𝕏

Task 55509890

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_214_0
Workunit 26356061
Created 1 Jul 2024, 14:50:05 UTC
Sent 1 Jul 2024, 16:24:46 UTC
Report deadline 4 Jul 2024, 16:24:46 UTC
Received 3 Jul 2024, 8:30:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 47 min 10 sec
CPU time 2 hours 18 min 33 sec
Validate state Valid
Credit 45.22
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.28 MB
Peak swap size 6.20 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_214.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_214_0_r2042123796_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_6000-conf_214_0_r2042123796_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.971922
     * GNaL_b in INaL: 0.005816
     * Gto_b in Ito: 0.086315
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031592
     * GKs_b in IKs: 0.001928
     * GK1_b in IK1: 0.162171
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.201474
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030535
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8099244, states[0] = -94.062732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16187159, states[0] = -93.995654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24603427, states[0] = -93.949453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33067045, states[0] = 18.851961, states[40]= 0.001093
Saving checkpoint... 
Iteration: 41342244, states[0] = -93.888506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50192281, states[0] = -93.882171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58567436, states[0] = -93.888768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67677754, states[0] = -93.883986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75961685, states[0] = -93.905159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84289745, states[0] = -93.542034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92750601, states[0] = -93.868278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100896324, states[0] = -93.877190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109503155, states[0] = -93.885128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117768570, states[0] = -93.907598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126335239, states[0] = -93.674295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134857083, states[0] = -93.866631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143249303, states[0] = -93.871669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151402525, states[0] = -93.887361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159966651, states[0] = -93.902695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168097514, states[0] = 6.345842, states[40]= 0.003132
Saving checkpoint... 
Iteration: 176433682, states[0] = -93.869579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185614744, states[0] = -93.867998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193443717, states[0] = -93.885983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201530061, states[0] = -93.877265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210069200, states[0] = 18.202455, states[40]= 0.000994
Saving checkpoint... 
Iteration: 217919004, states[0] = -93.875772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226921482, states[0] = -93.875710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235221596, states[0] = -93.892880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243978796, states[0] = -93.901974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252592147, states[0] = -93.893688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260948478, states[0] = -93.865571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269385435, states[0] = -93.869795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277970682, states[0] = -93.874843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286564812, states[0] = -93.882632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294743889, states[0] = -93.906559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303664716, states[0] = -93.903005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312054465, states[0] = 23.475236, states[40]= 0.000446
Saving checkpoint... 
Iteration: 320663937, states[0] = -93.867327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329073651, states[0] = -93.873283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337691760, states[0] = -93.879700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346110599, states[0] = -93.896765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354204908, states[0] = -73.267942, states[40]= 0.000006
Saving checkpoint... 
Iteration: 362542133, states[0] = -93.868219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371443764, states[0] = -93.869068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380122477, states[0] = -93.872556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388432533, states[0] = -93.885917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397029192, states[0] = -93.899806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405373245, states[0] = -93.747129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413862722, states[0] = -93.865824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422407247, states[0] = -93.869328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431093190, states[0] = -93.872855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439486762, states[0] = -93.884353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448074030, states[0] = -93.897999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456466775, states[0] = -93.845686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464730781, states[0] = -93.866609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473145963, states[0] = -93.872107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481517938, states[0] = -93.883475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490127244, states[0] = -93.895900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499084362, states[0] = -93.897520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507248769, states[0] = -93.360944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516199846, states[0] = -68.083061, states[40]= 0.000014
Saving checkpoint... 
Iteration: 524345843, states[0] = -93.869768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532909922, states[0] = -93.875375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541813946, states[0] = -93.877001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550186145, states[0] = -93.893619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559078809, states[0] = -93.897636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567249779, states[0] = -93.366084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575128021, states[0] = -93.872168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583683986, states[0] = -93.879463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592077241, states[0] = -93.897643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600644001, states[0] = -93.900612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608856274, states[0] = -93.865548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617413113, states[0] = -93.868956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625796995, states[0] = -93.877174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634352182, states[0] = -93.887891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642851079, states[0] = -93.905334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650951906, states[0] = -93.864909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659418707, states[0] = -93.868835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668038474, states[0] = -93.873216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676658315, states[0] = -93.879859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685195391, states[0] = -93.893066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693944695, states[0] = -93.902460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702691728, states[0] = -93.904146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711181565, states[0] = -53.140362, states[40]= 0.000159
Saving checkpoint... 
Iteration: 719809047, states[0] = -93.865668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727496965, states[0] = -93.883618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735982798, states[0] = -93.901014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744131343, states[0] = -15.821258, states[40]= 0.001811
Saving checkpoint... 
