𝕏

Task 55510357

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_414_1
Workunit 26356293
Created 1 Jul 2024, 14:50:15 UTC
Sent 1 Jul 2024, 16:24:46 UTC
Report deadline 4 Jul 2024, 16:24:46 UTC
Received 2 Jul 2024, 21:43:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 42 min 44 sec
CPU time 2 hours 19 min 7 sec
Validate state Valid
Credit 45.86
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.06 MB
Peak swap size 6.21 MB
Peak disk usage 0.94 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_414.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_414_1_r126344372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Schmidt_3000-conf_414_1_r126344372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.248477
     * GNaL_b in INaL: 0.005593
     * Gto_b in Ito: 0.085478
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031496
     * GKs_b in IKs: 0.001887
     * GK1_b in IK1: 0.163703
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.431360
     * GKb_b in IKb: 0.003816
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029230
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1498500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8763386, states[0] = -84.261637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 18165777, states[0] = -59.375314, states[40]= 0.000012
Saving checkpoint... 
Iteration: 26929018, states[0] = -84.091089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36087781, states[0] = 6.402334, states[40]= 0.000489
Saving checkpoint... 
Iteration: 44932096, states[0] = -84.035900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 53899445, states[0] = -84.022055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62540279, states[0] = -84.027941, states[40]= 0.000001
Saving checkpoint... 
Iteration: 71196885, states[0] = -84.028616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 80085165, states[0] = -84.009394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88899184, states[0] = -83.892762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 97238088, states[0] = -83.994511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106346857, states[0] = -83.986329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114502302, states[0] = -83.967902, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123369365, states[0] = -83.836894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131802062, states[0] = -83.982289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 139497229, states[0] = -83.973255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 148231034, states[0] = -83.983335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 156392826, states[0] = -83.868417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 164113683, states[0] = -83.993195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 171703725, states[0] = -84.000592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180237772, states[0] = -83.372508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188675727, states[0] = -83.983235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197243014, states[0] = -84.000341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 205488042, states[0] = -83.969129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 214005393, states[0] = -83.991213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 222868570, states[0] = -83.997376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231566538, states[0] = -83.981358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 240121519, states[0] = -13.186964, states[40]= 0.000709
Saving checkpoint... 
Iteration: 248986075, states[0] = -83.968405, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257418594, states[0] = -83.994803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265858258, states[0] = -83.808618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 274786411, states[0] = -83.607087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283277034, states[0] = -83.976716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292244046, states[0] = -83.978191, states[40]= 0.000001
Saving checkpoint... 
Iteration: 300925495, states[0] = -83.994157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 309359075, states[0] = -83.809880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317704023, states[0] = -83.979967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326030776, states[0] = -83.969590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 333775922, states[0] = -83.998724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342129005, states[0] = -19.836039, states[40]= 0.000559
Saving checkpoint... 
Iteration: 351012404, states[0] = 30.429684, states[40]= 0.023781
Saving checkpoint... 
Iteration: 359771264, states[0] = -83.976578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367823608, states[0] = -83.728610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376178204, states[0] = -83.980972, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384678909, states[0] = -83.996393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 393587408, states[0] = -83.985046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401705300, states[0] = -83.979534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 409787188, states[0] = -83.609425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417820228, states[0] = -83.997594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425961176, states[0] = -83.968345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 434601876, states[0] = -83.984617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 443011255, states[0] = -83.961234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451123729, states[0] = -83.983426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459911910, states[0] = -83.994082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467895668, states[0] = -83.970747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476240130, states[0] = -83.998112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 485109665, states[0] = -83.988703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493463143, states[0] = -83.968006, states[40]= 0.000001
Saving checkpoint... 
Iteration: 502077134, states[0] = -83.985637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510221037, states[0] = -83.262648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518866459, states[0] = -83.971753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 526865609, states[0] = -83.821021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 535397114, states[0] = -83.970425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 544182142, states[0] = -83.980114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553054695, states[0] = -83.986607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 561401744, states[0] = -83.875301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 569474534, states[0] = -83.990667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577811295, states[0] = -83.692241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 586247499, states[0] = -83.976788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595413503, states[0] = -83.969533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603737802, states[0] = -83.997590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 611953911, states[0] = -83.967894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 619975891, states[0] = -83.941914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 628321199, states[0] = -83.973270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636673669, states[0] = -83.995073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645135731, states[0] = -25.598572, states[40]= 0.000634
Saving checkpoint... 
Iteration: 653021688, states[0] = -83.964806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 661716948, states[0] = -83.221551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669602794, states[0] = -83.986853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 677703432, states[0] = -83.978547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 685704698, states[0] = -82.694246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693254537, states[0] = -83.460345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700615204, states[0] = -7.811636, states[40]= 0.000951
Saving checkpoint... 
Iteration: 707475423, states[0] = -83.990087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 715190054, states[0] = -83.979058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 724041515, states[0] = -83.986630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 731930939, states[0] = -83.968314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 740626941, states[0] = -83.982136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 749436065, states[0] = -83.991847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 757432321, states[0] = -83.968161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 765196865, states[0] = -80.510983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773453545, states[0] = -83.990914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 782336512, states[0] = -83.995723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790407420, states[0] = -83.969017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 798488595, states[0] = -83.948649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807127362, states[0] = -18.383311, states[40]= 0.000562
