𝕏

Task 55510190

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_14_0
Workunit 26356210
Created 1 Jul 2024, 14:50:10 UTC
Sent 1 Jul 2024, 16:24:46 UTC
Report deadline 4 Jul 2024, 16:24:46 UTC
Received 3 Jul 2024, 0:50:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 43 min 35 sec
CPU time 2 hours 17 min 22 sec
Validate state Valid
Credit 51.71
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.15 MB
Peak swap size 6.22 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_14.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_14_0_r1772203800_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pieske_1000-conf_14_0_r1772203800_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.356603
     * GNaL_b in INaL: 0.006036
     * Gto_b in Ito: 0.085940
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032326
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.162802
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.243793
     * GKb_b in IKb: 0.003828
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034755
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8757196, states[0] = -87.033561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17573595, states[0] = -1.691117, states[40]= 0.003935
Saving checkpoint... 
Iteration: 25893348, states[0] = -87.045974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34625564, states[0] = -51.103702, states[40]= 0.000021
Saving checkpoint... 
Iteration: 42590425, states[0] = -14.024883, states[40]= 0.001587
Saving checkpoint... 
Iteration: 51656020, states[0] = -85.213976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60957273, states[0] = -87.003712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69491080, states[0] = -87.002313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77996096, states[0] = -86.997860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85907534, states[0] = -86.976782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94967465, states[0] = -86.986776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103599710, states[0] = -21.590843, states[40]= 0.000818
Saving checkpoint... 
Iteration: 112507752, states[0] = 23.674109, states[40]= 0.079800
Saving checkpoint... 
Iteration: 120192407, states[0] = -86.758071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128952729, states[0] = -86.977342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137710617, states[0] = -86.792455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145469868, states[0] = -86.978772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154689473, states[0] = -86.748608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162813370, states[0] = -86.919431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171728050, states[0] = -86.821696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180019276, states[0] = 21.934804, states[40]= 0.008942
Saving checkpoint... 
Iteration: 188607363, states[0] = -28.960057, states[40]= 0.000468
Saving checkpoint... 
Iteration: 196812117, states[0] = -86.917531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205598302, states[0] = -19.811330, states[40]= 0.000933
Saving checkpoint... 
Iteration: 214431983, states[0] = -86.969222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223033274, states[0] = 18.135140, states[40]= 0.005190
Saving checkpoint... 
Iteration: 232024864, states[0] = 20.698710, states[40]= 0.006310
Saving checkpoint... 
Iteration: 240475758, states[0] = -86.977257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248180444, states[0] = -86.725609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256982210, states[0] = -86.978126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264860351, states[0] = -86.945189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273657261, states[0] = -84.810477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282174141, states[0] = -86.697972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290387512, states[0] = -86.956075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299042522, states[0] = 14.747444, states[40]= 0.004814
Saving checkpoint... 
Iteration: 307797788, states[0] = -86.905585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316005580, states[0] = 25.443423, states[40]= 0.130610
Saving checkpoint... 
Iteration: 324828973, states[0] = -86.928276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333138524, states[0] = -62.466842, states[40]= 0.000003
Saving checkpoint... 
Iteration: 341015720, states[0] = 22.479344, states[40]= 0.013998
Saving checkpoint... 
Iteration: 349275709, states[0] = -86.884603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357638170, states[0] = -62.026892, states[40]= 0.000003
Saving checkpoint... 
Iteration: 365889101, states[0] = -86.956543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374741030, states[0] = -86.840831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383360648, states[0] = -86.945161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391929551, states[0] = -86.968182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401037543, states[0] = 16.624378, states[40]= 0.004959
Saving checkpoint... 
Iteration: 408691069, states[0] = -86.749858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417056567, states[0] = 9.055992, states[40]= 0.004698
Saving checkpoint... 
Iteration: 425725838, states[0] = -86.816577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434324681, states[0] = -86.925458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442546200, states[0] = 13.308308, states[40]= 0.004761
Saving checkpoint... 
Iteration: 450589157, states[0] = -10.764895, states[40]= 0.002140
Saving checkpoint... 
Iteration: 458589099, states[0] = -10.710801, states[40]= 0.002151
Saving checkpoint... 
Iteration: 466566154, states[0] = 4.706970, states[40]= 0.004556
Saving checkpoint... 
