𝕏

Task 55509856

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_514_0
Workunit 26356044
Created 1 Jul 2024, 14:50:00 UTC
Sent 1 Jul 2024, 16:24:46 UTC
Report deadline 4 Jul 2024, 16:24:46 UTC
Received 3 Jul 2024, 6:41:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 41 min 48 sec
CPU time 2 hours 18 min 23 sec
Validate state Valid
Credit 45.64
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.25 MB
Peak swap size 6.21 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_514.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_514_0_r1326631865_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Drouin_ENDO_4000-conf_514_0_r1326631865_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.300143
     * GNaL_b in INaL: 0.005604
     * Gto_b in Ito: 0.088216
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031764
     * GKs_b in IKs: 0.001905
     * GK1_b in IK1: 0.161279
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.413866
     * GKb_b in IKb: 0.003771
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035876
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8470492, states[0] = -94.050706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16717651, states[0] = -94.019456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25368990, states[0] = -93.962763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33435206, states[0] = -93.941000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41743724, states[0] = -93.922968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50411715, states[0] = -93.846313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58857126, states[0] = -93.943487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67098448, states[0] = -93.933050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75523224, states[0] = -93.917768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83976457, states[0] = -93.907691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92867364, states[0] = -93.940475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101335310, states[0] = -93.922547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110330996, states[0] = -93.710568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118407290, states[0] = -93.835249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126786003, states[0] = -93.941665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135166874, states[0] = -93.928327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143733612, states[0] = -93.911367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152015270, states[0] = 31.297899, states[40]= 0.009553
Saving checkpoint... 
Iteration: 160272799, states[0] = -93.526103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168429772, states[0] = -93.857183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176985515, states[0] = -93.935480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185844499, states[0] = -93.908953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194119290, states[0] = -7.905375, states[40]= 0.002876
Saving checkpoint... 
Iteration: 202642122, states[0] = -93.936441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210807702, states[0] = -93.941028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219286224, states[0] = -93.923540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227349377, states[0] = -93.921362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235658311, states[0] = -93.912719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244049902, states[0] = 24.621372, states[40]= 0.000341
Saving checkpoint... 
Iteration: 252796048, states[0] = -93.941077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261660420, states[0] = -93.912602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269912328, states[0] = -93.907479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278229737, states[0] = -93.255854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286438107, states[0] = -93.863942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294211994, states[0] = -87.906307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303259827, states[0] = -93.924267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311543615, states[0] = -93.915381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320220542, states[0] = -92.524616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329273015, states[0] = -93.923729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337454243, states[0] = -93.917815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346223105, states[0] = -92.901829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354856532, states[0] = -93.939582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363938126, states[0] = -93.906801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372327061, states[0] = -93.700225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380703130, states[0] = -93.939922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389134022, states[0] = -93.928866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397513852, states[0] = -93.915975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406478224, states[0] = -93.890930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415417813, states[0] = -93.918719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423574045, states[0] = -93.914314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432075809, states[0] = 15.146207, states[40]= 0.001370
Saving checkpoint... 
Iteration: 440259855, states[0] = -93.469005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448974955, states[0] = -93.935198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457143560, states[0] = -93.928320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464817212, states[0] = -93.940233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473736936, states[0] = -93.910380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482356957, states[0] = -93.762663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490591389, states[0] = -93.928868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498845237, states[0] = -93.939533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507464397, states[0] = -93.917106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515315032, states[0] = -93.921808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523885396, states[0] = -93.907340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532771780, states[0] = -93.940579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541218169, states[0] = -93.925226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549315242, states[0] = -93.921719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558003154, states[0] = 37.214501, states[40]= 0.621773
Saving checkpoint... 
Iteration: 566703411, states[0] = -93.939482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574831493, states[0] = -93.939676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582945297, states[0] = -93.936032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591564097, states[0] = -93.914164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600125638, states[0] = -13.042265, states[40]= 0.002008
Saving checkpoint... 
Iteration: 608133212, states[0] = -19.237903, states[40]= 0.001727
Saving checkpoint... 
Iteration: 616586970, states[0] = -93.927755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625215467, states[0] = -93.925125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633867825, states[0] = -93.907394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641883196, states[0] = -93.907094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650065766, states[0] = 19.024860, states[40]= 0.000827
Saving checkpoint... 
Iteration: 658191955, states[0] = -65.169570, states[40]= 0.000020
Saving checkpoint... 
Iteration: 666649561, states[0] = -93.935988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674892933, states[0] = -93.937695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683781747, states[0] = -93.908939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692126396, states[0] = -13.669591, states[40]= 0.001927
Saving checkpoint... 
Iteration: 700658823, states[0] = -93.936674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708961885, states[0] = -93.935086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717345125, states[0] = -93.920305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725949433, states[0] = -93.905730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734486195, states[0] = -93.894418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742691887, states[0] = -93.938585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751307549, states[0] = -93.921494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759709732, states[0] = -93.910275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767867546, states[0] = -93.907075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776398723, states[0] = -93.823578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784482646, states[0] = -93.892431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792767584, states[0] = -93.939959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800982114, states[0] = -93.934061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809508765, states[0] = -93.915117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818453912, states[0] = -93.874659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827402365, states[0] = -93.918198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836072876, states[0] = 16.306623, states[40]= 0.001190