Saving checkpoint... 
Iteration: 815509480, states[0] = -83.987935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 823983353, states[0] = -83.945594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 832203757, states[0] = -83.977931, states[40]= 0.000001
Saving checkpoint... 
Iteration: 840626458, states[0] = -83.989740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 848928219, states[0] = -83.967965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857712371, states[0] = -83.977413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 866209783, states[0] = -83.995951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874765158, states[0] = -83.512424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882939168, states[0] = -83.991182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 891902242, states[0] = -83.992832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 900797056, states[0] = -83.996219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909489807, states[0] = -83.948881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 918043922, states[0] = 24.989821, states[40]= 0.000036
Saving checkpoint... 
Iteration: 926586212, states[0] = -83.983517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934468687, states[0] = -83.966082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 942776305, states[0] = -83.996329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 951986713, states[0] = -83.988570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 960544205, states[0] = -83.971684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 969144860, states[0] = -33.285730, states[40]= 0.000472
Saving checkpoint... 
Iteration: 977714953, states[0] = -83.976822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 985719290, states[0] = -83.245301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994676276, states[0] = -60.628800, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1003077504, states[0] = -83.983673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1011487403, states[0] = -83.947162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1020220606, states[0] = -83.256944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028845555, states[0] = -83.970656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1037299170, states[0] = -83.995652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046071244, states[0] = -83.978912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1055029451, states[0] = -83.966233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1063969093, states[0] = -83.935828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072347553, states[0] = -83.970402, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080515691, states[0] = -83.960678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089376559, states[0] = -83.837368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1097682983, states[0] = -83.977922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1106211117, states[0] = -83.995064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114834548, states[0] = -83.753742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1122876516, states[0] = -83.993002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1131432500, states[0] = -83.906585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1139260104, states[0] = -83.995644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1147216546, states[0] = -83.976086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155744195, states[0] = -83.995519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165045524, states[0] = -83.984710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173370431, states[0] = -83.826899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181677425, states[0] = -83.977872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1189827398, states[0] = -83.735429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198023154, states[0] = -83.985745, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206641690, states[0] = -83.990119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215601940, states[0] = -83.984590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224113965, states[0] = -6.842184, states[40]= 0.000982
Saving checkpoint... 
Iteration: 1232438330, states[0] = -83.989867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240616326, states[0] = -8.712468, states[40]= 0.000915
Saving checkpoint... 
Iteration: 1248457269, states[0] = -83.926821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256559012, states[0] = -83.983652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1264241117, states[0] = -83.974456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272750659, states[0] = -83.995108, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280968426, states[0] = -83.964744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1289461825, states[0] = -83.988507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1298245454, states[0] = -83.994977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306590282, states[0] = 6.576558, states[40]= 0.000552
Saving checkpoint... 
Iteration: 1314357229, states[0] = -83.802317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1323254642, states[0] = -83.458344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331726685, states[0] = -83.974881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340484379, states[0] = -83.987181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349281884, states[0] = -83.994699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1357767553, states[0] = -83.521766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365762892, states[0] = -83.994763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1373830932, states[0] = -83.969947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1382073467, states[0] = -83.978141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1390319643, states[0] = -83.970377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398200316, states[0] = -81.860007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406183358, states[0] = -83.992690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414170997, states[0] = -83.977290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1423121982, states[0] = -83.979741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1431818011, states[0] = -83.993717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439978550, states[0] = -83.963748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1448622036, states[0] = -83.979639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1457402551, states[0] = -83.990626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1465487917, states[0] = -83.963304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1473497755, states[0] = -83.950851, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481470989, states[0] = -83.987307, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489643123, states[0] = -31.818399, states[40]= 0.000526
Saving checkpoint... 
Iteration: 1498285873, states[0] = -83.971468, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.838689
 - CaMKt in component CaMK (millimolar): 0.002758
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 6.270178
 - nass in component intracellular_ions (millimolar): 6.270287
 - ki in component intracellular_ions (millimolar): 145.609183
 - kss in component intracellular_ions (millimolar): 145.609170
 - cansr in component intracellular_ions (millimolar): 1.679302
 - cajsr in component intracellular_ions (millimolar): 1.679461
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.011016
 - hf in component INa (dimensionless): 0.543544
 - hs in component INa (dimensionless): 0.543548
 - j in component INa (dimensionless): 0.543565
 - hsp in component INa (dimensionless): 0.300679
 - jp in component INa (dimensionless): 0.543575
 - mL in component INaL (dimensionless): 0.000405
 - hL in component INaL (dimensionless): 0.380707
 - hLp in component INaL (dimensionless): 0.210483
 - a in component Ito (dimensionless): 0.001314
 - iF in component Ito (dimensionless): 0.999096
 - iS in component Ito (dimensionless): 0.947858
 - ap in component Ito (dimensionless): 0.000670
 - iFp in component Ito (dimensionless): 0.999096
 - iSp in component Ito (dimensionless): 0.962066
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990773
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003522
 - xrf in component IKr (dimensionless): 0.000015
 - xrs in component IKr (dimensionless): 0.087057
 - xs1 in component IKs (dimensionless): 0.072330
 - xs2 in component IKs (dimensionless): 0.000303
 - xk1 in component IK1 (dimensionless): 0.996956
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:42:56 (10460): called boinc_finish(0)

</stderr_txt>
]]>


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