Iteration: 474979549, states[0] = -86.977487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484112728, states[0] = -34.337816, states[40]= 0.000256
Saving checkpoint... 
Iteration: 492316871, states[0] = -86.920150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500545633, states[0] = 13.532481, states[40]= 0.004767
Saving checkpoint... 
Iteration: 509250064, states[0] = -86.853594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517780660, states[0] = -86.889580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526516419, states[0] = 22.389618, states[40]= 0.012584
Saving checkpoint... 
Iteration: 533850218, states[0] = -86.940038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542707402, states[0] = -86.782767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550604356, states[0] = -25.896926, states[40]= 0.000605
Saving checkpoint... 
Iteration: 558787376, states[0] = -86.896083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566157764, states[0] = -85.032376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573977494, states[0] = -86.977114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581184377, states[0] = -86.735213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590227456, states[0] = -86.819193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598173787, states[0] = -86.695080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606771709, states[0] = -86.880096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615428909, states[0] = -86.967868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623543359, states[0] = 14.423563, states[40]= 0.004799
Saving checkpoint... 
Iteration: 632895897, states[0] = -86.958633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641557146, states[0] = 8.807764, states[40]= 0.004694
Saving checkpoint... 
Iteration: 651006767, states[0] = 24.256766, states[40]= 0.100913
Saving checkpoint... 
Iteration: 659428357, states[0] = -86.967705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667389227, states[0] = -86.956366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676177136, states[0] = -86.713854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684001920, states[0] = 38.859032, states[40]= 0.114726
Saving checkpoint... 
Iteration: 692334905, states[0] = -86.931581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700808937, states[0] = -86.914216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709122243, states[0] = -44.121735, states[40]= 0.000063
Saving checkpoint... 
Iteration: 717461399, states[0] = -86.974425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725637933, states[0] = -61.733321, states[40]= 0.000003
Saving checkpoint... 
Iteration: 733958872, states[0] = -86.973969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742574934, states[0] = 0.014133, states[40]= 0.004143
Saving checkpoint... 
Iteration: 750880805, states[0] = -86.953262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759552146, states[0] = 10.909471, states[40]= 0.004722
Saving checkpoint... 
Iteration: 767991487, states[0] = -86.978912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776443397, states[0] = -86.970966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785009709, states[0] = 23.151171, states[40]= 0.049210
Saving checkpoint... 
Iteration: 793782288, states[0] = -86.891005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802223905, states[0] = -86.812985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810910929, states[0] = -86.963066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819232437, states[0] = -86.827215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827858268, states[0] = -86.943739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836529577, states[0] = 19.346867, states[40]= 0.005522
Saving checkpoint... 
Iteration: 844689751, states[0] = -86.746772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852617715, states[0] = -39.412622, states[40]= 0.000127
Saving checkpoint... 
Iteration: 861387400, states[0] = -86.955587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869762693, states[0] = -86.869525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878452202, states[0] = -86.972639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886767909, states[0] = -86.875632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895009438, states[0] = 23.201252, states[40]= 0.052596
Saving checkpoint... 
Iteration: 903552862, states[0] = 10.613976, states[40]= 0.004718
Saving checkpoint... 
Iteration: 912344280, states[0] = -86.936677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921031945, states[0] = 18.585064, states[40]= 0.005292
Saving checkpoint... 
Iteration: 929784470, states[0] = -86.893043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937719120, states[0] = -86.804445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946034754, states[0] = 17.625604, states[40]= 0.005096
Saving checkpoint... 
Iteration: 954587698, states[0] = -9.425417, states[40]= 0.002407
Saving checkpoint... 
Iteration: 962906389, states[0] = -86.961648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971199818, states[0] = -86.767407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980103046, states[0] = -24.576736, states[40]= 0.000666
Saving checkpoint... 
Iteration: 988682780, states[0] = -86.731110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997361542, states[0] = -86.945124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005491160, states[0] = -86.978700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014615120, states[0] = -36.761843, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1022921579, states[0] = -86.965771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031682507, states[0] = -86.730401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040474021, states[0] = -86.976256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048955623, states[0] = -86.973155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057956169, states[0] = -86.973249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067003619, states[0] = 30.023290, states[40]= 0.166166
Saving checkpoint... 