Iteration: 752365674, states[0] = -93.869198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761545492, states[0] = -93.867543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769757301, states[0] = -93.877687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778032676, states[0] = -93.899056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786620689, states[0] = -93.897481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794372501, states[0] = -93.869062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803136651, states[0] = -93.871689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811714308, states[0] = -93.878468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820223899, states[0] = -93.891831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828821305, states[0] = -93.905599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837819066, states[0] = -93.905618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845902775, states[0] = -93.864880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854631944, states[0] = -93.866701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863159413, states[0] = -93.871308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871408017, states[0] = -93.885836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880325321, states[0] = -93.888335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888908253, states[0] = -93.903363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897513156, states[0] = -93.869524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905518062, states[0] = -93.867542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914150108, states[0] = -93.871340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922622002, states[0] = -93.880262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931120312, states[0] = -93.895449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938200067, states[0] = -93.870695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945368990, states[0] = -93.739300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953171198, states[0] = -93.871017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961156278, states[0] = -93.894051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968520513, states[0] = -93.867418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976614755, states[0] = -93.880339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984124112, states[0] = -10.066095, states[40]= 0.002559
Saving checkpoint... 
Iteration: 991445656, states[0] = -93.884573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999667527, states[0] = -93.902098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007376458, states[0] = -93.868678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014081658, states[0] = 13.327999, states[40]= 0.001792
Saving checkpoint... 
Iteration: 1021066701, states[0] = -93.897354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028576749, states[0] = -93.866854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036802686, states[0] = -93.876403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045390353, states[0] = -93.886071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054026545, states[0] = -93.898845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062572052, states[0] = -93.888104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071213740, states[0] = -84.294301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078874299, states[0] = -93.875078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086567573, states[0] = -93.886988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094384248, states[0] = -93.868460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101633039, states[0] = -93.898570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109427289, states[0] = -93.868024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116528958, states[0] = -93.875338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123909160, states[0] = -93.874429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133288056, states[0] = -93.869385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141997563, states[0] = -93.873036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150808872, states[0] = -93.876106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158812919, states[0] = -93.905183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166762898, states[0] = -93.865250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175695477, states[0] = -93.865707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184349601, states[0] = -93.868659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193085811, states[0] = -93.871717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201380081, states[0] = -93.886124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210461854, states[0] = -93.883773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218236835, states[0] = -93.266061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225451998, states[0] = -93.884019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233621334, states[0] = -93.896848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242592018, states[0] = -93.892051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250914118, states[0] = -93.864155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259927809, states[0] = -93.864060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268653073, states[0] = -93.865869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277278471, states[0] = -93.869256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286496818, states[0] = -93.867108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295122723, states[0] = -93.871069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304012459, states[0] = -93.872556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313180028, states[0] = -93.870327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321705632, states[0] = -93.877819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329785684, states[0] = -93.905131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337836465, states[0] = -93.864490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347308233, states[0] = -93.599680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356004681, states[0] = 32.037778, states[40]= 0.374084
Saving checkpoint... 
Iteration: 1364345250, states[0] = -93.868412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372628278, states[0] = -93.879392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381107338, states[0] = -93.895214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389849681, states[0] = -93.904158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397500962, states[0] = -93.866891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405440679, states[0] = -93.884041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413221207, states[0] = -91.102080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421278120, states[0] = -93.869026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429124576, states[0] = -93.894482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436743820, states[0] = -93.864942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445633826, states[0] = -93.865728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453758259, states[0] = -93.876561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461943127, states[0] = -93.901273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470140259, states[0] = -22.626742, states[40]= 0.002303
Saving checkpoint... 
Iteration: 1478471427, states[0] = -93.867021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486807311, states[0] = -93.875589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495438341, states[0] = -93.883961, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.739242
 - CaMKt in component CaMK (millimolar): 0.001326
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.701226
 - nass in component intracellular_ions (millimolar): 6.701352
 - ki in component intracellular_ions (millimolar): 145.161924
 - kss in component intracellular_ions (millimolar): 145.161915
 - cansr in component intracellular_ions (millimolar): 1.838509
 - cajsr in component intracellular_ions (millimolar): 1.838388
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004069
 - hf in component INa (dimensionless): 0.858318
 - hs in component INa (dimensionless): 0.858318
 - j in component INa (dimensionless): 0.858320
 - hsp in component INa (dimensionless): 0.686254
 - jp in component INa (dimensionless): 0.858320
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.697450
 - hLp in component INaL (dimensionless): 0.501830
 - a in component Ito (dimensionless): 0.000674
 - iF in component Ito (dimensionless): 0.999840
 - iS in component Ito (dimensionless): 0.999218
 - ap in component Ito (dimensionless): 0.000344
 - iFp in component Ito (dimensionless): 0.999840
 - iSp in component Ito (dimensionless): 0.999695
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999518
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005538
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000597
 - xs1 in component IKs (dimensionless): 0.014822
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997626
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:30:31 (5740): called boinc_finish(0)

</stderr_txt>
]]>


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