intracellular_ions (millimolar): 1.981800
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008162
 - hf in component INa (dimensionless): 0.660543
 - hs in component INa (dimensionless): 0.660513
 - j in component INa (dimensionless): 0.660342
 - hsp in component INa (dimensionless): 0.412547
 - jp in component INa (dimensionless): 0.660219
 - mL in component INaL (dimensionless): 0.000230
 - hL in component INaL (dimensionless): 0.456548
 - hLp in component INaL (dimensionless): 0.222338
 - a in component Ito (dimensionless): 0.001075
 - iF in component Ito (dimensionless): 0.999464
 - iS in component Ito (dimensionless): 0.533021
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999464
 - iSp in component Ito (dimensionless): 0.576607
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.875951
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999604
 - jca in component ICaL (dimensionless): 0.999938
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003829
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.509836
 - xs1 in component IKs (dimensionless): 0.335513
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997025
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
10:12:37 (6168): called boinc_finish(0)

</stderr_txt>
]]>


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