Iteration: 1075529935, states[0] = 19.234861, states[40]= 0.005482
Saving checkpoint... 
Iteration: 1084317272, states[0] = -86.920004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093081337, states[0] = -4.211785, states[40]= 0.003473
Saving checkpoint... 
Iteration: 1101888965, states[0] = -86.955963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110176153, states[0] = -86.709105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117898727, states[0] = -86.959195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126885116, states[0] = -86.954581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136011586, states[0] = 22.906697, states[40]= 0.031498
Saving checkpoint... 
Iteration: 1144620858, states[0] = -42.667325, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1152908923, states[0] = -86.962250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161482387, states[0] = -86.977401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170302236, states[0] = -86.908626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178494017, states[0] = -86.978940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186992238, states[0] = -86.978708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195318300, states[0] = -86.920638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203435818, states[0] = -86.969035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211517868, states[0] = 22.178957, states[40]= 0.010395
Saving checkpoint... 
Iteration: 1219782995, states[0] = -86.891395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228958768, states[0] = -86.973596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237606426, states[0] = -27.981424, states[40]= 0.000511
Saving checkpoint... 
Iteration: 1246144008, states[0] = -69.716320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254584691, states[0] = -6.826129, states[40]= 0.002949
Saving checkpoint... 
Iteration: 1262723362, states[0] = -86.811710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270949119, states[0] = -86.971763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279053713, states[0] = 10.260667, states[40]= 0.004714
Saving checkpoint... 
Iteration: 1287836343, states[0] = -86.931990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296294746, states[0] = -86.902232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305600349, states[0] = -21.857023, states[40]= 0.000803
Saving checkpoint... 
Iteration: 1314474989, states[0] = -86.976207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323101053, states[0] = -22.567263, states[40]= 0.000764
Saving checkpoint... 
Iteration: 1332023951, states[0] = 20.933217, states[40]= 0.006554
Saving checkpoint... 
Iteration: 1340598174, states[0] = -19.661144, states[40]= 0.000945
Saving checkpoint... 
Iteration: 1348854294, states[0] = -86.941472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357282098, states[0] = -86.890411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365965916, states[0] = -86.974728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373965318, states[0] = -86.974622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382758208, states[0] = -86.863634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390802785, states[0] = -86.908911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399383923, states[0] = -86.953952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407676194, states[0] = -86.709085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415707046, states[0] = -86.781440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424008432, states[0] = 23.449796, states[40]= 0.067439
Saving checkpoint... 
Iteration: 1432084650, states[0] = -6.792199, states[40]= 0.002956
Saving checkpoint... 
Iteration: 1440893158, states[0] = -86.957150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449202993, states[0] = -86.773427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457991031, states[0] = -86.978359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466242601, states[0] = -86.842355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475010272, states[0] = 23.062709, states[40]= 0.042913
Saving checkpoint... 
Iteration: 1483440661, states[0] = -86.969886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492806472, states[0] = -86.911755, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.855315
 - CaMKt in component CaMK (millimolar): 0.006775
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.432142
 - nass in component intracellular_ions (millimolar): 6.432200
 - ki in component intracellular_ions (millimolar): 145.551395
 - kss in component intracellular_ions (millimolar): 145.551376
 - cansr in component intracellular_ions (millimolar): 1.294691
 - cajsr in component intracellular_ions (millimolar): 1.256958
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008139
 - hf in component INa (dimensionless): 0.661570
 - hs in component INa (dimensionless): 0.661559
 - j in component INa (dimensionless): 0.661496
 - hsp in component INa (dimensionless): 0.413723
 - jp in component INa (dimensionless): 0.661452
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.466681
 - hLp in component INaL (dimensionless): 0.241405
 - a in component Ito (dimensionless): 0.001073
 - iF in component Ito (dimensionless): 0.999467
 - iS in component Ito (dimensionless): 0.579264
 - ap in component Ito (dimensionless): 0.000546
 - iFp in component Ito (dimensionless): 0.999467
 - iSp in component Ito (dimensionless): 0.634031
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935724
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999894
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001529
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.404639
 - xs1 in component IKs (dimensionless): 0.241351
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997018
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:50:00 (13128): called boinc_finish(0)

</stderr_txt>
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