Saving checkpoint... 
Iteration: 844955303, states[0] = -93.935013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853001284, states[0] = -93.933162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861162916, states[0] = -93.926577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869889898, states[0] = -93.906420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878514747, states[0] = -93.906970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886895289, states[0] = -93.937104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895124136, states[0] = -93.928038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903682018, states[0] = -93.910545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912150493, states[0] = -32.317530, states[40]= 0.001915
Saving checkpoint... 
Iteration: 920544379, states[0] = -93.916944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928901879, states[0] = -93.936778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937387458, states[0] = -93.918400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945897797, states[0] = -93.906094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954566677, states[0] = -93.922691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962797910, states[0] = -93.939332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970947054, states[0] = -93.935027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979596146, states[0] = -93.912407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987999705, states[0] = -93.904268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996638693, states[0] = -93.934157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005612025, states[0] = -93.911950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013783490, states[0] = -93.908103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021740457, states[0] = -93.908976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029713491, states[0] = -93.909538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037904250, states[0] = -93.905756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045697535, states[0] = -93.909852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053986951, states[0] = -93.904314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062762431, states[0] = -93.939306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071066180, states[0] = -93.929973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079582886, states[0] = -93.912499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087845806, states[0] = -93.906705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096381015, states[0] = -93.799704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104204353, states[0] = -78.415354, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1112920178, states[0] = -93.935687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120890137, states[0] = -93.936709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129031226, states[0] = -93.931270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137397926, states[0] = -93.917585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145569037, states[0] = -93.912693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154394546, states[0] = -93.817563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162405248, states[0] = -93.830197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170451945, states[0] = -93.872407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178972027, states[0] = -93.933549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186663722, states[0] = -93.935866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195435999, states[0] = -93.916278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203925384, states[0] = -93.904983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212211873, states[0] = -87.774288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220416742, states[0] = -93.842266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228566129, states[0] = -93.921901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236820637, states[0] = -93.938302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245266703, states[0] = -93.921737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253369998, states[0] = -93.918193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261653961, states[0] = -93.910324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270262928, states[0] = -93.480834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278950166, states[0] = -93.934162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287334735, states[0] = -93.919271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295735270, states[0] = -93.908423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304194310, states[0] = -67.322552, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1312635960, states[0] = -93.933110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321794446, states[0] = -93.907136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329838546, states[0] = -93.906256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337717324, states[0] = -93.908708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346167588, states[0] = -45.452156, states[40]= 0.000441
Saving checkpoint... 
Iteration: 1354209461, states[0] = -85.043463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1362832628, states[0] = -93.937746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370577687, states[0] = -93.924103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379068476, states[0] = -93.929133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387558237, states[0] = -93.912387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395423727, states[0] = -93.916164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403931682, states[0] = -93.904389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412908674, states[0] = -93.935372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421509842, states[0] = -93.913604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430140957, states[0] = -25.189520, states[40]= 0.002328
Saving checkpoint... 
Iteration: 1439185137, states[0] = -93.924312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447969439, states[0] = -93.903645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456198793, states[0] = -71.828647, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1464255556, states[0] = -93.446504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473100819, states[0] = -93.927583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481330431, states[0] = -93.918946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489935377, states[0] = -93.904117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498117629, states[0] = -6.626264, states[40]= 0.003098
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.778991
 - CaMKt in component CaMK (millimolar): 0.002086
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.736737
 - nass in component intracellular_ions (millimolar): 6.736860
 - ki in component intracellular_ions (millimolar): 145.121198
 - kss in component intracellular_ions (millimolar): 145.121187
 - cansr in component intracellular_ions (millimolar): 1.835089
 - cajsr in component intracellular_ions (millimolar): 1.834945
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004053
 - hf in component INa (dimensionless): 0.859111
 - hs in component INa (dimensionless): 0.859111
 - j in component INa (dimensionless): 0.859115
 - hsp in component INa (dimensionless): 0.687662
 - jp in component INa (dimensionless): 0.859118
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.698603
 - hLp in component INaL (dimensionless): 0.502647
 - a in component Ito (dimensionless): 0.000672
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.991378
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.996533
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996456
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005287
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008172
 - xs1 in component IKs (dimensionless): 0.041417
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997617
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:41:42 (9868): called boinc_finish(0)

</stderr_txt>
]]>


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